Identification and Functional Characterization of Porcine XBP-1 in PEF Cells

Jin-Yu Zhan9,Kyu-Sun Lee,Ji-Su Kim,Kyung-Kwang Lee,Kweon Yu,Deog-Bon Koo 한국동물번식학회 2008 Reproductive & Developmental Biology(Supplement) Vol.32 No.2s

Identification and Functional Characterization of Porcine XBP-1 in PEF Cells

Jin-Yu Zhan9,Kyu-Sun Lee,Ji-Su Kim,Kyung-Kwang Lee,Kweon Yu,Deog-Bon Koo 한국동물생명공학회(구 한국동물번식학회) 2008 Reproductive & developmental biology Vol.32 No.2

Effects of alfalfa flavonoids extract on the microbial flora of dairy cow rumen

Zhan, Jinshun,Liu, Mingmei,Wu, Caixia,Su, Xiaoshuang,Zhan, Kang,Zhao, Guo qi Asian Australasian Association of Animal Productio 2017 Animal Bioscience Vol.30 No.9

Objective: The effect of flavonoids from alfalfa on the microbial flora was determined using molecular techniques of 16S ribosome deoxyribonucleic acid (rDNA) analysis. Methods: Four primiparous Holstein heifers fitted with ruminal cannulas were used in a $4{\times}4$ Latin square design and fed a total mixed ration to which alfalfa flavonoids extract (AFE) was added at the rates of 0 (A, control), 20 (B), 60 (C), or 100 (D) mg per kg of heifer BW. Results: The number of operational taxonomic units in heifers given higher levels of flavonoid extract (C and D) was higher than for the two other treatments. The Shannon, Ace, and Chao indices for treatment C were significantly higher than for the other treatments (p<0.05). The number of phyla and genera increased linearly with increasing dietary supplementation of AFE (p<0.05). The principal co-ordinates analysis plot showed substantial differences in the microbial flora for the four treatments. The microbial flora in treatment A was similar to that in B, C, and D were similar by the weighted analysis. The richness of Tenericutes at the phylum level tended to increase with increasing AFE (p = 0.10). The proportion of Euryarchaeota at the phylum level increased linearly, whereas the proportion of Fusobacteria decreased linearly with increasing AFE supplementation (p = 0.04). The percentage of Mogibacterium, Pyramidobacter, and Asteroleplasma at the genus level decreased linearly with increasing AFE (p<0.05). The abundance of Spirochaeta, Succinivibrio, and Suttonella at the genus level tended to decrease linearly with increasing AFE (0.05<p<0.10). Conclusion: Including AFE in the diet of dairy cows may alter the microbial composition of the rumen; however its effect on nutrient digestibility remains to be determined.

Effects of alfalfa flavonoids on the production performance, immune system, and ruminal fermentation of dairy cows

Zhan, Jinshun,Liu, Mingmei,Su, Xiaoshuang,Zhan, Kang,Zhang, Chungang,Zhao, Guoqi Asian Australasian Association of Animal Productio 2017 Animal Bioscience Vol.30 No.10

Objective: The objective of this study was to examine the effects of alfalfa flavonoids on the production performance, immunity, and ruminal fermentation of dairy cows. Methods: The experiments employed four primiparous Holstein cows fitted with ruminal cannulas, and used a $4{\times}4$ Latin square design. Cattle were fed total mixed ration supplemented with 0 (control group, Con), 20, 60, or 100 mg of alfalfa flavonoids extract (AFE) per kg of dairy cow body weight (BW). Results: The feed intake of the group receiving 60 mg/kg BW of AFE were significantly higher (p<0.05) than that of the group receiving 100 mg/kg BW. Milk yields and the fat, protein and lactose of milk were unaffected by AFE, while the total solids content of milk reduced (p = 0.05) linearly as AFE supplementation was increased. The somatic cell count of milk in group receiving 60 mg/kg BW of AFE was significantly lower (p<0.05) than that of the control group. Apparent total-tract digestibility of neutral detergent fiber and crude protein showed a tendency to increase (0.05<$p{\leq}0.10$) with ingestion of AFE. Methane dicarboxylic aldehyde concentration decreased (p = 0.03) linearly, whereas superoxide dismutase activity showed a tendency to increase (p = 0.10) quadratically, with increasing levels of AFE supplementation. The lymphocyte count and the proportion of lymphocytes decreased (p = 0.03) linearly, whereas the proportion of neutrophil granulocytes increased (p = 0.01) linearly with increasing levels of dietary AFE supplementation. The valeric acid/total volatile fatty acid (TVFA) ratio was increased (p = 0.01) linearly with increasing of the level of AFE supplementation, the other ruminal fermentation parameters were not affected by AFE supplementation. Relative levels of the rumen microbe Ruminococcus flavefaciens tended to decrease (p = 0.09) quadratically, whereas those of Butyrivibrio fibrisolvens showed a tendency to increase (p = 0.07) quadratically in response to AFE supplementation. Conclusion: The results of this study demonstrate that AFE supplementation can alter composition of milk, and may also have an increase tendency of nutrient digestion by regulating populations of microbes in the rumen, improve antioxidant properties by increasing antioxidant enzyme activities, and affect immunity by altering the proportions of lymphocyte and neutrophil granulocytes in dairy cows. The addition of 60 mg/kg BW of AFE to the diet of dairy cows was shown to be beneficial in this study.

한국어와 중국어의 대조를 통한 한국어 관형격 조사 `-의`의 교육방안

점소평(Zhan Su Ping),왕페이(Wang Fei) 한국중원언어학회 2016 언어학연구 Vol.0 No.41

This study started from a critical perspective that if not most or all, many current methods of teaching ‘uy’ are not systematic and efficient since many Chinese students learning Korean as a foreign language (KFL) have difficulty using ‘uy’ appropriately. Therefore, this study was intended to find out efficient methods of teaching ‘uy’ to Chinese KFL students by comparing ‘uy’ with Chinese ‘de.’ The Korean adnominal marker ‘uy’ as the Chinese postposition ‘de’ has been studied in respect to their morphologic and semantic points of view. It is generally true that there have been many studies on the meaning of those postpositions in the context and that many discussions of ‘de’ have been focussed on its function. By analysing errors identified in Chinese KFL students’ Korean composition materials, this study examined aspects of their using ‘uy’ for the ultimate goal of this study. Unfortunately, there were difficulties in setting objective standards to analyse Chinese students’ composition materials. This study conclude with the implication for the decision of when ‘uy’ should be realized or omitted because of its specific feature.

Salvage Therapy of Gemcitabine Plus Endostar Significantly Improves Progression-free Survival (PFS) with Platinum-resistant Recurrent Epithelial Ovarian Cancer

Su, An,Zhang, Jing,Pan, Zhan-He,Zhou, Qi-Ming,Lv, Xia Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Anti-angiogenic agents have played crucial roles in the treatment of ovarian cancer in recent years, but potential benefits of endostatin have been largely unexplored. The present retrospective study evaluated its efficacy and toxicity with two cohorts of patients with platinum-resistant recurrent ovarian cancer. One cohort received gemcitabine plus endostar (rh-endostatin), and the second cohort received gemcitabine regimen alone, with totals of 31 and 27 patients, respectively. The main endpoints were disease control rate (DCR), PFS, overall survival (OS) and safety. There were statistically significant differences in DCR (70.9% vs. 40.7%; P = 0.02) and PFS (6.3 months vs. 3.2 months, P = 0.001) between the two cohorts. Though the endostar cohort also improved median OS by 2.1 months, there was no statistically significant difference compared with gemcitabine alone cohort in this case (12.5 months vs. 10.4 months, P = 0.201). Treatment was well tolerated for most patients, and toxicity of endostar was negligible. Gemcitabine plus endostar significantly improved the prognosis in patients with platinum-resistant recurrent ovarian cancer, especially in those with malignant effusion. The endostar-containing regimen is recommended in this setting.

Quantum Entanglement in a Graphene Sheet

Zhan-Ning Hu,Kee-Su Park,이경수 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.54 No.2

We present the quantum entanglement and the thermal entanglement in a graphene layer. The model Hamiltonian is chosen within an effective-mass approximation, including the interaction of intervalley and intravalley scattering processes. We nd that the degenerate ground state is unentangled and that the thermal concurrence decreases down to zero as the temperature increases. A new maximally entangled quantum state is observed from the excited states of the system by using a proper choice of the Hamiltonian parameters. We present the quantum entanglement and the thermal entanglement in a graphene layer. The model Hamiltonian is chosen within an effective-mass approximation, including the interaction of intervalley and intravalley scattering processes. We nd that the degenerate ground state is unentangled and that the thermal concurrence decreases down to zero as the temperature increases. A new maximally entangled quantum state is observed from the excited states of the system by using a proper choice of the Hamiltonian parameters.

Analgesic efficacy of bilateral superficial and deep cervical plexus block in patients with secondary hyperparathyroidism due to chronic renal failure

Yinglan Su,Zhongjun Zhang,Qiuli Zhang,Yaoxian Zhang,Zhanli Liu 대한외과학회 2015 Annals of Surgical Treatment and Research(ASRT) Vol.89 No.6

Purpose: Secondary hyperparathyroidism (SHPT) develops in patients with chronic renal failure. This study aimed to compare analgesic efficacy in SHPT patients who undergo subtotal parathyroidectomy after superficial versus deep cervical plexus block. Methods: Sixty chronic renal failure patients with SPHT scheduled for subtotal parathyroidectomy were randomized to receive general anesthesia (group GA), general anesthesia plus bilateral superficial and deep cervical plexus block (group BD), or general anesthesia plus bilateral superficial cervical plexus block (group BS) (n = 20). Bilateral superficial cervical plexus block or combined superficial and deep cervical plexus block with 0.5% ropivacaine was administered. Postoperative pain was assessed using visual analogue scale (VAS). Results: VAS score at 1 hour, 4 hours, and 8 hours after operation was 3.71 ± 0.60, 2.72 ± 0.54, 2.17 ± 0.75 in BS group; 4.00 ± 0.28, 2.89 ± 0.21, and 2.46 ± 1.01 in BD group, significantly lower than in GA group (6.50 ± 0.50, 5.02 ± 0.54, and 4.86 ± 0.51, respectively). The dosage of tramadol was 109.0 ± 35.2 mg in BS group and 93.0 ± 24.52 mg in BD group, significantly lower than in GA group (300.0 ± 27.13 mg). The incidence of complications in GA group (90%) was significantly higher than in BS group (30%) and BD group (15%). Serum glucose and norepinephrine levels were significantly higher at 1 hour, 4 hours, and 8 hours after operation, but returned to baseline levels at 24 hours after operation. Conclusion: Superficial cervical plexus block or combined superficial and deep cervical plexus block effectively reduces postoperative pain, stress response, and complications in SHPT patients who undergo subtotal parathyroidectomy.

The fabrication of tungsten oxide layers on pure Al substrate by plasma electrolytic oxidation in sodium tungstate based electrolytes

Tingyan Zhan,Wenbin Tu,Yulin Cheng,Junxiang Han,Bin Su,Yingliang Cheng 한국표면공학회 2017 한국표면공학회 학술발표회 초록집 Vol.2017 No.11

A Study of Dynamic Forecast on Port Container Handling Capacity

馮湛靑(Zhan-Qing Feng),이수호(Su-Ho Lee) 한국항해항만학회 2002 한국항해항만학회지 Vol.26 No.2

컨테이너 처리량(CHC)은 항만의 능력을 나타내는 중요한 지표다. 그러나 중국항만의 컨테이너 처리능력에 대한 연구는 부족하며, 연구결과 또한 예측치와 실제치와의 차이가 크다. 이는 컨테이너처리량이 다양한 경제적인 측면을 내포하고 있고 예측모델의 선택이 매우 어렵다는데 기인한다. 대체로 지금까지 사용되어왔던 회귀분석, 신경망분석 등은 과거행태모델을 벗어나지 못하고 있어 경제체제나 항만물동량의 동태적변화에 대한 고려가 결여되어 있다. 따라서 본 논문에서는 동태적 보정인과모델을 사용한 동태적 예측법을 사용해 보았고 그 결과 보다 신뢰성이 높고 현실성이 있는 연구결과를 도출할 수 있었다. In view of the great disparity between the previous forecasts of Shanghai port container handling capacity and its real results, we choose a dynamic forecast method by the causality model with dynamic compensation to predict Shanghai port container handling capacity. And we forecast Shanghai port container handling capacity by using this method. We have made a satisfactory achievement, which provides a more reliable and practical way to forecast container handling capacity.