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      • A Novel Injectable pH–Temperature Sensitive Hydrogel Containing Chitosan–Insulin Electrosprayed Nanosphere Composite for an Insulin Delivery System in Type I Diabetes Treatment

        Thuy An Trinh,Thai Minh Duy Le,Hoang Gia Vinh Ho,Thi Cam Thach To,Vu Viet Linh Nguyen,Dai Phu Huynh,Doo Sung Lee 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.1

        Faculty of Materials Technology, Ho Chi Minh University of Technology (HCMUT)/Vietnam National University Ho Chi Minh City; <sup>1</sup>School of Chemical Engineering and Theragnostic Macromolecules Research Center, Sungkyunkwan University; <sup>2</sup>Vietnam National University Ho Chi Minh City/National Key Laboratory of Polymer and Composite Materials, Ho Chi Minh University of Technology, Vietnam National University; <sup>3</sup>Faculty of Materials Technology, Ho Chi Minh University of Technology (HCMUT)/ Vietnam National University Ho Chi Minh City/Research Center for Polymeric Materials, Ho Chi Minh University of Technology, Vietnam National University In this research, a novel insulin composite delivery system was prepared and characterized. Insulin drug was loading in chitoshan nanospheres using electrospraying method, a pH- and temperature-sensitive biodegradable hydrogel, which is an oligomer serine-poly(lactide)-poly(ethylene glycol)-poly (lactide)-oligomer serine (OS-PLA-PEG-PLA-OS) pentablock copolymer was used as a matrix to containing chitosan–insulin electro sprayed nanospheres (CIN). The properties of the OS-PLA-PEG-PLA-OS pentablock copolymer and the chitosan–insulin nanoparticles such as sol-gel transition, degradation in vitro and in vivo were characterized. The results showed that the chitosan–insulin nanospheres uniformly distributed in the matrix had a reinforcing effect on the mechanical properties and prolonged the degradation time of the hydrogel depot under body conditions. In addition, the cytotoxicity experiment results indicate that the composite could be used as a biomaterial for drug delivery system. The composite solutions accommodating different concentrations of the chitosan–insulin nanospheres were subcutaneously injected into induced diabetic BALB/c mice to study the in vivo insulin-release profile. The result showed that insulin concentrations in blood plasma were maintained at a steady-state level. Furthermore, the bio-properties of the insulin were retained and it showed a blood glucose level reducing effect for more than 60 hours after injection to a streptozotocin (STZ)-induced diabetic mouse model. The results suggested that this injectable pH–temperature sensitive hydrogel containing chitosan– insulin electro sprayed nanosphere composites has promising potential applications for type 1 diabetes treatment.

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        Determinants Influencing Consumers Purchasing Intention for Sustainable Fashion: Evidence from Ho Chi Minh City

        Thuy Thi Hai HO,Trinh Ngoc Phuong VU,Hieu Minh VU 한국유통과학회 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.11

        This paper investigates factors impacting on sustainable fashion buying intention of consumers by reviewing studies about the topic and conducting a survey with consumers in Ho Chi Minh City. In detail, firstly, an interview with 15 respondents was conducted to check the understanding of concepts and questions and, secondly, the study used the convenient sampling method, with 172 samples collected and analyzed, of which young respondents accounted for the majority of the sample. The respondents tend to go shopping many times in a year, with the number of people buying fashion products from every week to every two months accounting for 65.2% totally. The findings suggest that the firms should prioritize strategies that can improve customer attitude toward sustainable fashion, making them feel good, pleasant, satisfied and favorable when engaging in sustainable fashion consumption. This study concludes that consumers need more information to enable them to make better ethical decisions. This study proposes that the major channels that consumers use to seek sustainable product information include public education, peer influence, and corporate marketing information about the products. This study concludes that public education and corporate marketing information on green consumption education is effective for improving consumer sustainable buying intention.

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        Determinants of Implementation of Enterprise Resource Planning System: A Case Study in Vietnam

        Xuan Hiep NGUYEN,Thi Cam Loan NGUYEN,Xuan Dao MAI,Thi To Loan BUI,Thi Tra Giang TRAN,Thuy Trinh HO,Thi Huyen NGUYEN 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.4

        Under the pressure of business competition and effectiveness, more and more organizations in the world are likely to apply modern software such as enterprise resource planning (ERP) which can help them to create better organizing practice, better managing capabilities of administrators, and better operations of personnel. In Vietnam, many firms are afraid to install it and the number of firms adopting this software is limited mainly due to the insufficient scientific evidence of the successful implementation of ERP. This study aims to identify and measure the factors influencing the successful implementation of ERP of firms in Vietnam. Qualitative research methodology combined with quantitative research methodology is used. The data are surveyed with 343 administrators of 45 organizations that have successfully deployed ERP in Ha Noi and Ho Chi Minh cities. Of these 19 were excluded from analyses due to unsatisfactory responses, and only 324 were used for statistical processing. The collected data were processed by using the SPSS software. The result of the study shows that there are six factors affecting the successful implementation of ERP of firms in Vietnam, (ranked in descending order of importance), they are top management commitment and support, business process re-engineering, user involvement, project management board, vendor support, and suitability of software and hardware.

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