이청준의 「눈길」연구

송준호(Song Jun-ho) 국어문학회 2017 국어문학 Vol.65 No.-

이청준의 단편소설 「눈길」을 대상으로 작중인물의 갈등과 관계변화 과정이 ‘집’과 ‘길’의 공간 모티브와 결합되는 양상을 해명한다. ‘집’에서는 소멸과 재생의 이미지가 동시에 드러난다. 이 소설의 공간적 배경으로서 ‘집’은 작중인물이 어린 시절에 살던 집과 현재 어머니가 살고 있는 집으로 나누어진다. 옛집은 기존에 유지되어 왔던 가족관계의 파탄을 상징한다. 현재의 집은 소멸의 공간 이미지를 띤다. 하지만 그 안에서 벌어지는 어머니와 아내의 대화를 통해 파괴되었던 모자관계의 원형을 회복한다는 점에서 그건 재생의 공간 모티브라고 볼 수 있다. ‘길’은 이동의 속성을 띤 공간으로서 작중인물의 존재론적 전환을 가능하게 하는 공간 모티브다. ‘나’가 옛집을 찾아간 길은 탐색을 유도하는 공간이다. 그곳에서 하룻밤을 지냄으로써 주인공은 미성숙 단계에서 벗어나 성년의 인식을 갖게 된다. 또한 새벽까지 이어지는 아내와 어머니의 대화는 현재와 과거를 연결하는 시간적이고 심리적인 길로서 ‘나’를 존재론적 전환으로 이끄는 구실을 한다는 점에서 중요하다. 길을 따라 과거의 시간으로 떠난 ‘나’는 비로소 어머니와 화해의 단계에 이른다. 소설의 공간적 배경은 독자의 감각을 자극해서 의미를 형성하는 데 직접적으로 작용한다는 점에서 중요하게 다루어져야 한다. 또한 공간의 연구는 작품을 깊고 다양하게 해석할 수 있는 가능성을 제시한다는 점에서 앞으로도 이 분야에 대한 연구는 지속되어야 한다. This study focuses on initiation structure of contemporary Korean novel. Especially initiation structure is one of rites of passage in myths. In order to clarify, contemporary Korean novel’s initiation structure, this paper analyzed the various symbols employed in Lee Cheong Jun’s 「Snowy Road(눈길)」. As symbolism in story has a close connection with the concept of archetype, I accommodated archetypal criticism to analyze the works in the paper. So this paper started by viewing the concept of symbolism of house and road. House and road of 「Snowy Road(눈길)」symbolized death and rebirth of characters.

ERK1/2 activation in quercetin-treated BEAS-2B cell plays a role in Nrf2-driven HO-1 expression

이윤진,Jun-Hwan Song,Myung-Ho Oh,Yong-Jin Lee,김용배,Jae-Hyuk Im,이상한 대한독성 유전단백체 학회 2011 Molecular & cellular toxicology Vol.7 No.4

Quercetin, a member of the flavonoids,has been heralded as chemopreventive agent, generally because of its free radical-scavenging and antiproliferative activities. In this process, NF-E2-related factor-2 (Nrf2) plays a role in protecting cells from oxidative damage; however, the exact mechanisms in which bronchial epithelial cells respond to quercetin by activating Nrf2 are not fully understood. Here, we report the role of extracellular signal-regulated kinase (ERK) activation in response to quercetin. Quercetin treatment decreased the viability of human bronchial epithelial BEAS-2B cells in a dose- and time-dependent manner. ERK1/2 was activated within 10 min of quercetin addition and then remained increased above control level throughout 48 h, whereas AKT phosphorylation was suppressed from the first 1 h of quercetin treatment. Inhibition of Erk1/2 phosphorylation attenuated quercetin-induced loss of cell viability. Nrf2levels in both nuclear and whole cell lysates increased after quercetin treatment and was accompanied by the increase of heme oxygenase-1 (HO-1) protein level,indicating that increased HO-1 expression is Nrf2-mediated. Activation of the Nrf2/HO-1 system after quercetin treatment was suppressed by the pretreatment with MEK inhibitor, PD98059. Also, silencing Nrf2 with siRNA decreased cell viability and augmented cytotoxic effect of anticancer drug LBH589. Overall, our results indicate that quercetin induces the up-regulation of Nrf2-mediated HO-1 expression, at least in part, via MEK/ERK1/2 signaling, as an adaptive mechanism which may provide advantages for cell proliferation and enhance survival despite endogenous and/or exogenous oxidative insults.

수도권 내륙화물기지 신설에 따른 효과 분석

장준석(Jun-Seok Jang),이준(Jun Lee),박재현(Jae-Hyun Park),송민호(Min-Ho Song),권용장(Yong-Jang Kwon) 한국철도학회 2011 한국철도학회 학술발표대회논문집 Vol.2011 No.10

내륙물류기지는 도로 철도 항만 공항 간의 연계운송 및 복합운송을 할 수 있는 규모와 시설을 갖춘 대규모 물류처리 시설을 지칭하며 화물의 대량수송으로 인한 물류비절감을 위하여 전국의 주요 물류 거점에 구축하여 운영을 하고 있다. 하지만 수도권 물류를 처리하는 유일한 화물거점시설인 의왕ICD의 경우 2015년 이전에 물류시설의 용량이 한계치에 도달할 것으로 예상되어 추가적인 시설개량이나 다른 수도권 물류처리시설 신설이 필요한 실정이다. 특히 입지적으로 부지 확장에 대하여 주변 여건상 한계가 있으므로 물류처리시설 신설로 인한 용량 및 처리능력 향상이 요구된다. 또한 현재 남북 간 화물철도운송에 대한 관심이 증대됨에 따라 향후 화물운송은 도로와 선박에서 철도로 물량전환이 가능할 것으로 판단되나 이들 살화물의 주요 수요지인 수도권(서북부 지역)에는 이 물동량을 처리 및 보관 할 수 있는 화물역과 물류기지가 부재하여 이들 확보할 필요가 있다. 따라서 본 연구는 서해안축 신규 물류기지(송산역 안중역)와 서북부 신규 물류기지(대곡역) 신설을 통하여 수도권 물동량 급증에 따른 철도 선로용량 부족 문제 해소방안과 남북 간의 효율적인 철도수송 수도권 철도화물의 분산효과 등을 검토함으로써 원활한 철도수송서비스를 제공하여 물류비를 절감하는 데 그 목적이 있다. The inland logistics center is a large scale of logistics facility that enables roads rails ports and airports to carry out chained-transports and combined-transports and the logistics center are established at the main logistics posts in order to reduce the cost of transport by mass transportation. However it is expected that the capacity of Euiwang ICD the only inland logistics centers in the capital area will reach its limit before 2015 so it is required to establish another stations or to improve the existing facility. Especially in case of Euiwang ICD the expansion of the center is not possible because of its position so it is required to establish new logistics centers in other places in order to raise the capacity of transport. Therefore this study suggests to establish new metropolitan logistics centers on the western coast line in order to solve the problem of shortage of tract capacity that is brought on by the newly established inland logistics centers on the axis of the western coastline (Song-san Station and An-jung Station) and analyzes how the new logistics center will distribute railroad cargoes. By these this study contributes to reduce the cost of transport by providing smooth railroad transport service.

원위 경골 간부 골절에서 최소 침습적 경피적 금속판 고정술과 관혈적 금속판 고정술의 비교

유성호 ( Seong Ho Yoo ),안성준 ( Seong Jun Ahn ),송무호 ( Moo Ho Song ),김부환 ( Bu Hwan Kim ),이민수 ( Min Soo Lee ),박종하 ( Jong Ha Park ) 대한골절학회 2006 대한골절학회지 Vol.19 No.1

목적: 경골 원위부 골절의 치료에 있어 최소 침습적금속판 고정술과 관혈적 고정술에 대한 비교를 통한 효율성에 대한 연구고찰을 하고자 한다. 대상 및 방법: 2001년 6월부터 2004년 6월까지 경골 원위부 골절에 대하여 수술을 시행한 최소 1년 이상의 추시가 가능하였던 30예 중 최소 침습적 금속판 고정술을 시행한 15예를 A군, 관혈적 금속판 고정술을 시행한 15예를 B군으로 나누어 수술시간, 술 후 재활, 술 후 운동범위, 동통에 대하여 McLennan과 Ungersma의 기준을 이용한 임상평가, 술 후 염증반응에 대한 C-반응성 단백 및 술 후 합병증을 후향적으로 비교 분석하였다. 결과: A군과 B군의 수술시간은 각각 63분 (45∼105)/129분 (80∼120), 능동적 관절 운동가능시기는 8.3일 (6∼14)/15.8일 (13∼21), McLennan과 Ungersma의 기준에 의한 임상평가는 두 군 모두에서 대부분 양호 이상의 결과를 보였으나, B군에서는 보통 1예가 있었다. 술 후 3일, 7일째 각각 시행한 CRP는 A군에서는 4.0 mg% (범위: 0.9∼7.2)/0.5 mg% (0.1∼1.5), B군에서는 7.97 mg% (2.8∼14.6)/1.0 mg% (0.3∼1.6)로 A군에서 조직손상이 적고 회복이 빨랐다. 술 후 합병증으로는 A군에서는 표재성 감염 1예와 5도 이상의 족관절 외반변형 1예가 있었고, B군에서는 표재성 감염 1예, 감염성 불유합 1예와 10도 미만의 족관절 배굴장애를 보이는 경우가 2예 있었다. 결론: 경골 원위부 골절의 수술적 치료에서 최소 침습적 금속판 고정술이 관혈적 고정술에 비해 조직의 염증반응과 합병증이 적고 수술시간 및 술 후 재활 등에서 보다 효율적인 술식으로 사료된다. Purpose: To evaluate the efficacy of the surgical treatment through the comparison of MIPPO vs open plate fixation in the treatment of the distal tibia fracture retrospectively. Materials and Methods: 30 patients with distal tibia fracture from Jun. 2001 to Jun. 2004 were divided into two groups depending on the surgical method. Minimum follow up was 12 months. Group A consisted of 15 patients treated with MIPPO, Group B was 15 patients treated with open plate fixation. The clinical outcomes were evaluated retrospectively from operation time, rehabilitation, ROM, interval change of postoperative CRP to assess postoperative inflammatory reaction, postoperative complications and clinical result with the use of McLennan and Ungersma criteria. Results: There were no significant differences in clinical result by McLennan and Ungersma criteria in both groups. The postoperative 3 days and 7 days CRP were 4.0 mg% (0.9∼7.2)/0.5 mg% (0.1∼1.5) in group A and 7.97 mg% (2.8∼14.6)/1.0 mg% (0.3∼1.6) in group B, shows more minimal tissue injury and early recovery in group A. Operation time in group A was shorter than group B. Normal recovery of ROM was quicker in Group A. In complications, group A showed one superficial infection and one angular deformity and group B showed one superficial infection, one infected nonunion and two ankle stiffness. Conclusion: There were no significant differences in clinical result and bony union. MIPPO technique is superior to group B in view of the minimal tissue injury, complications, operation time and postoperative rehabilitation.

가상공간의 가공 공정과 상태 구현에 관한 연구

이수훈,김봉석,홍민성,김종민,JUN NI,박상호,송준엽,이창우,하태호 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

This paper presents virtual machining system in order to realize turning process in virtual space. A reliable virtual turning process simulation was developed based on the surface shaping system which is capable of considering geometric model, thermal error model, and vibration model. Accuracy of surface shape resulting from proposed machining simulator was verified experimentally. This paper also developed the watchdog agent that continuously assessed, diagnosed, and predicted performance of products and machines in machining. The Watchdog agent extracted feature signal using time-frequency analysis among various signals from multi-sensor and evaluated machining condition using performance confidence value.

질트리코모나스 (Trichomonas vaginalis)의 항원성 분석에 관한 연구

송준호,임미혜,민득영 한양대학교 의과대학 1991 한양의대 학술지 Vol.11 No.1

Trichomonas vaginalis is a flagellated protozoan parasite which is a major causative organism of vaginitis in women and of urethritis in men. In the present study to elucidate the immune response involving host-parasite interrelationship, antigen analysis of this parasite was carried out using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), enzyme-linked immunoelec-trotransfer blot (EITB) and enzyme-linked immunosorbent assay (ELISA). For the study sera from 21 Trichomonas vaginalis patients, 7 other parasite-infected patients, 2 candidiasis patients, 17 healthy students and 4 young children under 5 years old were subjected and the results obtained were as follows: 1. In SDS-PAGE, sonicated total antigens from 5 strains of T. vaginalis revealed 20-25 protein profiles ranging 14-110 KDa in molecular weight. 2. On EITB probed with sera from trichomoniasis, immunogenic bands was recognized. But in children the bands of 15, 18 and 23KDa were not seen. 4. In high performance gel filtration chromatography of sonicated total antigen of T. vaginalis, 10 peaks were identified as in ranging 2.6-155 KDa. 5. In ELISA using fractions of 10 peaks from high performance gel filtration chromatography as antigens, values of IgG and IgM antibodies of trichomoniasis patients were significantly higher than those of healthy controls (P〈0.001 or P〈0.001-0.002 respectively). In conclusion with results obtained in the present styudy it is assumed that immunogenic bands in 15, 18and 23KDa on SES-PABE may connote the important significance on immune response in T. vaginalis infection.

인간의 내면과 관계의 그물망 : 소설의 인물 Character of Novel

송준호 又石大學校 人文科學硏究所 1997 人文論叢 Vol.4 No.-

방문한 격자점을 배방문하는 취보

宋俊鎬 서울市立大學校 1983 論文集 Vol.17 No.-

We present here the probabilities of starting at 0 and ultimately arriving at ℓwith intermediate visits to the set of points in one dimensional non-symmetric random walks. Quantitative behaviors for the probabilities of visits to a set of points revisited are as follows :F??(ℓ,1)<F??(ℓ,1) <F??(0,1), n≤ℓ F??(ℓ,1)<F??(ℓ,1)<F??(0,1)<F??(ℓ,1)=F(ℓ,1), n>ℓ F??(ℓ,1)<F??(ℓ,1)=F(ℓ,1), for q(=p(-1)), O<R<ℓ. Most of the results in this paper have been derived by the method of the Green's functions.

寫實主義 小說의 象徵論的 解明 : 羅稻香 小說을 中心으로

宋俊鎬 又石大學校 1995 論文集 Vol.17 No.-

흰쥐에서 음경발기 평가의 척도로서 음경해면체내압측정술 확립

송윤섭,김용준,이광우,김준모,문기혁,박영호,민영기,유형균,김형건 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Purpose: Because studies about the control of penile erection at the entral nervous system was dependent on the animal experiments, establishment of measuring penile erection is important to evaluate the effects changes at the central nervous system on the penile erection. Intracavernous pressure measurement in rats has been introduced as a suitable index for the evaluation of penile erection but this method is invasive and technically difficult. So, we established the intracavernous pressure measurement in rats as the experimental index for penile erection. Materials and Methods: 42 male adult Sprague-Dawley rats (250-300gm) were divided to saline or papaverine treated group. Rats were placed on a heating table to maintain their body temparature and anesthetized with 50mg/kg of pentobarbital sodium by intraperitoneal injection. A cannula was inserted to the left carotid artery to measure systemic blood pressure. Saline (0.05, 0.1ml), papaverine(0.05, 0.1, 0.25, 0.5, 1.0, 2.0mg) were injected intracavernously via 26 guage needle filled with saline or papaverine which connected to pressure transducer and polygraph was inserted into the corpus cavernosum on one side to inject the drug and to measure intracavernous presure. Results: Properly executed insertion and intracavernous administration produced a instantaneous but transient rise in intracavernous pressure that substantially stabilized and maintained at 5.4±0.4mmHg. Intracavernous pressure and duration of penile blood flow following intracavernous injection of papaverine are increased comared to those of saline. Conclusions: Monitoring intracavernous pressure in rats represents a suitable index for the evaluation of penile erection in small laboratory animals.