Green Grinding with Innovative Wheel Topography

Taghi Tawakoli,Amir Daneshi,이달호 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.

Reduction or elimination of coolant-lubricants in machining processes is of significant interest for ecological and economical reasons. However, the desire to eliminate fluid usage in grinding processes represents a considerable challenge in moving towards green grinding due to the high energy input and high heat flux generated within the grinding zone. In order to perform the efficient grinding process without thermal damages, the chip formation needs to be optimized so that the friction between the grinding wheel and workpiece is minimized. Structured wheels, the idea introduced and developed by KSF (Institute of Grinding and Precision Technology) in recent years, show a great potential to approach the process with optimum chip formation condition. The concept is based on the reduction of static cutting edges through creating a specific structure on the wheel surface. This leads to a larger chip thickness and consequently lower friction during the grain-workpiece engagement. The experiments conducted by the structured wheels prove the lower grinding forces and energy as compared to those performed by normal wheels. This paper is aiming to take a step towards the green manufacturing technology through benefiting from these great advantages in plunge cylindrical dry grinding, in which the heat generation is a crucial factor. The experiments carried out with CBN structured wheels resulted lower grinding forces and energy as well as workpiece surface and subsurface temperatures as compared to when using the normal wheels.

How Human Aspects Impress Agile Software Development Transition and Adoption

Taghi Javdani Gandomani,Hazura Zulzalil,Abdul Azim Abdul Ghani,Abu Bakar Md. Sultan,Khaironi Yatim Sharif 보안공학연구지원센터 2014 International Journal of Software Engineering and Vol.8 No.1

A Case Study Research on Software Cost Estimation Using Experts’ Estimates, Wideband Delphi, and Planning Poker Technique

Taghi Javdani Gandomani,Koh Tieng Wei,Abdulelah Khaled Binhamid 보안공학연구지원센터 2014 International Journal of Software Engineering and Vol.8 No.11

This Article shows a Case Study research that is performed to compare effectiveness of the Planning Poker and Wideband Delphi in two case studies. Although, Wide Band Delphi has been proposed many years ago and has enough supports in both industry and academic area but, Planning Poker is somewhat new. The study showed that applying these techniques in two companies which were using expert’s view for software cost estimation, increased the accuracy of cost estimation. Also, the results showed that Planning Poker led to better accuracy comparing to Wideband Delphi. However, this accuracy is not too much than Wideband Delphi, it was important that Planning Poker led to reducing financial risks of the projects comparing to Wideband Delphi. The study also showed that both Wideband Delphi and Planning Poker reduced the underestimates significantly.

Investigation of BAX and BCL2 expression and apoptosis in a resveratrol- and prednisolone-treated human T-ALL cell line, CCRF-CEM

Taghi Khanzadeh,Majid Farshdousti Hagh,Mehdi Talebi,Bahman Yousefi,Ako Azimi,Abbas Ali Hossein pour feizi,Behzad Baradaran 대한혈액학회 2018 Blood Research Vol.53 No.1

BackgroundThe numerous side effects and chemo-resistance of conventional chemical drugs in thetreatment of malignancies have led to consideration of the anti-cancer properties of naturalproducts. In the present study, we aimed to explore the apoptotic effect of two naturalcomponents, resveratrol and prednisolone, on the T acute lymphoblastic leukemia (ALL)cell line, CCRF-CEM. Our findings suggested the incorporation of these natural agentsinto drug regimens to treat patients with ALL. MethodsIn this study, we investigated the effect of different doses of resveratrol (15, 50 and 100μM) and prednisolone (700 μM) on BAX (apoptosis promoter) and BCL2 (apoptosis inhibitor)expressions following 24 and 48 hours of treatment on CCRF-CEM cells, usingreal-time PCR, and on apoptosis induction using flow cytometry. ResultsThe results showed a time- and dose-dependent increase in BAX expression and a decreasein BCL2 expression. Apoptosis was induced in CCRF-CEM cells treated with resveratroland prednisolone for 24 and 48 hours. Combined resveratrol and prednisolone treatmentshowed synergistic effects on the overexpression of BAX and the downregulationof BCL2. The drug combination had a greater influence on apoptosis induction comparedwith either drug administered alone after 48 hours of treatment. ConclusionThe results of this study suggested that resveratrol exhibited a remarkable efficacy to improvethe influence of glucocorticoids drugs, especially prednisolone, to induce apoptosisin the CCRF-CEM cell line.

The Essential Prerequisites of Agile Transition and Adoption: a Grounded Theory Approach

( Taghi Javdani Gandomani ),( Mina Ziaei Nafchi ) 한국인터넷정보학회 2016 인터넷정보학회논문지 Vol.17 No.5

Prevalence of Agile methods in software companies is increasing dramatically. Software companies need to employ these methods to overcome the inherent challenges of traditional methods. However, transitioning to Agile approach is a topic of debate and there is no unique and well-defined transition model or framework yet. Although some research studies have addressed barriers and strengths behind the successful Agile deployment, it seems that this process still needs to be studied more in depth. The rationale behind this is the socio-technical nature of Agile transition and adoption. Particularly, the challenges and problems that software companies are facing during Agile transition, show that this process in more difficult than expected. Conducting a large-scale research study revealed that Agile transition and adoption process needs to be supported by several critical prerequisites. This study adopted a Ground Theory with the participation of 49 Agile experts from 13 different countries and empirically identified seven transition prerequisites. These prerequisites focus on the different aspects of the transition. The main aim of this paper is proposing these prerequisites and theoretical and practical implication of these prerequisites. Providing these prerequisites before moving to Agile increases chance of success in Agile transition and adoption and leads to fewer challenges during the change process.

Prediction of Stock Market Using an Ensemble Learning-based Intelligent Model

Mohammad-Taghi Faghihi-Nezhad,Behrouz Minaei-Bidgoli 대한산업공학회 2018 Industrial Engineeering & Management Systems Vol.17 No.3

AI-based models have shown that stock market is predictable despite its uncertainty and fluctuating nature. Research in this field has further dealt with predicting the next step price amount and less attention has been paid to the prediction of the next movement of price. However, in practice, the necessary requisite for decision-making and use of the results of prediction lies in considering the predictable trend of stock movement along with predicting stock price. Considering the widespread search in the literature on the matter, this paper takes into account, for the first time, two criteria of direction and price simultaneously for the prediction of the stock price. The proposed model has two stages and is developed based on ensemble learning and meta-heuristic optimization algorithms. The first stage predicts the direction of the next price movement. At the second stage, such prediction and other input variables create a new training dataset and the stock price is predicted. At each stage, in order to optimize the results, genetic algorithm (GA) optimization and particle swarm optimization (PSO) are applied. Evaluation of the results, on the real data of stock price, indicates that the proposed model has higher accuracy than other models used in the literature.

Investigation of the range of motion of the shoulder joint in subjects with rotator cuff arthropathy while performing daily activities

Mohammad Taghi Karimi,Sahar Khademi 대한견주관절의학회 2021 대한견주관절의학회지 Vol.24 No.2

Background: Patients who have rotator cuff arthropathy experience a limited range of motion (ROM) of the shoulder joint and experience problems in performing their daily activities; however, no evidence is available to suggest the exact ROM of the shoulder joint in this population. Therefore, this study sought to determine the degree of motion of the shoulder joint in three planes during different activities. Methods: Five subjects with rotator cuff injuries participated in this study. The motion of the shoulder joints on both the involved and normal sides was assessed by a motion analysis system while performing forward abduction (task 1), flexion (task 2), and forward flexion (task 3). The OpenSIM software program was used to determine the ROM of the shoulder joints on both sides. The difference between the ranges of motion was determined using a two-sample t-test. Results: The ROMs of the shoulder joint in task 1 were 93.5°±16.5°, 72.1°±2.6°, and 103.9°±25.7° for flexion, abduction, and rotation, respectively, on the normal side and 28°±19.8°, 31°±31.56°, and 48°±33.5° on the involved side (p<0.05). There was no significant difference between the flexion/extension and rotation movements of the shoulder joint when performing task 1. However, the difference between flexion and rotation movements of the shoulder joints for the second task was significant (p>0.05). Conclusions: Those with rotator cuff arthropathy have functional limitations due to muscle weakness and paralysis, especially during the vertical reaching task. However, although these individuals have decreased ROM for transverse reaching tasks, the reduction was not significant.

Lack of Association between Herpes Simplex Virus Type 2 Infection and Cervical Cancer - Taq Man Realtime PCR Assay Findings

Farivar, Taghi Naserpour,Johari, Pouran,Shafei, Shilan,Najafipour, Reza,Reza, Najafipour Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1

Background: About one third of the human population suffer cancer during their lifetime and more than 20% of total morbidity is related to neoplasia. Cervical cancer is generally the most common cancer in developing countries and the second most common in women globally. The role of human papilloma viruses viruses in its induction is clear. However, the involvement of hepres simplex virus type 2 (HSV-2) is controversial. Therefore a survey was conducted of the prevalence of HSV-2 in patients with cervical cancer and also healthy people with sensitive and quantitative Taq Man real-time PCR assay. Materials and methods: Seventy six formaldehyde fixed paraffin embedded tissue specimens from patients with histologically proven history of cervical cancer as well as 150 control blocks were sectioned for deparaffinization and DNA extraction. Results: There was no HSV-2 DNA in our patient specimens but four control samples were positive, all with a history of hysterectomy. Conclusion: Considering the absence of any positive viral HSV-2 DNA in our patients and also the presence of four positive specimens among our controls, we did not find any relationship between the presence of HSV-2 DNA and cervical cancer.

Direct Microwave Sintering of Poorly Coupled Ceramics in Electrochemical Devices

Amiri, Taghi,Etsell, Thomas H.,Sarkar, Partha The Korean Electrochemical Society 2022 Journal of electrochemical science and technology Vol.13 No.3

The use of microwaves as the energy source for synthesis and sintering of ceramics offers substantial advantages compared to conventional gas-fired and electric resistance furnaces. Benefits include much shorter processing times and reaching the sintering temperature more quickly, resulting in superior final product quality. Most oxide ceramics poorly interact with microwave irradiation at low temperatures; thus, a more complex setup including a susceptor is needed, which makes the whole process very complicated. This investigation pursued a new approach, which enabled us to use microwave irradiation directly in poorly coupled oxides. In many solid-state electrochemical devices, the support is either metal or can be reduced to metal. Metal powders in the support can act as an internal susceptor and heat the entire cell. Then sufficient interaction of microwave irradiation and ceramic material can occur as the sample temperature increases. This microwave heating and exothermic reaction of oxidation of the support can sinter the ceramic very efficiently without any external susceptor. In this study, yttria stabilized zirconia (YSZ) and a Ni-YSZ cermet support were used as an example. The cermet was used as the support, and a YSZ electrolyte was coated and sintered directly using microwave irradiation without the use of any susceptor. The results were compared to a similar cell prepared using a conventional electric furnace. The leakage test and full cell power measurement results revealed a fully leak-free electrolyte. Scanning electron microscopy and density measurements show that microwave sintered samples have lower open porosity in the electrode support than conventional heat treatment. This technique offers an efficient way to directly use microwave irradiation to sinter thin film ceramics without a susceptor.

Lack of Association between Chlamydia trachomatis Infection and Cervical Cancer - Taq Man Realtime PCR Assay Findings

Farivar, Taghi Naserpour,Johari, Pouran Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

Background: Cervical cancer is one of the most common cancers in developing countries and the second most common type of cancer in women globally. Several recent studies suggested a co factor role for Chlamydia trachomatis in pathogenesis of cervical cancer. This study aimed to evaluate existence of C. trachomatis DNA in pathologic blocks of patients with cervical cancer. Materials and methods: Seventy-six formaldehyde fixed paraffin embedded tissue specimens from patients with histologically proven history of cervical cancer as well as 150 blocks from healthy peoples were included in the present study. Thin slices were prepared from selected blocks followed by deparaffinization and DNA extraction; the presence of C. trachomatis DNA was examined by Taq Man real-time PCR. Results: Our TaqMan real time PCR assay with cervical specimens of patients with cervical cancer showed that there was no C. trachomatis DNA. Also, we found three positive specimens among our control group. Conclusion: It seems that based on results obtained from the specimens examined in the present study, there is no association between the presence of C. trachomatis DNA in cervical specimens and cervical cancer.