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<SUP>18</SUP>F-FDG PET-CT에서 진단된 갑상선 우연종의 악성종양 발견율 및 특징
이강영,고건<SUP>1<.SUP>,김선국<SUP>1<.SUP>,고진철<SUP>1<.SUP>,김행수,최상용,박신희,박용휘<SUP>2<.SUP>,Kang Young Rhee,Gun Koh,<SUP>1<.SUP>,Sun Kuk Kim,<SUP>1<.SUP>,Jin Chul Koh,<SUP>1<.SUP>,Haeng Soo Kim,Sang Yong Choi,Shin 대한갑상선-내분비외과학회 2008 The Koreran journal of Endocrine Surgery Vol.8 No.1
<B>Purpose: </B>PET-CT is often used to differentiate benign or malignant thyroid incidentalomas. In this retrospective study, we evaluated whether the <SUP>18</SUP>F-FDG uptake pattern and PET-CT findings improved accuracy over the standardized uptake value (SUV). <B>Methods:</B> <SUP>18</SUP>F-FDG PET-CT was performed on 2,178 subjects from August, 2004, to October, 2007, in Sung-ae Hospital. PET-CT was performed on 806 patients (37%) with suspected or known nonthyroidal cancer and 1,372 healthy subjects (63%) without a previous history of cancer. We investigated the clinical characteristics of patients, history, standardized uptake value (SUV), ultrasonography, and hormone levels in blood. Thyroidal cancer was confirmed by ultrasonography-guided fine needle aspiration and pathology after thyroid operation. <B>Results:</B> The prevalence of focal thyroid lesions on PET-CT was 8.8% (191/2178). Thyroid cancer confirmation was 7.9% (15/191). The maximum SUV of malignant thyroid lesions were significantly higher than that of benign lesions (7.00±3.08 vs. 4.49±1.84, P<0.001). <B>Conclusion:</B> PET-CT image interpretation that includes 18F-FDG uptake and SUV is better than PET-CT alone for differentiating benign and malignant lesions. Thyroid cancer risk increases as SUVmax levels increase. <B>(Ko</B><B></B><B>rean J Endocrine Surg 2008;8:38-42)</B>
혈액암환자에서 조혈모세포 이식 후 따르는 헤르페스 바이러스 감영 양상
이호섭,탁희상,신성훈,김양수,남성진,김혜수,박진희,정수현,김성빈,김예나 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.1
배경 : 헤르페스바이러스과에는 단순포진 바이러스(HERPES SIMPLEX VIRUS, HSV), 수두대상포진 바이러스 (VARICELLA-ZOSTER VIRUS, VZV), 엡스타인-바 바이러스 (EPSTEIN-BARR VIRUS, EBV), 그리고 거대세포 바이러스 (CYTOMEGALOVIRUS, CMV) 등이 있다. 헤르페스바이러스 감염은 혈액암환자에서 조혈모세포 이식 환자에서 전파 (dissemination), 이차감염, 세균 중복 감염의 심각한 합병증을 일으킬 수 있다. 하지만 항암약물치료를 받는 림파종 환자에서 항 바이러스 약제의 사용 용량과 기간에 대한 concensus는 없다. 헤르페스바이러스 감염에 대한 발생율과 위험인자를 후향성으로 분석하였다. 방법 : 고신대학교 복음 병원에서 1995년 6월부터 2009 년 2월 사이에 새롭게 진단되어 조혈모세포 이식을 받은 전체 58명의 환자들이 후향적으로 현 연구에 등록했다. 헤르페스 바이러스 감염은 임상적 진단, 혈청학적 검사 또는 병리학적 진단에 기초하여 확진한다. 환자들의 특성은 다음과 같다: 평균 연령은 44세 (범위 19-62세)였고 남녀비는 30:28이었다. 등록된 질환은 백혈병 (n=9, 15.5%), 림프종 (n=30, 51.7%), 다발성 골수종 (n=12, 20.7%), 재생불량성 빈혈 (n=6, 10.3%) 그리고 골수이형성증후군 (n=1, 1.7%)이 포함되었다. 결과는 chi-squre test나 independent samples T test를 사용하여 분석되었다. Multivariate analysises에 대해 logistic regression test를 사용하였다. 결과 : 15명의 환자들 (25.9%)에서 조혈모세포 이식후 헤르페스 바이러스 감염이 발생하였다. 조혈모세포 이식 5년간 누적 발생율은 53.9%였다. Univariate analyses에서 헤르페스 바이러스 감염에 대한 유의한 위험 인자는 없었다. 하지만 조혈모세포 이식후 생존 기간(40.18 ± 30.14 months vs 20.06 ± 26.67 months, p=0.018)은 헤르페스 바이러스 감염의 낮은 발병율과 유의한 관련성이 있었다. 이식 편대 숙주질환 (GVHD)의 존재 (37.5% in developed GVHD vs 0% in no GVHD, p=0.200), 동종조혈 모세포 이식에서 면역억제요법의 기간 (15.98 ± 14.02 months vs 6.78 ± 3.67 months, p = 0.374)은 헤르페스 바이러스 감염에 대한 위험인자가 아니었다. 결론 : 조혈모세포 이식 후 생존 기간은 어사이클로비어 예방을 받은 혈액암 환자에서 헤르페스 바이러스 감염의 낮은 발병율과 연관성이 있는 것으로 보인다. 저용량의 어사이클로비어 예방은 헤르페스 바이러스 감염의 고위험군인 조혈모세포 이식을 받은 혈액암 환자에 필요하리라 생각된다. Background : Herpesviridae family includes herpes simplex virus, varicella zoster virus, Epstein-Barr virus, and cytomegalovirus, etc. Herpesviridae viral infection (HVI) can lead to serious complications including dissemination, secondary infection, bacterial superinfection in patients with hematologic malignancy following hematopoietic stem cell transplantation (HSCT). But there was no consensus on the dose and duration of antiviral agents prophylaxis in patients undergoing chemotherapy. We retrospectively analyzed the incidence and the risk factors for HVI. Method : A total of 58 patients who newly diagnosed and received HSCT with prophylaxis of acyclovir at the Kosin University Gospel Hospital, Busan, Korea between June 1995 and February 2009 were enrolled retrospectively in the current study. HVI was confirmed based on clinical diagnosis, serologic test or pathologic diagnosis. The characteristics of the patients were as follows: the median age was 44 years (range 19-62 years) with a female-to-male ratio of 30:28. The enrolled diseases included leukemia (n=9, 15.5%), lymphoma (n=30, 51.7%), multiple myeloma (n=12, 20.7%), aplastic anemia (n=6, 10.3%) and myelodysplastic syndrome (n=1, 1.7%). The results were analyzed using a chi-square test and independent samples T test. For the multivariate analysis, we used logistic regression test. Results : Fifteen patients (25.9%) developed HVI after HSCT. The cumulative incidence of HVI was 53.8% at 5 years after HSCT. In univariate analysis, there was no significant risk factor for HVI. The presence of graft-versus-host disease (GVHD) (37.5% in developed GVHD vs. 0% in no GVHD, p=0.200), duration of immunosuppressive therapy (IST) in allo-SCT (15.98 ± 14.02 months vs. 6.78 ± 3.67 months, p = 0.374) were not risk factors for HVI. Conclusion : The incidence of HVI was similar to that in historical other studies. There was no risk factor associated with development of HVI. Most of the HVI occurred within the first 24 months after transplantation. So long term use of antiviral prophylaxis may be needed to prevention of HVI after HSCT.
Vector Golf 분석시스템을 통한 테니스 포핸드 드라이브 동작의 운동역학적 분석
성영호,김성섭 龍仁大學校 2005 용인대학교 논문집 Vol.23 No.-
The propose of this study is to closely examine the characteristics of kinematics variables, which are time spend of movement, speed of the racket, degree of the racket, angle of racket face on impact, ball spin, and biomechanical variables, which is center of gravity on both feet by analyzing the movement of forehand drvie technique of tennis performed by 5 top university athletes through Vector Golf Analysis System. The results of analysis on biomechanical variables are listed below. 1) The average time spend of forehand drive technique from ready position to impact was 1.16 sec. 2) The average speed of the racket of forehand drvie technique from ready position to impact was 69.4mile/hour. 3) The average degree of the racket of forehand drive technique was out in 4.1˚. 4) The average angle of the racket on impact of forehand drive technique was close 5.1˚, which was closed swing. 5) The average ball spin after the impact of forehand drive technique was slice 0.1˚. 6) The center of gravity percentage on both feet on each events of forehand drive technique, when ready position it was 33.3% on right. 66.8% on left, when back swing, 95.8% on right, 4.2 on left, when impact, 24.3% on right, 75.7%on left, and when follow-through it was 1.4% on right and 98.6% on left. After this study of analyzing biomechanical variables of forehand drive technique of tennis, the proposals for the farther studies are listed below. 1) Analysis on position change factors of each events 2) Analyze with different level of sensor 3) Comparison analysis between elite athletes and armature athletes 4) Record with high-speed camera
신상섭 韓國植物ㆍ人間ㆍ環境學會 1999 인간식물환경학회지 Vol.2 No.1
The purpose of this study was an alternative suggest landscape planting design approach in community of residential site. The results were summarized as follows; Firstly, character of landscape planting space must have been designed after due consideration of planting position and visual angle, functional structure and landscape value, planting for energy preservation etc. Secondly, planting space in residential environment must have been great emphasis of various planting pattern, selection of main species of tree and stock planting design etc. Thirdly, landscape planting design make efficient use of ground cover planting and vine trees, native plants, moreover must be grope for harmony of natural landscape and relief of native beauty. Fourthly, preservation feasible excellent trees and green area must have been consideration from site planning process and encourage compensation system. Fifthly, planting design of residential outdoor space must have been induce fruit trees, fragrance trees, aquatic trees, moreover secure of species variety and lure wildlife out, induction of self perpetuating environment.
박정섭,장일영,송재호,한상묵 金烏工科大學校 1998 論文集 Vol.19 No.-
The method of finite element analysis is modified in this study to predict the material nonlinear behavior of reinforced concrete structure more properly. It is difficult to predict the behavior of reinforced concrete structure due to the development of concrete crack, the behavior of compressive failure, bond properties between concrete and steel, and shear resistance. To predict the material nonlinear behavior of reinforced concrete structure more properly, the stress-strain relationship of confined concrete which proposed by Attard, Setunge is considered. Also, shear retention model is considered. To prove the efficiency of the analysis, analytical results are compared to experimental results.
활성탄 및 제올라이트에 대한 수소, 이산화탄소 및 일산화탄소의 흡착특성에 관한 연구
徐成燮 弘益大學校 科學技術硏究所 1994 科學技術硏究論文集 Vol.5 No.-
Adsorption equilibria of hydrogen, carbon dioxide, and carbon monoxide on activated carbon and zeolite have been studied by static volumetric method. Experimental results are compared with Langmuir isotherm, Langmuir-Freundlich isotherm, and Flory-Huggins vacancy solution theory(F-H VST). Adsorption equilibria on activated carbon are described fairly well with the above isotherms. Among them, Langmuir-Freundlich isotherm and F-H VST show the best agreement with the experimental results. On the contrary, adsorption equilibria on zeolite are not predicted by Langmuir isotherm. Adsorption of carbon dioxide on ZMS 13X and ZMS 4A reach saturation state above 1 atm. Adsorbed amount of carbon dioxide on zeolite is larger than on activated carbon below 1 atm. Difference between adsorbed amount of carbon dioxide and hydrogen is larger for ZMS 13X than for ZMS 4A. As operating pressure increases activated carbon would be better than zeolite for separation of gas mixture of hydrogen, carbon dioxide, and carbon monoxide.
정신훈련이 아동들의 정신기술, 신체효능감과 경쟁불안에 미치는 효과
송성섭,김정수 世明大學校 1998 世明論叢 Vol.7 No.-
The purpose of this study was to examine the effect of mental training on mental skill, physical self-efficacy, and competition anxiety. The subjects were randomly assigned to experiment group and control group in which included group grade 69 students; 40 involved in experimet group and 29 involved in control group. Teacher and stduents were instructed about the purpose of this study, instruction contents, and education of mental training before experimene treatment. Pre-test were measured with mental skill, physical self-efficacy, and competition anxiety, mental skill was included with subcomponents of relazation, stress, positive thought, and goal-setting, mental training program was treated for the 20 minute a day on 2 months. Post-test was used with same questionnaire of Pre-test. The conclusions are as followings ; 1. The mental training program has an statistically influence in the relaxation. 2. The mental training program has an statistically influence on the goal-setting. 3. The mental training program does not have an influence on the stress. 4. The mental training program does not have an influence on the positive thought. 5. The mental training program does not have an influence on the physical self-efficacy. 6. The mental training program does not have an influence on the competition anxiety.
오환섭,정효진,박상필,손두익 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-
The damage of the pressure courage by degradation can become the reason of unexpected break down or failure accident and it is very important because safety accident, the production loss, environmental pollution, social problems are occur. Consequently The result to investigat of failure accident for domestic pressure vessel, the factor of degradation is SCC, Sorrosion, Cavity, Crack
한상섭,권정중,이갑연,허성두,김하선,김종원 江原大學校 森林科學硏究所 2003 Journal of Forest Science Vol.19 No.-
이 연구는 가시오갈피 엽의 생리적 특성을 밝히고자 광합성, 기공증산, 기공전도도의 생리반응을 측정한 것으로 결과를 요약하면 다음과 같다. 1. 광보상점은 양엽이 약 30 μ mol m^(-2) s^(-1), 음엽이 약 15 μ mol m^(-2) s^(-1) 이었다. 2. 광포화점은 양엽이 약 1,000 μ mol m^(-2) s^(-1), 음엽이 약 300 μ mol m^(-2) s^(-1) 이었다. 3. 우리나라 및 중국산 가시오갈피 상엽의 순광합성속도는 약 8.0-8.8 μ mol m^(-2) s^(-1) 로 산지간에 유의차가 인정되지 않았다. 제주산 섬가시오갈피 상엽은 약 6.9 μ mol m^(-2) s^(-1) 로 다소 낮았다. 4. 모든 산지에서 중위엽의 순광합성속도는 상엽의 40-65%, 하위엽은 상엽의 30% 정도이었다. 그러나 섬가시오갈피 하엽은 상엽의 약 71%로 다소 높았다. 5. 상엽의 기공증산속도는 1.1-1.4 mmol H₂O m^(-2) s^(-1), 중위엽은 0.7-1.0 mmol H₂O m^(-2) s^(-1), 하위엽은 0.5-0.6 mmol H₂O m^(-2) s^(-1)로 산지별로 유의차가 없었다. 6. 기공전도도는 상엽이 약 70-90 mmol H₂O m^(-2) s^(-1)로 산지별 유의차가 인정되지 않았다. 그러나 제주 섬가시오갈피 상엽은 약 380 mmol H₂O m^(-2) s^(-1)로 타산지보다 현저히 높았다. This study was made on the physiological reactions of photosynthesis, stomatal transpiration, stomatal conductance of Acanthopanax senticosus of leaves. The resuits obtained are as follows : 1. The light compensation points were approximately 30μ㏖ m^(-2)s^(-1) in sun leaves and 15μ㏖ m^(-2)s^(-1) in shade leaves. 2. The light, saturation points were approximately 1,000μ㏖ m^(-2)s^(-1) in sun leaves and 300μ㏖ m^(-2)s^(-1) in shade leaves. 3. There was no significant between various mountains distributed, net photosynthetic rates were approximately 8.0 to 8.8μ㏖ m^(-2)s^(-1) in upper leaves. However, net photosynthetic rate in upper leaves of Acanthopanax koreanum in Jeju island was slightly low about 6.9μ㏖ m^(-2)s^(-1). 4. Net photosynthetic rate in middle leaves of all mountains was ranged from 40% to 65% of upper leaves, and that in lower leaves was approximately 30% of upper leaves. But, the net photosynthesis in lower leaves of Acanthopanax koreanum in Jeju island was slightly high about 71% of upper leaves. 5. There was no significant between various mountains distributed, stomatal transpirations were ranged from 1.1 to 1.4 mmol H₂Om^(-2)s^(-1) in upper leaves, 0.7 to 1.0 mmol H₂O m^(-2)s^(-1) in middle leaves, and 0.5 to 0.6 mmol H₂0m^(-2)s^(-1) in lower leaves, respectively. 6. There was no significant between various mountains distributed, the stomatal conductance in upper leaves was ranged from 70 to 90 mmol H₂O m^(-2)s^(-1) . However, stomatal conductance in upper leaves of Acanthopanax koreanum in Jeju island was approximately 380 mmol H₂O m^(-2)s^(-1), its remarkedly higher than any other mountain.