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황경수 淸州大學校 學術硏究所 2023 淸大學術論集 Vol.40 No.-
The purpose of the study was to discuss korean, linguistics, geography, and history by dividing it into two villages in Jincheon-eup and six villages out of 304 natural villages, and to think that place names serve as the starting point for finding language, history, and roots of jincheon-gun. The name of jincheon-gun has been changed to manno-gun→geummulno-gun→heukyang-gun→jinju→sangsan→jincheon. The name of the current jincheon began in 1413(the 13th year of King Taejong's reign) and has been 610 years to date. Place names are products of language and culture. Over the years, there must be validity and rationality in the naming rules and principles of change in korean. In the name of the natural village in jincheon-gun, it was confirmed that it was important to change and use chinese characters, but that our language and culture should be clearly recognized and utilized. I will make some suggestions to inherit and develop the natural village name of jincheon-gun. First, efforts should be made to revive jincheon's language through place names. Second, the origin of the name of the natural village lays the foundation for finding history and culture. Third, experts, members of the jincheon local history association, and jincheon cultural center should use it for education to students and local residents. Fourth, it should be applied to regional development using place names for the first time in the country. Fifth, various contents should be made with the name of a natural village. Sixth, jincheon-gun, which is good to live in, should inspire affection, pride, and pride by naming a natural village.
Early-onset epileptic encephalopathies and the diagnostic approach to underlying causes
Hwang, Su-Kyeong,Kwon, Soonhak The Korean Pediatric Society 2015 Clinical and Experimental Pediatrics (CEP) Vol.58 No.11
Early-onset epileptic encephalopathies are one of the most severe early onset epilepsies that can lead to progressive psychomotor impairment. These syndromes result from identifiable primary causes, such as structural, neurodegenerative, metabolic, or genetic defects, and an increasing number of novel genetic causes continue to be uncovered. A typical diagnostic approach includes documentation of anamnesis, determination of seizure semiology, electroencephalography, and neuroimaging. If primary biochemical investigations exclude precipitating conditions, a trial with the administration of a vitaminic compound (pyridoxine, pyridoxal-5-phosphate, or folinic acid) can then be initiated regardless of presumptive seizure causes. Patients with unclear etiologies should be considered for a further workup, which should include an evaluation for inherited metabolic defects and genetic analyses. Targeted next-generation sequencing panels showed a high diagnostic yield in patients with epileptic encephalopathy. Mutations associated with the emergence of epileptic encephalopathies can be identified in a targeted fashion by sequencing the most likely candidate genes. Next-generation sequencing technologies offer hope to a large number of patients with cryptogenic encephalopathies and will eventually lead to new therapeutic strategies and more favorable long-term outcomes.
이재선,황우준,이시형,금경수,Lee, Jae-Sun,Hwang, Woo-June,Lee, Si-Hyung,Keum, Kyeong-Su 대한한의정보학회 2008 大韓韓醫情報學會誌 Vol.14 No.1
The elementary idea of 'function-words' in Classical Chinese originates from Han dynasty. But because of the pictographic nature the methodology for 'content words' had been applied to the study on 'function words', ane the conditions had not changed until modern times. In grammar functions of the function-word syntactical, morphological in unit sentence were studied in this using the method of quantitative analysis for all the function-words appeared in ${\ll}$Hwang je nae gyung-Somun${\gg}$. In the previous studies about function word, many data were collected and analyzed diachronically. But those studies failed to examine function-words closed in connection with synchronic study. Besides, in the explain about relevant function-words also, the case which was made centering around exegetic explain was most. And in the case to explain the function-words have in unit sentence also, the explain only about some function-words is made, but the analysis about concrete function to have in syntactical system is being handled negligently. This study stands not only on the background df the traditional studies but also on the basis of the western grammar and linguistics, especially the descriptive grammar and linguistics, especially the descriptive grammar. ${\ll}$Hwang je nae gyung-Somun${\gg}$ is collect and recorded the mythology and special contents related to Daoism in the side of contents as what was written on the basis of the historical consciousness of individual in contents regardless of compilation system. The purpose of this study is to clarify how the role and function of fuction-words are being made in the composition of unit sentence which appeard in ${\ll}$Hwang je nae gyung-Somun${\gg}$ through synchronic grammar system.
Genetic Basis of Early-onset Developmental and Epileptic Encephalopathies
Hwang, Su-Kyeong Interdisciplinary Society of GeneticGenomic Medici 2021 Journal of interdisciplinary genomics Vol.3 No.1
Developmental and epileptic encephalopathies are the most devastating early-onset epilepsies, characterized by early-onset seizures that are often intractable, electroencephalographic abnormalities, developmental delay or regression, and various comorbidities. A large number of underlying genetic variants of developmental and epileptic encephalopathies have been identified over the past few decades. However, the most thorough sequencing studies leave 60-65% of patients without a molecular diagnosis. This review explores the genetic basis of developmental and epileptic encephalopathies that start within the first year of life, including Ohtahara syndrome, early myoclonic encephalopathy, epilepsy of infancy with migrating focal seizures, infantile spasms, and Dravet syndrome. The purpose of this review is to give an overview and encourage the clinicians to start considering genetic testing as an important investigation along with electroencephalogram for better understanding and management of developmental and epileptic encephalopathies.
Clinical Spectrum of Posterior Reversible Encephalopathy Syndrome in Children
Su-Kyeong Hwang,Yun-Jeong Lee,So Mi Lee,Soonhak Kwon 대한소아신경학회 2020 대한소아신경학회지 Vol.28 No.2
Posterior reversible encephalopathy syndrome (PRES) is a complex neurological condition characterized by the acute onset of neurological symptoms, such as seizures and potentially reversible vasogenic edema with preferential involvement of the parieto-occipital region in brain magnetic resonance imaging. Although PRES can present with a wide spectrum of clinical manifestations, the most common are seizures, visual disturbances, headaches, and altered mental states. PRES has been recognized in a wide variety of clinical settings including hypertension, immunosuppressants following organ transplantation, chemotherapy, renal diseases, sepsis, and autoimmune disorders. It has been increasingly reported even in children, but many aspects of this syndrome are incompletely understood and validated diagnostic criteria is still lacking. In this review, we will cover putative pathophysiological mechanisms, etiologic categories, clinico-radiological manifestations, and outcomes from previous studies.
Hwang, Su-Kyeong,Park, Ki-Su,Park, Seong-Hyun,Hwang, Sung Kyoo The Korean Neurosurgical Society 2016 Journal of Korean neurosurgical society Vol.59 No.3
Most craniosynostoses are sporadic, but may have an underlying genetic basis. Secondary and syndromic craniosynostosis accompanies various systemic diseases or associated anomalies. Early detection of an associated disease may facilitate the interdisciplinary management of patients and improve outcomes. For that reason, systematic evaluation of craniosynostosis is mandatory. The authors reviewed systematic evaluation of craniosynostosis with an emphasis on genetic analysis.