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        • KCI등재

          Adding connective tissue manipulation to physiotherapy for chronic low back pain improves pain, mobility, and well-being: a randomized controlled trial

          Seyda,Toprak,Celenay,Derya,Ozer,Kaya,Sevtap,Gunay,Ucurum 한국운동재활학회 2019 JER Vol.15 No.2

          This study aimed to evaluate the effectiveness of connective tissue ma-nipulation (CTM) for improving pain, mobility, and well-being in chronic low back pain (CLBP). Sixty-six patients with CLBP were randomized to three groups: CTM, sham massage (SM) and control groups. The groups got standardized physiotherapy and the related applications 5 days/wk, 3 weeks. Pain intensity, mobility, and well-being (Hospital Anx-iety and Depression Scale [HADS], Oswestry Disability Index [ODI], and Short Form-36 [SF-36]) were assessed before and after the applications. Pain, mobility, and disability improved in all groups (P<0.05). There were differences in resting pain, HADS, and SF-36 scores in CTM, resting pain in SM, and SF-36 scores in controls (P<0.05). Activity pain, HADS scores decreased, mobility and physical component of the SF-36 in-creased in CTM compared to SM (P<0.05). Pain, ODI, and HADS scores decreased, mobility and SF-36 increased in CTM, and ODI scores de-creased in SM compared to controls (P<0.05). In conclusion, pain in-tensity during activity and at night and disability decreased, and spinal mobility increased in all groups. However, CTM showed superiority in improving pain, mobility, and well-being in patients with CLBP.

        • KCI등재

          Flow injection determination of catechol based on polypyrrole-carbon nanotube-tyrosinase biocomposite detectorr

          Seyda,Korkut,Ozoner,Mevra,Yalvac,Elif,Erhan 한국물리학회 2010 Current Applied Physics Vol.10 No.1

          A flow injection catechol biosensor based on tyrosinase entrapped in carbon nanotube modified polypyrrole biocomposite film on a glassy carbon surface has been developed. Amperometric response was measured as a function of concentration of catechol, at a fixed bias voltage of -50 mV at a flow rate of 1 mL/min. The proposed biosensor exhibited impressive analytical performance such as a linear range between 3 and 50 ㎛, a short response time (10 s), a detection limit of 0.671 ㎛ and an excellent operational (with a relative standard deviation of 0.54%) and long-term stability (85% remained after 10th week). A comparison of the analytical parameters of the developed biosensor with polypyrrole/tyrosinase film electrode was performed in the study. CNT was shown to enhance the electron transfer between the electrode and enzyme and capable to carry higher bioactivity owing to its intensified surface area.

        • Das Parteiverbot nach dem Grundgesetz im Lichte der Rechtsprechung des Europäischen Gerichtshofes für Menschenrechte

          Seyda,Emek 헌법이론실무학회 2015 헌법연구 Vol.2 No.2

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

        • KCI등재

          Symmetric Supercapacitor Application of Anhydrous Gel Electrolytes Comprising Doped Tetrazole Terminated Flexible Spacers

          Seyda,T.,Gunday,Emre,Cevik,Ismail,Anil,Omar,Alagha,Hussein,Sabit,Ayhan,Bozkurt 한국고분자학회 2020 Macromolecular Research Vol.28 No.12

          The current research aimed to produce anhydrous gel organic electrolytes with superior performance for high-temperature supercapacitor applications. Within this scope, anhydrous electrolytes were designed by the termination of 1,4- butanediol diglycidyl ether (BDE) with 5-aminotetrazole (AT). The BDE(AT)2 was further doped with phosphoric acid (PA) and 1-Ethyl-3-methylimidazolium tetrafluoroborate (EMT, as an ionic liquid) at varied ratios. The structure of fabricated electrolytes was elucidated with various spectroscopic techniques, and thermal studies confirmed high thermal stabilities and low glass transition temperatures, suggesting that they could be used in a wide temperature range. Different supercapacitor systems, in combination with carbon-based electrodes and BDE(AT)2, BDE(AT)2-0.1EMT, and BDE(AT)2-PA-0.1EMT electrolytes, were constructed. The supercapacitor device in combination with BDE(AT)2-PA-0.1EMT electrolyte, showed the highest ionic conductivity value of 1.2×10-4 S cm-1. The electrode/electrolyte combination demonstrated a maximum specific capacitance (80.4 F g-1), the highest specific energy (2.91 Wh kg-1), and highly effective electrochemical reversibility (up to 2.250 cycles). The supercapacitor device illustrated a better performance at higher temperatures in terms of its specific capacitance value.

        • KCI등재

          Synthesis and Physical Properties of Proton Conducting Polymer Electrolytes Comprising PAM Cross-Linked Flexible Spacers

          Seyda,Tugba,Gunday,M.,A.,Almessiere,Hamide,Aydın,Ayhan,Bozkurt 한국고분자학회 2019 Macromolecular Research Vol.27 No.7

          The design of novel proton exchange membranes with high conductivity and better dimensional stability has become increasingly important due to the need for applications in different devices. The present work shows the acid-doped and crosslinked polyacrylamide (PAM) networks including flexible spaces. To this end PAM was modified with 1,4-butanediol diglycidyl ether (BG) to form PAM35BG and PAM50BG networks, which would afford more space for protonated solvents. The reaction of PAM with BG was monitored by FTIR and 13C CP-MAS NMR. The polymer electrolytes were produced by acid doping at several stoichiometric ratios with respect to the monomer repeat unit of a host polymer. The resulting materials exhibited better thermal, chemical, and electrochemical stabilities and had distinct T g values. Additionally, the pores of the PAM-BG materials were filled with H3PO4 to get PAM35BG0.5H3PO4 and PAM50BG1.0H3PO4. The doping enhanced the proton conductivities of the membranes as high as 0.003 S/cm at 120 oC under an anhydrous atmosphere. The proton diffusion mechanism and the dielectric relaxation were further examined using the complex modulus formalism, M*.

        • KCI등재SCOPUS

          The Presence of Polycyclic Aromatic Hydrocarbons (PAHs) in Grilled Beef, Chicken and Fish by Considering Dietary Exposure and Risk Assessment

          Seyda,Sahin,Halil,Ibrahim,Ulusoy,Suleyman,Alemdar,Selim,Erdogan,Sema,Agaoglu 한국축산식품학회 2020 한국축산식품학회지 Vol.40 No.5

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

          Polycyclic aromatic hydrocarbons (PAHs) are dangerous chemical compounds that can be formed by cooking foods at high temperatures. The aim of this study is to determine the level of contamination of PAH compounds with high performance liquid chromatography (HPLC) on heat treated meat samples and the consumption of PAH compounds in meat samples, as well as the dietary exposure status and possible health risk estimation. In five different heat treated meat samples (meat doner, chicken doner, meatballs, grilled chicken, and fish), the total PAH (Σ16PAH) contamination level was 6.08, 4.42, 4.45, 4.91, and 7.26 μg/kg, respectively. Benzo[a]pyrene (BaP) in meatballs and grilled fish samples had a level 0.70 and 0.73 μg/kg. All of the samples analyzed were found to be below the EU permitted limit (5 μg/kg) in terms of BaP. Estimates of daily intake (EDI) for a total of 16PAH in heat treated meat doner, chicken doner, meatballs, grilled chicken and fish samples were 3.41, 3.71, 2.49, 4.12, and 1.77 ng/kg bw/day, respectively. In this study, the average margin of exposure (MOE) value calculated was found in the range of 179.487 and 425.000 for BaP and PAH4. This study is the first study to provide important information in terms of evaluating the possible health risk that PAH compounds can create in people s diets due to heat treatment of meat and meat products in Sivas, Turkey.

        • KCI등재

          Well-Differentiated Papillary Mesothelioma of the Tunica Vaginalis: A Case Study and Review of the Literature

          Seyda,Erdogan,Arbil,Acikalin,Handan,Zeren,Gulfılız,Gonlusen,Suzan,Zorludemir,Volkan,Izol 대한병리학회 2014 Journal of Pathology and Translational Medicine Vol.48 No.3

          Well-differentiated papillary mesothelioma is an uncommon tumor of the testes that usually presents as a hydrocele. Here, we present the case of one patient who did not have a history of asbestos exposure. The tumor was localized in the tunica vaginalis and was composed of three pedunculated masses macroscopically. Microscopically, branching papillary structures with focal coagulative necrosis were present. In addition to immunohistochemistry, simian virus 40 DNA was also tested by polymerase chain reaction. This report presents one case of this rare entity, its clinical and macroscopic features, and follow-up results.

        • KCI등재

          A novel poly(glycine methacrylate-co-3-thienylmethyl methacrylate)- polypyrrole-carbon nanotube-horseradish peroxidase composite film electrode for the detection of phenolic compounds

          Seyda,Korkut,Ozoner,Faruk,Yilmaz,Asuman,Celik,Bulent,Keskinler,Elif,Erhan 한국물리학회 2011 Current Applied Physics Vol.11 No.3

          A novel amperometric biosensor, based on poly(glycine methacrylate-co-3-thienylmethyl methacrylate)-polypyrrole-carbon nanotube {Poly(GMA-co-MTM)/PPy/CNT} composite matrix, was used for the determination of eighteen phenol derivatives. The enzyme, horseradish peroxidase (HRP) was covalently immobilized to this novel composite polymer matrix. The measurement of the phenolic compounds was carried out by the electrode reduction of the generated phenoxy radical, product of the enzymatic reaction, at a fixed voltage of ―50 mV. Optimization of the experimental parameters was performed with regard to pH, operational potential and hydrogen peroxide concentration. The differences in sensitivity,linear range, detection limit and response time observed for series of phenolic compounds were discussed. The biosensor gave no response to m-cresol, o-cresol and p-cresol. Poly(GMA-co-MTM)/PPy/CNT/HRP composite film electrode retained 80% of its initial activity after the usage of 700 measurements in one month.

        • KCI등재

          Adding connective tissue manipulation to physiotherapy for chronic low back pain improves pain, mobility, and well-being : a randomized controlled trial

          Seyda,Toprak,Celenay,Derya,Ozer,Kaya,Sevtap,Gunay,Ucurum 한국운동재활학회 2019 JER Vol.15 No.2

          This study aimed to evaluate the effectiveness of connective tissue ma-nipulation (CTM) for improving pain, mobility, and well-being in chronic low back pain (CLBP). Sixty-six patients with CLBP were randomized to three groups: CTM, sham massage (SM) and control groups. The groups got standardized physiotherapy and the related applications 5 days/wk, 3 weeks. Pain intensity, mobility, and well-being (Hospital Anx-iety and Depression Scale [HADS], Oswestry Disability Index [ODI], and Short Form-36 [SF-36]) were assessed before and after the applications. Pain, mobility, and disability improved in all groups (P<0.05). There were differences in resting pain, HADS, and SF-36 scores in CTM, resting pain in SM, and SF-36 scores in controls (P<0.05). Activity pain, HADS scores decreased, mobility and physical component of the SF-36 in-creased in CTM compared to SM (P<0.05). Pain, ODI, and HADS scores decreased, mobility and SF-36 increased in CTM, and ODI scores de-creased in SM compared to controls (P<0.05). In conclusion, pain in-tensity during activity and at night and disability decreased, and spinal mobility increased in all groups. However, CTM showed superiority in improving pain, mobility, and well-being in patients with CLBP.

        • Oral Cyclophosphamide and Etoposide in Treatment of Malignant Pleural Mesothelioma

          Gunduz,,Seyda,Mutlu,,Hasan,Goksu,,Sema,Sezgin,Arslan,,Deniz,Tatli,,Ali,Murat,Uysal,,Mukremin,Coskun,,Hasan,Senol,Bozcuk,,Hakan,Ozdogan,,Mustafa,Savas,,Burhan Asian Pacific Organization for Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

          Background: Malignant mesothelioma (MM) is almost always fatal and few treatment options are available. The aim of this study was to evaluate the efficacy of oral cyclophosphamide and etoposide for patients who underwent standard treatment for advanced MM. Materials and Methods: This study included 22 malignant pleural mesothelioma patients who were treated with oral cyclophosphamide and etoposide (EE). Results: The average follow-up period of the patients was 39.1 months. Under the treatment of oral EE, median progression-free survival was 7.7 months [95%CI HR (4.3-11.1)] and median overall survival was 28.1 months [95%CI HR (5.8-50.3)]. The treatment response rates were as follows: 4 patients (27.3%) had a partial response (PR), 12 (54.5%) had stable disease (SD), and progressive disease (PD) was observed in 6 (35.9%). Conclusions: Oral EE can be administered effectively to patients with inoperable malignant mesothelioma who had previously received standard treatments.

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