알쯔하이머성 치매의 언어정보처리과정 특성 연구

변선경,정옥란 대구대학교 특수교육재활과학연구소 2004 再活科學硏究 Vol.22 No.1

알쯔하이머성 치매는 신경 화학적 구성, 뇌조직의 변화에 의해 특성 지어지는 진행성으로 퇴행하는 질병이며, 사실적 지식의 계층적 구조화된 체계, 의미기억의 중요한 손상을 보여준다. 알쯔하이머성 치매환자의 어휘-의미장애의 특징을 의미-범주과제를 이용한 연합성과 의미범주를 통해 연구하였다. 연구대상은 치매집단을 중증도에 따라 세 집단으로 분류한 뒤, 각 9명씩 27명으로 하였다. 연구결과 범주에 따른 연합성 이해 차이에는 유의미한 차이를 나타내지 못했다. 치매의 정도에 따른 연합성 이해는 유의미한 차이를 보였다. 이러한 결과는 치매의 의미적 결함은 범주보다는 연합성에 결함이 있다고 볼 수 있으며, 이는 어휘-의미수준의 손상의 결과라고 볼 수 있다. The goal of this paper was to address 2 issues relevant to the semantic impairment in Alzheimer's disease: (1) stimulus associative effects (2) semantic category effects (contrasting living with non-living categories). The subjects of this study were divided into 3 groups based on K-Mini Mental state Examination (K-MMSE) scale: probable AD, mild AD, and moderate AD group. Twenty-seven patients with AD were given a semantic category task. The response were analyzed by one-way ANOVA to determine any significant difference among 3 groups. The result of this study revealed the following findings: (1) semantic category effect didn't a difference influence semantic association, (2) The AD group showed a significant on semantic association, (3) There was a significant correlation between the AD group and semantic association. In sum, the present results indicated that semantic impairment in AD involved a progressive deterioration of lexical-semantic representation.

천안 순천향병원 입원환자의 와포자충 난포낭 감염율

이옥란,이선화 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

From March 1998 to December 1999, 497 stool samples from inpatients with various disease in several departments of Chunan Soonchunhyang hospital were examined for the prevalence of Cryptosporidium. Stool samples were stained by a modified acid-fast technique for oocyst of Cryptosporidium. In results, Cryptospridium oocysts were found in 76 of 497 stools by modified acid-fast staining technique. The prevalenve was 15.29%. The prevalence of Chungcheongnamdo that hold to 91.35% of examined stools was 15.29%. The prevalence was 13.98%(33/236) in chunan, was 16.5%(36/218) in other chungnam areas except chunan. By age groups, the prevalence was more higher in sixties~seventies age groups than to that other age groups. By sex, the prevalence were more higher in male than female in age groups before forties, and were more higher in female in age groups after fifties. Consistency(diarrhea, semi-solid, solid) of stools were not associated with Cryoptosporidium positive rates. In conclusion, it was considered that the prevalence of Cryptosporidium was spreading in all over the chungcheongnamdo.

경기도 안성군내 초등학교 학생들의 요충감염 양상

이선화,이옥란,남해선 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

We examined the prevalence rate of Enterobius vermicularis infection by single examination of cellotape anal swap for 658 children of 4 primary schools and attatched kindergartens in Ansung of Korea in June, 1996. The total positive rate was 12.9%, and that of female children(15.9%) was higher than male(10.0%). Treatment was achieved by three different ways with albendazole 400 mg as a total. Six months later, follow-up examination was done. Overall egg positive rate of follow-up study was 6.8%. The change of egg positive rates between first and follow-up examination of each group were as follows: 1. A group of single medication for egg positive children only : 13.3% to 7.5% (reduction rate, 43.6%). 2. A group of single medication for all individuals in a class : 9.2% to 4.6% (reduction rate, 50.0%). 3. A group of twice medication at an interval of 20 days for all individuals in a class : 19.3% to 8.6% (reduction rate, 55.4%). These results suggest that medication of albendazole of every six months may be reduce the egg positive rate of Enterobius vermicularis remarkably, especially the group that has relatively low prevalence rate of enterobiasis.

흰쥐 간장 내 일록춘폐흡충의 충낭 1례

이옥란,이선화 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

The ectopic infection except lung of Paragonimus species are frequent occurrence, but the liver rare involved as a site of ectopic Paragonimiasis. There are not reported till now for liver invasion of Paragonimus iloktsuenensis. This is a report that we have observed a case of the ectopic liver infection of P. iloktsuenensis in an experimental infected albino rat. As a rat among 1,017 rats that were experimented infection with P. iloktsuenensis during 13 years(1989~2001) in the department of Parasitology in Soonchunhyang Medical College, the rat was experimentally infected with 70 excysted metacercariae of P. iloktsuenensis through oral route, was autosied on sixth week after infection, At autopsy of the rat, 7 cysts contained two worms in each cyst was detected in lung and a cyst were detected in live as ectopic site. The cyst lesion in the liver was located inside the right lobe of the liver that was a slightly protrudent domeshaped lesion about 10mm in maximum dimensions. In excision of the cyst, two viable worms of P. iloktsuenensis was reside in well developed cyst wall that was surrounded with numerous leukocytes and thick fibrous tissues. These two worms were adult worms that were measured with size of 7×4.3mm and 9×4.1mm respectively and were well developed ovary, testis, vitellaria and uterus on Semicon's Acetocarmine staining. Two adult worms of P. iloktsuenensis in ectopic liver syst of alvino rat was developed as same as development in lung. We supposed that the route of ectopic liver infection was assumed to be a direct invasion during larval migraton from intestine to lung of albino rat.

국내산 무화과를 이용한 와인 제조 및 품질 개선 효과

정미란,차정단,윤순일,한종현,이영은 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.1

Fig(Ficus carica L.) which belongs to Moraceae family has been used as digestion promoter, cure for ulcerative inflammation and eruption in Korea. Figs have very short preservation period and can be kept only 1 week even in the refrigeration system. The possibility of wine-making from Korean figs was tested by analyzing the fermentation characteristics, proximate analysis and free sugar contents of wine made of slices with 20% sugar addition. Ethanol fermentation of the figs by Saccharomyces cerevisiae was done rapidly. The ethanol contents, pH, total acidity and sugar content were 12.1%, 3.91, 0.42% and 9.9 °Brix, respectively. The results from the sensory evaluation were as follows. The wine made from the sliced figs were better than that from fig juices in their sensory scores. The wine made with frozen figs was not different from that made with fresh ones. To improve the quality of wine, the addition of dried leaf powder in the concentration of 100 ppm were tried and found it was superior to the one made without leaf.

독서요법이 초등학생의 자아존중감 향상에 미치는 효과

추정선,김해란 부산교육대학교 교육대학원 2003 논문집 Vol.5 No.-

The purpose of this study was to examine the effects of bibliotherapy on the improvement of elementary school children's self-esteem. For this purpose, the following hypotheses were set up. Hypothesis Ⅰ. The bibliotherapy would have a significant effect on the improvement of elementary school children's global self-esteem. Hypothesis Ⅱ. The bibliotherapy would have a significant effect on the improvement of elementary school children's social-peer self-esteem. Hypothesis Ⅲ. The bibliotherapy would have a significant effect on the improvement of elementary school children's home-parents self-esteem. Hypothesis Ⅳ. The bibliotherapy would have a significant effect on the improvement of elementary school children's school-academic self-esteem. To verify these hypotheses the self-esteem test was conducted for 4th grade 3 classes(103 children) from H elementary school located Busan city. And 20 elementary school children were selected. Each participant was assined to ither an experimental or a control group. Experimental group is consisted of 10(8 males and 2 females) elementary school children. The experimental group received the bibliotherapy, a session for 60 minutes. 2 times a week, 12 session in all. No treatment was given to the control group. As soon as experimental group finish up the bibliotherapy. the experimental and control group were given post-test. After 2 weeks the experimental group were given delayed-test. The contents of the biblioherapy put in this study were reconstructed referring to bibliotherapy program of Watson(1994), Choi Sun-Hee(1997)by the researcher's intention for the study. The instrument used to verify the effects of bibliotherapy was Self-esteem. Inventory developed by Choi Bo-Ga and Jeon Gwee-Yeon(1993). Manipulation and analysis of data was used by computer, using SPSS/PC+ (version11.0). The t-test was applied to post-test of the experimental and the control group, pre-post test of each group, and post-delayed test of the experimental group. The results of this study are as follows : First, the bibliotherapy had a significant effect on the improvement of elementary school children's global self-esteem. Second, the bibliotherapy had a significant effect on the improvement of elementary school children's social-peer self-esteem. Third, the bibliotherapy had a significant effect on the improvement of elementary school children's home-parents self-esteem. Forth, the bibliotherapy had not a significant effect on the improvement of elementary school children's school-academic self-esteem. The fifth. the effects of bibliotherapy on the improvement of elementary school children's global self-esteem, social-peer self-esteem and home-parents self-esteem were maintained after 2 weeks.

원료콩의 증자조건을 달리한 검정콩 간장의 유리당, 유기산 및 지방산의 변화

권선화,최재훈,고영란,손미예,박석규 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

콩의 증자조건에 따른 검정콩 전통간장의 숙성 후 유리당, 유기산, 지방산조성을 조사하였다. pH 값은 5.04~5.32로 시험구간의 큰 차이를 나타내지 않았고, 원료 콩을 상압증자한 검정콩 간장이 가압이나 스팀보다는 약간 높은 수치를 나타내었다. 적정산도는 4.26~7.73mL로 나타났으며, 가압증자한 검정콩 간장(4.26~5.61mL)이 가장 높았으며, 다음으로 상압(7.32mL), 스팀(5.99~6.96mL)의 순으로 나타났다. 환원당은 25.18~194.81㎎%로 나타났고, 상압이 25.18㎎%로 가장 낮았으며, 가압이나 스팀증자한 검정콩 간장의 경우 상호간에는 큰 차이가 없지만, 상압한 것보다는 7~8배 높은 함량을 나타내었다. 주요 유리당은 glucose, fructose, xylose였으며, 스팀증자한 검정콩 간장이 상압이나 가압보다 각각의 유리당 모두가 많았고, 상압증자는 유리당이 극히 미량으로 검출되었다. 주요 유기산은 succinic acid, oxalicaicd, tartaric aic, malic acid, citric acid였고, 총 유기산은 스팀증자 (40.38~76.96 ㎎%)한 검정콩 간장이 상압(55.85㎎%)이나 가압(27.78~34.21)한 것보다 많았다. 증자 처리시간이 길수로 가압과 스팀으로 처리하여 제도된 검정콩 간장은 약간씩 감소되는 경향을 나타내었다. 주요 지방산은 palmitic acid(33.28~43.51%), stearic a창(14.15~19.16%), myristic acid(5.03~19.14%)였으며, 전체 지방산 중에 55.97~72.85% 비율을 차지하였고, 원료 콩에 존재하지 myristic acid가 상당히 많이 존재하였다. pH values in all samples were in the range of 5.04 to 5.32. pH of kanjang prepared with normal pressure(HPK) was higher than that of kanjang prepared with high pressure(HPK) and kanjang prepared with steam(SPK). Titratable acidity(TA) in all samples were found to be 4.26∼7.72 mL. TA in HPK(5.99∼6.96 mL) was lower than that in SPK(4.26∼5.61 mL) and NPK(7.32 mL). Reducing sugar(RS) contents in all samples were in the range of 25.48 to 194.81 ㎎%. Rs contents of HPK and SPK were a similar pattern and were higher than that of NPK. Major free sugars(FS) were glucose, fructose and xylose. In total FS, SPK was higher than that of NPK and HPK. Major organic acids(OA) were succinic acid, oxalic acid, tartaric acid, malic acid citric acid. OA contents in HPK and SPK were decreased slightly according to the heating time of whole black bean. The highest percentage of fatty acid(FA) in all samples was palmitic acid(33.28∼43.51% as area % of GC chromatogram), followed in a decreasing order by stearic acid(14.15∼19.16%) and myristic acid(5.93∼19.14%). The composition ratios of three FA to total FA ranged from 55.97 to 72.85%. In all samples, there was myristic acid that was not contained in raw soybean.

Adriamycin 투여가 흰쥐 상아질 형성에 미치는 영향에 관한 연구

이상열,김선헌,최홍란,이은주 전남대학교 치과대학 1992 전남치대논문집 Vol.4 No.1

In order to study the toxic effect of adriamycin on the formation of dentin of the rat, adriamycin(5㎎/㎏ body weight) was injected intravenously, and animals were sacrificed at 1, 3, and 10 days after administration. In the light micrographic observation, aggregation of densely stained cells were observed along the wall of the pulp canal and the odontoblastic layer disappeared after 1 and 3 days. The predentin was not even thickness and irregular in boundary compared to normal predentin. The formation of osteodentin, which has cellular inclusions in the matrix, was noted after 10 days. Electron microscopic observation revealed that the cells in aggregation had long slender cytoplasmic processes and contained more profiles of endoplasmic reticulum and secretory granules. The odontoblasts showed degenerative changes such as cytoplasmic vacuolation and fragmentation of rEr. The cells in the osteodentin and on the surface of irregular osteodentin contained dilated cisternae of rEr and secretory granules. Some cells showed necrotic and degenerative changes. There were no odontoblastic processes and dentinal tubules in the osteodentin matrix, central region of which was densely packed with collagen fibers. It therefore appears that osteodentin formation was observed in the pulp of root canal after adriamycin administration and it is the result of an abnormal differentiation of pulp mesenchymal cells.

악골에 발생한 악성 섬유성조직구종 2례

정종철,최홍란,오희균,박준아,류선열,이종호,김영운,정숭룡 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3

Malignant fibrous histiocytoma rarely occurs in the jaws. Although the histogenesis of this tumor remains controversal, it is best regarded as a primitive and pleomorphic nature reflected by collagen production and occasional phagocytosis. It is common for metastatic foci to appear in lung and regional lymph node. There are variable treatments such as radiotherapy, surgical excision or combination, therapy of surgical excision, chemotherapy and radiotherapy. With the review of literatures, the authors report the clinical study of two cases of malignant fibrous histiocytoma of the jaw.

유통정보시스템의 효율적 구축방안에 관한 연구 : 부산·대구지역을 중심으로 Focusing on the Sales Business in Pusan-Taegu

李奎煥,朴善泰,金香蘭 대구산업정보대학 1998 논문집 Vol.12 No.1

This study aimed first to correctly understand informationalization of distribution, that is POS System, EDI, EOS, and distributing VAN, second to observe the present condition and preceeding examples of construction of informationalization of distribution in our country and to execute analysis of corroborative evidence regarding informationalization of distribution centered on distributing companies in Pusan and Taegu districts, third to grasp the impeding primary factors when informationalization is built up, and fourth to present effective building up lans of informationalization of distribution in Pusan and Taegu districts which will be the foundation of informationalization of distribution in the distributing business circles. The writer studied, for the method of study, by dividing into theoretical study, research portion of the present condition and preceeding examples of building up informationalization of distribution, and analysis of corroborative evidence. For the theoretical study portion and analysis examples, the study method by documentary records was applied, and domestic and foreign books, theses and periodicals related to the informationalization of distribution were consulted. For the analysis of corroborative evidence, the writer studied by questionaires regarding opening of distributing markets, distriubuting environment and distributing information system of the distributing market by the retail dealers as its objects, and selected research by questionaires to collect information by personally visiting each company. About 15 universities and junior colleges related to the distributing industry in our country produce about 1,280 of fundamental manpower related to distrribution every year, and a portion of large-sized distributing companies established and are managing even inter-company colleges, but it is the real situation that these are not sufficient in quality and quantity. In order to cultivate manpower specialized in distribution, the industry, universities and government, forming a trinity, should cope with the matter jointly, and especially, the government level should newly establish subjects of study related to the distribution drastically and political and financial support should be necessarily followed. Also, if POS system is induced, as the source of tax revenue is completely exposed, compared with those companies which do not induce POS System, they will suffer disadvantage, so preferential treating method is necessary in case of application of valued added tax or income standard. The customary practice of dealing without data harmful to normal commercial transaction order and against equity is pointed out as the most fundamental problem point being held by the distributing business circle in our country. For the sake of effective building up the distributing information system, the source making rate shall be raised, the ratio of domestic made instruments of POS System shall be increased, by developing EOS System which can be connected with manufacturing companies, POS System shall be utilized effectively by connecting with the management information system of the whole enterprises, EIS (Executive Information System) and various data base, and shall be connected with EOS with other components of distributing channel and EOS and EFT (Electronic Fund Transfer) system shall be connected through EDI or VAN. Such distributing information system can accomplish composite distribution information systematization, so it can promote greatly the management power not only of distributing business but manufacturing business.