Hong JeongHa's Tianyuanshu and Zhengcheng Kaifangfa

홍성사,홍영희,김영욱,Hong, Sung Sa,Hong, Young Hee,Kim, Young Wook The Korean Society for History of Mathematics 2014 Journal for history of mathematics Vol.27 No.3

Tianyuanshu and Zengcheng Kaifangfa introduced in the Song-Yuan dynasties and their contribution to the theory of equations are one of the most important achievements in the history of Chinese mathematics. Furthermore, they became the most fundamental subject in the history of East Asian mathematics as well. The operations, or the mathematical structure of polynomials have been overlooked by traditional mathematics books. Investigation of GuIlJib (九一集) of Joseon mathematician Hong JeongHa reveals that Hong's approach to polynomials is highly structural. For the expansion of $\prod_{k=11}^{n}(x+a_k)$, Hong invented a new method which we name Hong JeongHa's synthetic expansion. Using this, he reveals that the processes in Zhengcheng Kaifangfa is not synthetic division but synthetic expansion.

Selective formation of GaN-based nanorod heterostructures on soda-lime glass substrates by a local heating method

Hong, Young Joon,Kim, Yong-Jin,Jeon, Jong-Myeong,Kim, Miyoung,Choi, Jun Hee,Baik, Chan Wook,Kim, Sun Il,Park, Sung Soo,Kim, Jong Min,Yi, Gyu-Chul IOP Pub 2011 Nanotechnology Vol.22 No.20

<P>We report on the fabrication of high-quality GaN on soda-lime glass substrates, heretofore precluded by both the intolerance of soda-lime glass to the high temperatures required for III-nitride growth and the lack of an epitaxial relationship with amorphous glass. The difficulties were circumvented by heteroepitaxial coating of GaN on ZnO nanorods via a local microheating method. Metal-organic chemical vapor deposition of ZnO nanorods and GaN layers using the microheater arrays produced high-quality GaN/ZnO coaxial nanorod heterostructures at only the desired regions on the soda-lime glass substrates. High-resolution transmission electron microscopy examination of the coaxial nanorod heterostructures indicated the formation of an abrupt, semicoherent interface. Photoluminescence and cathodoluminescence spectroscopy was also applied to confirm the high optical quality of the coaxial nanorod heterostructures. Mg-doped GaN/ZnO coaxial nanorod heterostructure arrays, whose GaN shell layers were grown with various different magnesocene flow rates, were further investigated by using photoluminescence spectroscopy for the p-type doping characteristics. The suggested method for fabrication of III-nitrides on glass substrates signifies potentials for low-cost and large-size optoelectronic device applications. </P>

Influence of Collapse and Re-ventilation of Lung on the Development of Pulmonary Edema

Sang Hyun Kwak,Won Jong Jin,Hong Beom Bae,Seong Wook Jeong,Sung Su Chung,Chang Young Jeong Korean Society of Critical Care Medicine 2004 Acute and Critical Care Vol.19 No.1

BACKGROUND: This study was to clarify the influence of collapse and re-ventilation of lung on the development of pulmonary edema in rabbit. METHODS: Animals were randomly assigned to one of three groups: Sham group receiving two lung ventilation (n=14), Collapse group receiving collapse of right lung (n=14), Reventilation group receiving collapse of right lung for 3 hours followed by reventilation of collapsed right lung for 3 hours (n=14). The lung of rabbits were ventilated with 50% oxygen through the tracheostomy. Right main bronchus was secured by thoracotomy in all animal. Collapse and reventilation were performed using by bulldog forcep. Mean arterial pressure, heart rate, arterial oxygen tension (PaO2), peripheral blood leukocyte and platelet counts were recorded at 0, 1, 2, 3, 4, 5 and 6 hour after the start of experiment. The wet to dry (W/D) weight ratio of lung, lung injury score and leukocyte counts, percentage of polymorphonuclear leukocyte (PMNL), concentration of albumin, and interleukin-8 (IL-8) in bronchoalveolar lavage fluid (BALF) were measured 6 hour after the start of experiment in both lung. RESULTS: W/D weight ratio of lung, lung injury score and leukocyte counts, percentage of PMNL, concentration of albumin and IL-8 in BALF were significantly increased in both lung of reventilation group. And the degree of increases is more significant in right than left lung. CONCLUSIONS: These findings suggest that reventilation of collapsed lung causes the bilateral pulmonary edema in rabbit mainly by activating neutrophil and IL-8 responses, which may play a central role in non cardiogenic pulmonary edema.

Effect of Renal Denervation on Suppression of PVC and QT Prolongation in a Porcine Model of Acute Myocardial Infarction

Sung Soo Kim,Hyun Kuk Kim,Hyung Wook Park,Myung Ho Jeong,임경섭,Hae Jin Kee,Yu Hee Ryu,Han Byul Kim,Joo-Young Na,Young-Jae Ki,Keun-Ho Park,Dong-Hyun Choi,Ki Hong Lee,Nam Sik Yoon,Jeong Gwan Cho 대한심장학회 2020 Korean Circulation Journal Vol.50 No.1

Background and Objectives: Antiarrhythmic effect of renal denervation (RDN) after acute myocardial infarction (AMI) remains unclear. The goal of this study was to evaluate the effect of RDN on ventricular arrhythmia (VA) after AMI in a porcine model. Methods: Twenty pigs were randomly divided into 2 groups based on RDN (RDN, n=10; Sham, n=10). After implanting a loop recorder, AMI was induced by occlusion of the middle left anterior descending coronary artery. Catheter-based RDN was performed for each renal artery immediately after creating AMI. Sham procedure used the same method, but a radiofrequency current was not delivered. Electrocardiography was monitored for 1 hour to observe VA. One week later, the animals were euthanized and the loop recorder data were analyzed. Results: Ventricular fibrillation event rate and the interval from AMI creation to first VA in acute phase were not different between the 2 groups. However, the incidence of premature ventricular complex (PVC) was lower in the RDN than in the Sham. Additionally, RDN inhibited prolongation of the corrected QT (QTc) interval after AMI. The frequency of non-sustained or sustained ventricular tachycardia, arrhythmic death was lower in the RDN group in the early period. Conclusions: RDN reduced the incidence of PVC, inhibited prolongation of the QTc interval, and reduced VA in the early period following an AMI. These results suggest that RDN might be a therapeutic option in patients with electrical instability after AMI.

Risk factors for parastomal hernia: based on radiological definition

Sung Yeon Hong,Seung Yeop Oh,Jae Hee Lee,Do Yoon Kim,Kwang Wook Suh 대한외과학회 2013 Annals of Surgical Treatment and Research(ASRT) Vol.84 No.1

Purpose: The aim of this study was to investigate the clinical and radiological incidence of parastomal hernia and to analyze the risk factors for parastomal hernia. Methods: We reviewed retrospectively 108 patients with end colostomy from January 2003 to June 2010. Age, sex, surgical procedure type, body mass index (kg/m2), stoma size, and respiratory comorbidity were documented. Results: There were 61 males (56.5%) and 47 females (43.5%). During an overall median follow-up of 25 months (range, 6 to 73 months), 36 patients (33.3%) developed a radiological parastomal hernia postoperatively and 29 patients (26.9%) presented with a clinical parastomal hernia. In multivariate analysis, gender (odds ratio [OR], 6.087; P = 0.008), age (OR, 1.109; P = 0.009) and aperture size (OR, 6.907; P 〈 0.001) proved to be significant and independent risk factors after logistic regression analysis. Conclusion: This study showed that the incidence of radiological parastomal hernia is higher than clinical parastomal hernia. Risk factors for parastomal hernia proved to be female, age, and aperture size.

Comparison of Therapeutic Efficacy of Gefitinib and Erlotinib in Patients with Squamous Cell Lung Cancer

( Hong Joon Shin ),( Tae Ok Kim ),( Hyun Wook Kang ),( Su Young Chi ),( Hee Jung Ban ),( Soo Ok Kim ),( Yong Soo Kwon ),( In Jae Oh ),( Kyu Sik Kim ),( Yu Il Kim ),( Sung Chul Lim ),( Young Chul Kim ) 대한결핵 및 호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.71 No.1

Background: Gefitinib and erlotinib are useful, molecular targeted agents in patients with non-small-cell lung cancer (NSCLC) who failed previous chemotherapy. We compared the efficacy and toxicity of two drugs in patients with squamous cell lung cancer, most of whom are male smokers. Methods: We retrospectively reviewed the clinical information on patients with NSCLC who were treated with gefitinib or erlotinib treatment at Chonnam National University Hwasun Hospital between July 2002 and November 2009. The overall response rate (ORR), overall survival (OS) and progression-free survival (PFS) were compared between the two drugs. Results: A total of 182 (100 gefitinib vs. 82 erlotinib) of 584 patients treated by targeted agents had squamous histology. Of the 182 patients, 167 (91.7%) were male and 159 (87.4%) were smokers. The ORR and disease control rate (DCR) were 4.9% and 40.6%, and there was no significant difference between gefitinib and erlotinib (ORR, 5.0% vs 4.8%; p=0.970; DCR, 40.0% vs 41.4%; p=0.439). The median OS in the gefitinib group was 12.1 months, and that in the erlotinib was 12.7 months (hazard ratio [HR], 1.282; 95% confidence interval [CI], 0.771∼2.134; p=0.339). The median PFS for the gefitinib group was 1.40 months, compared with 1.37 months for the erlotinib group (HR, 1.092; 95% CI, 0.809∼1.474; p=0.564). Skin rash ≥grade 3 was more common in erlotinib (12.2%) than gefitinib (1.0%, p=0.003) groups. Conclusion: This retrospective study showed that the two drugs appear to have similar antitumor efficacy and toxicity except for skin rash.

Routine barium enema prior to closure of defunctioning ileostomy is not necessary

Sung Yeon Hong,Do Yun Kim,Seung Yeop Oh,Kwang Wook Suh 대한외과학회 2012 Annals of Surgical Treatment and Research(ASRT) Vol.83 No.2

Purpose: The use of barium enemas to confirm the anastomotic integrity prior to ileostomy closure is still controversial. The purpose of the study was to determine the utility of routine contrast enema prior to ileostomy closure and its impact on patient management in patients with a low pelvic anastomosis. Methods: One hundred forty-five patients had a temporary loop ileostomy constructed to protect a low colorectal or coloanal anastomosis following low anterior resection for rectal cancer. All patients were evaluated by physical examination, proctoscopy, and barium enema prior to ileostomy closure. Results: The median time from ileostomy creation to closure was 8 months. Five (3.5%) of the 144 patients were found to have clinically relevant strictures at the colorectal anastomosis on routine barium enema. One patient (0.7%) showed anastomotic leak on their barium enema. Overall, 141 patients (97.9%) had an uncomplicated postoperative course. Postoperative complication occurred in three patients (2.1%). None of them showed abnormal barium enema finding, which suggested that routine contrast enema examination did not predict postoperative complication. Conclusion: Routine barium enema evaluation of low pelvic anastomoses before loop ileostomy closure did not provide any additional information for postoperative colorectal anastomotic complication.

Bacterial Population Dynamics of Korean Cabbage Kimchi with Different Jeotgal, Salt-fermented Seafood

Sung Wook Hong,Yun-Jeong Choi,Hae-Won Lee,Mi-Ai Lee 한국식품영양과학회 2015 한국식품영양과학회 학술대회발표집 Vol.2015 No.8

Changes in serum magnesium concentration after use of a proton pump inhibitor in patients undergoing percutaneous coronary intervention

( Sang Ho Park ),( Sun Hyo Lee ),( Ji Sung Lee ),( Won Yong Shin ),( Hyo Wook Gil ),( Jong Oh Yang ),( Eun Young Lee ),( Sae Yong Hong ) 대한신장학회 2015 Kidney Research and Clinical Practice Vol.34 No.2

Background: Although cross-sectional studies have suggested a relationship between proton pump inhibitor (PPI) use and hypomagnesemia, no large-scale cohort study has been conducted to date. Here, we examined the changes in serum magnesium levels in response to PPI use. We hypothesized that PPI use might change the serum magnesium concentration. Methods: Of the 2,892 patients hospitalized for percutaneous coronary intervention between January 2007 and May 2012, 1,076 patients with normal baseline (1.6- 2.5 mg/dL) and follow-up serum magnesium concentrations were enrolled. These patients were divided into two groups: the PPI group and the control group. Results: The mean follow-up period was 9.5172.94 months. The incidence of hypomagnesemia (o1.6 mg/dL) was 0.4% (3/834) in the PPI group and 0.4% (1/242) in the control group (P ¼0.904). The change in magnesium levels did not differ between the two groups, and this result was maintained in the analysis of covariance after adjusting for confounding factors (P ¼ 0.381). Moreover, magnesium levels did not significantly differ between the long-term (duration of use Z12 months, n ¼ 71) and short-term PPI groups (duration of use o12 months, n ¼ 763), and the control group (n ¼ 242; P ¼ 0.620). The effect of PPI use on change in serum magnesium concentration was affected by the use of multiple diuretics ( 0.0170.25 mg/dL; P ¼ 0.025), although a single diuretic use with PPI did not alter the change in magnesium level (0.1270.27 mg/dL). Conclusion: Changes in magnesium levels might be subtle after PPI use in patients with normal baseline magnesium values.

Reanalysis of membranoproliferative glomerulonephritis patients according to the new classification: a multicenter study

( Sung Ae Woo ),( Hye Young Ju ),( Soon Hyo Kwon ),( Ji Hye Lee ),( Soo Jeong Choi ),( Dong Cheol Han ),( Seung Duk Hwang ),( Sae Yong Hong ),( So Young Jin ),( Hyo Wook Gil ) 대한신장학회 2014 Kidney Research and Clinical Practice Vol.33 No.4

Background: All types of membranoproliferative glomerulonephritis (MPGN) areprogressive diseases with poor prognoses. Recently, a newly proposed classificationof these diseases separated them into immune complex- and complementmediateddiseases. We investigated the frequency of C3 glomerulonephritis amongpreviously diagnosed MPGN patients. Methods: We conducted a retrospective study of patients diagnosed with MPGN atthree tertiary care institutions between 2001 and 2010. We investigated theincidence of complement-mediated disease among patients diagnosed with MPGN. Progressive renal dysfunction was defined as a 50% reduction in the glomerularfiltration rate or the need for renal replacement therapy. Results: Among the 3,294 renal biopsy patients, 77 (2.3%) were diagnosed withMPGN; 31 cases were excluded, of which seven were diagnosed with systemic lupusnephritis, and the others were not followed for a minimum of 12 months afterbiopsy. Based on the new classification, complement-mediated MPGN was diagnosedin two patients (4.3%); only one patient developed progressive renaldysfunction. Among the immune complex-mediated MPGN patients, 17 patientsdeveloped progressive renal dysfunction. Serum albumin and creatinine levels atthe time of MPGN diagnosis were risk factors of renal deterioration, after adjustingfor low C3 levels and nephrotic syndrome. Conclusion: Complement-mediated glomerulonephritis was present in 4.3% ofpatients previously diagnosed with MPGN.