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      • KCI등재

        Recent advances in valorization of citrus fruits processing waste: a way forward towards environmental sustainability

        Shweta Suri,Anupama Singh,Prabhat K. Nema 한국식품과학회 2021 Food Science and Biotechnology Vol.30 No.13

        Citrus fruits are well known for their medicinaland therapeutic potential due to the presence of immensebioactive components. With the enormous consumption ofcitrus juice, citrus processing industries are focused on theproduction of juice but at the same time, a large amount ofwaste is produced mainly in the form of peel, seeds,pomace, and wastewater. This waste left after processingleads to environmental pollution and health-related hazards. However, it could be exploited for the recovery ofessential oils, pectin, nutraceuticals, macro and micronutrients,ethanol, and biofuel generation. In view of theimportance and health benefits of bioactive compoundsfound in citrus waste, the present review summarizes therecent work done on the citrus fruit waste valorization forrecovery of value-added compounds leading to zerowastage. Therefore, instead of calling it waste, these couldbe a good resource of significant valuable components, inthis way encouraging the zero-waste theory.

      • KCI등재

        APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions

        Shweta Thakur,Bibekananda Sarkar,Ravi P Cholia,Nandini Gautam,Monisha Dhiman,Anil K Mantha 생화학분자생물학회 2014 Experimental and molecular medicine Vol.46 No.-

        Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme involved in the base excision repair (BER) pathway, which repairs oxidative base damage caused by endogenous and exogenous agents. APE1 acts as a reductive activator of many transcription factors (TFs) and has also been named redox effector factor 1, Ref-1. For example, APE1 activates activator protein-1, nuclear factor kappa B, hypoxia-inducible factor 1a, paired box gene 8, signal transducer activator of transcription 3and p53, which are involved in apoptosis, inflammation, angiogenesis and survival pathways. APE1/Ref-1 maintains cellular homeostasis (redox) via the activation of TFs that regulate various physiological processes and that crosstalk with redox balancing agents (for example, thioredoxin, catalase and superoxide dismutase) by controlling levels of reactive oxygen and nitrogen species. The efficiency of APE1/Ref-1’s function(s) depends on pairwise interaction with participant protein(s), the functions regulated by APE1/Ref-1 include the BER pathway, TFs, energy metabolism, cytoskeletal elements and stressdependent responses. Thus, APE1/Ref-1 acts as a ‘hub-protein’ that controls pathways that are important for cell survival. In this review, we will discuss APE1/Ref-1’s versatile nature in various human etiologies, including neurodegeneration, cancer, cardiovascular and other diseases that have been linked with alterations in the expression, subcellular localization and activities of APE/Ref-1. APE1/Ref-1 can be targeted for therapeutic intervention using natural plant products that modulate the expression and functions of APE1/Ref-1. In addition, studies focusing on translational applications based on APE1/Ref-1-mediated therapeutic interventions are discussed.

      • KCI등재

        Study of microstructure, impedance and dc electrical properties of RuO2-spinel based screen printed ‘green’ NTC thermistor

        Shweta Jagtap,Sunit Rane,Rohini Aiyer,Suresh Gosavi,Dinesh Amalnerkar 한국물리학회 2010 Current Applied Physics Vol.10 No.4

        The NTC powder materials were prepared chemically using acetates of (Mn–Co–Ni), as precursor materials. The sintering of the powders shows the existence of spinel phases at comparatively low temperature,i.e. 800 ℃. ‘Green’ thick films were prepared by admixing of the spinel powder, RuO2, lead free glass frit and the organic vehicle. Synthesized powders as well as the thermistor films were characterised by FTIR spectroscopy, TG/DTA, XRD and SEM. The electrical parameters like sheet resistance, thermistor constant,temperature co-efficient of resistance of the thick film thermistors are presented. The impedance of the thermistor films was measured and it has been correlated with the theoretical model and its equivalent circuit using the ‘Cole–Cole’ plots.

      • KCI등재

        해양생물 체내 잔류 미세플라스틱 조사

        Shweta Borkar,Sondavid Nandanwar,김영일,김돈,심현관,김학준 한국수산과학회 2020 한국수산과학회지 Vol.53 No.2

        Microplastic pollution in the marine ecosystem has been emerged as a global issue. In this study, we investigated theabundance of microplastics from clam Meretrix lusoria, blood arkshell Scapharca broughtonii, and warty sea squirtStyela clava obtained from a local market in Busan, Korea. The marine organisms were digested in 10% KOH, andwere incubated at 40˚C and 150 rpm, for 7 days. The digest was filtered through standard sieve (5 mm, 1 mm, 300μm, and 100 μm), and mciroplastics were identified using a light microscope and microFT-IR. The abundance ofmicroplastics of clam, blood arkshell, warty sea squirt was 0.08 items/g, 0.05 items/g, and 0.12 items/g, respectively. The predominant microplastic size was in the range of 100-300 μm, occupying 48%, and the predominant type wasfiber. The composition of microplastics was mostly rayon, semi-synthetic cellulosic material and polyester, which aremain component of fabric and textile. We strongly believe that this preliminary work may provide useful informationfor the establishment of the standardized analysis method of microplastics ingested by marine organisms.

      • KCI등재

        A Two-Dimensional (2D) Analytical Model for the Potential Distribution and Threshold Voltage of Short-Channel Ion-Implanted GaAs MESFETs under Dark and Illuminated Conditions

        Shweta Tripathi,S. Jit 대한전자공학회 2011 Journal of semiconductor technology and science Vol.11 No.1

        A two-dimensional (2D) analytical model for the potential distribution and threshold voltage of short-channel ion-implanted GaAs MESFETs operating in the sub-threshold regime has been presented. A double-integrable Gaussian-like function has been assumed as the doping distribution profile in the vertical direction of the channel. The Schottky gate has been assumed to be semi-transparent through which optical radiation is coupled into the device. The 2D potential distribution in the channel of the shortchannel device has been obtained by solving the 2D Poisson’s equation by using suitable boundary conditions. The effects of excess carrier generation due to the incident optical radiation in channel region have been included in the Poisson’s equation to study the optical effects on the device. The potential function has been utilized to model the threshold voltage of the device under dark and illuminated conditions. The proposed model has been verified by comparing the theoretically predicted results with simulated data obtained by using the commercially available ATLAS™ 2D device simulator.

      • KCI등재후보

        Red Upconversion Luminescence and Paramagnetism in Er/Yb Doped SnO2

        Shweta Sharma,Jyoti Shah,R.K. Kotnala,Santa Chawla 대한금속·재료학회 2013 ELECTRONIC MATERIALS LETTERS Vol.9 No.5

        Red upconversion luminescence has been introduced in functional semiconductor SnO2 by doping rare earth ions Er3+ and Yb3+ and using 980 nm diode laser as pump source. High temperature solid state reaction leads to incorporation of trivalent lanthanide ions in SnO2. For high concentrations of lanthanide doping,partial reduction of Sn4+ to Sn2+ occurs for charge compensation making the material system SnO2-SnO alloy. Upconverting SnO2 exhibits paramagnetic characteristics with magnetization increasing with introduction of trivalent rare earth ions Er3+/Yb3+.

      • KCI등재후보

        Somatic embryogenesis from the axillary meristems of peanut (Arachis hypogaea L.)

        Shweta Singh,Sulekha Hazra 한국식물생명공학회 2009 Plant biotechnology reports Vol.3 No.4

        Developmental anomalies in the plumule meristem of peanut (Arachis hypogaea L.) somatic embryos resulted in poor shoot differentiation and reduced plant recovery. Existing meristems with caulogenic potential have never been tested for embryogenesis in peanut. The present experiment was designed to test the mature zygotic embryo axis derived plumule with three meristems for somatic embryogenesis. Embryogenic masses and embryos developed from the caulogenic meristems in the axils. Exposure of 2 weeks in primary medium with 90.5 lM 2,4-D suppressed the shoot tip differentiation temporarily which then regained the ability to form the shoot on withdrawal of 2,4-D. Exposure of 4 weeks in primary medium with 90.5 lM 2,4-D suppressed the shoot tip differentiation irreversibly. No shoot formation was noted from the tips in any of the cultures which were in secondary medium with 13.6 lM 2,4-D. Development of somatic embryos directly from axillary meristems was confirmed histologically. Conversion frequency of these embryos was 11%. Thus, in this report, we describe a method to obtain somatic embryos from the determined organogenic buds of the axillary meristem, by culturing the nodal explant vertically on embryo induction medium. It also displays the possibility of obtaining both embryogenic and organogenic potential in two parts of the same explant simultaneously. The possibility of extending this approach for genetic transformation in in vivo system through direct DNA delivery or Agrobacterium injection in meristems can also be explored. Using Agrobacterium rhizogenes, we have demonstrated the possibility of gene transfer in the axillary meristems of seed-derived plumule explant. Developmental anomalies in the plumule meristem of peanut (Arachis hypogaea L.) somatic embryos resulted in poor shoot differentiation and reduced plant recovery. Existing meristems with caulogenic potential have never been tested for embryogenesis in peanut. The present experiment was designed to test the mature zygotic embryo axis derived plumule with three meristems for somatic embryogenesis. Embryogenic masses and embryos developed from the caulogenic meristems in the axils. Exposure of 2 weeks in primary medium with 90.5 lM 2,4-D suppressed the shoot tip differentiation temporarily which then regained the ability to form the shoot on withdrawal of 2,4-D. Exposure of 4 weeks in primary medium with 90.5 lM 2,4-D suppressed the shoot tip differentiation irreversibly. No shoot formation was noted from the tips in any of the cultures which were in secondary medium with 13.6 lM 2,4-D. Development of somatic embryos directly from axillary meristems was confirmed histologically. Conversion frequency of these embryos was 11%. Thus, in this report, we describe a method to obtain somatic embryos from the determined organogenic buds of the axillary meristem, by culturing the nodal explant vertically on embryo induction medium. It also displays the possibility of obtaining both embryogenic and organogenic potential in two parts of the same explant simultaneously. The possibility of extending this approach for genetic transformation in in vivo system through direct DNA delivery or Agrobacterium injection in meristems can also be explored. Using Agrobacterium rhizogenes, we have demonstrated the possibility of gene transfer in the axillary meristems of seed-derived plumule explant.

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