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( Tae Jin Park ),( Jong Yeol Lee ),( Woo Kyun Lee ),( Doo Ahn Kwak ),( Han Bin Kwak ),( Sang Chul Lee ) 대한원격탐사학회 2011 大韓遠隔探査學會誌 Vol.27 No.6
Forests have been considered one of the most important ecosystems on the earth, affecting the lives and environment. The sustainable forest management requires accurate and timely information of forest and tree parameters. Appropriately interpreted remotely sensed imagery can provide quantitative data for deriving forest information temporally and spatially. Especially, analysis of individual tree detection and crown delineation is significant issue, because individual trees are basic units for forest management. Individual trees in aerial imagery have reflectance characteristics according to tree species, crown shape and hierarchical status. This study suggested a method that identified individual trees and delineated crown boundaries through adopting gradient method algorithm to amplified greenness data using red and green band of aerial imagery. The amplification of specific band value improved possibility of detecting individual trees, and gradient method algorithm was performed to apply to identify individual tree tops. Additionally, tree crown boundaries were explored using spectral intensity pattern created by geometric characteristic of tree crown shape. Finally, accuracy of result derived from this method was evaluated by comparing with the reference data about individual tree location, number and crown boundary acquired by visual interpretation. The accuracy (K) of suggested method to identify individual trees was 0.89 and adequate window size for delineating crown boundaries was 19×19 window size (maximum crown size: 9.4m) with accuracy (K) at 0.80.
Maximum Canopy Height Estimation Using ICESat GLAS Laser Altimetry
( Tae Jin Park ),( Woo Kyun Lee ),( Jong Yeol Lee ),( Masato Hayashi ),( Yan Hong Tang ),( Doo Ahn Kwak ),( Han Bin Kwak ),( Moon Il Kim ),( Gui Shan Cui ),( Ki Jun Nam ) 대한원격탐사학회 2012 大韓遠隔探査學會誌 Vol.28 No.3
To understand forest structures, the Geoscience Laser Altimeter System (GLAS) instrument have been employed to measure and monitor forest canopy with feasibility of acquiring three dimensional canopy structure information. This study tried to examine the potential of GLAS dataset in measuring forest canopy structures, particularly maximum canopy height estimation. To estimate maximum canopy height using feasible GLAS dataset, we simply used difference between signal start and ground peak derived from Gaussian decomposition method. After estimation procedure, maximum canopy height was derived from airborne Light Detection and Ranging (LiDAR) data and it was applied to evaluate the accuracy of that of GLAS estimation. In addition, several influences, such as topographical and biophysical factors, were analyzed and discussed to explain error sources of direct maximum canopy height estimation using GLAS data. In the result of estimation using direct method, a root mean square error (RMSE) was estimated at 8.15 m. The estimation tended to be overestimated when comparing to derivations of airborne LiDAR. According to the result of error occurrences analysis, we need to consider these error sources, particularly terrain slope within GLAS footprint, and to apply statistical regression approach based on various parameters from a Gaussian decomposition for accurate and reliable maximum canopy height estimation.
Ahn Ga Young,Koo Bon San,Joo Kyung Bin,Kim Tae Hwan,Lee Seunghun 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.10
Objective: We quantitatively measured the fat fraction (FF) in the vertebrae of patients with ankylosing spondylitis (AS) using magnetic resonance imaging (MRI) and investigated the role of FF as an indicator of both active inflammation and chronicity. Materials and Methods: A total of 52 patients with AS who underwent spinal MRI were retrospectively evaluated. The FF values of the anterosuperior and anteroinferior corners of the bone marrow in the L1–S1 spine were assessed using the modified Dixon technique. AS activity was measured using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), AS Disease Activity Score (ASDAS), and serum inflammatory marker levels. AS disease chronicity was assessed by AS disease duration and the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS). Univariable and multivariable regression analyses were conducted to investigate the correlation between FF and other clinical characteristics. Results: The mean FF ± standard deviation of the total lumbar spine was 43.0% ± 11.3%. At univariable analysis, spinal FF showed significant negative correlation with BASDAI (β = -0.474, p = 0.002) and ASDAS with C-reactive protein (ASDAS-CRP; β = -0.478, p = 0.002) and a significant positive correlation with AS disease duration (β = 0.440, p = 0.001). After adjusting for patient age, sex, and total mSASSS score, spinal FF remained significantly negatively correlated with BASDAI (β = -0.543, p < 0.001), ASDAS-CRP (β = -0.568, p < 0.001), and ASDAS with erythrocyte sedimentation rate (β = -0.533, p = 0.001). Spinal FF was significantly lower in patients with very high disease activity (ASDAS-CRP > 3.5) than in those with only high disease activity (2.1 ≤ ASDAS-CRP ≤ 3.5) (p = 0.010). Conclusion: Spinal FF may help assess both AS disease activity and chronicity.
Angiotensin II Modulates p130Cas of Podocytes by the Suppression of AMP-Activated Protein Kinase
Ha, Tae-Sun,Park, Hye-Young,Seong, Su-Bin,Ahn, Hee-Yul The Korean Academy of Medical Sciences 2016 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.31 No.4
<P>Angiotensin II (Ang II) induces the pathological process of vascular structures, including renal glomeruli by hemodynamic and nonhemodynamic direct effects. In kidneys, Ang II plays an important role in the development of proteinuria by the modification of podocyte molecules. We have previously found that Ang II suppressed podocyte AMP-activated protein kinase (AMPK) via Ang II type 1 receptor and MAPK signaling pathway. In the present study, we investigated the roles of AMPK on the changes of p130Cas of podocyte by Ang II. We cultured mouse podocytes and treated them with various concentrations of Ang II and AMPK-modulating agents and analyzed the changes of p130Cas by confocal imaging and western blotting. In immunofluorescence study, Ang II decreased the intensity of p130Cas and changed its localization from peripheral cytoplasm into peri-nuclear areas in a concentrated pattern in podocytes. Ang II also reduced the amount of p130Cas in time and dose-sensitive manners. AMPK activators, metformin and AICAR, restored the suppressed and mal-localized p130Cas significantly, whereas, compound C, an AMPK inhibitor, further aggravated the changes of p130Cas. Losartan, an Ang II type 1 receptor antagonist, recovered the abnormal changes of p130Cas suppressed by Ang II. These results suggest that Ang II induces the relocalization and suppression of podocyte p130Cas by the suppression of AMPK via Ang II type 1 receptor, which would contribute to Ang II-induced podocyte injury.</P>
Yu Bin Seo,Su-Jin Moon,Chan Hong Jeon,Joon Young Song,Yoon-Kyoung Sung,Su Jin Jeong,Ki Tae Kwon,Eu Suk Kim,Jae-Hoon Kim,Hyoun-Ah Kim,Dong-Jin Park,Sung-Hoon Park,Jin Kyun Park,Joong Kyong Ahn,Ji Seon 대한류마티스학회 2020 대한류마티스학회지 Vol.27 No.3
To develop a clinical practice guideline for vaccination in patients with autoimmune inflammatory rheumatic disease (AIIRD), the Korean College of Rheumatology and the Korean Society of Infectious Diseases developed a clinical practice guideline according to the clinical practice guideline development manual. Since vaccination is unlikely to cause AIIRD or worsen disease activities, required vaccinations are recommended. Once patients are diagnosed with AIIRD, treatment strategies should be established and, at the same time, monitor their vaccination history. It is recommended to administer vaccines when the disease enters the stabilized stage. Administering live attenuated vaccines in patients with AIIRD who are taking immunosuppressants should be avoided. Vaccination should be considered in patients with AIIRD, prior to initiating immunosuppressants. It is recommended to administer influenza, Streptococcus pneumoniae, hepatitis A, hepatitis B, herpes zoster, measles-mumps-rubella virus, human papillomavirus, and tetanus-diphtheria-pertussis vaccines in patients with AIIRD; such patients who planned to travel are generally recommended to be vaccinated at the recommended vaccine level of healthy adults. Those who live in a household with patients with AIIRD and their caregivers should also be vaccinated at levels that are generally recommended for healthy adults.