家免를 利用한 PYROST®(Porous Hydroxyapatite)의 骨再生에 關한 實驗的 硏究

崔應鈺,金泰淵,丁銓殷 고려대학교 의과대학 1989 고려대 의대 잡지 Vol.26 No.1

PYROST® is a biocompatible porous matrix implantable as a bone graft substitute. This biomaterial has been used in a variety of experimental settings over the past years and more recently has been used in clinical applications for the filling of bone defects. Its use in human may help to eleminate the morbidity of autogenous bone graft donor sites and resorption of autogenous bone graft. We studied the new bone regeneration within a PYROST® block which were placed end to end in a subperiosteal pocket on the nasal dorsum of 1.8-2.0 ㎏ New Zealand white rabbit. En block specimen were harvested at 4, 8 and 12 weeks post onlay. These were then decalclfied, imbedded and sectioned in the sagittal plane. For the confirmation of bone regeneration within a PYROST® we used weighing the PYROST and light microscope. point-counting technique and fluorescent microscope. The results obtained were summarized as follow: 1. There was no volume change of PYROST® 2. The activation of osteoblasts and bone matrix were found at 4 weeks and matrix of lamellar pattern was found 12 weeks post onlay. 3. The quantity of the regenerated new bone within a PYROST® was increased at 12 weeks(3.2±2.1%) than 4 weeks(1.5± 1.8%).

대전광역시 상수도 원단위 조사 및 장래 용수수요량 예측

김태응,임봉수,허재영,이길영 大田大學校 環境問題硏究所 1999 환경문제연구소 논문집 Vol.4 No.-

This study was carried out examine per capita demand and forecast water demand until 2031 in Taejon City. These data can be used as the basis for the desgn and maintenance of water supply system. Future water demand including industrial water supply in Taejon City was predicted about 1,488,000m3/day in 2011, about 1,876,000 m3/day in 2021, about 2,275,000m3/day in 2031.

日常生活의 身體活動量 硏究에 있어서 步數計의 活用 : 運動量 指標로서의 妥當性 Ⅱ. Validity with means of an lndex of ergometry

孫泰烈,安應男 成均館大學校 科學技術硏究所 1986 論文集 Vol.37 No.2

In 28.51±5.0 year old male adults(n = 6) actual Step rate, HR, and estimated value of VO_2 on a treadmill was compared to the scores of 6 types of mechanical pedometer attached to waist belt. In walking and running at each speed all types pedometer give on overstimation of Ca. 7∼30 step/min. There was a linear relationship between pedometer Reading Score and Heart Rate. If Pedometers register only during from 6 km/h walking to 15 km/h running they reflect actual steprate fair good and give a good estimation of the change in Oxygen Uptake and an index of Energy Expenditure as work load gathers.

흰쥐에서 탄수화물 종류가 운동시 당 및 지질대사에 미치는 영향

권태동,전중기,민경선,김형렬,장응찬 대구대학교 기초과학연구소 1998 基礎科學硏究 Vol.15 No.2

The purpose of this study was to investigate the effects of glucose, sucrose, and glucose polymer(GP) ingestion on the carbohydrate and lipid metabolism during treadmill running in rats. Rats were randomly assigned to normal, control and carbohydrate groups. Carbohydrate group was divided into glucose, sucrose and GP ingested rats. The experiment was carried out after overnight fasting. Rats were administrated either normal saline(control) or carbohydrates solutions of formulated glucose(6%), sucrose(6%) and GP(6%) via polyethlene tube to stomach before treadmill run. Exercise was loaded by a treadmill run at the speed of 1 km/hour for 30, 60 and 120 minutes. The results of experiment were as follows: Plasma glucose levels were decreased in proportion to the exercise time in control, but increased at treadmill run 30 minutes and then gradually decreased with the lapse of the exercise time in carbohydrates compared with normal rats. It decreased in control, glucose, sucrose and GP compared with normal rats in decreasing order at treadmill run 120 minutes(% change of plasma glucose level of control, glucose, sucrose and GP compared with normal rats were 67, 74, 87 and 91 in plasma glucose level at treadmill run 120 min., respectively). Plasma lactate levels were increased by the exercise loading compared with normal in control and carbohydrates ingested rats. It increased in control, sucrose and GP in increasing order compared with normal rats, at treadmill run 120 minutes(% change of plasma lactate level of control, glucose, sucrose and GP compared with normal rats were 167, 185, 149 and 114 in plasma lactate level at treadmill run 120 min., respectively). Plasma FFA levels had tendency to increase by the exercise loading compared with normal in control and carbohydrates ingested rats. It showed increase in the sucrose, glucose, GP and control rats in Increasing order compared with normal rats at treadmill run 120 minutes(% change of plasma FFA level of control, glucose, sucrose and GP compared with normal rats were 151, 153, 166 and 152 in plasma FFA level at treadmill run 120 min., respectively). Plasma acetoacetate levels were higher in control compared with carbohydrates ingested rats at treadmill run 30, 60 and 120 minutes. Plasma beta-hydroxybutyrate levels increased by exercise compared with normal rats in control and carbohydrates ingested rats at treadmill run 30, 60, 120 minutes. Plasma insulin levels were decreased in proportion to the exercise time in control compared with normal rats, but in carbohydrates ingested rats increased at treadmill run 30 minutes and then gradually deceased with the lapse of the exercise time compared with normal. In carbohydrates ingested rats, plasma insulin levies were higher than control. Hematocrit did not show any difference between control and carbohydrates rats at treadmill run 30, 60 and 120 minutes. From these experimental results, it is suggested that the exhaustion of skeletal muscle glycogen, the hypoglycemia, the overproduction of lactate and dehydration is delayed in carbohydrates ingested rats. GP of the carbohydrates is considered as the most effective for these effects. Therefore, intake of carbohydrates before exercise, especially GP seems to increase performance in the prolonged moderate exercise.

고상반응법에 의해 제조된 Zn_2SiO_4:Mn 녹색 형광체의 발광 특성

박응석,장호정,허경무,조태환 단국대학교 신소재기술연구소 1997 신소재 Vol.7 No.-

MnO_2와 MNCO_3를 활성체로 사용하여 Zn_2SiO_4: Mn 녹색 형광체를 고상반응법에 의해 제조하고, 이들 시료에 대해 소결온도, 활성제 종류 및 농도에 따른 발광 특성 및 결정성 등을 조사 하였다. MnCO_3를 활성제로 사용한 형광체 시료의 경우, Mn의 도핑농도를 X=0.08(Zm_2-xMn_xSiO_4)로 첨가하여 1300℃에서 4시간 질소분위기에서 소결한 형광체 시료에서 최대 발광휘도 와 양호한 색순도를 나타내었다. 활성제로 MnO_2를 사용한 경우가 MnCO_3를 첨가한 경우보다 발광 스펙트럼강도가 떨어지는 경향을 보여 주었으며, 이 결과는 MnO_2 활성제의 경우 Mn의 부적절한 원자가에 기인하는 것으로 판단된다. SEM 관찰결과 형광체 분말의 입도 크기는 약 3∼6 ㎛를 나타내었다. We have prepared a good quality Zn_2SiO_4: Mn green phosphors using MnO_2 and MnCO_3 as activators by the solid state reaction method. The luminance properties and crystalline qualities were investigated as functions of the firing temperature and activator concentrations. In Zn_20xMn_2SiO_4, the phosphors doped with MnCO_3, Mn concentration of X=0.08 showed the highest intensity of emission spectra and good color purity at the firing temperature of 1300℃ for 4hrs under N_2 atmospher. At the same concentration and firing condition, the emission spectrum peaks of the phosphors doped with MnO_2 were lower than those of samples doped with MnCO_3. This may be due to the improper valence state of Mn cation. As Mn contents increased, the maximum of emission spectra shifted slightly toward higher wavelength. From the SEM micrograph, it was found that the phosphors were composed of small grains about 3∼6㎛.

人工衛星 데이터를 이용한 솔잎혹파리와 산성우의 상관관계 분석

金應南,後薦惠之後薦惠之端,楊寅台 江原大學校 附設 環境硏究所 1998 環境硏究 Vol.15 No.-

솔잎혹파리에 의한 송림피해는 그 대상지역이 매우 넓고 지속적으로 증가하면서 위치를 옮겨가고 있다. 또한 송림피해는 약 7년이 경과하면 회복되는 것으로 보고되고 있으나 일부지역에서는 그대로 고사하고회생하지 못하고 있는데 이것은 산성우와 밀접한 관계가 있는 것으로 추측된다. 따라서 이 연구에서는1990년대에 들어서 강원도 지역 중에서도 송림고사 피해가 가장 심하게 발생 하고 있는 평창권을 대상으로 하여, 1984년과 1993년의 인공위성자료로부터 식물의 활 In this study, an attempt was done to analyze the damaged areas by pine gall midge in PYONGCHANG county by using the LANDSAT/TM data observed on Nov.12, 1984 and Oct.20. 1993. This county has suffered most serious damage in the forest areas caused by pine gall midge in KANGWON prefecture, KOREA. The method of Normalized Difference Vegetation Index is used to detect the damage situation for the passed 10 years. A normal recovery of the damaged areas was observed 7 years after the first damage has occurred. But, there was a lot of pines died and never resurrect again in some areas. The reason of this phenomenon may due mainly to the acid rain in that areas. Therefore the relationship between the damaged areas and the acid rain is considered in this study. As a result of this study the damage state and the distribution pattern of the damaged areas in PYONGCHANG county are clearly understood. The acid rain (pH less than 5.6)is observed on the whole KANGWON prefecture in the 1990's and also the Rainfall intensity of pH less than 5.0 is increased by 10 times in 1995 compared with rainfall intensity of the same pH observed in 1991

정적 부하의 비대칭적 적용에 따른 등 근육의 근전도 분석

김태영,박은영,이응상 한국전문물리치료학회 1997 한국전문물리치료학회지 Vol.4 No.1

아날로그 동작 펄스 신경회로망의 하드웨어 구현과 그 특성

옥정태,김응수 선문대학교 대학원 1999 대학원학술논문집 Vol.1 No.-

본 연구에서 제안한 전자회로는 신경세포들간의 정보전달을 펄스로, 신경세포내의 정보처리를 아날로그 형태로 구현함으로써 생체에 가까운 방식을 취했다. 시냅스에서는 신경세포로부터의 전압펄스롤 결합하증에 맞추어서 전류치가 다른 전류펄스로 변환한다. 이 전류펄스는 신경세포에 대옹한 콘덴서와 저항에 입력되어 막전위가 되고, 또한 신청세포는 막전위에 대응한 전압펄스를를 출력한다. 집적회로를 설계하기에 앞서 개별소자룰 이용하여 뉴런과 시냅스 회로들 시험제작하였다. 이 시험제작희로는 집접화를 고려하여 되도록 간단한 회로구성올 생각했다. Three different etching solutions KOH, KOH-IPA and TMAH were used for anisotropic etching for membrane structure formation, single crystal silicon substrate. The etching characteristic was observed for the each solution in this experiment. Also, etching rate depends on the etchant temperature and concentration. The different characteristics were observed according to pattern directions and etchant concentration was measured. The pattern was made to incline 45℃ on the primary flat and the KOH 20w t·%, the etching shape was U-groove above 80℃, and V-groove shape was observed below 80℃. The hillock which was generated at silicon surface was decreased as the etchant temperature and concentration increased. In this experiments, the new membrane structure design and process were introduced for MEMS thermocouple.

Filamentous fungi Aspergillus species에서 Phytase 고발현 균주의 선별

이응석,함영태 中央大學校 食糧資源硏究所 1997 食糧資源硏究所 論文集 Vol.18 No.1

Phytase production of Aspergillus species were influenced by nitrogen source. Ammonium ions, especially ammonium phosphate (NH4H2PO4), were markedly superior to nitrate for the Phytase production. For the isolation of phytase gene, the culture of Aspergillus species (A. oryzae) were maintained on PSM media containing ammonium phosphate. After 4 days, mycellia were harvested by centrifugation and isolated total RNA. cDNAs were synthesized from total RNA by RT-PCR. The Phytase gene was amplified with the primers designed from A. ficuum sequence. 1.2 and 2.0 kb of the amplified DNA fragments by secondary PCR and subcloned in pT7Blue-T vector. Aspergillus species (A. oryzae and A. ficuum) were treated with 254㎚ of UV light for the screening of high phytase producing mutant strains, comparative to wild type on PSM media, containing ammonium phosphate. Two UV mutant strains in A. oryzae and three, in A. ficuum were isolated. These mutants are 1.5 to 2.0 times better phytase-production than Wild type.

정신지체아와 학습부진아의 작업기억 특성에 관한 비교연구

여광웅,김나영,정영숙,이태화 한국정신지체아교육학회 2001 지적장애연구 Vol.3 No.-

이 연구는 정신지체아와 학습부진아의 작업기억(working memory) 특성을 비교 분석하여, 그들의 인지능력 즉 정보처리 용량에 관련된 변인과 이에 따른 교수방법을 탐색 논의하였다. 연구결과와 논의를 통해 볼 때, 학습부진아의 작업기억 용량이 정신지체아보다 더 큰 것으로 나타났으며, 모두 지능과 연령 그리고 자극 제시시간변인이 기억탐색 속도, 전략사용, 부호화 등의 다양한 심리적 기제를 통해 작업기억 용량에 영향을 주고 있는 것으로 밝혀졌다. 그리고 정신연령과 자극 제시시간이 증가할수록 작업기억 용량이 증가되는 것으로 나타났으며, 이것은 정신연령과 자극 제시시간이 증가함에 따라 기억 수행에 용이한 심릭적 기제가 활성화 되고 있음을 의미한다. The present study was designed to define the capacity of working memory (WM) of mentally retarded(MR) and Underachiever(UA). Subjects were 30 MR and 30 UA who were the same mental age, sampled from a special classes in the elementary schools and the middle schools in chungnam. Two group was formed according to three mental age (6,8,10) IQ scores ranges 50~75 for MR group, 90~110 for UA group. In order to define the capacity of WM of MR and UA, group(MR, UA), mental age(6,8,10) and speed of task presentation (3", 6")were used as independent variables and the capacity of WM as dependent variables. This study was taken following statistical methods in order to test study problems, problem 1 was conducted three-way analysis of variance by repeated-measures. Turky test was conducted to notice difference according to age. The main conclusion were as follows. First, the capacity of WM of UA is more larger than that of MR. Second, there are significant differences in the capacity of WM of MR according to mental age and speed of task presentation. Again as mental age and speed of task presentation in crease, the capacity of WM of MR increases. Finally, the capacity of WM of UA increases according to mental age and speed of task presentation. Jst as with MR, as mental age and speed of task presentation increase, the capacity of WM of UA increases.