Poster Session : Cancer Biology ; Alternative regulation of the breast cell proliferation by thyroxine

( Talat Saatov ),( Anvar Abduvaliev ) 한국생화학분자생물학회 (구 한국생화학회) 2007 생화학분자생물학회 춘계학술발표논문집 Vol.2007 No.-

Aromatherapy for Sexual Problems in Menopausal Women: A Systematic Review and Meta-analysis

( Talat Khadivzadeh ),( Mona Najaf Najafi ),( Masumeh Ghazanfarpour ),( Morvarid Irani ),( Fatemeh Rajab Dizavandi ),( Khatereh Shariati ) 대한폐경학회 2018 대한폐경학회지 Vol.24 No.1

Objectives: The aim of the present systematic review and meta-analysis is the exploration of the potential evidence of the effectiveness of aromatherapy products on the sexual function of menopausal women. Methods: From inception to December 2017, the search process was performed using the MEDLINE and Scopus databases and the Cochrane Library regarding the trials on the effectiveness of herbal-medicine aromatherapy on the sexual function of menopausal women. Results: Three of the trials comprise suitable data for inclusion in the meta-analysis. According to the meta-analysis, it is possible to improve the standardized mean difference (SMD) of the sexual desire up to 0.56 in the aromatherapy group compared with the control group (SMD = 0.56; P < 0.001; heterogeneity; I² = 42%; P = 0.141). According to one of the trials, the serum-estrogen level of two different doses did not change in the neroli oil inhalation group compared with the almond-oil group. Conclusions: Both aromatherapy with neroli oil or lavender (monopreparation) and combined-oil aromatherapy with lavender, fennel, geranium, and rose significantly improved human sexual function; however, a significant change of the serum-estrogen level was not detected. The findings of the present review should be presented cautiously because of the corresponding limitations such as the lack of a standardized tool, the lack of intention-to-treat reporting, the low study amount, and the short-term follow-up. (J Menopausal Med 2018;24:56-61)

Cultural Barriers Influencing Midwives’ Sexual Conversation with Menopausal Women

( Talat Khadivzadeh ),( Masumeh Ghazanfarpour ),( Robab Latifnejad Roudsari ) 대한폐경학회 2018 대한폐경학회지 Vol.24 No.3

Objectives: The present study aimed to determine the barriers influencing the sexual conversation. Methods: In this descriptive cross-sectional study, 200 midwives were selected through convenience sampling method from private and public clinics in Mashhad, North East of Iran. A self-structured questionnaire was used to collect the study data. Results: The mean age of subjects was 39.58 ± 8.12 years with 13.49 ± 7.59 years of work experience. A number of cultural conditions act as an inhibitory force for the midwives to address sexual issues with menopausal women. Menopausal women visit a doctor at the acute stage when emotional and physical problems make sexual discussion difficult for the midwives (86.5%). Other related causes for not having proper sexual conversation were insufficient knowledge (51.4%), inadequate education provided via public media through health providers (83.5%), midwives or their patient’s shame (51.5%), and attempt to get help from traditional healers, friends, relatives and supplicants instead of midwifery staff (78.5%). Also, we found that sexual workshops, communication workshops, and work experiences had a significant influence in changing the views of midwives. Conclusions: Cultural barriers prevent the patients and providers from communicating effectively with each other, thus highlighting the need for sexual and communication workshops for the health care providers. (J Menopausal Med 2018;24:210-216)

A Systematic Review and Meta-analysis on the Effect of Herbal Medicine to Manage Sleep Dysfunction in Periand Postmenopause

( Talat Khadivzadeh ),( Somayeh Abdolahian ),( Masumeh Ghazanfarpour ),( Leila Kargarfard ),( Fatemeh Rajab Dizavandi ),( Imaneh Khorsand ) 대한폐경학회 2018 대한폐경학회지 Vol.24 No.2

Objectives: Some conventional medications used to treat insomnia, such as benzodiazepine, non-benzodiazepine, and hormone therapy, are associated with side effects. Therefore, there is a growing interest in the use of herbal medicine. The aim of this systematic review is to assess the effects herbal medicines have on sleep disorders of peri- and postmenopausal women. Methods: Three databases were searched including MEDLINE, Scopus, and the Cochrane Library from inception to March 2018. Results: Six trials assessed the effect of soy on sleep disorders. Forrest plot for 2 studies showed that the standardized mean difference (SMD) of the sleep problems was lower in the soy group than the placebo group (SMD = -0.996; P < 0.001; 95% confidence interval, -1.42 to -0.563). Three trials showed soy had no significant effect on sleep disorders and one study showed a positive effect on sleep disorders. Accordingly, it is difficult to reach a definite conclusion regarding the effects of soy on sleep disorders based on these findings. According to a trial, significant beneficial effect associated with taking Schisandra chinensis. Findings suggested that some herbal medicines like red clover, lavender combined with bitter orange and pin bark extract had attenuating effects on sleep disorders. After intake of 530 mg of valerian twice a day for one month, statistically significant effects were observed regarding the quality of sleep of postmenopausal women. Conclusions: The present systematic review and meta-analysis found inadequate evidence to draw conclusions regarding the effectiveness of herbal medications, especially soy. (J Menopausal Med 2018;24:92-99)

Effect of Fennel on the Health Status of Menopausal Women: A Systematic and Meta-analysis

( Talat Khadivzadeh ),( Mona Najaf Najafi ),( Leila Kargarfard ),( Masumeh Ghazanfarpour ),( Fatemeh Rajab Dizavandi ),( Imaneh Khorsand ) 대한폐경학회 2018 대한폐경학회지 Vol.24 No.1

Objectives: The aim of the present study is the systematic and critical investigation of the effectiveness of fennel on the climacteric symptoms among menopausal females. Methods: A search of the trials studying the effect of fennel on menopausal females was conducted in 2017 using the MEDLINE and Scopus databases and the Cochrane Library with the following keywords: fennel, Foeniculum vulgare, and menopause. Results: Fennel combined with officinalis is more effective in the attenuating of sleep disorders compared to Citalopram. The comparison of these two groups regarding the mean bone mineral density and bone mineral content (P = 0.14, P = 0.504); the total hip femoral (P = 0.42, P = 0.66); the trochanter (P = 0.075, P = 0.07); the intertrochanter (P = 0.84, P = 0.93); and the femoral neck (P = 0.43, P = 0.64) did not show any significant statistical differences; however, a statistically significant difference regarding the vasomotor symptoms (P < 0.01) was found. The other significant differences are related to the values of the total cholesterol (P = 0.103); low-density lipoprotein cholesterol, or LDL-C (P = 0.104); high-density lipoprotein cholesterol, or HDL-C (P = 0.266); triglyceride (P = 0.679); body weight (P = 0.212); body mass index (P = 0.041); waist and hip circumferences (P = 0.365); and fat distribution (P = 0.337) between the two groups. The standardized mean difference (SMD) values of sexual activity (SMD = 0.638; P < 0.001), and maturation value (SMD = 0.601; P = 0.003) are highly significant among the fennel-treated women compared with the placebo group. Conclusions: According to the findings of the present study, fennel is important in the relieving of vasomotor symptoms, vaginal itching, dryness, dyspareunia, sexual function, sexual satisfaction, and sleep distribution. (J Menopausal Med 2018;24:67-74)

Evaluation of the role of ischemia modified albumin in neonatal hypoxic-ischemic encephalopathy

Talat, Mohamed A.,Saleh, Rabab M.,Shehab, Mohammed M.,Khalifa, Naglaa A.,Sakr, Maha Mahmoud Hamed,Elmesalamy, Walaa M. The Korean Pediatric Society 2020 Clinical and Experimental Pediatrics (CEP) Vol.63 No.8

Background: Birth asphyxia is a leading cause of neonatal mortality. Ischemia-modified albumin (IMA) levels may have a predictive role in the identification and prevention of hypoxic disorders, as they increase in cases of ischemia of the liver, heart, brain, bowel, and kidney. Purpose: This study aimed to assess the value of IMA levels as a diagnostic marker for neonatal hypoxic-ischemic encephalopathy (HIE). Methods: Sixty newborns who fulfilled 3 or more of the clinical and biochemical criteria and developed HIE as defined by Levene staging were included in our study as the asphyxia group. Neonates with congenital malformation, systemic infection, intrauterine growth retardation, low-birth weight, cardiac or hemolytic disease, family history of neurological diseases, congenital or perinatal infections, preeclampsia, diabetes, and renal diseases were excluded from the study. Sixty healthy neonates matched for gestational age and with no maternal history of illness, established respiration at birth, and an Apgar score ≥7 at 1 and 5 minutes were included as the control group. IMA was determined by double-antibody enzyme-linked immunosorbent assay of a cord blood sample collected within 30 minutes after birth. Results: Cord blood IMA levels were higher in asphyxiated newborns than in controls (250.83±36.07 pmol/mL vs. 120.24±38.9 pmol/mL). Comparison of IMA levels by HIE stage revealed a highly significant difference among them (207.3±26.65, 259.28±11.68, 294.99±4.41 pmol/mL for mild, moderate, and severe, respectively). At a cutoff of 197.6 pmol/mL, the sensitivity was 84.5%, specificity was 86%, positive predictive value was 82.8%, negative predictive value was 88.3%, and area under the curve was 0.963 (P<0.001). Conclusion: IMA levels can be a reliable marker for the early diagnosis of neonatal HIE and can be a predictor of injury severity.

A New Approach On The Curvature Dependent Energy For Elastic Curves in a Lie Group

Talat Korpinar,Ridvan Cem Demirkol 호남수학회 2017 호남수학학술지 Vol.39 No.4

Elastica is known as classical curve that is a solution of variational problem, which minimize a thin inextensible wire's bending energy. Studies on elastica has been conducted in Euclidean space firstly, then it has been extended to Riemannian manifold by giving different characterizations. In this paper, we focus on energy of the elastic curve in a Lie group. We attepmt to compute its energy by using geometric description of the curvature and the torsion of the trajectory of the elastic curve of the trajectory of the moving particle in the Lie group. Finally, we also investigate the relation between energy of the elastic curve and energy of the same curve in Frenet vector fields in the Lie group.

Weighted Erlang and Lomax Distributions

Talat Yasmin,Muhammad Aslam,Jaffer Hussain,Chi-Hyuck Jun 대한산업공학회 2017 Industrial Engineeering & Management Systems Vol.16 No.3

Two new families of weighted Erlang and Lomax probability distributions are developed. Various properties including the moments and the bias in the estimated mean of a weighted distribution are derived. As applications of these distributions, time truncated acceptance sampling plans are designed to obtain the minimum sample size and the acceptance number for un-weighted and weighted distributions, where various pre-assigned producer’s and consumer’s risks, various ratios of true mean to the specified mean life, and various test termination time multipliers are considered. A real data set is analyzed to illustrate the proposed time-truncated sampling plan.

On New Fermi Walker Derivative Of Biharmonic Particles In Heisenberg Spacetime

Talat Korpinar 호남수학회 2019 호남수학학술지 Vol.41 No.1

In practical applications play an new important role timelike biharmonic particle by Fermi-Walker derivative. In this article, we get a innovative interpretation about timelike biharmonic particle by means of Fermi-Walker derivative and parallelism in Heisenberg spacetime. With this new representation, we derive necessary and sufficient condition of the given particle to be the inextensible flow. Moreover, we provide several characterizations designed for this particles in Heisenberg spacetime.

A NEW CONSTRUCTION OF BIENERGY AND BIANGLE IN LORENTZ 5-SPACE

( Talat Korpinar ),( Yasin Unluturk ) 호남수학회 2021 호남수학학술지 Vol.43 No.1

In this study, we firstly compute the energies and the angles of Frenet vector fields in Lorentz 5-space L⁵. Then we obtain the bienergies and biangels of Frenet vector fields in L⁵ by using the values of energies and angles. Finally, we present the relations among energies, angles, bienergies, and biangles with graphics.