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Spin-orbit torque engineering by orbital current in Cr-based magnetic heterostructures
Soogil Lee,Min-Gu Kang,Dongwook Go,Taekhyeon Lee,Dohyoung Kim,Geun-Hee Lee,Jun-Ho Kang,Jong-Ryul Jeong,Kyung-Jin Lee,Hyun-Woo Lee,Kab-Jin Kim,Sanghoon Kim,Byong-Guk Park 한국자기학회 2020 한국자기학회 학술연구발표회 논문개요집 Vol.30 No.1
Soogil Chae,Inkyu Yoo,Jisoo Han,Hwanhee Jang,Soohyung Lee,Hakhyun Ka 한국동물생명공학회(구 한국동물번식학회) 2017 Reproductive & Developmental Biology(Supplement) Vol.41 No.2
For successful pregnancy, the appropriate interactions between the maternal endometrium and the implanting conceptus are essential during the implantation period. In pigs, the implanting conceptus produces estrogens, interleukin 1 beta (IL1B), interferon delta (IFND) and interferon gamma (IFNG) during early pregnancy. Estrogens are produced by CYP19A1, a key enzyme for estrogen biosynthesis, and play a role in maternal recognition of pregnancy in pigs. IL1B is known to be involved in production and transport of prostaglandins in the endometrium. The role of IFND and IFNG during the implantation period is not fully understood. Also, localization of CYP19A1, IL1B, IFND and IFNG in the implanting conceptus is not fully understood. Thus, this study determined the localization of these molecules in conceptus during the peri-implantation period in pigs. We performed in situ hybridization and immunohistochemistry using conceptus on Days 12 and 15 of pregnancy. CYP19A1 were detected mainly in trophectoderm of conceptus on Days 12 and 15 of pregnancy. IL1B was expressed in trophectoderm of Day 12, but not Days 15. IFND mRNA and protein were localized to trophectoderm and endoderm of Days 12 and 15 with stronger immunostaining signal on trophectoderm than endoderm. IFNG mRNA and protein were mainly localized to trophectoderm, but not endoderm, on Days 12 and 15 of pregnancy. These results showed that CYP19A1, IL1B, IFND and IFNG were localized to conceptus, suggesting that these molecules secreted from conceptus during the peri-implantation period are dynamically regulated during conceptus development in pigs. Further study is needed to analyze the function of these molecules in the uterine endometrium during early pregnancy.
Giant Spin-orbit Torques Induced by Orbital Hall Effect
Soogil Lee,Junho Kang,Taekhyeon Lee,Jung-Mok Kim,Dohyoung Kim,Heechan Jang,Eun Kang Park,Dongwook Go,Nyun Jong Lee,Yoshinori Kotani,Yoichi Shiota,Teruo Ono,S. Sonny Rhim,Kyung-Jin Lee,Hyun-Woo Lee,Kab 한국자기학회 2019 한국자기학회 학술연구발표회 논문개요집 Vol.29 No.2
( Soogil Hong ),( Eui Hwan Choi ),( Keun Pil Kim ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.7
Condensin is not only responsible for chromosome condensation, but is also involved in double-strand break (DSB) processing in the cell cycle. During meiosis, the condensin complexserves as a component of the meiotic chromosome axis, and mediates both proper assembly of the synaptonemal complex and DSB repair, in order to ensure proper homologous chromosome segregation. Here, we used the budding yeast Saccharomyces cerevisiae to showthat condensin participates in a variety of chromosome organization processes and exhibits crucial molecular functions that contribute to meiotic recombination during meiotic prophase I. We demonstrate that Ycs4 is required for efficient DSB formation and establishing homolog bias at the early stage of meiotic prophase I, which allows efficient formation of interhomolog recombination products. In the Ycs4 meiosis-specific allele (ycs4S), interhomolog products were formed at substantial levels, but with the same reduction in crossovers and noncrossovers. We further show that, in prophase chromosomal events, ycs4S relieved the defects in the progression of recombination interactions induced as a result of the absence of Rec8. These results suggest that condensin is a crucial coordinator of the recombination process and chromosome organization during meiosis.