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Sylvia Oghogho Omage,Noghayin E.J. Orhue,Kingsley Omage 한국식품영양과학회 2022 Preventive Nutrition and Food Science Vol.27 No.1
The effectiveness of Dennettia tripetala extracts was compared to that of the standard drug, silymarin, in reducing chronic liver and kidney anomalies. Male albino Wistar rats were grouped in tens. Carbon tetrachloride was dissolved in olive oil (1:4) and administered to specific groups at a dose of 3 mL/kg body weight (bw) twice a week for six weeks. From week five, the extracts and silymarin were administered in distilled water daily for two weeks at doses of 250 mg/kg bw and 6 mg/kg bw, respectively, to specific groups. All administrations were carried out using a gavage, with appropriate controls. These results showed that the plant extracts decreased the serum activity of liver marker enzymes, restored the liver and serum lipid profiles as well as serum protein profile, reduced serum, urea, and creatinine, and restored superoxide dismutase and catalase activities in the liver and kidneys, which carbon tetrachloride had altered. The extracts also decreased steatosis and centriole congestion in the liver as well as necrosis and structural damage in the kidneys, which carbon tetrachloride caused, and the extracts proved to be as potent as silymarin. The extracts also decreased the expression of fas (P<0.05), sod-1 (P<0.05), and tnf-α (P>0.05) in the liver, which carbon tetrachloride had increased. Conclusively, D. tripetala reduced chronic liver and kidney damage induced by carbon tetrachloride; it reduced the expression of fas, sod-1, and tnf-α in the liver to levels similar to that of the control group, and it was as effective as silymarin.
A Short Test of English Silent Word Reading for English Language Learners
Sylvia C. Kalindi,Catherine Mcbride Chang,Shingfong Chan,Kien Hoa Kevin Chung,Chia Ying Lee,Urs Maurer,Xiuhong Tong 한국아동학회 2015 Child studies in Asia-Pacific context Vol.5 No.2
We developed a test of English silent word reading, following work by Mather, Hammill, Allen, and Roberts (2004) and Bell, McCallum, Krik, Fuller, and McCane-Bowling (2007), in order to tap Hong Kong Chinese children``s reading of English as a foreign language. We created one subtest of individual word reading and another of word reading contextualized within sentences; together, these tests require no more than 10 minutes for administration. In Study 1, we administered the entire test to 552 second grade Hong Kong Chinese children between the ages of 70 and 121 months old, from five different primary schools. The association between the subtests of English silent word reading and contextual reading was positively correlated (.78). In Study 2, 77 Hong Kong Chinese second graders were tested on our newly developed English silent word reading test, together with non-verbal IQ, an English word reading and a Chinese character recognition test (both read aloud). With age and non-verbal IQ statistically controlled, there was a significant correlation between English silent word reading and the more standard English word reading, read aloud, (.78); the association between English silent word reading and Chinese character recognition was also positively correlated (.49). This newly created test is a quick and reliable measure, suitable for both educators and researchers to use to identify poor readers who learn English as a foreign or second language.
Sylvia Chong 한국교육개발원 2011 KEDI Journal of Educational Policy Vol.8 No.2
Research indicates that developing a teacher’s professional identity is both a personal as well as a social process. This study examines teachers’ professional identity development at three time points – at the entry and exit of their one-year teacher preparation program and at the end of their first year as novice teachers. The study aims to establish a baseline understanding of their perceptions about teaching while they embark on the initial teacher preparation program. It explores the changes in their perceptions (if any) at the point of graduation and after their first year of teaching. The implications of the findings are discussed in terms of informing admissions criteria into the programs, how initial teacher preparation programs can be enhanced and key areas of focus for teacher induction programs.
Sylvia Oghogho Omage,Noghayin E. Jerry Orhue,Kingsley Omage 한국식품영양과학회 2021 Preventive Nutrition and Food Science Vol.26 No.2
Dennettia tripetala, better known as ‘pepperfruit’, is a medicinal plant consumed in West Africa. D. tripetala possesses strong antioxidant properties and contains uvariopsine, an alkaloid which improves bile secretion and liver function. In the present study, the ethanolic extract of D. tripetala fruits was tested for its ability to alleviate pathophysiological conditions bordering on oxidative stress, including protein and lipid dyshomeostasis, inflammation, and hepatic and glomerular injury. Male albino Wistar rats were administered carbon tetrachloride twice a week for two weeks, and the ethanolic extract of D. tripetala fruits was administered from days 8∼14. The serum, liver, and kidneys of the rats were then subjected to biochemical assays and imaging. The extract restored the activities of liver marker enzymes in serum and the concentrations of lipids and proteins in both circulation and the liver to normal. The extract also restored the activities of antioxidant enzymes in liver and kidneys, and the concentrations of urea and creatinine in the blood. The extract also repaired the altered structures of the liver and kidney. Overall, D. tripetala elicited strong medicinal effects in rats. This study showed that the fruits of D. tripetala contain substances that could be extracted or synthesized for use in drugs for the treatment of liver and kidney disease.