http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Tae-Kook Kim (검색결과 1,271 건)
- 무료
- 기관 내 무료
- 유료
-
-
-
비만 여성을 대상으로 한 해조류 추출물의 국부처치와 운동 병행을 통한 지방분해 효과의 임상적 검정
서태수,이인숙,변재철,김규호,박승한,김유영,김상국,김현정,김상기,신동철,성미영,박종석,김종기,박언휘 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3
This study was carried out to test the body fat breakdown during topical seaweed extract treatment and in combination with the aerobic exercise. Of 20 female obesity subjects, ten treated a cream types of seaweed extract(control group) and ten treated a placebo cream(placebo group). Topical treatment of each sample was designed for 4 weeks, and treated with 2 times a day about 10ml on the abdomen and the thigh, respectively. All subjects were participated aerobic dance half hour a day and four times a week. After 4 weeks of topical treatment and exercise, they were measured body fat, skinfold thickness, body circumference. Then venous blood samples were taken and analyzed blood cells, serum enzymes, and serum lipids. There were reduction of body weight, % of body fat, antebrachium, brachium, chest, waist, thigh circumference and abdomen thickness between pre and post treatment in both group. Especially, body weight and % of body fat significantly reduced in the subjects treating the seaweed extract than those treating the placebo. There were significant decrement in total cholesterol and LDL whereas increment in HDL and TBIL in the control group, but no significant difference in the placebo group. In conclusion, there were 7.6% of body fat reduction during 4 weeks of aerobic exercise and 21% of body fat reducement in combination of topical seaweed treatment and exercise, respectively. These results suggest that the topical treatment of seaweed extract should be very effective for fat breakdown. Especially, the body fat breakdown maximized in the combination with the topical seaweed extracts treatment and the aerobic exercise.
-
이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1
연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.
-
치과용 저금계 합금의 조성 및 열처리에 따른 경도 및 변색에 관한 연구
김철위,김명국,백기석,이용근,윤태호 대한치과기재학회 2000 대한치과재료학회지 Vol.27 No.1
Discoloration of dental alloys results from several reasons such as chemical tarnish, precipitation of chromatic substance on the alloy surface. In this study, the discoloration of 20 kinds of dental casting alloys was measured after immersion in various solutions, and the results were analyzed by the composition of the alloys and solutions. The effects of constitutional elements of the alloys on the color and discoloration of alloys were evaluated also. Cast specimens were polished with #400 silicons carbide paper, and were washed and dried. Vickers hardness of the alloys specimens was measured before and after heat treatment. Color of specimens was measured with the Spectrophotometer (Minolta CM-3500d, Japan.) with the CIELAB scale. Illumination C was used with SCE. Five kinds of aqueous solutions of HP (10% H₂O₂), NS (5% Na₂S), NC (5% NaCL), AS (mucin-added artificial saliva) and SF (10% SnF₂) were used, and the specimens were immersed at 37℃ for one and three days. ΔE* of the mostly discolored alloy for three days in HP was very high as 26.6, 10.27 in NS, 7.88 in AS, 4.23 in SF, and 4.18 in NC. Multiple regression analysis among CIE L*, a*, b* before immersion and the alloy composition showed that each CIE L*, a*, b* was negatively correlated with palladium content, and R value was -0.623, -0.365, -0.674 respectively. Multiple regression analysis among ΔE*, ΔL*, Δa*, and Δb* after there days and the alloy composition showed that silver was positively correlated with ΔE* (R = 0.510, p<0.01), and CIE L* was influenced by silver and copper content, CIE a* was influenced by copper and indium content, CIE b* was influenced by silver content (p<0.01). VHN number was 146.00∼347.60 before heat treatment, and 161.20∼331.20 after heat treatment.
-
腎細胞癌 細胞核 영상의 등급별 분류를 위한 3차원 텍스쳐 定量化 연구
김태윤,최현주,최흥국 仁濟大學校 2006 仁濟論叢 Vol.21 No.1
세포 영상 분석에 널리 사용되는 형태학적이나 위상학적인 정보뿐만 아니라 세포핵과 염색질의 텍스쳐 특정값들은 병리 진단이나 예후 추정을 위한 중요한 정보들을 담고 있다. 이에 따라, 본 논문은 디지털 세포측정학을 기반으로 신장 세포암 (RCC:Renal Cell Carcinoma)의 컨포컬 레이져 스캐닝 현미경 영상에 적용할 수 있는 등급별 분류 시스템 개발을 위한 3차원 텍스쳐 특성값에 대한 연구를 목적으로 한다. 본 연구를 위해 실제 세포핵 데이터로부터 3D GLCM과 3D GLRLM을 정의하고 값을 추출하여 정량적인 분석을 수행하였다. 또한 통계학적인 처리를 통해 6개의 분류 모델을 생성하고 비교하여 그 유효성을 평가하였다. 본 연구의 결과를 통해 현재 널리 이용되고 있는 2차원 기반 영상 분석의 한계를 극복하고 보다 정확한 진단과 예후 추정으로 높은 임상 활용도를 제공할 수 있는 3차원 기반의 새로운 등급 시스템 개발의 기반을 마련하고자 한다. The objective of the this thesis is to study of three-dimensional textural features applied to laser scanning confocal microscopy based on the Digital Image Cytometry. For this study, first, we performed a visualization of cell nuclei using three-dimensional surface rendering and labelling. Then, we also extracted texture feature values from three-dimensional co-occurrence matrices and run-length matrices and performed quantitative analysis using statistics. Finally we tested new classification model based on three-dimensional texture features and performed the comparative study using 5 classification model for validation. Through the result of this study, we could be develop a new grading system of the renal cell carcinoma which have higher clinical usability.
-
김태영,한상국 연세대학교 산업기술연구소 2000 논문집 Vol.32 No.1
XGM based tunable wavelength converter using multi-frequency laser is proposed and the performance of proposed tunable wavelength converter is shown by experiment. Only when MFL operate near threshold, XGM can be observed. For better operation of wavelength converter, peak gain wavelength of modulation SOA in MFL should be around 1550nm and modulation SOA have a low polarization sensitivity and reflectivity of MFL output port should be low.
-
김법완,권태균,노기석,정성광,장세국,정운복,김정완 경북대학교 병원 1997 경북대학교병원의학연구소논문집 Vol.1 No.1
The objective of this study was to characterise the pattern of p53 mutations in bladder turmor. In this study, 25 bladder transitional cell carcinomas were analyed by immunohistochemistry (IHC) for p53 nuclear overexpression, and the results were compared with those of polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) analysis in exon 5-8 of the p53 gene and DNA sequencing analysis. 15 out of 20 cases (75%) showed p53 nuclear immunoreactivities on IHC. On PCR-SSCP analysis, 10 out of 25 cases(40%) had abnormal shifts on mobility. 62% of the mutations were in exon 8. Direct DNA sequencing analysis were performed in these 10 cases to confirm the presence of mutated p53 genes and to determine the type of mutations. Sixteen point mutations were detected in 10 cases. Tow specimens had double mutations and another two had triple mutations. G:C→A:T transitions were the most frequent patterns (62.5%). One mutation was a premature stop codon and two were silent mutations. There out of 10 had a point mutation at codon 285 (GAG/Glu→AAG/Lys) and two had at codon 280(GAG/Glu→AAG/Lys). One of 16 mutations was transition at hot spot codon 273 with CpG site. These results suggest that altered expressions and point mutations of p53 occured in all grade of bladder cancer, but are more associated with hight grade bladder tumors. To elucidate the carcinogenesis of bladder cancer, further studies should be carried out.
-
경구개법 또는 내시경하 비내 접근법으로 치료한 비인강 혈관 섬유종 3예
김진국,이민우,강성호,남태욱,김재영 건국대학교 의과학연구소 2001 건국의과학학술지 Vol.11 No.-
Nasopharyngeal angiofibroma is uncommon, histologically benign vascular tumor that occurs almost exclusively in adolescent males. It is clinically malignant because it has propensity for locally destructive growth and fatal hemorrhage. Treatment of angiofibroma is controversial. The two major treatment modality are surgery and radiation. Adjuvant treatment with chemotherapy or embolization can be used as well. We experienced three cases of nasopharyngeal angiofibroma that was resected by transpalatine and endoscopic endonasal approach with good result. So, we report these with review of literature.
-
김진국,남태욱,임채형,장현종 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-
Background and Objectives: Rhinosinusitis is the most common cause of olfactory impairment and endoscopic sinus surgery is considered as a surgical procedure of choice for treating chronic sinusitis. CC-SIT (Cross-Cultural Smell Identification Test) consists of 12 items well known in most non-English-speaking cultures. Authors evaluated the therapeutic effects of endoscopic sinus surgery on olfactory dysfuction using CC-SIT. Materials and Methods: The subjects of this study were seventeen sinusitis patient who had undergone ESS from November 2001 through April 2002. All patients were divided into two groups according to nasal polyp and CT findings. CC-SIT was used for the evaluation of olfactory function. Results: Forty seven percents of patients had improvement in olfactory function postoperatively. No correlation was found between changes in CC-SIT score and nasal polyp and preoperative CT findings. Conclusion: It is concluded that nasal polyp and CT findings have no effect on olfaction.
RISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
