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E. coli 과량발현을 통한 B형 간염 바이러스 preS1 유도체의 안정한 동위원소 N의 치환
박병관,김세하,한규훈,김선영,홍요정,이시형,한동설,김순종,박진구 木浦大學校基礎科學硏究所 1997 基礎科學硏究誌 Vol.15 No.-
We have used molecular biology technique to label the side chains and backbone of HBV preS1(1-56) with stable isotope (??) during E. coli over-expression and purified the protein to near homogeneity. The expression level of ?? labelled preS1(1-56) seems to be ∼15% of the total protein. to characterize the secondary structure of the labelled protein, circular dichroism was used. In different buffer conditions including pH 3.3 and pH 7.4 the protein seems to be devoid of any stable secondary structure probably suggesting that the N-terminal portion (preS1(1-56)) of HBV preS1 might be unstructured before binding to its target cells.
김시중,이영관,조원권 우송대학교 1996 우송대학교 논문집 Vol.1 No.-
Even though the tour business in Korea has grown rapidly with the changes of the time, it has caused lots of problems in the ethical aspects. Accordingly, the disagreements between tour business and society has been amplified and society requires new contract against tour business. By this reason. tour business is under an age of turning point that should solve comples ethical problems for themselves. To solve these ethical problems, sound business ethics must be established. To attain these goals, we should direct the study toward the basis of conceptual model of tour business. To do this, we have to seek after the ideology and spirits of business ethics developed by Yi Yi and Chung Yahk Yong who were representative scholar of Yi dynasty . We also have to set conceptual models in tour business ethics by adapting David Vogel's development model in business ethics, Joseph Badaracoo's business men's ethics model and David L. Whitney's determinant factors in tour business ethics. The conceptual model of tour business ethics represented by this study takes characteristic of basic research for the recognition of importance in tour business ethics and for the counter measure. By the consistent study, we must enhance tour business ethics and business image. we are going to ending up this study with the task of finding substantial alternatives that are essential to be an entrepreneur civilian internally and externally.
방향족 폴리에스터 폴리올을 이용한 폴리우레탄 분산체의 합성과 특성에 관한 연구
주훈관,조항규,노시태,강신춘,안재범 한국공업화학회 2004 응용화학 Vol.8 No.1
Aromatic polyurethane dispersions were synthesized with dimethylolpropionic acid (DMPA), isophorone diisocyanate(IPDI), and aromatic polyester polyol, prepared chemical reaction of esterification and polycondensation, The structures of these polyurethanes were characterized by FT0IR, H-NMR, and the properties were measured with DSC, TGA. Increase aromatic polyol contents made of unplasticized polyurethane dispersions. As the aromatic structures in polyurethane dispersions introduced, glass transition temperature(T_(g)) and thermal stability increased. In this polyurethane dispersions increased with DMPA concentrations, particle size decreased and dispersible stability increased and T_(g) increased over 50℃.
공기청정 겸용 전열교환 환기유니트 적용시 실내공기환경 CFD 시뮬레이션
이정재,이시환,김용경,박성관 대한건축학회 2005 대한건축학회논문집 Vol.21 No.3
Recently, indoor air pollution problem is happening in apartment housing due to the use of new building materials that emit poisonous chemical such as Volatile Organic Compounds (VOCs) and Formaldehyde (HCHO) etc. Therefore, the issues about security of healthy dwelling environment is becoming important. There are the methods to reduce indoor air contaminant. First, source control which is the method to control the emission of contaminant from building materials. Second, adopting the air cleaning and ventilation system which is the method to dilute the concentration of contaminant and exhaust the contaminant to outside of the building quickly. In this research, we evaluated the improvement effect of the indoor air quality quantitatively by using CFD(Computational Fluid Dynamics) simulation on the assumption that air cleaning and ventilation system is installed.
이지연,양시용,고은지,이승구,김시관,조왕식,송민동 建國大學校 自然科學硏究所 2002 建國自然科學硏究誌 Vol.13 No.2
본 연구가 VRSA에 대한 신규 항생물질 생산 균주를 얻기 위하여 실시하였다. 국내외에 채취한 토양시료에서 분리한 방선균 중, 임상분리 VRSA와 돌연변이 유발 VRSA에 대해 항균성을 나타내는 JY-24를 선별하였다. 선발 균주는 원통형의 포자 모양을 갖고 있으며, Bennett's 배지에 배양시 aerial mycelium color는 흰색을 나타냈으며, reverse side color는 대체로 노란색을 나타내었다. 항균물질 생산을 위한 탄소원으로는 fructose, mannose, 질소원으로는 yeast extract가 가장 우수하였으며 glucose의 첨가로 항균 물질 생산성이 증가하는 것으로 나타났다. 최적 초기 pH는 pH 7로 나타났으며, 28 ℃, 37℃, 45 ℃의 온도에서 균이 성장하는 것으로 나타났다. 또한 배양기간에 따라 항균물질 생산성을 조사한 결과, 임상분리 균주에 대해 5일 배양 시 가장 높았으나, 3일 배양과 7일 배양 시 동일한 생산성을 나타내 생산속도가 빠르며, 안정한 물질인 것이 파악되었다. 향후 균주동정 및 항균물질 정제에 관한 연구를 수행하고자 한다. An antibiotic substance producing strain JY-24, effective to the VRSA (Vancomycin-resistant Staphylococcus aureus), was isolated from soil. The spore chain of JY-24 was cylindrical, and its sulface was smooth. The aerial mass color of the strain was white, and its reverse side color was yellow. The strain did not produce soluble pigment. For the production antibiotics, fructose, mannose and yeast extract were favorable as carbon and nitrogen sources. Optimal initial pH for the production of the antibiotic was pH 7. Accumulation of the antibiotic in the culture broth reached at maximal level after 5 days cultivation in Bennett's medium.
이광태,김성호,송시헌,김관태,김윤 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.4
The authors report a case of false aneurysm of the superficial temporal artery which manifested after operation for FCCD. An aneurysm of the superficial temporal artery is a rare disease. In collected literature, the incidence of superficial temporal artery aneurysms ranged from 0.5 to 2.5 percent of all aneurysms for which surgery was performed. False aneurysm should be suspected when a mass, which may or may not be pulsatile, appears in the scalp region after recent trauma. Troublesome(but not life-threatening) bleeding may occur if the lesion is unrecognized, and an attempt is made to "shell it out" as though it were an epidermal inclusion cyst.
Trends in Ginseng Research in 2010
Si-Kwan Kim,Jeong Hill Park 고려인삼학회 2011 Journal of Ginseng Research Vol.35 No.4
A total of 470 papers directly related to research on the Panax species were retrieved by performing internet searches with the keywords Pan ax and ginseng as the search terms, The publications were categorized as follows: 399 research articles, 30 reviews, 30 meeting abstracts, 7 proceedings, and 4 letters. The majority of these publications were published by scientists from Korea (35.7%), China (32.3%), and the USA (J 1.3%). Scientists from a total of 29 nations were actively involved in conducting ginseng research. A total of 43.6% of the publications were categorized as pharmacodynamic studies. The effects of ginseng on cerebrovascular function and cancer were the two most common topics considered in the pharmacodynamic studies. More than half of the ginseng studies assessed the use of P ginseng. A total of23 countries participated in studies specifically related to P ginseng, and more than 80% of these studies originated from Korea and China. A total of 50 topics within the pharmacodynamics category were examined in association with the use of P ginseng.