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소아에서 편도절제술 시행시 진통효과 : Tramadol과 Meperidine의 비교
소금영,식홍림,임시경,안태훈,임태승 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.3
Background: Pain is major problem regarding quality of life in children undergoing tonsillectomy. Preemptive analgesia by medicine given before commencement of surgery is a new recommended for relief of pain during and after operation. We compared intra-and postoperative analgesic and recovery characteristics of tramadol, meperidine given at induction of anesthesia in 40 ASA I or II children undergoing tonsillectomy with or without adenoidectomy. Materias and Methods: Fourty children aged 4-7 years undergoing tonsillectomy with or without adenoidectomy were randomly assigned to receive either tramadol 2 mg/kg (group 1) or meperidine 1 mg/kg (group 2) at induction of anesthesia. Thiopental sodium (5 mg/kg) and rocuronium (0.6 mg/kg) were used for the induction of anesthesia, and it was maintained with sevoflurane in N₂O/O₂50/50 via an endotracheal tube. Pain assessment was done by facial pain scale. Agitation scores, time to recovery of spontaneous respiration and the incidence of postoperative nausea and vomiting. Heart rate and mean arterial pressure was recorded at regular intervals. Results: Facial pain scale scores were increased in group 1 at 10 and 20 min in recovery room. There was no difference for agitation scores in the two groups. Intraoperative mean arterial pressure (15th min) were found to be higher in group 1. The time to recovery of spontaneous respiration was delayed with group 2 compared with group 1. The incidence of nausea and vomiting was not statistically differed between groups. Conclusions: Meperidine was more effective for pain relief than tramadol after tonsillectomy in children.
鄭潾相,河泰琪,李淳麟 慶北大學校 産業開發硏究所 1985 硏究報告 Vol.13 No.-
Grain boundaries in policrystalline alloys play an important role on the deformation and its strength. It is necessary that a complete understanding of the effect of grain boundary on the deformation, in order to put these alloys into the best utilization. The purpose of this study is to investigate the effects of grain boundaries on the deformation of (α+β) two phase brass polycrystalline. For this study, grains of specimens were coarsened to simplify the complicate grain boundary. After tensile deformation, slip line analysis near grain boundary was accomplished. Schmid factor, stress delivering factor and strain incompatibility were introduced in the explanation of present results. The activation of slip system which was affected by the grain boundary itself were explained by the combination of these factors. Also, it was introduced that the properties of strain incompatibility depend on the condition of grain boundaries and tensile axis.
위선암에서 Compylobacter Pylori의 발견율
김의한,최득린,정태은 순천향대학교 1993 논문집 Vol.16 No.2
A close relationship between Campylobactor Pylori and gastric disease was reemphasized by many authors. Campylobactor was mainly observed in the antrum of the gastric mucosa, and considered as a cause of gastric ulcer following to gastritis or intestinal metaplasia. This study was carried out to observe the incidence of C.Pylori in the gastric carcinoma diagnosed by endoscopic biopsy. The following results were obtained. 1. Campylobactor pylori was identified in 61 cases(68.5%) of gastric carcinoma among 89 cases of gastric carcinoma. 2. C.Pylori was identified in 35 cases of carcinoma with intestinal metaplasia and 26 cases of that without intestinal metaplasia, indicating no difference between two groups. 3. C.Pylori was equally identified in well differentiated, moderately differentiated and poorly differentiated carcinoma. 4. C.Pylori was more frequently identified in carcinoma of antrum and pylori than that of body. The above result indicate that C.pylori may play a part of roll for the carcinogenesis of the gastric carcinoma following gastritis intestinal metaplasia and gastric ulcer
Cellulases of trichoderma viride ( 2 ) : Induction of Cellulases by Avicel and Their Mode of Action
Tae Lin Huh,Eun Kyong Song,Se Young Lee 생화학분자생물학회 1981 BMB Reports Vol.14 No.4
In order to investigate the characteristics of cellulases induced by Avicel, Trichoderma viride QM 1414 was cultured on Avicel. The culture filtrates were concentrated by (NH₄)₂SO, fractionation and used as enzyme sources, The enzyme preparations were further purified by gel filtration and DEAE-cellulose chromatogaphy and assayed for cotton activity, CMC activity and β-glucosidase activity. The following results were obtained 1. The optimum pH of the cotton activity and CMC activity was between pH 4.8∼ 2. The optimum temperature of cotton activity was 50℃ and of CMC activity 55℃. 5.2. 3. Cellulases induced by Avicel contained low β-glucosidase activity induced by CMC and cellobiose. 4. Cellulase induced by Avicel contained high cotton activity compared with cellulase induced by CMC and cellobiose, 5. A low molecular weight CMCase activity was separated from the rest by Bio Gel P-150 column chromatography. From these, a cellulase that could only degrade CMC woas obtained. The remaining CMCase activity and cotton activity were separated by DEAE-cellulose chromatography, 6. Trichoderma cellulases induced by Avicel could hydrolyze cotton and CMC into glucose in the absence of β-glucosidase.
( Tae Woong Kong ),( In Tae Kim ),( Tridib Kumar Sinha ),( Junho Moon ),( Dong Ho Kim ),( Inseon Kim ),( Kwangyong Na ),( Min-woo Kim ),( Hye-lin Kim ),( Taegyeong Hyeong ),( Jeong Seok Oh ) 한국고무학회 2020 엘라스토머 및 콤포지트 Vol.55 No.4
Stearic acid (SA), polyethylene glycol (PEG), and malic acid (MA) have been used to modify the surface of waste gypsum to develop corresponding poly (butylene adipate-co-terephthalate) (PBAT) composites. According to the mechanical properties, MA-treated gypsum (MA-gypsum) showed the best performance, whereas SA-gypsum showed the worst performance. In contrast to SA and PEG (having -COOH and -OH as polar functional groups, respectively), the presence of both -OH and -COOH in MA is responsible for the superior surface treatment of gypsum and its better dispersion in the polymer matrix (as revealed by FE-SEM analyses). The presence of long aliphatic chain in SA is supposed to inhibit the dispersion of SA-gypsum. Further, the performance of MA-gypsum/PBAT was enhanced by adding polylactic acid (PLA). The maximum optimized contents of MA-gypsum and PLA are 20 and 7.5 wt% for developing a high-performance PBAT composite.
Huh, Tae-Lin,Koh, Suk-Hoon,Lee, Se-Yong The Korean Society for Microbiology and Biotechnol 1985 한국미생물·생명공학회지 Vol.13 No.4
Plasmid pBR322와 runaway Plasmid pSY343을 vector로 사용하여 E. stearothermophilus IAM 11062내의 $\alpha$-amylase 유전자를 E. coli내에 클로닝 하였다. 이때 얻어진 $\alpha$-amylase유전자는 제한효소 Hind III의 말단을 갖고 있는 4.7kb의 크기였으며 E. coli내에서 이들 유전자는 비교적 안정적 있게 유지되고 발현되었다. 재조합 $\alpha$-amylase유전자가 클로닝된 E. coli는 B. stearothermophilus IAM 11062보다 3배의 $\alpha$-amylase를 더 많이 생성하였다. EDTA를 사용한 osmotic shock 방법에 의하여 E. coli내에서 생성된 $\alpha$-amylase는 그 효소 생성량의 75%정도가 periplasm에 존재함이 밝혀졌다. 재조합된 $\alpha$-amylase 유전자에 의해서 E. coli에서 생성된 $\alpha$-amylase는 최적 작용온도가 55$^{\circ}C$로서 이들의 열안정성과 분자량(61,000)도 B. stearothermophilus IAM 11062의 $\alpha$-amylase와 거의 동일하게 나타나 E. coli와 B. stearothermophilus IAM 11062에서 생성된 $\alpha$-amylase는 효소학적 성질이 같음을 보여주었다. A 4.7 kb Hind III fragment containing $\alpha$-amylase gene of Bacillus stearothermophilus IAM 11062 was cloned in Escherichia coil HB101, using plasmid pBR322 and runaway plasmid pSY343 as a vector. The cloned gene was stably maintained and expressed In E.coli. The constructed strain of E. coli have at least 3 times higher amylase activity than the donor strain, of B. stearothermophilus. About 75% of the $\alpha$-amylase produced by the constructed strain of E. coli was localized in the periplasm and it was found that the enzymes can be released by an osmotic shock using EDTA. The enzymatic properties of L-amylase produced in E. coli were very similar to those produced by B. stearothermophilus in terms of optimum temperature, heat stability and molecular weight.