A Structural Model of Intra-Organizational Diffusion of Information Technology: Firm's Database System Adoption

hyun,jung suk 한국산업경영시스템학회 1999 한국산업경영시스템학회지 Vol.22 No.53

男性不育 因子(Male factor infertilily)인 異常精子症(OATS: Oligo-AsthenoTeratoSpermia) 患者에게 補賢益精 爲主의 韓藥投輿에 依한 臨床的 考察

Yook, Hyun-Suk 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Hyun-Suk Yook. Department of Oriental Internal Medicine, Conmaul Oriental Hospital, Seoul, Korea. The Clnical Research on the Effects of Therapy of 補腎益精 (BOSHINIKJUNG) in Male factor infertility (OATS:Oligo-Astheno-TertoSpermia). Proceedings of International Symposium on East-West Medicine, Seoul. 90-109, 1999.-Semen Analysis has been used as a basic, essential and important tool to evaluate the male infertility. The proportion on Male factor infertility due to quantitative and qualitative sperm disorders is about 50-60% in infertile couples. Although the proportion of Male factor infertility is high, the studies and trials are too weak, and the treatment of couples with male factor infertility mostly depends on Female treatment. Semen analysis can be divided into concentration, motional and morphological analysis of sperm. Sperm has very complicated and waried motional characteristics, but the motility is accepted as the most important parameter. There is no absolute fertile semen parameter, but recently most andrologist agree that the Total Motile Sperm Count might be the most important evaluation of male reproductive ability. This clinical research was performed in order to evercome and compensate for conventioal Western Medicine, and to investigate the effects of the Oriental Medical treatment method(補腎益精, Boshinikjung)on male factor infertility due to quantitative and qualitative sperm disorders(OATS:Oligo-Astheno-TeratoSpermai).The effects of the Oriental Medical treatment method(補腎益精, Boshinikjung) on the male factor infertility, OATS(Oligo-Astheno-TeratoSpermai) were analyzed objective, precise, accutate by CASA(Computer-Aided Sperm Analysis)for Semen Volume(VOL), Sperm Concentration(CON), percent Motility(MOT), Velocity of Curvilinear Line(VCL), Velocity of Straight Line(VSL), Velocity of Average Path(VAP), Linearity(LIN), Amplitude of Lateral Head displacement(ALH), Percentage of Hyperactivated sperm(HYP), and Total Motile Sperm Count compared with pre-treatment baseline values. The results showed that CON,MOT,VCL,VSL,VAP,LIN,ALH, HYP were improved, and Total Motile Sperm Count was significantly improved between the pre-treatment and post-treatment. I think that more research should be progressed into the mechanism of the Oriental Medical treatment method(補腎益精, Boshinikjung) on the male factor infertility due to quantitative and qualitative sperm disorders. Hereafter it will be necessary to study both oriental and western medical treatments within the interchangeble random arms of experiments with the same conditions, throught the comparative research like this study. In conclusion, it is evident that if Oriental-Western Medical collaborated treatments like herb medication and surgical operation are performed at the same time, a progressive step toward male factor infertility will be achieved.

남녀 대학생의 콜레스테롤 섭취실태

현태선,김화숙,김현숙,연미영 충북대학교 교육생활연구소 2001 생활과학연구논총 Vol.4 No.-

A dietary surrey with 24-hour recap 1 method was conducted in order to assess cholesterol intake of college students. The subjects of this study were 33 male and 47 female students in Chungbuk National University. Nutrient intakes were calculated using DS24 program with a new cholesterol database updated in Seoul National University. Average cholesterol intakes of male and female students were 332.3mg and 329.3mg, respectively. These values were much higher than the other cholesterol intake data of the previous studies as well as the recommended level, that is, no more than 300mg. Foods contributed to cholesterol intake of the subjects were eggs, frozen dumplings, common squid, pork, chicken, anchovy, milk, in the order. Average cholesterol intakes of the subjects according to some factors affecting nutrient intake were analyzed. Among the factors, resident type, interest in diet, and nutrient in caution were affected on their cholesterol intake, The average intake of self-cooking students was significantly higher than that of home-living students. And the lower the interest in diet was, the higher the average intake was. The average intake of the students who responded that they were concerned about fat or cholesterol was actually higher than that of the other group. These results emphasize the need for nutrition education directed at having attention to their diet and decreasing cholesterol intake through food selection or food preparation, especially to self-cooking students. In addition, to validate the new cholesterol database, cholesterol intake should be further assessed among a variety of groups.

유아 과학교육 활동을 중심으로 한 수와 사회교육 통합 사례 분석

김숙자,현금자 한국영유아보육학회 2004 한국영유아보육학 Vol.0 No.38

본 연구의 목적은 과학활동을 중심으로 한 수와 사회 통합 교육 활동 수업 사례에서의 유아 반응을 분석하는 것이다. 분석 대상은 충북지역 M유치원 만 5세 유아 5명의 활동 수업 사례들이다. 「물」을 주제로 하여 총 10회 이루어진 교육활동은 선행연구(김숙자.김현정, 2003)에서 제시한 교수-학습과정 기본 모형을 토대로 하여 동기유발 단계, 초기개념 단계, 교수매체 투입, 개별 실험과 소그룹 토의를 통한 확장개념, 심화개념 단계로 재구성 하여 이루어졌다. 분석 결과 초기개념의 단계에서는 물을 옮길 수 있는 물체 예측을 통한 분류 개념과 물을 담는 용기의 높이와 물의 양과의 관련성이 분석되었다. 확장개념의 단계에서는 수 관련 개념으로 분류 개념, 수세기, 순서 짓기, 서수 개념, 높이, 크기, 길이, 양, 무게의 측정개념이 분석되었다. 사회 관련 개념은 문제해결을 위해 토의, 실험하기가 계속 순환되는 과정을 통해 나타난 협동하기, 다른 사람 의견 존중하기의 사회관련 개념이 분석되었다. 심화 개념의 단계에서는 물의 양과 물이 흘러나오는 속도, 물체의 형태변화와 부력의 관련성, 가라앉는 물체를 뜨는 물체에 올려놓는 위치와 부력의 관련성이 분석되었다. The purpose of this study was to analyze teacher's teaching-learning strategies and young children's responses to the science integrated study with mathematics and social studies for young children, based on the basic process model of teaching-learning. The basic process model of teaching-learning is a remodeling which is basic process model of teaching-learning. This was researched by Kim, Suk Ja;Kim, Hyun Joung(2003). To achieve this purpose, actual class episodes were analyzed. The episodes from the classes were derived from 10 sessions of interaction between teacher and 5 kindergarten children. With priority given to scientific activities, educational activities were integrated into mathematics, science and social study. The subject of scientific activities was water. Contents of activities were organized with activities to understand concepts of the volume of water and the velocity of water flow. A qualitative analysis was used to access responses of young children to teaching-studying strategies of teachers in case studies. As a result, young children could have their own scientific ideas about the volume of water, the relationship between volume of water, velocities of water flow, and buoyancy. They could understand the concept of mathematics in ractical exercise. By repetitions of experiments and discussions to solve problems, young hildren could realize the concepts of sociality such as cooperating with each other and respecting other people's opinions.

Methylation Status and Expression of E-cadherin in Oral Squamous Cell Carcinomas Compared to Benign Oral Epithelial Lesions

Son, Hyun-Jin,Chu, Jung-Youb,Cho, Eui-Sic,Lee, Dong-Geun,Min, Myung-Gee,Lee, Suk-Keun,Cho, Nam-Pyo The Korean Academy of Oral Biology 2006 International Journal of Oral Biology Vol.31 No.2

Expression of invasion/metastasis suppressor, E-cadherin, is reduced in many types of human carcinomas. Although somatic and germline utations in the CDH1, which encodes the human E-cadherin, have frequently been reported in cases with diffuse gastric and lobular breast ancers, irreversible genetic inactivations are rare in other human carcinomas. Recently, it has been well documented that some genes in human cancers may be inactivated by altered CpG methylation. Herein, we determined the expression and methylation status of E-cadherin in oral squamous cell carcinoma (SCC) by immunohistochemistry and methylation-specific PCR. The expression of E-cadherin was significantly higher in the well-differentiated oral SCCs than the moderately or poorly differentiated ones. None of eight tested benign pithelial hyperplasias showed aberrant methylation, whereas five of 12 oral squamous cell carcinomas showed aberrant methylation. When we compared E-cadherin expression with methylation status, oral SCCs with normal methylation showed a higher expression of E-cadherin than those with methylation. These findings suggest that aberrant CpG methylation of CDH1 promoter region is closely associated with transcriptional inactivation and might be involved in tumor progression of the oral mucosa.

내동정맥루술후의 수지운동이 동정맥루의 혈류와 개존에 미치는 영향

신현석,조원현,이성문,우성구,김현철 大韓脈管外科學會 1995 大韓脈管外科學會誌 Vol.11 No.1

잠수장비와 수중환경에서 나타난 스쿠버 다이버들의 교육불이행

임현수(Lin, Hyun-Soo),강은석(Kang, Eun-Suk) 한국체육과학회 2011 한국체육과학회지 Vol.20 No.5

This study is to follow the studies, which were conducted in Moon island between July and October in 2010. The previous studies, which were conducted by Lim, Hyun-soo and Kang Eun-suk in 2010, studied the current status of education of divers by classifying it into five subjects such as diving science, diving equipment, diving safety, underwater environment, and diving activities through FGI of expert groups. Being aware of the lack of materials about the observation of non-fulfillment of education on diving equipment and underwater environment and interviews, we made visits to the spots where the previous studies were conducted between July 28 and August 2nd to newly add up materials on interviews and questionnaires and analysed the cause and problems of the educational non-fulfillment about diving equipment and underwater environment. The educational non-fulfillment about diving equipment resulted in inappropriate management of equipment and loss of equipment, immature assembly of equipment of equipment, the loss of waist belts, and diving knife"s inappropriate use. The educational non-fulfillment about underwater environment brought about the damage of underwater environment, panic by underwater environment, conflicts with fishing villages, and the problems of trash-littering and defecation.

축구선수의 Detraining과 Retraining이 혈청지질 및 호르몬농도에 미치는 영향

정정화,박재현,채종훈,성혜련,황지인,윤미숙,노금선,윤종관,윤영학,노순덕,정경숙,박일규,김은희,박현태,박상갑 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

The purpose of this study was to investigate the effects of detraining and retraining on serum lipid and hormones in soccer players. Subjects were seven male high-school soccer players. V˙O_2max was determined for each subjects by administering a treadmill test(initial speed: 90m/min, grade: 5%, increasing speed per 3 min: 30m/min). Serum lipid(T-C, TG, HDL-C LDL-C) and hormones(epinephrine, norepinephrine, growth hormones, cortisol) were assayed pre and post detraining in 10, 20, 30 days after retraining. The repeated ANOVA was used to determine significant differences. The 0.05 level of significance was as critical level for the study. The results of the study were as follows: 1. V˙O_2max(ml/min) were 3576.3±204.2ml/min pre detraining, 3234.1±198.9 ml/min post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/min) were 3601.4±170.9 ml/min. There were significantly(p<.05) increased in retraining periods. 2. V˙O_2max(ml/kg/min) were significantly(p<.05) decreased from 62.3±2.9 ml/kg/min to 55.9±4.7 ml/kg/min in detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/kg/min) were 62.4±3.4ml/kg/min, 62.7±2.3ml.kg/min, 67.3±7.2ml/kg/min respectively. There were significantly(p<.05) increased in retraining periods. 3. T-C were significantly (p<.05) increased from 166.6±8.5mg/dl to 175.3±10.3 mg/dl in detraining. In 10, 20, 30 days after retraining, T-C were 160.1± 3.2mg/dl, 156.7±3.7mg/dl, 140.3±9.0mg/dl. There were significantly(p<.05) decreased in retraining periods. 4. HDL-C were 61.4±6.6mg/di pre detraining, 5.3±6.6mg/dl post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, HDL-C were 56.9±7.1mg/dl, 56.4±9.2mg/dl, 57.7±9.1mg/dl respectively. There were no significant difference in retraining periods. 5. The hormones(epinephrine. norepinephrine, growth hormone, cortisol) were changed as same patterns. Epinephrine were 26.0±7.0[g/ml pre detraining, 24.6±3.2pg/ml post detraining. In 10, 20, 30 days after retraining, epinephrine were 26.9±5.6pg/ml, 30.6±6.2pg/ml, 29.4±5.6pg/ml respectively. There were no significant difference in retraining periods. In conclusion, HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were decreased, T-C, LDL-C and TG were increased in detraining. But HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were increased, T-C, LDL-C and TG were decreased in retraining.

김치에서 분리한 Lactobacillus sp. JC-7과 Lactobacillus acidophilus 88간의 Electrofusion 최적조건 설정

조영배,최현정,백형석,전홍기 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

김치 발효 숙성기간을 연장하고 신선도를 오랫동안 유지 할 수 있는 김치발효 starter의 개발을 목적으로 최적숙성기에 있는 김치로부터 bacteriocin생성능이 없는 유산균을 분리하여 동정하였으며, bacteriocin생성능이 우수한 L.acidophilus 88을 융합시키기 위해 electrofusion에 대한 최적 조건을 검토하였다. 분리균주는 Lactobacillus속으로 동정되어 Lactobacillus sp. JC-7이라 명명하였다. Electrofusion에 의해 생성된 융합주를 식별하기 위해 streptomycin(2.5㎎/ml)에 내성을 나타내는 Lactobacillus sp. JC-7변이주와 kanamycin(600㎍/ml)에 내성을 나타내는 L.acidophilus 88변이주를 분리하였다. Electrofusion을 100V/㎝, 120msec(72ohms,1670 capacitance) 에서 수행했을 때 융합효율이 가장 양호하였으며 전기장의 세기와 시간이 중가할수록 융합 효율이 현저히 감소하였다. 2가 양이온은 농도가 중가할수록 대체적으로 융합효율을 감소시키는 경향을 나타내었으나 1mM MGCl_2에서는 대조군에 비해 융합효율이 약간 증가하였다. PEG매개에 의한 융합법의 융합효율을 비교한 결과, 융합효율은 chemical fusion<electrofusion<electrofusion+20% PEG순을 나타내었다. Evaluation of Optimum Conditions for the Electrofusion between Lactobacillus sp. JC-7 Isolated from Kimchi and Lactobacillus acidophilus 88. Young-Bae Jo, Hyun-Jung Choi, Hyung-Suk Baik and Hong-Ki Jun*. Department of Microbiology, Pusan National University, Pusan 609-735,Korea-A lactic acid bacterium was isolated from kimchi. The isolated strain was identified as the genus Lactobacillus thrugh its morphological characteristics and named as Lactobacillus sp. JC-7. The optimum conditions for the electrofusion between streptomycin(2.5㎎/ml)resistant mutant of Lactobacillus acidophilus 88 and kanamycin(600㎍/ml) resistant mutant Lactobacillus sp. JC-7 were evaluated. The highest number of fusants were obtained at a capacitance value of 120msec(1670㎌), a field strength of 100V/㎝,and a pulse controller setting of 72Ω. The potimum pH of elecroporation buffer was 7.5 and the concentration of divalent cation was 1mM MG^2+. Electrofusants were efficiently obtained by addition 20% polyethylene glycol to electroporation buffer. The yield of fusion was better than that of using polyethylene glycol mediated chemical induction.

악성흑색종과 양성멜라닌세포성모반에서 bcl-2 단백발현에 관한 면역조직화학적 연구

이성열,이종석,김현조,정현,조현듯,김의한 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background: The bcl-2 protein, contrast to p53, has been shown to be suppress the apoptosis, and overexpression of the bcl-2 protein has been reported in several malignant tumors. Although how the bcl-2 protein takes part in tumorigenesis has not been proved, the bcl-2 positive tumors appeared to have good prognosis in some malignant tumors. The expression pattern of the bcl-2 in melanocytic nevi and malignant melanoma have not been well known. The authors analyzed immunohistochemically expression of the bcl-2 protein to investigate the role of the bcl-2 protein in developing malignant melanoma. Method: 10 malignant melanoma and 10 benign melanocytic nevi were immunostained with anti-bcl-2 monoclonal antibody. Results: In malignant melanoma, 1 case was 2+ positive, 9 cases were 3+ positive. In benign melanocytic nevi, 2 cases were 2+ positive, 8 cases were 3+ positive. Conclusion: Bcl-2 protein is expressed by benign melanocytic nevi and malignant melanoma. There is no difference of bcl-2 protein expression in melanocytic nevi and malignant melanoma.