유두상 에크린 한선종 1예

최현성,이지현,윤석권,김한욱,임철완 대한피부과학회 2004 大韓皮膚科學會誌 Vol.42 No.3

Papillary eccrine adenoma is a rare benign sweat gland neoplasm. It occurs most often as a solitary nodule in women and is located predominantly on the distal portion of the extremities. This tumor is similar to tubular apocrine adenoma in histological and clinical aspects, so distinction of these tumors is still controversial. We report a case of two papillary eccrine adenomas developed on the left popliteal and calf area of a 58-year-old-man, this is the first report of the multiple papillary eccrine adenomas in Korea. (Korean J Dermatol 2004;42(3):353~355)

조깅과 중량운동의 혼합 운동 프로그램이 에너지 소비량에 미치는 영향

한상철,장희정,이수영,이상호,이상현,하민수 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

Since any exercise program is related with health, we cannot but take into consideration the efficiency of fat consumption. This study was aimed at determining the effects of the exercise programs combining jogging and weight training on nutrient-wise energy consumption in order to facilitate consumption of fat during exercise. To this end, 10 male students attending department of sports science of T University located in Incheon were sampled to be subject to exercise programs combining jogging and weight training. The subjects were urged to do weight training before jogging or vice versa. Then, intake of oxygen and output of carbon dioxide were measured after each session to analyze the amount of carbohydrate and fat based on the breathing exchange rate. The results of this study can be summarized as follows; There was found no significant difference of oxygen and calorie consumption between two exercise programs, but carbohydrate was more consumed by weight training after jogging, while fat was more consumed by jogging after weight training. During rest after exercise, more oxygen, carbohydrate, fat and calorie were consumed when weight training followed jogging, and during recovery time, more oxygen, carbohydrate, fat and calories were consumed when jogging followed weight training.

여자 축구 선수들의 등속성 각근력과 무산소성 운동능력의 상관관계 연구

이상현,이용수,이상호,하민수 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

The purpose of this study was to investigate correlation between the isokinetic leg strength and anaerobic exercise capacity from Wingate ergometer test in women soccer players. 30 females soccer players performed two exercise test. Anaerobic exercise capacity variables including peak power(WPP), mean power(WMP), peak anaerobic power(WPAP) and peak anaerobic capacity(WPAC) test were analyzed using Wingte cycle ergometer test(30sec) and isokinetic leg strength variables including peak torque(PT), average power(AP) and set total work(STW) were analyzed using Cybex 770 iskokinetic device(60, 90, 180°/sec, 5, 10, 25repetitions, respectively). Isokinetic leg strength variables was calculated by the mean value of both knee(legt and right). The experimental results from this study are the following: There were a significant positive correlation between WPP and WMP and PT of knee extension in comparison with knee flexion. PT of knee extension at 60°/sec had the highest positive correlation with WPP(r=.789, p=.000). And WMP had the highest positive correlation with PT of knee extension at 180°/sec. Also, there were a significant positive correlation between WPAP and WPAC and PT of knee extension in comparison with knee flexion. WPAP had the highest positive correlation with PT of knee extension at 90°/sec (r=.765, p=.000)and WPAC had the highest positive correlation with PT of knee extension at 180˚/sec(r=768, p=.000). In conclusion, anaerobic exercise capacity using Wingate test had a significant positive correlation with PT of knee extension. However, because little is known about the correct measurement and evaluation the soccer fitness of women soccer players, it is necessary to study about the improvement of various soccer fitness of women soccer players.

SVE와 Bioventing 기술을 이용한 유류 오염 토양의 지중처리

김석현,공성호,김상민,김용수 漢陽大學校 環境科學硏究所 2001 環境科學論文集 Vol.22 No.-

산업의 발달과 함께 유류의 소비가 점점 늘어나고 있다. 그러나 느린 노출 속도와 토양 오염에 대한 관심의 부족으로 유류 오염 지역이 점점 증가 되고 있다. 본 연구에서는 디젤로 오염된 토양에 SVE와 Bioventing 기술의 적용 가능성을 알아 보고자 하였다. SVE와 Bioventing을 차례로 실시하고 주위의 감시정으로부터 VOCs의 농도를 측정하여 오염물의 감소를 확인하였다. 본 현장의 경우 토양 내 모래의 함량이 많아 높은 Air Permeability를 나타내어 SVE 기술의 적용이 용이함을 알 수 있었다. 그러나 높은 Air Permeability로 인한 영향 반경 및 효율의 감소에 대해 추출정 Screen의 축소와 추출압력의 증가 등의 기술이 필요하였다. Bioventing 기술의 적용시 최소 주입 공기량은 3.5∼4.5㎥/h이었고 Bioventing과 미생물 제제를 병용하여 사용하여도 효과적임을 알 수 있었다. 본 현장에서 SVE와 Bioventing 기술의 적용으로 감시정의 VOCs의 농도가 800∼2400ppm에서 20ppm이하로 감소함을 확인하였다. Contamination of groundwater and soils by petroleum hydrocarbons has gained attention lately and caused serious pollution problems. Conventional remedial solutions for petroleum hydrocarbon contaminated soils (excavation and incineration) and groundwater (pump and treat) are expensive and can increase human exposure to contaminants. In-situ SVE or Bioventing, which induce air flow in the subsurface, can be an option that can restore petroleum hydrocarbon contaminated soil quickly, at lower cost, and with minimal health risk. This study investigated whether in-situ SVE and Bioventing can be applied to diesel contaminated soil or not. This study site consists of sandy soil to assure high air permeability. Owing to the high Air Permeability, the technology, such as the diminution of the monitoring well screen and the increasement of extraction presure, is required to control the decreasement of the influential area and efficiency. In the Bioventing technology, the range of a minimal air flow rate is from 3.5㎥/h to 4.5㎥/h. And it is more effective, used with microorganism. In conclusion, Initial level of VOCs of 800-2400ppm dropped to 20ppm after day operation of bioventing.

스트레스 관리 훈련이 대학생들의 A 유형 행동 및 혈압변화율에 미치는 효과

권현용,장현갑,홍성화 한국동서정신과학회 1998 동서정신과학 Vol.1 No.1

본 연구는 스트레스 관리 훈련이 대학생들의 A유형 행동 및 혈압변화율에 미치는 효과를 알아보기 위한 것이었다. A유형 대학생을 고르기 위해, 약 600여명에게 대학생용 JAS와 Framingham TABP를 실시하였다. 두 검사 모두에서 상위 30%에 해당하는 점수을 받은 학생들을 선발하였다. 본 연구의 피험자는 21명이다. 이들은 무선적으로 스트레스 관리 훈련집단, Roskies의 훈련집단, 통제집단에 각각 할당되었다. 스트레스 관리 훈련집단과 Roskies의 훈련집단은 8주 동안 90분씩 실시하였고, 통제집단은 1회의 스트레스 강의만을 받았다. 본 연구의 결과는 다음과 같다. 첫째, 스트레스 관리 훈련집단과 Roskies의 훈련집단은 통제집단보다 A유형 행동(JAS, Framingham TABP)의 유의미한 감소를 보였다. 둘째, 스트레스 관리 훈련집단과 Roskies의 훈련집단 및 통제집단은 풀기 어려운 과제에 직면했을 때, 혈압율의 감소에 있어서 차이를 보이지 않았다. 결론적으로, 스트레스 관리 훈련은 A유형 행동의 감소에는 효과가 있지만, 생리적 반응인 혈압율의 감소에 있어서는 즉각적인 효과가 없었다. This study was designed to examine the effects of stress managenment on reducing Type A behavior and altertation rate of blood pressure among students of college. About 600 students were give JAS Form-T and Framingham TABP, to select Type A students of college. The responses of Type A the college students got score a high rank 30% in all of tests. Subject for this study were 21 Type A students of college. They were ramdomly assigned to the three grooup; Stress management training group, Roskies' s training group, control group. The Stress management training group and The Roskies' s training group received a 90 minute program for 8 weeks, and The Control group receivd only one stress lecture. The results of this study were as follows; First, Compared to Control group, The stress management training group ans Roskies' s training group showed significant reductions in Type A behavior pattern(JAS Form-T, Framingham TABP). Scond, When given the difficult tast, reduction of blood pressure rate was not significamtly different among three group. In conclusion, stress management training had some effectcts on reducing of Type A behavior pattern, but not biological response as blood pressure rate.

학생정신건강검진 시범운영사업에 따른 추진방안

김현정,김윤영,이혜숙,현미나,남동현,김상원,안동현 韓國學校保健學會 2009 韓國學校保健學會誌 Vol.22 No.1

Purpose: The purpose of the study was to·find the strategies of mental health screening in school. Based on the literature review, we discuss the importance of screening students in schools for mental health problems. Methods: Data from the 2008 Korean Mental Health Screening in Schools(2008-KMHSS) are used to estimate the outline of this screening. We administered the questionnaire for satisfaction of 2008-KMHSS for students(N=1,280), parents(N=2,672), school nurses(N=75), teachers(N=685), district personnels(N=6), and mental health center staffs(N=37). Also we interviewed a part of them by telephone and e-mail. And we reviewed the tools and methods for screening students for emotional/behavioral problems. Results: Mental health screening in schools is a very important, yet worrisome, agenda that is in its very early stages. From the 2008 Korean Mental Health Screening in Schools, 9,588 students(12.9%) needed more evaluation in the first stage. Of these, 6,910(72.1%) completed the second stage screening. In this sample, 1,975(28.6%) utilized the mental health services in school or community. 38.3% of students and 43.7% of their parents notified the2008-KMHSS. But only 12.1% of students and 10.9% of their parents dissatisfied with the screening. 9.9% of teachers and 22.7% of school nurses dissatisfied with the screening. Among them the school nurses were mostly dissatisfied, and they complained work burden from KMHSS. Mental health center staffs complained similar issues. The Children's Problem-behavior Screening Questionnaire(CPSQ) and Adolescents' Mental-health & Problem-behavior Screening Questionnaire(AMPQ) were compatible to screen students in schools for mental health problems in first stage. Conclusion: Mental health screening in schools needs careful planning and implementation. For successful mental health screening in schools, several elements need to be considered: careful planning, collaboration, staff training, and integrative mental health programs and services in community or schools.

STRESS성 위궤양 발생기제에 관한 실험적 연구 : 격리성장 동물의 위궤양 발생에 미치는 Dopamine성 물질의 영향 Effects of Dopaminergic Substances on the Stress-induced Gastric Ulcers in Isolated Mice

장현갑,박순권,강성군 한국심리학회 1991 한국심리학회지 생물 및 생리 Vol.3 No.1

본 연구는 스트레스성 위궤양 발생에 미치는 dopamine성 물질의 영향을 검토하고 나아가 격리성장 경험이 위궤양 발생을 억제시키는 효과를 dopamine성 물질과 관련시켜 알아 보기 위한 것이다. Dopamine 전구물질인 L-dapa 투여는 집단동물과 격리동물의 위궤양을 억제하는데 반해 dopamine 수용기 차단제인 haloperidol은 두 집단 동물의 위궤양을 촉진시켰다. 모든 약물 처치 조건에서 격리성장동물의 위궤양 발생이 집단동물에 비해 유의미하게 낮았다. 그리고 L-dapa를 투여 받은 집단성장동물은 haloperidol을 투여 받은 격리성장동물과 유사한 위궤양 발생을 나타 내었다. 이 결과는 격리동물의 중추에서 catecholamine의 기능이 집단동물에 비해 더 활성화되어 있다는 본 연구자들의 이전 연구 결과를 지지하는 것이다. The one purpose of present study was to examine whether dopamine system is involved in the stress-induced stomach ulceration in mice and the other purpose was to show how attenuation of ulcer by isolation-rearing relates to dopamine system, L-dopa treated animals revealed significantly lower ulceration score than that of saline treatment animals, whereas haloperidol treated animals showed higher ulceration score than saline group in both isolation-reared animals and peer-reared animals. Compared with peer-rearing group, isolation-rearing reduced significantly the development of ulcer in L-dopa, saline, and haloperidol treatment. There was a similar ulceration score between L-dopa treated peer group and haloperidol treated isolation group. The results support our previous findings that catecholamine activity is elevated abnormally by isolation-rearing.

격리성장동물에 있어서 공격성의 정도와 위궤양 발생과의 관계

장현갑,박순권,강성군 한국심리학회 한국심리학회지 생물 및 생리 Vol.6 No.1

본 연구는 격리사육에 의한 공격성-지배성의 정도가 스트레스성 위궤양의 발생에 어떠한 영향을 미치는가를 알아 본 것이다. 생후 21±2일에 이유시킨 생쥐(ICR)를 150일간 격리사육한 후 실험적으로 마련한 자극동물에 대한 공격행동의 빈도에 따라 “공격성-무”, “공격성-하”, “공격성-중”, “공격성-상”으로 구분하고, 24시간 후 1시간 동안의 저온-구금 스트레스를 가한 후, 1시간 30분의 휴식기간을 거쳐 위를 추출하여 위궤양 발생정도를 평정하였다. 얻어진 결과는 다음과 같다. 첫째, “공격성-하”집단과 “공격성-상”집단의 위궤양 발생이 동료 동물에 비해 낮았고, 둘째, “공격성-무”집단과 “공격성-중”집단의 위궤양 발생 정도는 동료 동물과 통계적인 차이가 없었으며, 셋째, “공격성-중”집단의 위궤양 발생은 나머지 3개의 격리집단보다 유의미하게 높았다. 따라서 본 연구의 결과는 정서반응을 적절하게 표현하지 못하고 억압하면 신체에 병리적인 결과가 나타난다는 견해나, 분노와 같은 불쾌 정서를 적절하게 표현하지 못하면 위궤양이나 고혈압과 같은 정신신체 질병이 발생될 수 있다는 견해를 지지한다. The purpose of this study was to examine the effects of the aggression and social dominance on stress ulcer in isolated mice. Subjects were ICR strain of mice that were separated from their own litters on the 21st day of life and reared in isolation and in group for 150 days. All animals divided into four groups, "no-aggressiveness", "low-aggressiveness", "middle-aggressiveness" or "high-aggressiveness" on the basis of the frequency of aggressive behaviors to the stimulating animals. Twenty-four hours after aggression rating, animals were exposed to cold-restraint stress for an hour, and then stomach ulcer was estimated under operational microscope. The results were as follows: First, Ulcer scores of "low-aggressiveness" and "high-aggressiveness" group were lower than group rearing animals. Second, "no-aggressiveness" and "middle-aggressiveness" group were not different from group animals in ulcer score. Third, Ulcer scores in "middle-aggressiveness" group were higher than another three isolation groups. The results of this study hold similar views that if the reaction of emotion is suppressed, physical diseases tend to happen or if unpleasure feeling such as anger does not vent, various psychosomatic diseases such as stomach ulcer or hypertension can be induced.

사람 치수 세포와 치주 인대 세포의 유전자 발현에 관한 비교 연구

소현,박상혁,최기운 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.5

The purpose of this study was to characterize functional distinction between human dental pulp cells(PC) and periodontal ligament cells(PDLC) using cDNA micro array assay and to confirm the results of the microarray assay using RT-PCR. 3 genes out of 51 genes which were found to be more expressed(>2 fold) in PC were selected, and 3 genes out of 19 genes which were found to be more expressed(>2 fold) in PDLC were selected for RT-PCR as well. According to this study, the results were as follows: 1. From the micro array assay, 51 genes were more expressed (2 fold) from PC than PDLC. 2. RT-PCR confirmed that ITGA4 and TGFβ2 were more expressed in PC than in PDLC 3. From the micro array assay, 19 genes were more expressed (2 fold) from PDLC than PC. 4. RT-PCR confirmed that LUM, WISP1. and MMP1 were more expressed in PDLC than in PC. From the present study, different expression of the genes between the PC and PDLC were characterized to show the genes which play an important role in dentinogenesis were more expressed from PC than PDLC, while the genes which were related with collagen synthesis were more expressed from PDLC than PC. 본 연구는 사람 치수세포 및 치주인대세포의 차이를 알아보고자 배양한 각각의 세포를 CDNA microarray assay를 통하여 유전자의 발현정도의 차이를 비교하였다. 그 결과를 바탕으로 각각의 세포에서 2배 이상의 유전자 발현의 차이를 보이는 유전자중 특징적인 3가지 유전자를 선택하여 RT-PCR로 검증한 결과 다음과 같은 결론을 얻었다; 1. Microarray assay 결과, 치주인대 세포에 비해 치수 세포에서 2배 이상 발현한 유전자 수는 총 51개가 나타났다. 2. RT-PCR의 결과, 치주인대세포에 비해 치수 세포에서 ITGA4, TGF-β2 등이 높게 나타났다. 3. Microarray assay결과, 치수 세포에서 비해 치주인대 세포에서 2배 이상 발현한 유전자 수는 총 19개가 나타났다. 4. RT-PCR의 결과, 치수 세포에 비해 치주인대세포에서 LUM, WISP1, MMP1 등이 높게 나타났다. 본 연구 결과로 치수세포에는 상아질 형성에 관여하는 특징적인 유전자가 치주인대세포에 비해 높게 발현되었으며, 치주인대세포에는 교원질 합성에 관여하는 특징적인 유전자가 치수세포에 비해 높게 발현되어, 치수세포와 치주인데 세포는 유전자 발현의 차이가 나타남을 알 수 있었다.

기포부상분리법에 의한 Cu(Ⅱ)의 제거에 있어서 유동특성에 관한 연구

김현수,박주량,이승무 연세대학교 산업기술연구소 1985 논문집 Vol.17 No.1

This investigation was carried out to study the dynamic characteristics of the removal of Cu(II) from wastewater by the technique of foam fractionation, using sodium-dodecylbenzenesulfornate (DBS) as a foaming agent. The surface excess concentration of Cu(II) with the change of DBS concentration in feed solution and superficial gas velocity was obtained by measuring foam diameter. The value of HTU with the change of DBS concentration and superficial gas velocity was determing by measuring superficial liquid velocity. The experimental results are obtained as follows: 1. When Cu(II) concentration in feed solution is constant, the surface excess concentration of Cu(II) increased as DBS concentration increased. But decreased as superficial gas velocity increased. 2. Equilibrium constant (Tcu/Cw) between the surface excess concentration of foam and the concentration of interstitial liquid increased as DBS concentration in feed solution increased. However it was not affected by the change of superficial gas velocity. 3. For the superficial gas velocity above 10cm/min, the empirical equation was derived as follows: HTU = 2 exp [0.642(??) - 0.19(??)] where, C??(DBS) denotes the DBS concentration in feed solution, and v is the superficial gas velocity.