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Cardiorenal syndrome and vitamin D receptor activation in chronic kidney disease
( Sirous Darabian ),( Manoch Rattanasompattiku ),( Parta Hatamizadeh ),( Suphamai Bunnapradist ),( Matthew J. Budoff ),( Csaba P. Kovesdy ),( Kamyar Kalantar Zadeh ) 대한신장학회 2012 Kidney Research and Clinical Practice Vol.31 No.1
Cardiorenal syndrome (CRS) refers to a constellation of conditions whereby heart and kidney diseases are pathophysiologically connected. For clinical purposes, it would be more appropriate to emphasize the pathophysiological pathways to classify CRS into: (1) hemodynamic, (2) atherosclerotic, (3) uremic, (4) neurohumoral, (5) anemic·hematologic, (6) inflammatory·oxidative, (7) vitamin D receptor (VDR) and/or FGF23-, and (8) multifactorial CRS. In recent years, there have been a preponderance data indicating that vitamin D and VDR play an important role in the combination of renal and cardiac diseases. This review focuses on some important findings about VDR activation and its role in CRS, which exists frequently in chronic kidney disease patients and is a main cause of morbidity and mortality. Pathophysiological pathways related to suboptimal or defective VDR activation may play a role in causing or aggravating CRS. VDR activation using newer agents including vitamin D mimetics (such as paricalcitol and maxacalcitol) are promising agents, which may be related to their selectivity in activating VDR by means of attracting different post-D-complex cofactors. Some, but not all, studies have confirmed the survival advantages of D-mimetics as compared to non-selective VDR activators. Higher doses of D-mimetic per unit of parathyroid hormone (paricalcitol to parathyroid hormone ratio) is associated with greater survival, and the survival advantages of African American dialysis patients could be explained by higher doses of paricalcitol (410 mg/week). More studies are needed to verify these data and to explore additional avenues for CRS management via modulating VDR pathway.
Sirous Aghajari,Hossein Showkati,Karim Abedi 국제구조공학회 2011 Structural Engineering and Mechanics, An Int'l Jou Vol.39 No.6
The buckling capacity of the cylindrical shells depends on two geometric ratios of L/R and R/t. However the effect of thickness variation on the behavior of the shells is more complicated and the buckling strength of them is sensitive to the magnitude and shape of geometric imperfections. In this paper the effects of thickness variation and geometric imperfections on the buckling and postbuckling behavior of cylindrical shells are experimentally investigated. The obtained results are presented under the effect of uniform lateral pressure. It is found in this investigation that the buckling mode can be generated in the whole length of the shell, if the thickness variation is low.
Sirous-Rezaei, Pouya,Jae, Jungho,Ha, Jeong-Myeong,Ko, Chang Hyun,Kim, Ji Man,Jeon, Jong-Ki,Park, Young-Kwon The Royal Society of Chemistry 2018 GREEN CHEMISTRY Vol.20 No.7
<P>Strong adsorption of phenolics on zeolite acid sites causes high trapping inside zeolite channels and low catalytic activity of zeolite-supported catalysts in atmospheric pressure hydrodeoxygenation (HDO) of lignin-derived phenolics. This adsorption is more severe at low temperatures, and restricts the atmospheric HDO of phenolics to high reaction temperatures. The purpose of this research was to develop a catalyst with low phenolic trapping potential and high HDO efficiency under mild reaction conditions. Among the tested catalysts (Fe/HBeta, FeReOx/HBeta, Fe/MCM-41, ReOx/MCM-41, FeReOx/MCM-41, Fe/ZrO2 and FeReOx/ZrO2), the novel catalyst of FeReOx/ZrO2 exhibited the highest catalytic efficiency for mild-condition (pressure: 1 atm and temperature <350 °C) HDO of phenolics (guaiacol, <I>m</I>-cresol and anisole), and led to the selective production of BTX aromatics. Compared to Fe/HBeta(38) as a zeolite-supported catalyst, FeReOx/ZrO2 displayed remarkably enhanced performance, and its catalytic activity for the HDO of <I>m</I>-cresol at 350 °C was almost twice higher than that of Fe/HBeta(38) at 500 °C. Importantly, FeReOx/ZrO2 revealed a high HDO efficiency (BTX yield of 50.5 wt% with phenolic trapping below 5 wt%) at a low temperature of 250 °C, while Fe/HBeta(38) almost lost its entire catalytic activity at this temperature, and gave a low BTX yield of 3.0 wt% with a high trapped phenolic yield of 83.1 wt%. The remarkable catalytic activity of FeReOx/ZrO2 in the HDO of phenolics at atmospheric pressure and temperatures as low as 250 °C is a result of its mesoporosity and oxophilicity as well as its well-balanced acidity induced by both rhenium oxide and zirconia support causing a high dehydration efficiency.</P>
배기가스 상에서 산화제를 이용한 SOx, NOx 동시 제거
( Pouya Sirous Rezaei ),황유진,정재훈,김지희,박영권 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.0
SOx, NOx는 대기중의 2차 생성 미세먼지를 발생시키는 전구물질이며 도색 공장, 유리 공장 등과 같은 중소형 연소시설에서 1차 미세먼지와 함께 다량 배출되고 있다. 중소형 연소시설은 주거지역과 인접하고 영세 사업장이 많아 오염 체감도가 크지만 현재 SOx, NOx의 처리는 각각 단일 설비로 되어있어 운전상, 경제상의 문제 등을 가지고 있다. 최근에 한 개의 시스템에 SOx, NOx를 동시에 처리하고자 하는 연구가 진행 중이다. 따라서 본 연구에서는 배기가스 분위기인 SOx, NOx에 산화제(O3 등)를 이용하여 동시에 제거하는 실험을 진행하였고 실험조건(산화제 농도, 반응기 수 등)의 변화에 따른 SOx, NOx 제거율을 확인하였다. <sup>**</sup> 본 연구는 2017년도 정부(과학기술정보통신부, 환경부, 보건복지부)의 재원으로 한국연구재단-미세먼지 국가전략프로젝트사업의 지원을 받아 수행된 기초연구 사업임(No. 2017M3D8A1092029).
Mesoporous 촉매 지지체를 활용한 온화조건의 수첨탈산소반응
( Pouya Sirous Rezaei ),김지희,정재훈,박영권 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.0
바이오매스 열분해 공정을 통해 얻어지는 바이오오일은 현재 액체 연료로의 전환을 통해 에너지 공급 문제를 완화할 수 있는 잠재력이 높은 물질로서 이에 대한 upgrading 공정을 연구하였다. 기존 원료 feedstock 내에 기본적으로 수분 및 구조적으로 산소가 포함되어있어 바이오오일의 화학산업으로의 적용을 위해서는 필수적으로 이러한 산소 함량을 낮추기위한 upgrading 공정이 요구된다. 따라서 바이오오일의 성능 향상을 위해 수첨탈산소(Hydrodeoxygenation) 반응을 적용하였으며, 그 결과 높은 산소함량으로 인한 낮은 발열량, 산화로 인한 안정성 약화 및 유기산에 대한 높은 함량으로 인한 부식성이 높다는 문제점을 해결할 뿐 아니라 고부가가치 물질에 대한 선택도가 향상됨을 확인하였다. 본 반응을 위한 촉매로는 Mesoporous 촉매에 금속활성종을 담지하여 반응효율을 향상시키고자 하였다. <sup>**</sup> This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Education(2017R1D1A1B03028818).
Amini Sirous,Mohamadzamani Davood,Javidan Seyed Mohamad 한국농업기계학회 2022 바이오시스템공학 Vol.47 No.3
Purpose This research investigates the main specifications of eggshell which are the thickness of the shell and its strength. For this purpose, random sampling was implemented on 180 fresh and healthy eggs of Bovance breed produced at Ghazvin province agricultural jihad organization’s training center. Methods To measure the shell thickness, four methods, dial gauge, ultrasound waves, micro-meter and photometer, were applied. Due to its precision, the indicator hour destructive measurement method was selected as the control method. Results By analyzing and comparing data collected through 4 methods in the research, a significant difference between measurement methods was revealed. Moreover, comparing the measurement methods with the control method (dial gauge), the lowest measurement error was that of the ultrasound wave measurement method with 7.1% and the highest was that of the photometer method with 15.7%. Furthermore, regression equations are determined for the referred measurement methods with the shell strength. Conclusion It was observed that the ultrasound method compared to other methods proposed in this study is more accurate for measuring the thickness of the eggshell non-destructively. Therefore, the non-destructive ultrasonic measurement method can be a suitable alternative to these methods due to the proximity of the measured values to non-destructive, direct, and accurate destructive methods. Since the ultrasound method is a fast and relatively inexpensive method, this method can be used in the quality grading process of eggs.
Aghajari, Sirous,Showkati, Hossein,Abedi, Karim Techno-Press 2011 Structural Engineering and Mechanics, An Int'l Jou Vol.39 No.6
The buckling capacity of the cylindrical shells depends on two geometric ratios of L/R and R/t. However the effect of thickness variation on the behavior of the shells is more complicated and the buckling strength of them is sensitive to the magnitude and shape of geometric imperfections. In this paper the effects of thickness variation and geometric imperfections on the buckling and postbuckling behavior of cylindrical shells are experimentally investigated. The obtained results are presented under the effect of uniform lateral pressure. It is found in this investigation that the buckling mode can be generated in the whole length of the shell, if the thickness variation is low.
Rezaei, Pouya Sirous,Oh, Daejun,Hong, Yeojin,Kim, Young-Min,Jae, Jungho,Jung, Sang-Chul,Jeon, Jong-Ki,Park, Young-Kwon Pergamon 2017 Energy Conversion and Management Vol. No.
<P><B>Abstract</B></P> <P>Catalytic co-pyrolysis of biomass and hydrogen-rich materials is an effective approach for enhancing the production of bio-based hydrocarbons. In this work, mesoporous solid acid materials, such as hierarchical mesoporous MFI (meso MFI), hierarchical mesoporous Y (meso Y) and Al-SBA-15, were used as the catalysts for the catalytic co-pyrolysis of yellow poplar (YP) and high-density polyethylene (HDPE). Among three catalysts, meso MFI revealed the highest catalytic efficiency for the production of aromatic hydrocarbons from catalytic pyrolysis of YP or HDPE due to its effective pore structure, large channels, and high acidity. Moreover, meso MFI showed the highest synergistic formation of aromatic hydrocarbons during the catalytic co-pyrolysis of YP and HDPE as a result of hydrogen donating effect of HDPE and catalytic interactions between YP- and HDPE-derived pyrolyzates. The amounts of solid residue obtained from the catalytic co-pyrolysis of YP and HDPE over meso MFI were also much lower than their theoretical yields.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Meso-MFI catalyzed pyrolysis of yellow poplar gave high aromatic hydrocarbon yield. </LI> <LI> MFI pore structure, large pore size and strong acidity cause high aromatization. </LI> <LI> Significant synergy occurred between yellow poplar and HDPE over meso-MFI catalyst. </LI> <LI> Catalytic pyrolysis efficiency is a strong function of H/C<SUB>eff</SUB> ratio of feedstock. </LI> </UL> </P>