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      • Supporting Preschool Children’s Early Writing with Self-Regulated Learning Strategies

        Siew Kim Siew,Mariani Binti Md Nor 환태평양유아교육연구학회 2019 Asia-Pacific journal of research in early childhoo Vol.13 No.2

        Research suggests that early writing is crucial in the development of young children’s literacy skills and links to their conventional literacy outcomes in elementary school and beyond. In order to enhance the will and the skills to express thoughts explicitly and effectively in early writing among preschool children, self-regulated learning (SRL) was suggested. This experimental study involved seventy-five preschool children, aged from five to six years old in Malaysia, aimed to investigate the effectiveness of SRL strategies on early writing performance. In this study, quantitative data collection was engaged and supported with qualitative data through interviews to obtain a deep insight of the findings results. Two-way repeated measure ANCOVA was employed and confirmed the effectiveness SRL intervention performance in early writing. In regression analyses, strategy such as planning and goal setting was confirmed as strong predictor for early writing performance. Data from the interview revealed that various SRL strategies were engaged by out-performing children from the experimental group and contributed to their early writing performance. The findings of this research provide a useful insight into early writing instructions in Malaysian context.

      • KCI등재

        Inadequate vitamin D intake among pregnant women in Malaysia based on revised recommended nutrient intakes value and potential dietary strategies to tackle the inadequacy

        Siew Siew Lee,Raman Subramaniam,Maiza Tusimin,King Hwa Ling,Kartini Farah Rahim,Su Peng Loh 한국영양학회 2021 Nutrition Research and Practice Vol.15 No.4

        BACKGROUND/OBJECTIVES: Recently, the recommended nutrient intakes (RNI) for vitamin D for Malaysian aged 1–70 yrs has been revised from 5 μg/day to 15 μg/day. This study is aimed to assess the adequacy of vitamin D intake based on revised RNI and to recommend several dietary strategies to increase total vitamin D intake. SUBJECTS/METHODS: Vitamin D intake from both food and supplement of 217 pregnant women was assessed using a validated food frequency questionnaire. Hypothetical effect of expanded supplementation and food fortifications strategies were modelled using the consumption data. RESULTS: The results revealed that more than half (67.7%) of pregnant women had inadequate vitamin D intake (RNI < 15 μg/day). The modelling results demonstrated the potential of universal provision of 10 μg/day of multivitamins supplements in increasing vitamin D intake. Moreover, mandatory fortification of both milk and malted drink at single level of 5 μg/serving would lead to increase in vitamin D intake of Malaysians, particularly pregnant women. CONCLUSIONS: The outcome of this study can be used as a reference for public health professionals to re-evaluate the existing Malaysian food fortification policies and supplementation recommendation for vitamin D for pregnant women.

      • KCI등재

        A summary of the Malaysian Clinical Practice Guidelines on the management of postmenopausal osteoporosis, 2022

        Terence Ing Wei Ong,Lee Ling Lim,Siew Pheng Chan,Winnie Siew Swee Chee,Alan Swee Hock Ch’ng,Elizabeth Gar Mit Chong,Premitha Damodaran,Fen Lee Hew,Luqman bin Ibrahim,Hui Min Khor,Pauline Siew Mei Lai 대한골다공증학회 2023 Osteoporosis and Sarcopenia Vol.9 No.2

        Objectives: The aim of these Clinical Practice Guidelines is to provide evidence-based recommendations to assist healthcare providers in the screening, diagnosis and management of patients with postmenopausal osteoporosis (OP). Methods: A list of key clinical questions on the assessment, diagnosis and treatment of OP was formulated. A literature search using the PubMed, Medline, Cochrane Databases of Systematic Reviews, and OVID electronic databases identified all relevant articles on OP based on the key clinical questions, from 2014 onwards, to update from the 2015 edition. The articles were graded using the SIGN50 format. For each statement, studies with the highest level of evidence were used to frame the recommendation. Results: This article summarizes the diagnostic and treatment pathways for postmenopausal OP. Risk stratification of patients with OP encompasses clinical risk factors, bone mineral density measurements and FRAX risk estimates. Non-pharmacological measures including adequate calcium and vitamin D, regular exercise and falls prevention are recommended. Pharmacological measures depend on patients’ fracture risk status. Very high-risk individuals are recommended for treatment with an anabolic agent, if available, followed by an anti-resorptive agent. Alternatively, parenteral anti-resorptive agents can be used. High-risk individuals should be treated with anti-resorptive agents. In low-risk individuals, menopausal hormone replacement or selective estrogen receptor modulators can be used, if indicated. Patients should be assessed regularly to monitor treatment response and treatment adjusted, as appropriate.

      • SCOPUSKCI등재

        Anion-Dependent Exocyclic Mercury(II) Coordination Polymers of Bis-dithiamacrocycle

        Siewe, Arlette Deukam,Kim, Seulgi,Choi, Kyu Seong,Lee, Shim Sung Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.12

        Synthesis and structural characterization of mercury(II) halides and perchlorate complexes (1-4) of bis-$OS_2$-macrocycle (L) are reported. L reacts with mercury(II) chloride and bromide to yield an isostructural 2D coordination polymers with type $[Hg(L)X_2]_n$ (1: X = Cl and 2: X = Br). In 1, each Hg atom which lies outside the cavity is six-coordinate with a distorted octahedral geometry, being bound to four adjacent ligands via monodentate Hg-S bonds and two remaining sites are occupied by two terminal chlorido ligands to form a fishnet-like 2D structure. When reacting with mercury(II) iodide, L afforded a 1D coordination polymer $\{[Hg_2(L)I_4]{\cdot}CHCl_3\}_n$ (3) in which each exocyclic Hg atom is four-coordinate, being bound to two sulfur donors from different ligands doubly bridging the ligand molecules in a head-to-tail mode. The coordination sphere in 3 is completed by two iodo terminal ligands, adopting a distorted tetrahedral geometry. On reacting with mercury(II) perchlorate, L forms solvent-coordinated 1D coordination polymer $\{[Hg_2(L)(DMF)_6](ClO_4)_4{\cdot}2DMF\}_n$ (4) instead of the anion-coordination. In 4, the Hg atom is five-coordinate, being bound to two sulfur donors from two different ligands doubly bridging the ligand molecules in a side-by-side mode to form a ribbon-like 1D structure. The three remaining coordination sites in 4 are completed by three DMF molecules in a monodentate manner. Consequently, the different structures and connectivity patterns for the observed exocyclic coordination polymers depending on the anions used are influenced not only by the coordination ability of the anions but also by anion sizes.

      • KCI등재

        Heat transfer analysis on wafer annealing process in semiconductor multi-wafer furnace using CFD simulation

        Siew Aun Tan,Kok Hwa Yu,Mohd Zulkifly Abdullah 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.6

        This study employs a three-dimensional numerical model to simulate a vertical furnace for wafer annealing process. For a conventional furnace design, it is revealed that the top 5 pieces of the stacked wafers are exposed to lower temperatures, approximately 3-5 % lower than the operating heater temperature. Temperature distribution and the heat losses from the furnace, especially on the heat dissipated through the top header and the process door of the furnace chamber, are examined. To reduce the heat losses, furnace design improvements comprised of a thicker top header and a better thermal insulated process door are recommended. With such implementations, up to 28 % and 22 % reduction of heat dissipation through the top header and the process door, respectively, could be attained. In addition, the design of the boat cover is found to influence the temperature uniformity across the stacked wafers. To attain better temperature uniformity at the top region of stacked wafers, a furnace with a full boat cover is thus recommended.

      • KCI등재

        Real Exchange Rate Dynamics in the Asian Economies: Can Regime Shifts Explain Purchasing Power Parity Puzzles?

        Siew-Voon Soon,Ahmad Zubaidi Baharumshah,Sung K. Ahn 연세대학교 동서문제연구원 2015 Global economic review Vol.44 No.2

        We show that the strong version of the purchasing power parity (PPP) hypothesis holds in most of the US dollar real exchange rates using cointegration method that accounts for breaks in the models. The break dates in seven of the Asian currencies coincide with the two rounds of currency depreciation recorded during the 1997–1998 financial crises. We obtain a mean half-life estimate of about 10 months for PPP to converge to its long-run equilibrium level. Our confidence intervals based on persistence profile approach for the half-lives is much narrower than previous evidence might indicate. Taken together, these results show that mean reversion is stronger than commonly thought.

      • SCOPUSKCI등재

        Preparation and Crystal Structures of Silver(I), Mercury(II), and Lead(II) Complexes of Oxathia-Tribenzo-Macrocycles

        Siewe, Arlette Deukam,Ju, Huiyeong,Lee, Shim Sung Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.3

        An investigation of the coordination behavior of sulfur-containing mixed-donor tribenzo-macrocycles $L^1-L^3$ ($L^1$: 20-membered $O_3S_2$, $L^2$: 20-membered $O_2S_3$, and $L^3$: 23-membered $O_4S_2$) with $d^{10}$-metal ($Ag^+$, $Hg^{2+}$, and $Pb^{2+}$) salts is reported. The X-ray structures of five complexes (1-5) with different structural types and stoichiometries, including mono- to dinuclear species have been determined. Reactions of $L^2$ and $L^3$ with the silver(I) salts ($PF_6{^-}$ and $SCN^-$) afforded two dinuclear 2:2 (metal-to-ligand) complexes with different arrangements: a sandwich-type cyclic dinuclear complex $[Ag_2(L^2)_2](PF_6)_2{\cdot}3CH_2Cl_2$ (1) and a linear dinuclear complex $[Ag_2(L^3)_2(SCN)_2]$ (2), in which two monosilver(I) complex units are linked by an Ag-Ag contact. Reactions of $L^1$ and $L^2$ with mercury(II) salts ($SCN^-$ and $Cl^-$) gave a mononuclear 1:1 complexes $[Hg(L^1)(SCN)_2]$ (3) and $[Hg(L^2)Cl_2]$ (4) with anion coordination in both cases. $L^2$ reacts with lead(II) perchlorate to yield a mononuclear sandwich-type complex $[Pb(L^2)_2(ClO_4)_2]$ (5), giving an overall metal coordination geometry of eight with a square antiprism arrangement. From these results, the effects of the donor variation and the anioncoordination ability on the resulting topologies of the soft metal complexes are discussed.

      • Understanding Passengers’ Perceived Safety and Quality of Journey in AI-based Self-Driving Taxi Services

        Siew Fan Wong,Seoyoun Lee,Younghoon Chang 한국경영정보학회 2021 한국경영정보학회 학술대회논문집 Vol.2021 No.11

        Safety issue is the decisive key to service commercialization for autonomous vehicles. This study examines the relationship between perceived safety and the quality of the journey in AI-based self-driving taxi services. The results will provide scholarly and practical implications to enhance AI-based self-driving taxi services.

      • SCISCIESCOPUS

        In vitro requirement for periostin in B lymphopoiesis

        Siewe, Basile T.,Kalis, Susan L.,Le, Phong T.,Witte, Pamela L.,Choi, Sangdun,Conway, Simon J.,Druschitz, Laurel,Knight, Katherine L. American Society of Hematology 2011 Blood Vol.117 No.14

        <B>Abstract</B><P>B lymphopoiesis arrests in rabbits by 4 months of age. To identify molecules that contribute to this arrest, cDNA-representational difference analysis on BM stromal cells from young and adult rabbits showed that expression of Postn that encodes for the extracellular matrix protein periostin dramatically reduced with age. Postn-small interfering RNA OP9 cells lost their capacity to support B-cell development from rabbit or murine BM cells, and reexpression of periostin restored this potential, indicating an in vitro requirement for periostin in B lymphopoiesis. In our system, we determined that periostin deficiency leads to increased cell death and decreased proliferation of B-lineage progenitors. Further, RGD peptide inhibition of periostin/αvβ3 interaction resulted in a marked decrease in B lymphopoiesis in vitro. Microarray analysis of the Postn-small interfering RNA OP9 cells showed decreased expression of key B-lymphopoietic factors, including IL-7 and CXCL12. In vivo, unidentified molecule(s) probably compensate periostin loss because Postn−/− mice had normal numbers of B-cell progenitors in BM. We conclude that the decline in periostin expression in adult rabbit BM does not solely explain the arrest of B lymphopoiesis. However, the interaction of periostin with αvβ3 on lymphoid progenitors probably provides both proliferative and survival signals for cells in the B-cell development pathway.</P>

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