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      • Is Ethical Counseling Possible: A Virtue Ethics Approach to Philosophical Counseling?

        Shu‐Ju Yu 강원대학교 인문과학연구소 2010 Journal of Humanities Therapy Vol.1 No.-

        Is ethical counseling possible? This paper attempts to demonstrate that the possibility of ethical counseling. The second intention is to inquire into the basic appearance of virtue ethics approach to ethical counseling by Alasdair MacIntyre’s virtue ethics. In the foreword section, I surveyed ethics and morals in the view of conventional psychotherapy and psychotherapy in Taiwan. For the existence of ethical suffering from the multiple realities of a suffering experience, it is indicated that suffering not only exists, it is at the core of Chinese suffering. From the current development of ethical therapy in psychotherapy, that could explain the feasibility and necessity of ethical counseling. In the second section, I try to analyze the points of ethical counseling, especially in situation and relationship. Ethical suffering serves as the focus of counseling and its contents include: agents, relationships and situations. An individual in suffering, it is usually in an ethical or moral situation. The cause of ethical suffering is a certain cut off or conflict in the relationship between a sort of external form of ethical humanity and pondering space in individual morality. In the Third, to enter the main part of this paper, I attempts to search for experiences from ethical therapy that can be applied to ethical counseling and then try to study the contents of ethical counseling from the essence of philosophical counseling. To do this, the paper first gives a brief description of Alasdair MacIntyre’s thinking on virtue ethics and then the correlation between virtue ethics and ethical practices. Fourth, construction of ethical counseling is attempted based on Alasdair MacIntyre’s virtue ethics. This section is studied from the standpoint of ethical diagnosis and therapy models.

      • 맥주맥 F_1세대의 조합능력 검정

        정원복,오주성,황필성,김수동,서세정,현종내,김대호 東亞大學校 2002 東亞論叢 Vol.39 No.-

        맥주맥의 이면교잡에 의한 F_1세대에 대한 조합능력을 검정한 결과를 요약하면 다음과 같다. 8개 형질에 대한 GCA, SCA, RCA효과를 검정한 바 조합능력은 전 형질에서 GCA, SCA, RCA가 모두 유의하였는데 간장, 수장, 망장, 간직경, 곡핍폭, 1수립수 1000립중은 GCA가 SCA보다 크고, 품종간 GCA효과는 진양보리가 간장에서 부(-)이고, 삼도보리가 수장·망장·간직경·1000립중에서, 사천6호가 망장과 간직경에서, 진광보리가 곡립장에서, 두산29호가 곡립폭·1수립수·1000립중에서 각각 정(+)으로 높았다. SCA효과에서 수장은 두산29호×두산8호 조합이, 망장은 진양보리×두산29호 조합이, 간직경은 사천6호×진광보리 조합이, 곡립장은 진양보리×두산8호 조합이, 곡립폭은 진광보리×두산8호 조합이, 1수립수는 진양보리×삼도보리 조합이, 1000립중은 사천6호×두산8호 조합 및 두산29호×두산8호 조합이 각각 정으로 높았고, 간장은 삼도보리×진광보리 조합이 부로서 높았다. RCA효과에서 수장은 두산8호×남향보리 조합이, 망장은 진양보리×삼도보리 조합이, 간직겨은 사천6호×진양보리 조합이, 곡립장은 사천6호×진광보리 조합이, 곡립폭은 진양보리×삼도보리 조합이, 1수립수는 사천6호×두산29호 조합이, 1000립중은 진양보리×두산29호 조합이 각각 정으로 높았고, 간장은 사천6호×두산29호 조합이 부로서 높았다. Seven barley varieties in F_1 generation of the possible crosses among them were used to estimate the combining ability for eight characters, i.e., culm length, spike length, awn length, culm diameter, grain length, grain width, number of grains per spike and 1000 grains weight. Data for F_1 hybrid and parents were subjected to the analysis method proposed by Griffing. The results obtained were summarized as follows. mean squares of general combining ability(GCA), specific combining ability(SCA) and reciprocal combining ability(RCA) were significant for all characters observed. Mean squares of GCA were higher than those of SCA and RCA in culm length, spike length, awn length, culm diameter, grain width, number of grains per spike and 1000 grains weight. Variety Dusan#29 showed the highest GCA effect for number of grains per spike and positively high effects of GCA were observed from variety Samdo bori in spike length, awn length, culm diameter, 1000 grains weight, and from variety Jinkwang bori I grain length, from Dusan#29 in grain width, umber of grains per spike, 1000 grains weight. Also Jinyang bori showed negatively high GCA effect in culm length. In SCA effects, hybrids in Jinyang bori × Samdo bori were exhibited positively high for number of grains per spike and high SCA effects for 1000 grins weight were found positively in Sacheun#6×Dusan#8 and Dusan#29×Dusan#. In RCA effects, hybrids in Sacheun#6×Dusan#29 were exhibited positively high for number of grains per spike and high RCA effects for 1000 grains weight were found positively in Jinyang bori×Dusan#29.

      • KCI등재

        Osthole Attenuates Inflammatory Responses and Regulates the Expression of Inflammatory Mediators in HepG2 Cells Grown in Differentiated Medium from 3T3-L1 Preadipocytes

        Shu-Ju Wu 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.9

        This study explored the anti-inflammatory mechanisms by which osthole acted on HepG2 cells cultured in a differentiated medium from cultured 3T3-L1 preadipocyte cells. HepG2 cells, a human liver cell line, were treated with various concentrations of osthole in differentiated media from cultured 3T3-L1 cells to evaluate proinflammatory cytokines, inflammatory mediators, and signaling pathways. We used enzyme-linked immunosorbent assay kits to determine the levels of proinflammatory cytokines, real-time polymerase chain reaction to assay the mRNA expression, and western blot to determine the expression of cyclooxygenase-2 (COX-2) and heme oxygenase-1 (HO-1) proteins. We also investigated inflammatory mechanism pathway members, including mitogen-activated protein kinase (MAPK) and nuclear transcription factor kappa-B (NF-κB). Osthole was able to suppress the levels of proinflammatory cytokines interleukin (IL)-1β and IL-6, as well as chemokines monocyte chemoattractant protein-1 and IL-8. In addition, COX-2 was suppressed and HO-1 expression was increased in a concentration-dependent manner. Osthole was also able to decrease IκB-α phosphorylation and suppress the phosphorylation of MAPKs. These results suggest that osthole has anti-inflammatory effects as demonstrated by the decreased proinflammatory cytokine and mediator production through suppression of the NF-κB and MAPK signaling pathways in HepG2 cells when they are incubated on the differentiated medium from 3T3-L1 cells.

      • KCI등재

        Curcumin or Saikosaponin a Improves Hepatic Antioxidant Capacity and Protects Against CCl4-Induced Liver Injury in Rats

        Shu-Ju Wu,Yun-Ho Lin,Chia-Chou Chu,Ya-Hui Tsai,Jane C.-J. Chao 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.2

        Curcumin and saikosaponin a, the bioactive phytochemicals of turmeric and Bupleurum, act as antioxidants.This study investigated the effects of supplementation with curcumin and/or saikosaponin a on hepatic lipids and antioxidantstatus in rats with CCl4-induced liver injury. Male Sprague-Dawley rats were randomly divided into control, CCl4, CCl4 .curcumin (0.005%; CU), CCl4 . saikosaponin a (0.004%; SS), and CCl4 . curcumin. saikosaponin a (0.005%. 0.004%;CU. SS) groups. CCl4 (40% in olive oil) was injected intraperitoneally at a dose of 0.75 mL/kg once a week. Curcumin and/orsaikosaponin a was administered orally 1 week before CCl4 injection for 8 weeks. The pathological results showed that liverfibrosis was ameliorated in the SS and CU. SS groups. After 8 weeks, supplementation with curcumin and/or saikosaponina significantly decreased plasma alanine aminotransferase and aspartate aminotransferase activities, as well as plasma and he-patic cholesterol and triglyceride levels. The CU. SS group showed reversal of the impaired hepatic superoxide dismutaseactivity and an increase in total glutathione level. Supplementation with curcumin and/or saikosaponin a significantly im-proved hepatic antioxidant status and suppressed malondialdehyde formation. Therefore, supplementation with curcumin and/orsaikosaponin a protects against CCl4-induced liver injury by attenuating hepatic lipids and lipid peroxidation and enhancingantioxidant defense. Curcumin and saikosaponin a had no additive effects on hepatoprotection except for greater improve-ment in the total glutathione level and antioxidant status.

      • KCI등재

        네일 고객 손의 특징과 계절에 따른 네일 컬러와 아트기법의 선호도 연구 분석

        편수명(Shu-Myung Pyun),한선주(Sun-Ju Han) 한국인체미용예술학회 2011 한국인체미용예술학회지 Vol.12 No.2

        The present study aims to explain if there are differences between seasonal image colors and nail art color preferences, if there are colors suited for the characteristics of hands, and if nail art techniques differ depending on the season. The survey was conducted on clients living in Gwangju with the age ranging from their 10s to 40s focusing on the client characteristics and preferences of nail art colors and techniques in accordance with their physical traits (hand shape and skin color). The first-round survey consisted of seven questions about personal characteristics, and the second-round interview consisted of 11 questions about the preferences of nail art colors and techniques. As a result, the preferred colors in spring were white, red and purple. The nail colors preferred in summer were orange, white, and green as well as bluish green. The nail colors preferred in winter are purple, bluish green, and navy blue. As for nail art techniques, one-color, two-tone, and gradation techniques were most preferred throughout four seasons, and air brush technique was also highly preferred.

      • KCI등재

        Antiviral activity of Rheum palmatum methanol extract and chrysophanol against Japanese encephalitis virus

        Shu-Jen Chang,Su-Hua Huang,Ying-Ju Lin,Yi-Yun Tsou,Cheng-Wen Lin 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.9

        Rheum palmatum, Chinese traditional herb,exhibits a great variety of anti-cancer and anti-virusesproperties. This study rates antiviral activity of R. palmatumextracts and its components against Japanese encephalitisvirus (JEV) in vitro. Methanol extract of R. palmatumcontained higher levels of aloe emodin, chrysophanol, rhein,emodin and physcion than water extract. Methanol extract(IC50 = 15.04 lg/ml) exhibited more potent inhibitoryeffects on JEV plaque reduction than water extract(IC50 = 51.41 lg/ml). Meanwhile, IC50 values determinedby plaque reduction assay were 15.82 lg/ml for chrysophanoland 17.39 lg/ml for aloe-emodin, respectively. Virucidalactivity of agents correlated with anti-JEV activity,while virucidal IC50 values were 7.58 lg/ml for methanolextract, 17.36 lg/ml for water extract, 0.75 lg/ml forchrysophanol and 0.46 lg/ml for aloe-emodin, respectively. In addition, 10 lg/ml of extract, chrysophanol or aloeemodin caused 90 % inhibition of JEV yields in cells andsignificantly activated gamma activated sequence-drivenpromoters. Hence, methanol extract of R. palmatum andchrysophanol with high therapeutic index might be usefulfor development of antiviral agents against JEV.

      • KCI등재

        The white gene in Nilaparvata lugens and its expression pattern under two different survival stresses

        Shu Hua Liu,Bao Jun Yang,Ai YingWang,Ju Luo,Jian Tang 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.2

        The brown planthopper (BPH), Nilaparvata lugens (Stål), is a serious pest of rice. Chemical control and pestresistant rice breeding are always two major management strategies of BPH. In order to keep effective control, understanding the detoxification mechanism of this insect pest appears to be high important. In addition to be an eye pigment transporter, White protein is also important for its non-eye roles, such as a potential target for insecticides and Bt toxin. In this study, we characterized the full-length white orthologues gene in N. lugens (Nlwhite). NlWhite, the deduced protein of Nlwhite, has feature motifs of the eye pigment transporter. Knocking down Nlwhite transcript, the compound eye color partially changed to white. Nlwhite can be detected in all developmental stages and body parts, indicating that it is not a developmental or tissue-specific expression gene. The expression levels of Nlwhite were all significantly upregulated in both pymetrozine-selection and Mudgoselection BPH strains, which were selected for several generations. These results indicated that NlWhite participated in the detoxification not only for the exogenous insecticides but also for the endogenous toxic substance.

      • KCI등재

        Fatty Acid Binding Protein 5 (FABP5) Promotes Aggressiveness of Gastric Cancer Through Modulation of Tumor Immunity

        Shu Zhang,Mei-qing Qiu,Hui-jun Wang,Ya-fei Ju,Zhen Liu,Tao Wang,Shi-feng Kan,Zhen Yang,Ya-yun Cui,You-qiang Ke,Hong-min He,Li Sun 대한위암학회 2023 Journal of gastric cancer Vol.23 No.2

        Purpose: Gastric cancer (GC) is the second most lethal cancer globally and is associated with poor prognosis. Fatty acid-binding proteins (FABPs) can regulate biological properties of carcinoma cells. FABP5 is overexpressed in many types of cancers; however, the role and mechanisms of action of FABP5 in GC remain unclear. In this study, we aimed to evaluate the clinical and biological functions of FABP5 in GC. Materials and Methods: We assessed FABP5 expression using immunohistochemical analysis in 79 patients with GC and evaluated its biological functions following in vitro and in vivo ectopic expression. FABP5 targets relevant to GC progression were determined using RNA sequencing (RNA-seq). Results: Elevated FABP5 expression was closely associated with poor outcomes, and ectopic expression of FABP5 promoted proliferation, invasion, migration, and carcinogenicity of GC cells, thus suggesting its potential tumor-promoting role in GC. Additionally, RNA-seq analysis indicated that FABP5 activates immune-related pathways, including cytokine-cytokine receptor interaction pathways, interleukin-17 signaling, and tumor necrosis factor signaling, suggesting an important rationale for the possible development of therapies that combine FABP5-targeted drugs with immunotherapeutics. Conclusions: These findings highlight the biological mechanisms and clinical implications of FABP5 in GC and suggest its potential as an adverse prognostic factor and/or therapeutic target.

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