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RISS 인기검색어
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- 저자 : Si-Seng (검색결과 6 건)
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The earliest timing of ultrasound in screening for developmental dysplasia of the hips
Si Heng Sharon Tan,Keng Lin Wong,Andrew Kean Seng Lim,James HoiPo Hui 대한초음파의학회 2019 ULTRASONOGRAPHY Vol.38 No.4
Purpose: The current study aimed to evaluate the results of ultrasound screening for developmental dysplasia of the hips (DDH) done at various weeks of life, to determine the earliest time that ultrasound screening can be performed reliably. Methods: In this 17-year cohort study, all neonates who underwent ultrasound screening prior to the 12th week of life with subsequent follow-up radiography done at 1 year of life were included. The ultrasound images were evaluated according to the Graf classification, Harcke’s dynamic ultrasound screening method, and Terjesen’s femoral head coverage method. The radiographic images were evaluated according to the acetabular index and the femoral head position. The accuracy and correlation between the ultrasound findings from various weeks of life with the radiographic findings at 1 year of life were evaluated. Results: A total of 348 neonates were included in the study, of whom 92 had abnormal ultrasound findings and 42 had abnormal radiographic findings at 1 year. Significant differences were identified between the findings of ultrasound screening examinations performed prior to the fourth week of life (day 21 and before) and the radiographic findings at 1 year of life (P<0.05). In contrast, no significant differences were identified when ultrasound screening was performed between the fourth and 12th weeks of life (day 22 and beyond) (P>0.05). The accuracy of ultrasound screening was 79.2% or higher when performed during or after the fourth week of life (day 22 and beyond). Conclusion: The earliest that ultrasound screening for DDH can be performed reliably is during the fourth week of life (day 22 and beyond).
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Inhibitory effect of 2,4-dichlorophenol on nitrogen removal in a sequencing batch reactor
Jun-Wei Lim,Si-Ling Ng,Siok-Moi Khor,Chye-Eng Seng 한국화학공학회 2012 Korean Journal of Chemical Engineering Vol.29 No.7
We examined the inhibitory effect of 2,4-dichlorophenol (2,4-DCP) on nitrogen removal in the sequencing batch reactor (SBR) system. The reactor was operated with FILL, REACT (nitrification: denitrification), SETTLE,DRAW and IDLE phases in the duration ratio of 2 : 12 (9 : 3) : 1 : 1 : 8 for a 24 h cycle time. The deterioration of 2,4-DCP removal efficiency from 100 to 41% was observed when the influent concentration of 2,4-DCP was increased to 30mg/L. The residual 2,4-DCP remaining in the mixed liquor was found to inhibit the nitrification process, resulting in the decrease of nitrogen removal efficiency to 25 %. For kinetic study, the result showed that the experimental data of ammoniacal nitrogen (AN) removal at every stage fitted well to the first-order kinetics equation with high R2 values. The rate constant of AN removal, kAN, decreased with increasing influent concentration of 2,4-DCP, from 0.053 to 0.0006/min when 2,4-DCP concentration increased from 0 to 30 mg/L, respectively. However, the observed gradual recovering of AN removal with respect to the removal efficiency and kinetics during the recovery stage indicated that the inhibitory effect of 2,4-DCP on the nitrification process was reversible.
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성정원,홍성문,김시완,김정아,박준철,김수현,서민정,허신회,김혜원,홍명호,최윤선,Seng, Jeong-Won,Hong, Sung-Moon,Kim, Si-Wan,Kim, Jeong-A,Park, Joon-Chul,Kim, Su-Hyun,Seo, Min-Jeong,Her, Sin-Hoe,Kim, Hye-Won,Hong, Myung-Ho,Choi, Youn-Seo 한국호스피스완화의료학회 2004 한국호스피스.완화의료학회지 Vol.7 No.1
배경: 호스피스 암 환자에게 적합한 경과기록지의 부재 또한 적절한 암성 통증 관리의 장애요인으로서 기존의 "문제 지향식 의무기록"의 경과기록지 형식에서 벗어나 호스피스 암 환자를 위한 의무기록지(HOMR)를 개발하게 되었다. 방법 및 결과: 2004년 3월부터 5월 사이 고대 구로병원 호스피스 팀은 20여 차례의 모임을 갖고 호스피스 환자의 초기 평가 이후 경과기록에 사용할 수 있는 의무기록지를 개발하였다. 구성항목의 결정은 pilot study를 통해 수정과정을 거쳤다. HOMR은 A4용지 크기로 작성자를 위한 지침서 1장과 2장의 경과기록지로 구성되었다. 앞면에는 환자의 인적 사항, 현재 문제목록 및 활동 수행 능력 상태, 검사 결과, 1주일 간의 활력 징후 및 I/O, 배변 횟수가, 뒷면에는 통증 부위, 통증의 성격 및 강도, 약물 및 비약물 요법, 진정 정도, 동반 증상, 약물 부작용 등을 한꺼번에 기록할 수 있도록 구성되어 있다. 결론: 호스피스 암 환자를 위한 의무기록지는 짧은 여명과 다양한 신체 증상을 갖고 있으며 증상의 변화가 빠르지만 만성적인 경과를 보이는 호스피스 환자에게 적합하며 그 자체만으로도 교육자료로서의 가치가 높고 환자를 돌보는 데 있어 진료의 질을 평가하거나 심사할 수 있으므로 진료의 질을 높이는 역할도 기대된다. Purpose: The Hospice Oriented Medical Record (HOMR) was developed for assessing the pain and symptoms of terminal cancer patients. Methods and Results: The HOMR consists of an instruction for users and 2 assessment pages which include the graph showing vital signs (temperature, blood pressure, pulse, respiration rate and pain score), current problem lists, performance status, laboratory data, pain characteristics and management, sedation score, associated symptoms and drug side effects, etc. Pilot study was performed in the inpatient Hospice Care Unit in Guro Hospital, Korea University Medical Center. Because an one-week progress data was recorded in HOMR as a flow sheet, the patient's condition and pain control status could be seen at a glance. Conclusion: The HOMR is useful for assessing the terminal cancer patients because it is simple and convenient to use. Further research is needed before it can be universally used in the clinical settings.
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( Soon Kyu Lee ),( Pil Soo Sung ),( Jeong Won Jang ),( Si Hyun Bae ),( Jong Young Choi ),( Seng Kew Yoon ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: In the treatment of hepatocellular carcinoma (HCC), single very large carcinoma (≥7cm) is still difficult for clinician to choose treatment modality due to concern of recurrence. In this study, we aimed to evaluate the survival across treatment modalities in single large carcinoma without portal vein throm bosis (PVT). Methods: From 2002 to 2013, 1,685 patients were newly diag nosed HCC patients in Seoul St. Mary’s hospital. Of them, 1,628 patients were excluded with following reasons: metastasis (187 patients), less than 7cm (1,095 patients), PVT (249 patients) and multiple HCC (93 patients). 57 patients were included and evaluated on overall survival according to treatment mortalities. Moreover, response rate using RECIST 1.1, recurrence free sur vival and risk factor for survival were also examined Results: Fifty-seven included patients had mean 59.7 years and hepatitis B (50.9%) was the main etiology. The majority were CTP class A (86.0%) and 18 patients had cirrhosis. The median tumor size and AFP were 10.0cm (7.0-14.9cm), 70.6ng/mL (0.7-200,000), respectively. There were no significant differ ence in baseline characteristics between treatment modalities. Surgery based group (n=11) had higher survival than other treatment group (P=0.008). In subgroup analysis, surgery based group showed higher survival than TACE only group (n=21), TACE based group (n=6) and conservative group (n=4). How ever, compared with TARE based group (n=5), there was no significant difference. Better response (complete response [CR] rate: 91%) was note in surgery based group than that of TACE only group (CR rate: 41%) and TACE based group (CR rate: 19%). Surgery based group had better recurrence free survival than other treatment group without significance (P=0.062). In multivariate analysis, surgery based treatment (P=0.027), creat inine (P=0.016) and AFP (P=0.004) were independent prognos tic factors for survival. Conclusions: In the treatment of single large (≥7cm) HCC without PVT, surgery based treatment was better treatment modality than other treatments.
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