http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Quantitative Assay for the Binding of Jun-Fos Dimer and Activator Protein-1 Site
Lee, Sang-Kyou,Park, Se-Yeon,Jun, Gyo,Hahm, Eun-Ryeong,Lee, Dug-Keun,Yang, Chul-Hak Korean Society for Biochemistry and Molecular Biol 1999 Journal of biochemistry and molecular biology Vol.32 No.6
The Jun and Fos families of eukaryotic transcription factors form heterodimers capable of binding to their cognate DNA enhancer elements. We are interested in searching for inhibitors or antagonists of the binding of the Jun-Fos heterodimer to the activator protein-1 (AP-1) site. The basic-region leucine zipper (bZIP) domain of c-Fos was expressed as a fusion protein with glutathione S-transferase, and allowed to form a heterodimer with the bZIP domain of c-Jun. The heterodimer was bound to glutathione-agarose, to which were added radiolabeled AP-1 nucleotides. After thorough washing, the gel-bound radioactivity was counted. The assay is faster than the coventional electrophoretic mobility shift assay because the gel electrophoresis step and the autoradiography step are eliminated. Moreover, the assay is very sensitive, allowing the detection of picomolar quantities of nucleotides, and is not affected by up to 50% dimethylsulfoxide, a solvent for hydrophobic inhibitors. Curcumin and dihydroguaiaretic acid, recently known inhibitors of Jun-Fos-DNA complex formation, were applied to this Jun-GST-fused Fos system and revealed to decrease the dimer-DNA binding.
실용음악 전공 학생들의 발성치료 전후 성대 및 음성 특성 비교
황연신,심미란,김철준,최용석,김상연,최찬호,선동일,Hwang, Yeon Shin,Shim, Mi Ran,Kim, Chul Jun,Choi, Yong Suk,Kim, Sang Yeon,Choi, Chan Ho,Sun, Dong Il 대한후두음성언어의학회 2016 대한후두음성언어의학회지 Vol.27 No.2
Background and Objectives : Many students major in applied music singing have various difficulties in phonation when they sing or perform. But the studies about this cause are lack. The purpose of this study is whether singing voice therapy based on vocal music is effective or not to applied music singing students that have difficulties in phonation. Materials and Methods : Singing voice therapy program had been done to 8 students major in applied music singing during 7 weeks. We did laryngeal stroboscope, perceptual, acoustic and aerodynamic examination before and after singing voice therapy to this students. And we studied post examination results have differences or improvements compared to pre examination results. Results : Four male students don't have effective improvement after singing voice therapy but they shows slight improvement in aerodynamic examination values compared to pre examination values. Four female students shows improvement in aerodynamic examination values and pitch range increasing. Above all, one student's vocal nodules disappeared after singing voice therapy. Conclusion : Singing voice therapy based on music singing is very effective to the students major in applied music singing. Above all, their curriculum in applied music singing should include phonation training based on music singing before training perform and technic practices.
SAS CALIS 절차를 이용한 효과적인 구조방정식 모형의 사용
전성해 청주대학교 산업과학연구소 2008 産業科學硏究 Vol.25 No.2
We propose an efficient usage of structural equation model using SAS CALIS procedure in this paper. There have been many softwares of structural equation model, such as, RISREL, AMOS, and so forth. These are exclusive softwares for structural equation model. As the case may be, we need other statistical analysis functions as well as structural equation model. But, traditional softwares for structural equation model are insufficient as general statistical analysis tools. So, in this paper, we use SAS system for structural equation model and additional statistical modeling. The SAS system has CALIS procedure for structural equation model. Also, it has many tools for general statistical analysis.
전승철,박성한 漢陽大學校 工學技術硏究所 1998 工學技術論文集 Vol.7 No.1
사람의 얼굴은 일반 객체와는 다르게 정확히 구별되는 특징을 가지고 있지 않다. 따라서 일반적으로 사람 얼굴에 관한 연구에서는 인간이 사람의 얼굴을 볼 때 가장 먼저 인식을 하는 눈, 코, 입을 특징으로 정하고 있다. 이러한 특징은 사람에 따라 다르게 나타나며 주위환경에 영향을 받는다. 따라서 이러한 사람의 특징을 정확히 찾아내는 것이 중요하다. 본 논문에서는 얼굴 특징점의 기하학적 성질을 이용 제약조건을 제시하여 제약조건에 만족하는 객체를 후보객체로 설정하였다, 그리고 눈, 코, 입 각각의 알고리즘을 제안하여 원하는 특징점을 효율적으로 찾아내는 알고리즘을 제안하고 있다. 제안된 알고리즘은 일반적인 사람 얼굴 영상에 대해 빠른 속도로 특징점을 찾아내고 있다. The human faces do not have distinct features unlike other general objects. In general the features defined eyes, nose and mouth which are firstly recognized when human being see the face. These features have different characteristics each human face. Therefor, the exactly finding the human features are very important. In this paper proposed an algorithm finding eyes, nose and mouth using the geometric characteristics of human face. candidate objects are found by the constraints of features. And then each proposed algorithm of eyes, nose and mouth is using for finding exactly objects. The proposed algorithm fast find the features in general human face image.
가시광선과 아르곤 레이저에 의한 복합레진 중합 효과의 비교 연구
전상언,김용기 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.2
The purpose of this study was to evaluate the shear bond strengths,microhardness,compressive strength and contraction gap at the resin-tooth interface of two types of composite resins polymerized with visible light and argon laser sourse. The results from the present study can be summarized as follows: 1.Resin sample polymerized either by argon laser or visible light did not show significant difference in their physical properities tested(p>.05). 2.The contraction gap at the resin tooth interface was found to be present in all samples but any significant difference between groups could not be established due to their variability.Although the superiority of argon laser over visible light in enhancing the physical properities of resin could not be elucidated in the present study,continous efforts are deemed to be worthwhile to investigate this using different conditions and materials of experiment.
전찬덕,이상래,황의환 大韓口腔顎顔面 放射線學會 1993 Imaging Science in Dentistry Vol.23 No.1
The purpose of this study was to evaluate the clinical and radiographic features of 35 cases of nasopalatine duct cyst by means of the analysis of periapical and/or occlusal radiograms in 35 persons visited the Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyung Hee University and Chonbuk National University. The obtained results were as follows: 1. The incidence of nasopalatine duct cysts was higher in males(74.3%) than in females(25.7%). 2. The nasopalatine duct cysts were the most frequently occurred in the 4th decades(34.3%). The 6th and 7th decades(17.1%, 17.1%) were next in order to frequency followed by the 5th decades(14.3%), the 3rd decades(8.6%), the 2nd decades(5.7%), and 8th decades(2.9%). 3. In the signs and symptoms of nasoplatine duct cysts, 25.7% were swelling, 17.1% were swelling and tenderness, 20.0% were swelling and pain, and 37.2% were a symptom. 4. In the shape of nasopalatine duct cysts, 40.0% were round type, 48.6% were oval type, and 11.8% were heart type, In symmetry of the nasopalatine duct cysts to the median palatine surture, 85.7% were symmetry, 14.3% were asymmetry. 5. In the width of nasopalatine duct cysts, 11.4% were 6-10mm, 48.6% were 11-20mm, 25.7% were 21-30mm, and 14.3% were 31-40mm. 6. In the periphery of nasopalatine duct cysts., 82.9% were distinct, 17.1% were relatively distinct. 7. In the change of root, 51.5% were intact, 17.1% were root divergence, 20.0% were root resorption, and 11.4% were root divergence and resorption.
受動的 體位變化에 따른 循環 및 呼吸反應에 미치는 副交感神經 遮斷劑의 影響
全相年,蔡義業 慶北大學校 醫科大學 1979 慶北醫大誌 Vol.20 No.2
Orthostasis에 미치는 부교감신경 차단제의 영향을 추궁하기 위하여 thiopental sodium으로 마취한 실험동물을 경사대에 고정한 후 수동적으로 수평, 기립 및 도립위로 체위를 변화시키면서 각 체위에서 10분간 분시심박수, 평균혈압, 중심정맥압, 분시호흡수, 뇌파 및 혈액의 호흡개스와 pH에 대하여 측정하여 무처치 정상대조군과 atropine 투여군을 비교 관찰하였다. 분시심박수는 atropine투여군에서 비투여군에 비하여 기립시에 증가하는 경향이었다. 도립시에는 양군이 다같이 감소하였으나 atropine 투여군에서는 그 감소의 정도가 적었다. atropine 투여군은 평균혈압이 기립시에 비투여군에 비하여 상승되었고 도립시에는 혈압하강의 정도가 적었다. 기립시에 비투여군의 혈압은 매우 감소하였다. 중심정맥압은 atropine 투여군은 수평위에서 감소하였으며 기립위에서는 양군이 다 같이 감소하였으나 atropine 투여군에서 감소율이 적었다. 도립위에서 양군이 다 같이 증가하였으나 그 증가율이 atropine 투여군에서 더 높았다. 분시호흡수는 atropine 투여군은 비투여군에 비하여 호흡수가 증가하였고 체위변화시의 호흡수 변화는 기립시에는 양군이 다 감소하였으나 atropine 투여군은 감소율이 적었다. 도립시에는 양군이 다 같이 증가하였으나 atropine 투여군은 그 변화가 적었다. 즉 체위변화에 의한 호흡수의 변화는 atropine 투여군이 비투여군에 비하여 변화율이 적었으며 호흡수가 안정되어 있었다. atropine 투여시 혈액의 pH 및 호흡개스분압의 각 체위변화에 따른 결과는 다음과 같다. 혈액 pH는 도립시 약간 증가하였으며 Paco_2는 기립시 증가하고 도립시 감소하였으며 Pvco_2는 기립 및 도립시에 다같이 증가하였다. Pao_2는 기립시 감소하였으며 Pvo_2는 기립 및 도립위에서 감소하였다. 뇌파는 양군이 다 같이 마취의 영향에 의하여 서파(slow wave)가 우세하였으며 atropine 투여군은 체위변화 초기에 속파(β파) 출현이 많았으며 기립 및 도립에서 뇌파의 파고 감소는 atropine 투여군이 적었다. 부교감신경 차단제의 효과는 투여군의 중심정맥압의 대조치가 처음에 감소하는 것을 제외하고는 orthostasis를 방지하는데 효과적이라고 생각된다. To evaluate the effect of atropine on the orthostatic tolerance with blocking of cholinergic cardiac inhibitory fiber of the vasovagal reflex, and the prevention from the stress relaxation of peripheral vessel in gravity dependent region with blocking of cholinergic vasodilator fiber in the skeletal muscle, we injected 30∼60 ㎍m/kg, body weight of atropine sulfate to experimental animals previously, and compared the findings of the atropine injected animal with the control animal by the orthostatic tolerance in the passive tilt. Aneshetized dogs were tilted from supine to 90°upright and 90°head down position. Measurements were made of heart rate (HR), mean blood pressure (BP), central venous pressure(CVP), respiratory rate(RR), EEG, and Po_2, Pco_2 and pH of blood before, during, and after each postural change on 20 dogs after parasympathetic blockade. On atropine, HR increased in supine and increased further in upright. HR decreased in head down in both atropine and the controls. However HR was less affected on atropine. BP increased on atropine in supine. BP was less decreased in upright and head down on atropine while BP markedly decre ased in upright in the controls. CVP decreased on atropine in supine, and CVP decreased in upright in both groups. However CVP was slightly changed on atropine. CVP increased in head down in both groups. However CVP was more increased on atropine. RR increased on atropin in supine, RR decreased in urpight in both groups. However RR was less decreased on atropine. RR increased in head down. On the other hand, RR was less increased on atropine. In addition Pao_2 rose substantially in head down in both groups, but the finding shows that Pao_2 stayed relatively unchanged on atropine. Diminution of amplitude and frequency of EEG in upright and head down is less marked on atropine. It is concluded that atropine has no clear cut effect on cardiorespiratory responses to tilt except for its BP effect.
퇴비 및 액비 시용에 따른 수수×수단그라스와 이탈리안라이그라스 작부체계의 수량과 양분흡수량 및 토양 유효 질소 및 인 변화
임상선,이광승,전병준,이세인 全南大學校 農業科學技術硏究所 2011 農業科學技術硏究 Vol.46 No.-
This study was conducted to investigate productivity and nutrients uptake of Sorghum×Sudan grass (SSG) and Italian ryegrass (IRG) cropping system with cattle manure compost and liquid pig manure application, respectively. Changes in mineral N and available P concentration before and after each cropping were also examined. Dry matter yield ranged from 2.12 to 2.86 ton ha-1 for SSG and from 3.57 to 6.08 ton ha-1 for IRG. Forage productivity observed in this study was substantially lower than other studies probably due both to low precipitation during cropping season and to soil characteristics; lower pH (<5) and available P concentration (ranged from 98.6 to 174.8) than the soils used in the previous studies. The uptake of N and P also showed very similar pattern to dry matter yield; IRG had higher nutrients uptake than SSG. According to nutrient balance analysis, 76.4% of N and 76.9% of P2O5 applied to the fields (161 kg N ha-1 and 265 kg P2O5 ha-1) were not assimilated by SSG. For IRG, 50.2% (133 kg N ha-1) of N applied (265 kg N ha-1) was not taken up; meanwhile, the amount of P2O5 assimilated by IRG was 75 kg P2O5 ha-1, and this was 49 kg P2O5 ha-1 more than that of applied P2O5 (26 kg P2O5 ha-1) as liquid manure, indicating additional P uptake from the soils. Accordingly, mineral N (NH4 + and NO3 -) and available P concentrations of the soils increased after SSG harvest as compared with the soils before cultivation, but they decreased after IRG cultivation. Such differences in nutrient uptake by plant and soil nutrient availability could be attributed to the contrasting availability of nutrients in the compost and liquid manure. Organic forms of nutrients included in the compost is likely to be released slowly by decomposition of organic matter and thus the nutrients released could be utilized by the next crop (IRG) rather than by the crop (SSG) to which compost was applied. On the other hand, as most nutrients in liquid manure is readily available, N and P in the liquid manure could be assimilated by IRG. Therefore, it might be necessary to consider both compost (slowly available) and liquid manure (rapidly available) to achieve a goal production of forage.
기저질환이 없는 사람에서 발생한 Campylobacter fetus에 의한 재발성 심내막염 1예
전재범,정진원,김성혜,송문희,오형철,안성기,최상호,김남중,김양수,우준희,류지소 대한감염학회 2004 감염과 화학요법 Vol.36 No.6
C. fetus 심내막염은 드물게 발생하는 질환으로 주로 면역능이 저하된 환자에서 발병하고 대동맥판을 침범하는 경우가 많으며 적절한 치료가 되지 않을 경우 치사율이 높다. 저자들은 기저질환이 없던 69세 남자에서 C. fetus 심내막염을 경험하였기에 문헌고찰과 함께 보고하는 바이다. 환자는 발열로 내원하여 시행한 혈액배양 검사상 C. fetus가 동정되었고 경식도 초음파 검사상 삼첨판에 증식증이 발견되어 심내막염 진단하에 ceftriaxone에 이어 meropenem으로 총 4주간 항생제를 투여받고 호전되었다가 한달 후 다시 재발하였고 판막부전 소견 진행하여 삼첨판 치환술을 시행받고 전신상태 호전되어 퇴원하였다. Campylobacter fetus is a rare cause of endocarditis. To date, only about 30 cases of C. fetus endocarditis have been reported mainly in the elderly with chronic underlying illnesses. Most cases showed tendency to involve aortic valve. This report describes a case of native tricuspid valve infective endocarditis in a 69-year-old man without any underlying disease. Despite adequate antibiotic therapy for 4-weeks, endocarditis recurred and leading to surgical valve replacement.