우리 나라 都市와 農村地方의 母乳授乳 實態에 關한 調査硏究 : 全南地方을 中心으로

文松洙,具光鍊,金成宜,韓圭炯,羅昌洙 朝鮮大學校 附設 醫學硏究所 1983 The Medical Journal of Chosun University Vol.8 No.1

Human milk is the best source of nutrients for the human infant, and its nutritional and immunologic benefits are now established, In spite of these advantages, the incidence and duration of breast feeding- is decreasing in many part of the world. The purpose of the study is to collect the data on breast feeding practice in rural and urban area of Chullanamdo, Korea and to follow the trend toward breast feeding in fuutre. Between July 1981 and January 1982, 674 mothers with the children under 2 years of age have been interviewed at Out-Patient Department. The breast feeding situation at the time of interviewed was recorded. The percentage of wholly breast-fed in the age group of 0~1, 1-2, 2~3 ,3~4, 4~5, 5~6, 6-12 and 12~24 months were 61.8%, 50.0%, 51.6%, 65.2%, 50.0%, 45.7%, 23.0% and 17.3% respectively. And the percentage of partially breast-fed in the age group of 0~1, 1~2, 2~3, 3~4, 4~5, 5~6, 6~12, and 12~24 months were 29.4%, 33.3%, 25.8%, 17.4%, 34.2%, 39.1%, 8.6% and 80.0% respectively, In the incidence of wholly breast feeding, there was no correlation between deliveries in hospital and deliveries at home attended by midwives or traditional midwives. The most frequent reasons for partially breast-fed in the age group of 0~1, 1~2, 2~3, and 3~4 months were not enough breast milk.

S-447 : Romiplostim is a successful treatment of eltrombopag-resistant refractory immune thrombocytopenia

( Song Ee Park ),( Min Suk Kwon ),( Jae Hyun Tae ),( Hee Jun Kim ),( Ing Yu Hwang ),( Jung Sun Jang ),( Eun Kyung Park ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1

A 52-year-old female was diagnosed with ITP at our hospital in February 1987. Her Platelet count was 4×109/L at diagnosis. She was initially treated splenectomy in April 1987. Since 1987, she was intermittently administered with oral prednisolone. However, No response in her platelet count was observed. September 2009. Blood test indicated severe thrombocytopenia with a platelet count of 4×109/L, a white blood cell count of 22.39×109/L and a hemoglobin level of 12.9 g/dL. The patient was treated with intravenous immunoglobulin (IVIG, 1g/kg/day for 2 days). IVIG treatment was performed 11 times. Oral prednisone was also restarted at a dose of 1 mg /kg/day. However, No response in her platelet count was observed. Treatment with the thrombopoietin receptor (TP069O-R) agonist, eltrombopag at 50 mg/day. Despite the four months the administration Eltombopag, she fell back into the reaction after only 170,000 platelet count is 100,000 or more. Subsequently. another TPO-R agonist, romiplostim, was administered (at a starting dose of 1 μg/kg/week) in place of eltrombopag. Because of the poor response, weekly increases in the dose of romiplostim were required. An increase in the patient`s platelet count was seen at dose 3.7 μg/kg/week. The platelet continued to rapidly increase during the following weeks, up to a maximum count of 352×109/L. During treatment with romiplostim, the patient experienced no specific side effects.

Strain engineering of GaAs/AlGaAs quantum dots grown by droplet epitaxy

Song-ee Lee,Inah Yeo,Kyu Tae Lee,Jihoon Kyhm,Kyung Soo Yi,Tae Geun Kim,Il Ki Han,Jin Dong Song 한국진공학회 2017 한국진공학회 학술발표회초록집 Vol.2017 No.2

Polyurethane-silica hybrid foams from a one-step foaming reaction, coupled with a sol-gel process, for enhanced wound healing

Song, Eun-Ho,Jeong, Seol-Ha,Park, Ji-Ung,Kim, Sukwha,Kim, Hyoun-Ee,Song, Juha Elsevier 2017 Materials Science and Engineering C Vol.79 No.-

<P><B>Abstract</B></P> <P>Polyurethane (PU)-based dressing foams have been widely used due to their excellent water absorption capability, optimal mechanical properties, and unequaled economic advantage. However, the low bioactivity and poor healing capability of PU limit the applications of PU dressings in complex wound healing cases. To resolve this problem, this study was carried out the hybridization of bioactive silica nanoparticles with PU through a one-step foaming reaction that is coupled with the sol-gel process. The hybridization with silica did not affect the intrinsically porous microstructure of PU foams with silica contents of up to 10wt% and where 5–60nm silica nanoparticles were well dispersed in the PU matrix, despite slight agglomerations. The incorporated silica enhanced the mechanical performance of PU by proffering better flexibility and durability as well as maintaining good water absorption capabilities and the WVTR characteristics of pure PU foam. The silica of PU-10wt% Si foams was gradually dissolved and released under physiological conditions during a 14-day immersion period. The <I>in vitro</I> cell attachment and proliferation tests showed significant improvements in terms of the biocompatibility of PU-Si hybrid foams and demonstrated the effects of silica on cell growth. More significantly, the superior healing capability of PU-Si as a wound dressing in comparison to PU-treated wounds was verified through <I>in vivo</I> animal tests. Full-thickness wounds treated with PU-Si foams exhibited faster wound closure rates as well as accelerated collagen and elastin fiber regeneration in newly formed dermis, which was ultimately completely covered by a new epithelial layer. It is clear that PU-Si hybrid foams have considerable potential as a wound dressing material geared for accelerated, superior wound healing.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PU-silica hybrid foams successfully fabricated using a one-step foaming reaction involving the sol-gel process. </LI> <LI> PU-silica hybrid foams with up to 10wt% silica, the hybrid foams exhibited significantly improved mechanical performance. </LI> <LI> Regardless of silica contents, hybrid foams maintain water absorption capabilities of pure PU. </LI> <LI> PU-silica hybrid foams have significantly enhanced biocompatibility and wound healing capabilities compared to pure PU foams. </LI> </UL> </P>

S-445 : Primary B-lymphoblastic lymphoma of gallbladder diagnoseed by laparosscopic cholecystectomy

( Song Ee Park ),( Jae Hyun Tae ),( Min Suk Kwon ),( Hee Jun Kim ),( Eun Kyung Park ),( Ing Yu Hwang ),( Jung Sun Jang ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1

The patient was a 72-year-old man who presented for evaluation of painless hematuria which he stated had been present for at least 1month. At the time of presentation, the patient did not report any systemic symptoms and had no fever, weight loss or dysuria. Computed tomography (CT) also showed several enhancing, sessile polyps in the gall bladder (1.5 cm and smaller). No associated stone or biliary dilation. Since no other abnormality was evident, we performed laparoscopic cholecystectomy. He was diagnosed as having B-cell lymphoblastic lymphoma (B-LBL) after surgical resection of his gall bladder (GB). A gall bladder, measuring 7.5×4.0 cm. The serosal surface is smooth and glistening. The mucosa shows four sessile polypoid lesions, measuring 1.8×1.5 cm, 1.1×0.9 cm, 0.7×0.7 cm, and 0.8×0.7 cm. The surface of the lesions is whitish and firm. No surface ulceration or hemorrhage is noted. The tumor was B-LBL LCA (+), CD20 (focal+), CD79a (+), CD3 (+), CD45RO (+), Bcl-2 (+), Ki-67 (30%). After the surgery, metastaric work-up including CT scan of the chest, positron emission tomography (PET) and bone marrow biopsy was performed. The PET revealed an increased fluorodeoxyglucose-uptake in the left maxilla, left mandible, right humerus, T12 and lt mandible mass. The clinical course suggested GB tumor was growth of the B-LBL. The definitive pathological diagnosis was B-LBL, stage IV. Systemic chemotherapy was started and subsequent response in size of the lt mandible mass. Since lymphomas of GB are exceedingly rare, the differential diagnosis would be difficult.

Case Report : Estrogen Antagonist and Development of Macular Hole

( Song Ee Chung ),( Seong Wook Kim ),( Hye Won Chung ),( Se Woong Kang ) 대한안과학회 2010 Korean Journal of Ophthalmology Vol.24 No.5

To describe the clinical and optical coherence tomography (OCT) features of a macular hole (MH) or its precursor lesion in patients treated with systemic antiestrogen agents. We reviewed the medical history of the patient, ophthalmic examination, and both fundus and OCT findings. Three female patients receiving antiestrogen therapy sought treatment for visual disturbance. All of the patients showed foveal cystic changes with outer retinal defect upon OCT. Visual improvement was achieved through surgery for the treatment of MH in two patients. Antiestrogen therapy may result in MH or its precursor lesion, in addition to perifoveal refractile deposits. OCT examination would be helpful for early detection in such cases.

Extraction of Gelatin from Fish Processing By-product and Preparation of Its Nano-clay Composite Films

Song-Ee Beak,Ka-Yeon Lee,Hyeri Kim,Kyung Bin Song 한국식품영양과학회 2016 한국식품영양과학회 학술대회발표집 Vol.2016 No.10

Original Article : Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes

( Song Ee Chung ),( Dong Hui Lim ),( Se Woong Kang ),( Young Hee Yoon ),( Ju Byung Chae ),( In Ho Roh ) 대한안과학회 2010 Korean Journal of Ophthalmology Vol.24 No.4

Purpose: To identify the correlation between preoperative optical coherence tomography (OCT) features and postoperative visual outcomes in eyes with idiopathic macular holes (MHs). Methods: Data from 55 eyes with idiopathic MHs which had been sealed by vitrectomy were retrospectively reviewed. Correlation analysis was conducted between postoperative visual acuity (Vpostop, logarithm of the minimum angle of resolution [logMAR]) and preoperative factors, including four OCT parameters: the anticipated length (A) devoid of photoreceptors after hole closure, MH height (B), MH size (C), and the grading (D) of the viability of detached photoreceptors. Additionally, the formula for the prediction of visual outcome was deduced. Results: Vpostop was determined to be significantly correlated with the preoperative visual acuity (Vpreop) and OCT parameters A, C, and D (p<0.001). Based on the correlation, the formula for the prediction of Vpostop was derived from the most accurate regression analysis: Vpostop=0.248×Vpreop+1.1×10-6×A2-0.121×D+0.19. Conclusions: The length and viability of detached photoreceptors are significant preoperative OCT features for predicting visual prognosis. This suggests that, regardless of the MH size and symptom duration, active surgical intervention should be encouraged, particularly if the MH exhibits good viability in the detached photoreceptor layer.

Stable Generation of Neural Precursor Cells from Human Embryonic Stem Cells

( Song Ee Lee ),( Mira Park ),( Na Yeon Lee ),( Byoung Gi Chun ),( Seong Jun Choi ),( Ji Hwan Song ) 한국조직공학과 재생의학회 2008 조직공학과 재생의학 Vol.5 No.2

Human embryonic stem cells(hESCs) have the capacity to selfrenew and to differentiate into all cell types in the body. For this reason, they have been regarded as the ideal sources for cell replacement therapy. In this study, we explored the optimal conditions for neuronal differentiation of hESCs, by coculturing with PA6 stromal cells. We found that neural precursor cells(hESCNPs) can be stably generated by coculturing with PA6, which were confirmed by morphology and immunocytochemical methods. We also established an optimal culture condition for hESCNPs, which allows a longterm proliferation and a largescale expansion of hESCNPs. Considering the developmental potential of hESCNPs, we speculate that they can serve as useful cell sources for treating various neurological diseases, such as stroke.

Case Reports : A Developmental Mechanism of Spontaneous Reattachment in Rhegmatogenous Retinal Detachment

( Song Ee Chung ),( Se Woong Kang ),( Chan Hui Yi ) 대한안과학회 2012 Korean Journal of Ophthalmology Vol.26 No.2

This retrospective observational case series on eyes from three patients was done to elucidate the developmental mechanism of spontaneous reattachment of rhegmatogenous retinal detachment (SRRRD). The study eyes of each patients showed evidence of retinal break and diffuse retinal pigmentary change. Ultrasound biomicroscopic examination revealed vitreous fibers attached to the area around the retinal break. Posterior vitreous attachment was confirmed in each eye. A thin fibrovascular membrane incompletely sealing the retinal break was noted in one case. We suggest that the vitreous attachment around the retinal break and the sealing of the break with adjacent vitreous fibers seem to be involved in the developmental mechanism of SRRRD.