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      • KCI등재

        Overview of Computer Simulation on Laser Fusion in China

        shao-ping Zhu,W. Y. Zhang 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III

        Laser fusion research in China is organized by the National High-Tech Inertial Confinement Fusion Committee. Computer simulation is one of the most important research fields supported by the Committee. In the last decade, much effort has been made to develop the computer simulation code series named LARED. In recent years, a number of numerical simulations using LARED have been carried out and the simulation is checked by experiments done at the laser facility SG-II. In the present paper, we introduce the basic physics models used in LARED, the code structures, and some simulation results given by the code series.

      • Surgical Treatment for Early Esophageal Squamous Cell Carcinoma

        Chen, Shao-Bin,Weng, Hong-Rui,Wang, Geng,Yang, Jie-Sheng,Yang, Wei-Ping,Liu, Di-Tian,Chen, Yu-Ping,Zhang, Hao Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

        More studies are needed to clarify treatments and prognosis of early esophageal squamous cell carcinoma (ESCC). This retrospective study was designed to review the outcome of surgical treatment for early ESCC, evaluate the results of a left thoracotomy for selected patients with early ESCC, and identify factors affecting lymph node metastases and survival. The clinicopathological data of 228 patients with early ESCC who underwent transthoracic esophagectomy with lymphadenectomy without preoperative adjuvant treatment were reviewed. The ${\chi}^2$ test or Fisher's exact test were used to detect factors related to lymph node metastasis. Univariate and multivariate analyses were performed to identify prognostic factors. There were 152 males and 76 females with a median age of 55 years. Two hundred and eight patients underwent a left thoracotomy, and the remaining 20 patients with lymph nodes in the upper mediastinum more than 5 mm in short-axis diameter by computed tomography scan underwent a right thoracotomy. No lymph node metastasis was found in the 18 patients with carcinoma in situ, while lymph node metastases were detected in 1.6% (1/62) of patients with mucosal tumours and 18.2% (27/148) of patients with submucosal tumours. Only 7 patients showed upper mediastinal lymph node metastases in the follow-up. The 5- and 10-year overall survival rates were 81.4% and 70.1%, respectively. Only histologic grade (P<0.001) and pT category (P=0.001) significantly correlated with the presence of lymph node metastases. In multivariate analysis, only histologic grade (P=0.026) and pT category (P=0.008) were independent prognostic factors. A left thoracotomy is acceptable for selected patients with early ESCC. Histologic grade and pT category affected the presence of lymph node metastases and were independent prognostic factors for early ESCC.

      • Phase II Clinical Study on the GEMOX Regimen as Second-line Therapy for Advanced Ovarian Cancer

        Yuan, Shao-Fei,Zhang, Lian-Ping,Zhu, Lin-Jia,Chen, Wen-Jun,Zheng, Wei-E,Xiong, Jian-Ping Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

        Aim: To investigate the effectiveness and adverse effects of gemcitabine by fixed-dose rate infusion plus oxaliplatin (GEMOX regimen) as second-line therapy for advanced ovarian cancer. Methods: 64 patients with advanced ovarian cancer were divided into an experimental group (44 cases) and a control group (20 cases). The experimental group was treated with continuous intravenous infusion of gemcitabine at 1000 $mg/m^2$ with a fixed-dose rate of 10 $mg/m^2/min$, on days 1 and 8 and oxaliplatin at 100 $mg/m^2$ on day 1, IVGTT, repeated every 3 weeks. The control group was treated with intravenous infusion of gemcitabine at 1000 $mg/m^2$ within 30 min on days 1 and and oxaliplatin at 100 $mg/m^2$ on day 1, IVGTT, again repeated every 3 weeks. CT scans or MRI were used for review every 1-2 cycles. Results: The effective rate in the experimental group was significantly high than control group (43.2% vs 35.0%; P < 0.05), with no obvious difference of hematologic or non-hematologic toxicity between the two groups (P > 0.05). Conclusion: GEMOX regimen is very effective to treat advanced ovarian cancer, with low toxicity, good tolerance and improved life quality in patients.

      • KCI등재

        특집. 동아시아 문학 속 상인형상 : 상인과 여인 그리고 선비 -중국 전통시기의 문학작품에 등장하는 상인을 예로 들어-

        소의평 ( Yi Ping Shao ) 고려대학교 민족문화연구원 2015 民族文化硏究 Vol.68 No.-

        The triangle relationship among businessman, woman and literati is often represented in classical Chinese literature. The representation is modeled on the failure of businessmen in winning women’s heart in competition with the literati, whose literary talents are often adored by the female with bias against the wealth of businessmen. In fact, this triangle relationship is imagined by the literati in compensation for their defeat by businessmen in real life. In literary imagination, the literati gain the upper hand over businessmen and retaliate upon them whom they can hardly overpower in reality. From Tang poetry to Yuan drama, to Ming novels in vernacular, and to Qing novels in classical Chinese, literati’s literary imagination turns from hidden to overt, and gradually exhibits realistic and even comical features. This thesis gives a detailed description and analysis of the evolution of the everlasting imagination of the literati.

      • Knockdown of GCF2/LRRFIP1 by RNAi Causes Cell Growth Inhibition and Increased Apoptosis in Human Hepatoma HepG2 Cells

        Li, Jing-Ping,Cao, Nai-Xia,Jiang, Ri-Ting,He, Shao-Jian,Huang, Tian-Ming,Wu, Bo,Chen, De-Feng,Ma, Ping,Chen, Li,Zhou, Su-Fang,Xie, Xiao-Xun,Luo, Guo-Rong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

        Background: GC-binding factor 2 (GCF2) is a transcriptional regulator that represses transcriptional activity of the epidermal growth factor receptor (EGFR) by binding to a specific GC-rich sequence in the EGFR gene promoter. In addition to this function, GCF2 has also been identified as a tumor-associated antigen and regarded as a potentially valuable serum biomarker for early human hepatocellular carcinoma (HCC) diagnosis. GCF2 is high expressed in most HCC tissues and cell lines including HepG2. This study focused on the influence of GCF2 on cell proliferation and apoptosis in HepG2 cells. Materials and Methods: GCF2 expression at both mRNA and protein levels in HepG2 cells was detected with reverse transcription (RT) PCR and Western blotting, respectively. RNA interference (RNAi) technology was used to knock down GCF2 mRNA and protein expression. Afterwards, cell viability was analyzed with a Cell Counting Kit-8 (CCK-8), and cell apoptosis and caspase 3 activity by flow cytometry and with a Caspase 3 Activity Kit, respectively. Results: Specific down-regulation of GCF2 expression caused cell growth inhibition, and increased apoptosis and caspase 3 activity in HepG2 cells. Conclusions: These primary results suggest that GCF2 may influence cell proliferation and apoptosis in HepG2 cells, and also provides a molecular basis for further investigation into the possible mechanism at proliferation and apoptosis in HCC.

      • KCI등재

        中日韓外語敎育政策的比較硏究

        소염평 ( Yan Ping Shao ) 전남대학교 인문학연구소 2014 용봉인문논총 Vol.- No.44

        신세기 들어서 글로벌 경제 통합 발전에 순응하기 위해 한·중·일 3국은 전략적인 차원에 착안해 적극적으로 외국어 교육을 국제화 되는것에 진력하고 있다. 이 논문에서 한·중·일 3개 국의 외국어 교육 정책을 비교하고 분석한 결론으로 구체적인 교육에 관한 기획과 조치가 똑같지는 않지만 공통적인 내용이 적지 않다. 구체적으로 한·중·일 3국 외국어 교육 정책의 공통점은 주로 다음과 같이 4가지를 총괄할수 있다. 첫째, 한·중·일 3국은 모두 본국의 외국어 교육 이념과 학교경영 환경의 국제화를 최대한으로 추진하여 해외와의 교육 협력을 도모하고 유학 규모를 확대하는 것이다. 둘째, 한·중·일 3국은 모두 적극적으로 영어 교육을 개혁하고 전통적인 입시 위주의 교육에서 소양교육으로 전변하는 것을 지향함으로 영어로 강의를 하는 과정의 비율을 증가시기고 있는 것이다. 셋째, 한·중·일 3국은 제2외국어 교육을 전반적인 수준을 인상시키기 위해 제2외국어로 학교와 사회 외국어 교육에 지연적으로 우위가 있는 중국어, 한국어, 등의 보급도가 갈수록 높이고 있다. 넷째, 한·중·일 3국은 외국어 교육을 발전하는 동시에 모국어에 대한 보호와 수출을 강화함으로써 본국의 문화 소프트파워를 향상시키고 있다. In order to conform to the trend of global economic integration, China, Japan and Korea all actively adjust their foreign language education policy on a strategic height to the internationalization of foreign language education since the new century. This article compares and analyzes the three countries’ foreign language policy, although specific plans and measures are different, they have some distinctive in common. These distinctive can be summarized specifically as follows: First, the three countries have vigorously promoted the internationalization of their foreign language educational ideas and teaching environments, facilitated the educational cooperation with overseas countries and expanded the scale of studying abroad. Second, they all have actively reformed English education, advocated the transformation from examination-oriented education toward quality education and raised the percentage of teaching in English. Next, they have comprehensively enhanced second language education, as a result, especially Chinese, Japanese and Korean gained their popularity in both school and social foreign language education by relying on geographical advantages. Finally, the three countries have strengthened the protection and output of the mother tongue and thus enhance their national cultural soft power as well as develop foreign language education at the same time.

      • KCI등재

        《 두붕한화 》 : 중국고전소설중적광가결구

        소의평(Yi Ping Shao) 영남중국어문학회 1997 중국어문학 Vol.30 No.1

        세계문학사상 $quot;액자구조$quot;는 이전에 비교적 흔히 볼 수 있던 서술구조이다. 이 $quot;액자구조$quot;의 유래는 고인도에서 시작되며, 작품으로는 ≪Pa¨ncatatra≫ 등이 있다. 이것이 이후에 페르시아에 전래되어 ≪천일야화≫가 나왔으며, 그 뒤에 이탈리아에 전해져 ≪데카메론≫이 만들어졌으며, 또 다시 영국에 전해져 ≪Canterbury Tales≫가 나왔으며, 이후에 프랑스 등 여러 유럽국가들에 전해졌다. 그러나 이 $quot;액자구조$quot;는 중국에 전해진 적이 없다. 17세기 중엽까지 중국 단편소설집에서 이 $quot;액자구조$quot;를 사용한 것을 볼 수 없다. 17세기 중엽이 되어서야 $quot;액자구조$quot;를 사용한 화본소설집이 $quot;우담화(優曇花)$quot;처럼 잠깐 나타났다가 바로 사라졌다. 이것이 바로 ≪豆棚閑話≫이다. 그런데 ≪豆棚閑話≫이후 이 $quot;액자구조$quot;를 모방한 작품이 결코 나타나지 않았다. 본 논문은 이 $quot;우담화(優曇花)$quot;처럼 잠깐 나타났다가 바로 사라진 $quot;액자구조$quot;를 사용한 ≪豆棚閑話≫를 연구대상으로 하여, 이 소설이 세계문학 중 기타 $quot;액자구조$quot;를 사용한 소설집과 어떤 특징이 있는지, 이러한 특징이 어떻게 중국 문화배경을 반영하고 있는지, 그리고 이 작품의 $quot;액자구조$quot;사용이 중국 고전소설사에 어떤 의의를 담고 있는 지를 연구·검토하고자 한다.

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