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Soonjae Kwon 한국인터넷전자상거래학회 2018 인터넷전자상거래연구 Vol.18 No.2
In the field of decision making field, cognitive map (CM) has been regarded as a unique and robust mechanism for problem-solving. Despite that a huge number of studies had been reported about the usefulness of cognitive map on complicated decision making problems, there is no explicit study on how the CM influences decision makers’ semantic and syntactic comprehension, and inferential problem-solving. To fill the research void like this, this study proposes related hypotheses, and conducts experiments in which participants are grouped into two application domain types (familiar vs unfamiliar), and two types about CM knowledge (high CM knowledge vs low CM knowledge). Experimental results showed that CM can be used in significantly enhancing decision makers’ semantic and syntactic comprehension, as well as inferential problem-solving.
Soonjae Hwang,Min Ho Lee,Sun-Yeong Gwon,Seunghyung Lee,Dongju Jung,Ki-Jong Rhee 대한의생명과학회 2013 Biomedical Science Letters Vol.19 No.2
Enterotoxigenic Bacteroides fragilis (ETBF) causes inflammatory diarrhea in humans and animals and is also implicated in colorectal cancer. ETBF-infected mice exhibit a prominent large intestinal inflammation characterized by neutrophil infiltration and induction of the Th17 response. In this study, we examined differences in the secreted cytokine profile of the cecum and proximal colon of ETBF-infected mice using an antibody array. Of the cytokines examined, we found that the cecal tissues from ETBF-infected mice secreted elevated levels of G-CSF, IL-6, IL-17 and LIX compared to non-toxigenic Bacteroides fragilis (NTBF) and Mock infected mice. The proximal colon tissues from ETBF-infected mice secreted higher levels of G-CSF, IL-6, KC, LIX, MIP-1g and MCP-1. This study demonstrates that the cecum and colon should be considered separately when assays are used to determine immune responsiveness to enteric infections.
High Sodium Diet and Autoimmune Diseases
Soonjae Hwang,Hohyun Park,Ki-Jong Rhee 대한의생명과학회 2015 Biomedical Science Letters Vol.21 No.3
High sodium diet has been touted to be a major risk factor of disease in developed countries. The disease most closely associated with a high sodium diet is cardiovascular diseases. Autoimmune diseases are another broad spectrum of diseases that is associated with developed countries. In the past few years, several key scientific findings have revealed that a high sodium diet could also impact the pathogenicity of autoimmune diseases. In this review, we will highlight key results from such investigations and put it in context of high sodium diet and autoimmunity.
Targeting the Gut Microbiome to Ameliorate Cardiovascular Diseases
Soonjae Hwang,Chan Oh Park,Ki-Jong Rhee 대한의생명과학회 2017 Biomedical Science Letters Vol.23 No.3
The bacterial cells located within the gastrointestinal tract (GIT) outnumber the host"s cells by a factor of ten. These human digestive-tract microbes are referred to as the gut microbiota. During the last ten years, our understanding of gut microbiota composition and its relation with intra- and extra-intestinal diseases including risk factors of cardiovascular diseases (CVD) such as atherosclerosis and metabolic syndrome, have greatly increased. A question which frequently arises in the research community is whether one can modulate the gut microbial environment to "control" risk factors in CVD. In this review, we summarized promising intervention methods, based on our current knowledge of intestinal microbiota in modulating CVD. Furthermore, we explore how gut microbiota can be therapeutically exploited by targeting their metabolic program to control pathologic factors of CVD.
Integrated Framework for FUN on the Internet and Mobile Services
Soonjae Kwon,Emy Elyanee Mustapha 한국인터넷전자상거래학회 2016 인터넷전자상거래연구 Vol.16 No.2
This research was designed 1) to define and validate fun as a construct; 2) to compare two different applications(Internet and mobile services). The new four dimension of fun are introduced which are sociability, contentment, achievement and enthusiasm. Dimension of fun is critical to understand IS differentiated between new and established applications. The development of the new fun construct should be extended further to include bigger and wider range of sample especially during the content validation. The comparison study done for to compare usage of mobile service and Internet showed interesting results. These results are suggesting that application types do differentiate type of fun that users experience.
Soonjae Jung,Jae Yong Choi,Jung Young Kim,Sang-Jin Han,Youngbeom Seo,Kyo Chul Lee,Young Hoon Ryu 대한방사성의약품학회 2019 Journal of radiopharmaceuticals and molecular prob Vol.5 No.1
A bone metastasis is an important factor for prognosis and treatment of breast or prostate cancer patients. [18F]Sodium fluoride ([18F]NaF) is a PET radiopharmaceutical that can detect bone metastasis. Conventional[18F]NaF production process included radioactive metal impurities because the product was prepared byadding saline after beam irradiation to [18O]H2O. In this study, we apply the method of removing radionuclidicimpurities. To meet the criteria prescribed by GMP in quality control, we designed the custom-made [18F]NaFautomatic module. The mean radiochemical yield was 82.1 ± 4.4% (n = 32) productions for 3 years) and thetotal preparation time was 4 min. The final produced [18F]NaF solution meets the USP criteria for quality control. Thus, this fully automated system is validated for clinical use.
Why Users Continue to Use SNS(Social Network Services)?
Soonjae Kwon 한국인터넷전자상거래학회 2015 인터넷전자상거래연구 Vol.15 No.2
Most people are spending more time on SNS than on video call, voice call and SMS, in korea. Why do users spend so much time on using SNS? Do we use SNS just for fun or for getting information and knowledge? Or maybe we are just addicted to it? To explore the users" action of continually using SNS, we suggest a set of propositions in this exploration and put forward three kinds of methods to prove the propositions true. In this paper, we also put forward a new viewpoint according to Aristotle"s Teleology, Praxeology and Evolutionary Psychology. We have four main steps in this paper for exploring SNS users" actions of continuance usage and finally try to prove the proposition. First, study the concept of the existing information system, Praxeology, Aristotle"s Teleology and Evolutionary Psychology; Second, analysis the behavior patterns of users who continually use SNS; Third, find the relationships between the concepts and users’ actions; Forth, propose propositions and try to prove them true through those correlative analysis.