근 근막 통증 증후군 환자의 전기 자극 초음파 치료의 유용성

한승문,이상철 大韓痛症學會 1997 The Korean Journal of Pain Vol.10 No.-

척추 후관절 증후군 환자에서 히알우론산을 이용한 치료의 유용성

한승문,이상철 大韓痛症學會 1997 The Korean Journal of Pain Vol.10 No.-

유치열에서 Chlorhexidine Varnish와 Polyurethane Sealant의 Streptococcus mutans억제 효과에 대한 연구

이성혁,장기택,김종철 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.1

Numerous chemical agents have been developed to reduce the activity of cariogenic bacteria. Of these, chlorhexidine is acknowledged as the most effective. Gel and mouthrinse have been the traditional method of its application in the mouth. It has been reported that chlorhexidine varnish has prolonged inhibitory effect on the number of streptococcus mutans in saliva and plaque. Recently, chlorhexidine varnish and polyurethane sealant have been developed to promote prolonged anticariogenic effect of chlorhexidine. Products containing 10% chlorhexidine varnish and polyurethane sealant have been developed to prevent caries by reducing the number of streptococcus mutans in the oral cavity. The purpose of this study is to investigate the inhibitory effect of chlorhixidine varnish and polyurethane sealant on streptococcus mutans in the primary dentition. Children with primary dentition containing no active carious lesion were divided into two groups. To the experimental group(n=11), chlorhexidine varnish and polyurethane sealant ( Chlorzoin , Knowell Therapeutic Technologies, Inc. Canada.) was applied once a week for four weeks according to the manufacturer's instruction. Only oral prophylaxis was performed on the control group(n=7). Cariesactivity was measured after using Chlorzoin SM(Knowell Therapeutic Technologies, Inc. Canada.) to incubate streptococcus mutans before and 5, 12, 24 weeks after initial varnish application. The following results were observed.: 1. There was statistically significant decrease in the number of streptococcus mutans in the experimental group for 5 weeks(P<0.01), 12 weeks(P<0.05) after the initial application. but, by 24 weeks significant difference had disappeared. 2. As the inhibitory effect of chlorhexidine varnish and polyurethane sealant application is not everlastion, reapplication at 12-24 weeks should be needed.

素部分加群의 性質에 관한 硏究 Ⅱ

李承哲 삼척대학교 1997 論文集 Vol.30 No.3

單位元을 갖는 可換環 R위에서 加群 M의 眞部分加群 N에 대하여 're∈N(r∈R, e∈M)⇒e∈N 이거나 r∈p = (N : M)' 을 滿足하면 N을 素部分加群이라고 한다. R-加群 M으로부터 R의 이데알 들의 集合으로의 函數 c를 M의 任意의 元素 x에 대하여 c(x)=∩{A|A는 R의 이데알 이고 x∈AM} 로 定義할 때 c를 內容函數라 한다. 특히 M의 任意의 元素 x에 대하여 x∈c(x)M을 만족하면 M을 內容加群이라 한다. 本 論文에서는 素部分加群과 內容加群의 性質들을 調査硏究하고 素部分加群과 內容加群의 關係를 硏究하였다. 本 論文의 主 定理는 다음과 같다. 정리 3.4 M이 忠實한 곱셉 R-加群이면 다음 두 命題는 同値이다. (1) 任意의 元素 r∈R와 x∈M에 대하여 r c(x)⊂√c(rx)이다. (2) 각 δ∈Spec(R)에 대하여 δM=M이거나 또는 δM은 δ-素部分加群이다. 정리 3.6 {Mλ|λ∈A}를 R-加群들의 集合族이라 하고 M=?Mλ을 忠實한 加群이라 하자. 또 다음 두 條件이 成立한다고 하자. (가) 각 λ∈A에 대하여 Mλ가 忠實한 곱셈 R-加群이고, (나) 각 λ∈A에 대하여 AλMλ=Mλ와 AλMλ*={0}을 滿足하는 R의 이데알 Aλ가 存在한다. 이 때, 다음 두 命題는 同値이다. (1) 任意의 元素 r∈R와 x∈M에 대하여 r c(x)⊂√c(rx)이다. (2) 각 δ∈Spec(R)에 대하여 δM=M이거나 또는 δM은 δ-素部分加群이다.

Genesis 영상처리 보드를 이용한 의용 영상 실시간 에지 검출

심성균,정원영,이영철 경남대학교 공업기술연구소 2000 硏究論文集 Vol.18 No.-

인터넷과 전자산업기술의 발달로 영상의 획득과 처리를 동시에 수행하는 실시간 처리 기술이 용이하게 되었다. 본 논문에서는 심장혈관의 위치, 모양, 크기 등의 정보를 우리에게 알려주는 의용 영상의 에지검출에 Genesis 보드와 이를 제어하는 MIL 패키지를 사용하여 실시간 개념을 적용한 실험을 구현해 보았으며, 획득한 영상에 적용한 마스크의 크기에 따른 영상처리 속도와 실시간 개념에 맞는 최대 제한 속도를 조사해 보았다. The development of electronics and internet technologies is enable to perform of real-time image acquisition, processing, and transmission almost simultaneously. In the paper, real-time edge detection of the medical coronary angiograms image was accomplished by making use of the Genesis H/W board and the MIL(Matrox Image Library) S/W package. The comparison of the processing time for the various mask to detect the edges of the given image shows the determination about the limited mask size under the real-time processing environment.

용접공에서 혈중 중금속 농도와 혈장중 Malondialdehyde, α-tocopherol 및 적혈구내 Superoxide Dismutase 활성도에 관한 연구

이원진,장성훈,황천현,천병철,김해준 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2

We investigated the association between the oxidative stress and the concentration of heavy metals in blood among welders. The study subjects were male manual CO₂welders(N=127) exposed to several heavy metals. The age distribution was from 20 to 63(GM=33.7) and the geometric mean(GM) of work duration was 4.2 years. We analyze the level of blood lead, cadmium, manganese and chromium which was related with the oxidative stress in the animal studies. Blood selenuim, plasma malondialdehyde(MDA), plasma α-tocopherol and erythrocyte superoxide dismutase(SOD) were analyzed as biological markers of the oxidative stress. The results of univariate analysis showed that the plasma MDA was significantly correlated with α-tocopherol(r=0.327) and blood selenium(r=0.313) concentration. But we could not find out any relationship between the erythrocyte SOD activities and those metal concentrations. Neither smoking nor alcohol consumption was related to the level of heavy metals and the oxidative stress biomarkers. As the results of multiple regression analysis with stepwise selection method, 1) the change of MDA level were dependent with the level of α-tocopherol and blood selenium concentration(R²=19.7), 2) the plasma α-tocopherol level was dependant with MDA and blood chromium concentration(R²=15.6), 3) in case of erythrocyte SOD activity, only the duration of work was significantly selected.

Benz(a)anthracene이 마우스태자 간조직 세포의 소핵출현에 미치는 경태반효과

成耆天,張聖薰,車喆煥 고려대학교 의과대학 1989 고려대 의대 잡지 Vol.26 No.1

In order to adduce the cytogenic effect of Benz(a)anthracene(B(a)A) in pregnant mice through placental barrier to fetus, 125㎎/㎏, 250㎎/㎏, 500㎎/㎏, of B(a)A were administrated to groups of mice 16th pregnancy day About 20 hrs later, freauency of micronuclei in polychromatophilic normoblasts of liver tissues extracted from fetus was measured At the same time, 200 ㎎/㎏ and 400 ㎎/㎏ of Benzo(a) pyrene(B(a)P) were administered with same procedure to compare the frequencies between in cases of B(a)A and B(a)P administration. Especially incase of B(a)A administration, frequencies of their appearances in bone marrows of mother mice and livers of fetuses were compared. On the other hand, pathological changes of fetus liver caused by B(a)A and B(a)P in mothers were observed through microscopic examination in order to reconfirm and compare their transplacental effects. As the results, cytogenic toxicity for feture caused of B(a)A was confirmed. It means that some amount of B(a)A which was administered to pregnant mice could be transmitted to fetus through placental barriers Mutagenicity caused of B(a)A was higher in fetus than mother mouse. The cytogenic toxicity caused of B(a)A both for mother mouse and fetus was lower than that of B(a)p.

소아치과 영역에서 러버댐의 다양한 임상적 적용에 대한 증례보고

김종범,김종철,이성혁,장기택 大韓小兒齒科學會 1997 大韓小兒齒科學會誌 Vol.24 No.3

Usage of the rubber dam has been advocated by countless number of dentists. The advantages of the rubber dam such as the following are well-known 1. Moisture control. 2. Improved field of vision. 3. Ease of approach. 4. Soft tissue retraction and Injury prevention. 5. Prevention of aspiration of materials or instruments. 6. Shortened chair time. 7. Induction of nasal breathing during administration of N₂O-O₂sedation. Recent reports indicate the rubber dam can protect the dental staffs from the infection when treating HBV or HIV positive patients. Also, impreved moisture control and freeing of both handes allowed by the rubber dam makes it very useful when bonding orthodontic brackets. This case study presents the various clinial application of the rubber dam on patients visiting SNUDH dept. of pediatric dentistry to emphasize the importance of its use in pediatric dentistry.

大氣汚染物質의 變異原性에 關한 硏究 : 마우스 母體 및 胎仔의 小核試驗을 中心으로

韓東宣,車喆煥,張聖薰,裵思相 고려대학교 의과대학 1989 고려대 의대 잡지 Vol.26 No.3

This Study aimed at identifying the cytogenic effect of air pollutants in pregnant mouse and her fetus. Samples of air pollutants were collected by the high volume air sampler in several sites of Seoul from May through December in 1988. Total suspended particulates (TSP) were measured and those of benzene and methanol were extracted and dissolved in dimethyl sulfoxied (DMSO). Those were injected into peritoneal cavity by the concentration and the micronucleated polychromatic erythrocyte (MNPCE) was observed in the bone marrow of mother mice. IN addition, the liver of fetus was extracted and MNPCE was observed. Transplacental genetic toxicity due to air pollutants in both cases was measured in the end. 1. In case of the tar concentration equivalent to those residing in the volume of 100m³ of air, the MNPCEs in the mother's bone marrow were 0.57±0.15% and 0.70±.20% in Shinchon; 0.27±0.17% and 0.40±0.13 In Jungrung and in the underground shopping center ; 0.33±0.10% and 0.55±0.13% in the subway station. The MNPCEs measured in the sample of the tunnels, of which tar concentration was equivalent to that in 50m³ and 100m³ of air, were 0.86±0.24% and 1.06±0.17% in tunnel A and 0.70±0.15% and 0.96±0.23% in tunnel B; those were the highest MNPCE in the samples of mother mice. 2. The MNPCEs measured in the liver of featus were 0.60±0.25% and 0.80±0.15% in Shinchon. In Jungrung and the underground shopping center, the MNPCEs in the liver of fetus were the same as those in mothers. In the sample of the subway station, the MNPCEs in the liver of fetus, 0.73±0.20%, were higher than in mothers only in the 200? tar concentration. The MNPCEs in the 50m³ and 100m³ tar concentration were 0.87±0.10% and 1.27±0.27% in tunnel A, and 0.68±0.41% and 1.07±0.23% in tunnel B. It showed that the MNPCEs only in the 100m³ tar concentration were higher than those in mothers.

이황화탄소 폭로 근로자의 요중 N-Acetyl-β-Glucosaminidase Activity 및 Total protein에 관한 연구

趙浚吉,李恩一,車喆煥,張聖薰 고려대학교 의과대학 1992 고려대 의대 잡지 Vol.29 No.1

The results of renal function studies among 45 workers exposed to carbon disulfide as measured bv total protein in a 24-hour urine and N-Acetyl-β-Glucosaminidase (NAG) activity in both 24-hour and spot urine, were further analyzed by fundoscopic examination for evidence of retinopathy. By Measuring spot urine NAG activity in 69 healthy workers, a comparative analysis of spot urine NAG activity was made between healthy workers and those exposed to carbon disulfide and the results were as follows: 1. Of the workers exposed to carbon disulfide, 53.3% had retinopathy, 53.3% showed increased NAG activity above reference value, and 20.0% had proteinuria. These rates tended to increase as the age of the workers and their duration of exposure increased. 2. For workers exposed to carbon disulfide and having retinopathy, the mean value of NAG activity and total protein amount in 24-hour urine were significantly higher (p<0.05), as compared to those having normal retina. 3. Mean values of spot urine NAG activity in healthy workers, those exposed to carbon disulfide with normal retina, and those having retinopathy were 199.1μM of 4-MU/mgCr., 499.1μM of 4-MU/mgCr., and 902.7μM of 4-MU/mgCr., respectively, showing a statistically significant difference.