자기공명영상을 이용한 정신분열병 환자의 뇌량크기 측정

성상율,구자섭,조근호,원승희,이종훈,박종한 대한생물치료정신의학회 2004 생물치료정신의학 Vol.10 No.1

Objectives : Nowadays many studies with MRI have reported structurai abnormalltles of corpus callosum of schizophrenic patients. However, the results are various and inconstant. In this study, we attempted to identify structural change of C O ~ U S cailosurn. Method : We measured the size of corpus callosum of the 24 schizophrenia patients (male 11, female 18) who were diagnosed by DSM-IV (19943, visited at department of psychiatry, catholic university hospital of Daegu from January 2002 to December 2003, by using midline sagittal slice of MRI. These results were compared with the size of corpus callosum of 25 controls (male 7, female 78). We divided corpus callosurn into 7 areas. We calculated and compared the areas of each subregion, mid-sagittal cerebral area, and entire corpus callosum. The results were analyzed by independent t-test. Result :When we compared subregion to corpus callosum adjusted wth mid-sagittal cerebral area, schlzoph-renia patients had significantly smaller genu (1.64k0.32 vs. 1.43k0.26 p<O.O5) and splenium (2.16f0.27 VS. 1.96+0.30 ; ~(0.05). Similarly, the ratio of total corpus callosum to midline sagittal cerebral area (%)(7.50*0.72 vs. 6.90t0.82 ~(0.05) was significantly smaller In schizophrenia than control group. Conclusion : In this study, we found significant differences in corpus callosum between schizophrenic patients and normal control group.

담도에 국한되어 증상을 유발한 석회쓸개즙 2 예

윤성우,이지영,하경호,이수경,한나,배효근,박선자 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

Limy bile is a rare condition characterized by excessive precipitation of calcium carbonate in the gallbladder or bile duct. Recently we experienced two cases with obstructive jaundice in which limy bile in the common bile duct but not in the gallbladder for one case, and in the common bile duct and intra hepatic duct but not in the gallbladder for another case. The patients were treated by endoscopic sphincterotomy. Here, we report the cases and review the literature.

혼합 과일 발효주의 품질 특성 및 생리기능성

신자원, 한상민, 박원종, 이종수 배재대학교 자연과학연구소 2014 自然科學論文集 Vol.25 No.1

새로운 생리 기능성 과실주를 개발하고자 포도와 사과, 배, 복숭아 등을 이용하여 혼합 과일 발효주를 제조하여 이들의 품질특성과 생리기능성을 조사하였다. 혼합 과일 발효주의 에탄올 함량은 9.6% 이었고 총산함량과 휘발산 함량은 각각 0.73%와 0.086% 이었다. 또한 총 기호도는 신맛과 쓴맛이 살아있고 단맛이 적어 우수하였고 노화억제에 관련된 항산화 활성이 28.2% 이었고 항고혈압성 안지오텐신 전환효소 저해활성이 61.2% 로 우수하였다. To develop a new physiological functional wine, quality characteristics and its physiological functionality of the mixed fruit(Mf) wine were investigated. Ethanol contents of the Mf wine was 9.6%, and total acidity and volatile acid content were 0.73% and 0.086%, respectively. Anti-aging antioxidant activity of the Mf wine was 28.2% and anti-hypertensive angiotensin -converting enzyme inhibitory activity was very high 61.2%.

색상 측정 기기를 이용한 복합레진 적층 수복과 단일 수복의 색상 비교 분석

송영상,김자현,이빈나,장지현,장훈상,황윤찬,오원만,황인남 大韓齒科保存學會 2012 Restorative Dentistry & Endodontics Vol.37 No.2

Objectives: This study analyzed the difference in color caused by different thickness in enamel layer of composite resins when applied with single and layering placement technique, and evaluated if the results agreed with the shade guide from the manufacturers to verify reliability of the color matching process of the manufacturers. Materials and Methods: For single composite resin samples, 6 mm diameter and 4 mm thickness cylindrical samples were fabricated using Ceram-X mono (DENTSPLY DeTrey) and CIE L*a*b* values were measured with spectrophotometer. Same process was done for layering compositie resin samples, making 3 dentinal shade samples, 4 mm thickness, for each shade using Ceram-X duo (DENTSPLY DeTrey) and enamel shade resins were layered in 2 mm thickness and CIE L*a*b* values were measured. These samples were ground to 0.2 mm thickness each time, and CIE L*a*b* values were measured to 1 mm thickness of enamel shade resin. Results: Color difference (△E*) between single and layering composite resin was 1.37 minimum and 10.53 maximum when layering thicknesses were between 1 mm and 2 mm and 6 out of 10 same shade groups suggested by manufacturer showed remarkable color difference at anythickness (△E* > 3.3). Conclusion: When using Ceram-X mono and duo for composite resin restoration, following the manufacturer's instructions for chossing the shade is not appropriate, and more accurate information for Ceram-X duo is needed on the variation and expression of the shades depending on the thickness of the enamel. (Restor Dent Endod 2012;37(2):84-89)

물세척법에 의한 결장루관리 실태에 관한 조사

최상경,박희자,김채숙,서문숙 대한대장항문학회 1992 Annals of Coloproctolgy Vol.8 No.2

위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.

우리나라 重要産業製品 流通構造의 近代化方案

李相道,金正子,宋瑞日,李相玩 동아대학교 공과대학 부설 한국자원개발연구소 1980 硏究報告 Vol.5 No.1

It needs the distributive facilities to perform efficiently the construction of distribution center for the improvement plan of physical distribution structure. In view of promoting distributive modernization and physical distribution cost reduction, the establishment of optimum scale by intensity and concerning of transportation is persued. These efficient arrangements of distribution center which can be organic combining facilities of a supplier and a demander are the urgent challenges. With a view to such distribution problems, the purpose of this paper is to concentrate the presentation of algorithm in selecting the optimal location of distribution center to build model for systematization and to obtain basic data on the design of distribution system in the future.

7종 야생초의 식용화를 위한 조리방법에 관한 연구 : 관능검사를 중심으로

구성자,이경희,이혜정 한국조리과학회 1994 한국식품조리과학회지 Vol.10 No.3

The object of this study was investigation of the appreciable cooking condition in seven wild grasses, an evening primerose(Oenothera lamarckiana Seringe, S₁), a spiderwort(Commelina Communis L. S₂), the flower of a convolvulus(Calystegia Ja-ponica form Vulgaris gaea, S₃), So Ru Jaeng Yi(Portulaca Oleracea, S₄), Shoe Bi Rum(Portulacae Oleracea L, S_5), O Yi Pul(Sanguisorb aOfficinalis, S_6), Jip Sin Na Mul(Agrimonia poisa var. Japonica Nakai, S_7), in order to find out the importance as an useful vegetable. In this work 7 wild grasses with different soaking solutions and boiling conditions were examined to investigation the preference factors by sensory evaluation. Results of sensory evaluation for samples showed a significant difference at 1% and 5% level There were high significant differents in samples boiled for different time about astringent taste, bitter taste, perfume, green color and grassy smell at 1% and 5% level. In cooking methods of 7 samples, Namul was liked best and Guk, Salad and Fritter were followed. The condiments which were used for seasoning Namul were Gochujang, Soy Paste, Salt. Gochujang was most preferred.

동자개(Pseudobagrus fulvidraco)의 난모세포 성숙과 배란에 대한 스테로이드와 HCG의 in vitro효과

백혜자,한창희,임창구 동의대학교 기초과학연구소 1998 基礎科學硏究論文集 Vol.8 No.1

The aim of this study was to determine the effect of steroids and human chorionic gonadotropin(HCG) on in vitro maturation and ovulation of oocyte in Pseudobagrus fulvidraco. Oocytes were incubated in the media Leibovitz L15 supplemented with the various concentration of 17α, 20β-dihydroxy-4-pregnen-3-one (17α20βOHP), 17α-hydroxyprogesterone (17αOHP), progesterone(P₄), estradiol-17β(E₂)and HCG. After 60 hours incubation, the maturation ability of oocyte was assessed by the appearance of germinal vesicle breakdown (GVBD). GVBD was significantly enhanced by the addition of 17α20βOHP, 17αOHP, P₄and HCG(P$lt;0.05). The highest GVBD was observed when 17α20βOHP and HCG were supplemented to media. When oocytes were cultured for 16hours in media containing 10∼1,000 ng/ml 17α20βOHP, 17αOHP and P₄, the rate of GVBD in oocytes cultured in the medium supplemented with 100ng/ml 17α20βOHP (65%) was significantly higher than that with 17αOHP(40%) and P₄(35%). The effects of 17α20βOHP and HCG on GVBD were assessed by various concentration of these hormones. When oocytes were cultured for 60 hours in various media containing 1∼1,000 ng/ml 17α20βOHP or 5∼1,000 IU/ml HCG, the GVBD of oocytes was significantly increased in the medium with 10∼100 ng/ml 17α20βOHP and 500 IU/ml HCG. When oocytes were cultured in the various media supplemented 1∼1,000 ng/ml 17α20βOHP or 5∼1,000 IU/ml HCG for 60 hours, the media with 1∼100 ng/ml 17α20βOHP or 50∼1,000 IU/ml HCG significantly increased in the rate of ovulation. However supplementation with 1,000 ng/ml 17α20βOHP or 5 IU/ml HCG did not improve the rate of ovulation compared to controls. This results indicate that supplementation of steroid and HCG except E₂can improve the in vitro maturation and ovulation of oocyte in P. fulvidraco; HCG and 17α20βOHP may be more effective than other steroids on oocyte maturation and ovulation in P. fulvidraco.

녹차의 주성분인 에피갈로카테킨 갈레이트의 정맥주사후 흰쥐에서의 약물속도론 연구

임재수,황성주,지웅길,김동출 충남대학교 약학대학 의약품개발연구소 2000 藥學論文集 Vol.16 No.-

The pharmcacokinetic study of epigallocatechin gallate was performed following iv bolus administration in Sprague-Dawley rats. The values of systemic clearance (CL) were 68±5 and 27±1 ml/min/kg following iv bolus administration of 1 mg and 5 mg EGCG, respectively. The values of volume of distribution at steady state were 380 and 835 ml/kg body weight after iv bolus administration 1mg and 5mg EGCG, respectively. The decrease in the value of CL and the increase of Vss as a function of dose suggest saturable pharmacokinetics of EGCG in rats.