타액선 세포에서 내인성 산화질소에 의한 칼슘유입 조절기전

최경자,정성수 전남대학교 치과대학 1996 전남치대논문집 Vol.8 No.1

Nitric oxide (NO) has been known to function as a cellular signaling messenger in various tissues and organs. The present study was aimed to investigate whether the regulatory mechanisms of calcium influx are mediated by the endogenous NO in submaxillary acinar cells. Effects of agents which stimulate or inhibit the NO-cGMP pathway on the calcium influx and potassium efflux were examined in submaxillary cells of the rat in vitro. 1) In the submandibular slices, carbachol (10^-5 mol/L) increased the NO_2 contents, which was prevented by pretreatment with L-NAME. 2) In the submandibular slices, K^+ efflux in response to carbachol (10^-5 mol/L) was significantly inhibited by pretreatment with L-NAME (10^-4 mol/L) which was attenuated by L-arginine (10^-5 mol/L). 3) L-NAME (10^-4 mol/L) did not affect the transient K^+ efflux in response to carbachol (10^-5 mol/L), but decreased the sustained K^+ efflux. 4) In the isolated submandibular acini, calcium influx by carbachol (10^-5 mol/L) was reduced by L-NAME or L-NMA. 5) In the isolated submandibular acini, calcium influx induced by sodium nitroprusside (10^-6 mol/L) was attenuated by pretreatment with hemoglobin (10^-4 mol/L) or methylene blue (10^-4 mol/L). 6) Calcium influx by 8-Br-cGMP (10^-4 mol/L) was inhibited by H8, (10^-4 mol/L). 7) Calcium influx by 8-Br-cGMP was not affected by nifedipine or verapamil (10^-5 mol/L) but was slightly decreased by reduction of extracellular sodium concentration. These results suggest that endogenous NO stimulates Ca^2+ influx through activating a cGMP-dependent protein kinase-activated nonselective cation channel in submandibular acinar cells.

담배식물의 생장에 따른 Holocellulose와 Lignin 함량의 변화

이학수,이경훈,오지훈 충북대학교 연초연구소 2009 煙草硏究 Vol.22 No.-

본 연구는 담배식물의 바이오에타놀 생산원료서의 가능성을 타진하기 위하여 온실에서 pot재배를 통하여 이식 후 25일부터 80일까지 5일 간격으로 잎과 줄기의 holocellulose와 lignin함량 변화를 조사해 보았다. 생육이 진행됨에 따라 건물 g당 holocellulose와 lignin의 함량도 증가하여 성숙 및노화기로 갈수록 높았다. 건물 g당 holocellulose함량은 잎보다 줄기가 높았고, 줄기의 lignin함량은 최대생장기에 급격히 증가했다. 담배 1주당 총 함량은 이식 후 70일에 최대였는데, holocellulose함량은 건물중의 60%이었고 lignin을 합할 경우에는 67%가 되었다. Changes in holocellulose and lignin contents of tobacco p1ants(var. NC 82) were determined from 25 days after transplanting in a pot to senescence stage at 5 days interval in green house. The amount of holocellulose and lignin per g of dry matters were increased from growing to senescence stage. The hollocellulose content of dry stalk was higher than of leaf, and lignin content of stalk was increased rapidly during the maximal growing stage of tobacco plant. The total amounts of holocellulose and lignin per a tobacco plant were reached maximum at the around 70 days after transplanting. At that time, the ratio of holocellulose only and holocellulose with lignin to dry matter was about 60% and 67%, respectively.

현대국어 의존명사의 선․후행환경자질과의 통합관계

황경수 청주대학교 인문과학연구소 2008 人文科學論集 Vol.37 No.-

This thesis is the purpose of dicussing that it is the meaning characteristic about the bound noun antecedent and escorting environment feature in the korean language. The result of this study can be conclued as follows. A bound noun, unlike the free, cannot be used alone, and should be preceded by an ad-nominal form-ad-nominal form of a predicate, substantive, or demonstrative ad-nominal form, etc. In this study, I investigate which lexical items belong to a free noun, clitic and the ending of a word through the syntactic and semantic study of the bound noun in modern korean. So, it is desir to make a study on the bound noun in korean and thus make a full escription on the diachrinic development of the bound noun in the korean language. For the distictions, the bound noun selected can be listed as follows. ‘kot, kyeoreul, noreut, taero, tai, deung, deungdeung, teut, stayeo, starum, manchi, pa, param, pun, syeom, su, yang, i, cheok, chul, ahung, chae, aheok, tat, teo, pyeon’

훈민정음 용자례의 분석

황경수 청주대학교 학술연구소 2015 淸大學術論集 Vol.2015 No.S-9

This study is to analyze the yongjarye of Hunminjeongeumhaerye First, the original is analyzed yongjarye. Second, the example of 23 characters each consonant is byeon gseo and ‘ㆆ’ was to illustrate. Yongjarye two pairs of 34 characters each character of ‘ㅸ’ was added. 11 characters of Yeui medial consonant is addressed. And consonant clusters (2characters) and consonant clusters (3 characters) of the four who did not disclose of the 14 who were exemplary. The neutral consonant yongjarye consists of 44 characters, 4 characters each pair. Yeui final consonant in the first spellings as the granulomatous was explained. And two pairs of 16 characters yongjarye dealt with granulomatous, was limited to eight characters. Third, Yeui first consonant a velar sound 2, a lingual sound 2, a labial soun d 1, a dental sound 2, a guttural sound 1, half dental sound 1 was illustrated. However velar sound (快, 虬) 2, a lingual sound 斗, 那) 2, a labial sound(漂, 弥, 步) 3, a dental sound(慈) 1, a guttural sound(揖, 虚) 2, half dental sound (闾) 1, 11characters are not illustrated. Third, yongjarye consonant, neutral, granulomatous hyperonym of the ‘creature’ 43, ‘plants’ 19, ‘range’ 16, ‘equipment’ 12, ‘target’ 11, ‘shape’ 4, ‘phenomenon’ 3, ‘space’, 3, ‘s tatus’, such as 2 respectively. In addition, the entire word list yongjarye 54 monosyllabic, two -syllable, and 40 of them have to configure the list.

즉흥사고를 이용한 글쓰기 전략 개발 연구

김재수,임성규,김재봉,정경미 광주교육대학교 초등교육연구소 2001 初等敎育硏究 Vol.15 No.2

The purpose of this study was to develop an writing strategy with brainstorming. Concrete instructional contents for the dvelopment of writing strategy with brainstorming and the continuous application of the strategy to the whole writing's processes were developed here. And its method of application to elementary school and university were also described. The modern writing theory which reflects the importance of thinking had emphasis on the diversification of thinking ability. From this point of view, brainstorming which is adopted to a way of enhancing thinking ability was applied to students' writings. Brainstorming aims to pull out the unique idea from the consciousness of students and this study tried to develop continuous model of writing strategy through brainstorming. The advantage of continuous model could be in teaching the students interactively for whole writing processes. This study showed that brainstorming could be applied to the whole writing process, idea production - idea construction - paragraph writing, and described the results of its application at the order of method - application - consideration of instruction.

양극성 장애에서 표피성장인자의 유전적 다형성에 대한 연합연구

김수경,이규영,주은정,강웅구,안용민,김용식 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : Epidermal growth factor (EGF) is a neurotrophic factor which regulates the intracellular signaling molecules. These molecules are also affected by mood stabilizers such as lithium and valproate. In addition, epidermal growth factor enhances neuronal survival, maturation and differentiation especially in midbrain dopaminergic neurons of which dysfimction may play a role in pathophysiology of bipolar disorders. Bipolar disorder has some genetic commonalities with schizophrenia, and several association studies of EGF have been done with schizophrenia. In this study, we tried to investigate the geneticassociation between EGF A61G polymorphism and bipolar disorder. Methods : Total of 189 patients and 347 nonnal control were included. All patients satisfied the diagnostic criteria of DSM-IV for bipolar disorder type I (BPDI, N= 146) and bipolar disorder type II (BPDII, N=43). Genomic DNA was extracted from the peripheral blood, and genotyping was performed by TaqMan™ method. Genotype and allele frequency of EGF A61G polymorphism between the patients and the control were compared by contingency chi-square test or the Fisher's exact test. Results : No association was found between EGF A61G polymorphism and susceptibility of BPDI, BPDII and bipolar disorder (all patients). Female patients with BPDII showed overexpression of AG genotype compared to that ofcontrol group (p=0.03). However, this association was not significant after correction of multiple testing. Conclusion : In conclusion, EGF A61G polymorphism has no association with susceptibility of bipolar disorder. However, the disease modifying role of EGF gene polymorphism for bipolar disorder remains to be elucidated in respect to factors such as gender difference or diagnostic subtype.

간호사의 셀프리더십과 간호업무성과간의 관계

서문경애,장성옥,조경희,김인아,이수정 대한간호학회 간호행정학회 2006 간호행정학회지 Vol.12 No.1

Purpose: This study was undertaken in order to suggest self-leadership as a way to promote organization efficiency of nursing organization. So the relation between self-leadership and outcome of nursing practice inorganization was studied. Method: The subjects of study were nurses as a population who were working for the 2 of university hospitals which have over 500 beds in Kyong Ki Province as well as who have been working for over 6 months. The data was collected by questionnaires from 215 nurses and analyzed using descriptive statistics, perason correlation coefficient, t-test and ANOVA on SAS Program. Results: Self-leadership of nurse got 3.51 grade out of 5 as a mean point. Each of the segments got 3.74 in self-compensation, 3.57 in self-expectation, 3.53 in goal-setting, 3.45 in rehearsal, 3.37 in self-criticism and 3.30 in constructive thinking in order. Independent performance of nursing practice at each items of outcome of nursing practice showed the highest correlations with the self-expectation among self-leadership segments. Constructive thinking, self-compensation, rehearsal, goal-setting were related like this in order, but self-criticism was related just a little. Dependent nursing practice has the highest correlation with the self-expectation, goal-setting, rehearsal, constructive thinking, self-compensation were similar as aboves in order, but self-criticism didn't show any similar correlations. Relationship practice has the highest correlation with the self-expectation, and goal-setting, constructive thinking, self-compensation, rehearsal were similar, while self-criticism did not show any correlations. Conclusion: In conclusion the result was obtained that self-leadership is much correlated with outcome of nursing practice. Therefore, as a way to promote efficiency of nursing organization, the constant study about self-leadership with the various aspects is needed focusing on self-management and inner motivation as a new leadership paradigm.

공무에서 사용하는 법령문 띄어쓰기를 위한 소고

황경수 청주대학교 인문과학연구소 2007 人文科學論集 Vol.36 No.-

The purpose of this thesis arranges a way of writing rightly in the line of duty on the basis of things that analyzed the parts making a popular fallacy systematically, the provisions of spacing words in Han-geul orthography, the consideration and the right plan of spacing words in decree, etc. in the way of spacing words. When we write a composition, It is spacing words that one of the hardest things and also everybody will have a experience that they can't make up mind whether to space out words or not while writing a composition. That's because it's not only depending on their myopic outlook but also not understanding the basic principle of spacing words. Today, spacing words in different systems are interfered with having broaden native speaker‘s horizons in newspaper, magazine and the mass media, etc. and it have a bad influence upon them. Spacing words is also our unique writing way and it is mostly of no use to use a korean dictionary for searching it, so we feel tight. If we do not polish up the personal sentence expression, there'll be difficulty to transmit the meaning. An official document will be same. If the sentence of the document is not made up well, the effective value of the document decreases. So those who draw up the document need to make the sentence written by themselves as an exemplary sentence. The public official is both a servant of the people and a leader, so they have to show a fine example of linguistic function. Once the paper in an administrative organ is shown a good example of proper and correct sentence, it'll have an influence on the general public's drawing up the sentence. Then the effective value of the document will increase much more. Key Words: Eeomungyubeom(어문규범), Ttui-eosseugi(띄어쓰기), Bound Noun(의존명사), Postposition(조사), Adverb(부사)

순·구개열 환자의 두부규격방사선사진상을 이용한 친자간의 유사성에 관한 연구

이언경,나승목,고광준,조수범 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.2

The purpose of this study was to determine whether any similarity existed in craniofacial morphology between parents and offspring in cleft lip with or without cleft palate. Thirty three measurements of the various regions of cranium and face were obtained from lateral cephalometric radiograms in 28 families comprising 28 fathers, 28 mothers and 28 cleft patients. The measurements of cleft patients were compared with those of their fathers, mothers and midparents. The obtained results were as follows: 1. There were similar measurements between the cleft patients and their father; ramal height(Ar-Go), mandibular angle(∠MP-RP). 2. There were similar measurements between the cleft patients and their mothers; cranial base angle(∠NSBa), relation of maxilla to the cranial base(∠SNA), relation of maxilla to the cranial base(soft tissue:∠BaN"Sn), angle of inferior border of mandible(∠SNL-MP) and convexity of nose apex(soft tissue:N"PrnPog"). 3. There were similar measurements between the cleft patients and their mdparents; ramal height (Ar-Go), cranical base angle(∠NSBa), relation of maxilla to the cranial base(soft tissue:∠BaN"Sn), Y axis angle(∠NSGn) and mandibular angle(∠MP-RP). 4. There was no similar measurements between the cleft patients and their fathers and mothers simultaneously.

행정심판에서 재결의 효력

여경수 忠北大學校 法科大學 法學硏究所 2013 法學硏究 Vol.24 No.1

The central administrative Appeals commission which has been correcting national organizations' wrong administrative doings and protecting citizens' rights. This study focuses on Scope of Ruling and Binding Force, etc. of Ruling. If an appeal is unlawful, a commission shall dismiss it. If a commission finds that an appeal is groundless, it shall reject the appeal. If a commission finds that an appeal for revocation is well-grounded, it shall revoke or alter the disposition or order the administrative agency which made such disposition to revoke or alter it. If a commission finds that an appeal for affirmation of nullity, etc. is well-grounded, it shall affirm as to whether a disposition is effective, or whether a disposition has been made. If a commission finds that an appeal for performance of obligation is well-grounded, it shall promptly make a disposition in conformity with the request, or order to do so to an appellee. Circumstantial Rulings ; Even if a commission deems that an appeal is well-grounded, if accepting it is believed to be detrimental to the public welfare, it may reject the appeal. In such cases, the commission shall specify it in the main sentence of the ruling that the disposition or omission is unlawful or unreasonable. A ruling shall be made within 60 days from the date on which an appellee or a commission has received a written appeal. Provided, That if unavoidable circumstances exist to the contrary, a chairperson may extend the period thereof by 30 days ex officio. A commission shall not make any ruling on matters, other than a disposition or omission which is the subject matter of an appeal. A commission shall not make any ruling more unfavorable for the appellant than a disposition which is the object of an appeal. A ruling recognized by an appeal shall restrict an appellee and other relevant administrative agencies. 행정심판위원회는 행정의 잘못을 바로 잡아서 국민의 권리를 보장하고 있다. 본 논문은 재결의 효력과 범위를 중점으로 다룬다. 재결의 공정성과 실효성을 확보하여 행정심판의 목적을 실현해야한다. 재결은 각하, 기각, 인용으로 구분된다. 위원회는 심판청구가 적법하지 아니하면 그 심판청구를 각하한다. 위원회는 심판청구가 이유가 없다고 인정하면 그 심판청구를 기각한다. 위원회는 취소심판의 청구가 이유가 있다고 인정하면 처분을 취소 또는 다른 처분으로 변경하거나 처분을 다른 처분으로 변경할 것을 피청구인에게 명한다. 행정심판위원회는 심판청구가 이유가 있다고 인정하는 경우에도 이를 인용하는 것이 공공복리에 크게 위배된다고 인정하면 그 심판청구를 기각하는 재결을 할 수 있다. 이를 사정재결이라고 한다. 이 경우에는 위원회는 재결의 주문에서 그 처분 또는 부작위가 위법하거나 부당하다는 것을 구체적으로 밝혀야 한다. 재결의 기간은 피청구인 또는 위원회가 심판청구서를 받은 날부터 60일 이내에 하여야 한다. 다만, 부득이한 사정이 있는 경우에는 위원장이 직권으로 30일을 연장할 수 있다. 재결의 범위는 위원회는 심판청구의 대상이 되는 처분 또는 부작위 외의 사항에 대하여는 재결하지 못한다. 위원회는 심판청구의 대상이 되는 처분보다 청구인에게 불리한 재결을 하지 못한다. 그리고 재결의 기속력으로 심판청구를 인용하는 재결은 피청구인과 그 밖의 관계 행정청을 기속한다.