유산소성 운동 강도가 혈중 알코올 농도에 미치는 영향

오승렬,오상덕,김태욱,박원화 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

This study was to examine the most effective exercise intensity to decrease blood alcohol level under the condition of the same exercise volume after alcohol ingestion The subjects of the study were 7 students who enrolled in physical education major at H University, The blood alcohol levels of subjects were recorded and analyzed in different exercise condition, which were without exercise, HRmax 50% aerobic exercise, HRmax 70% aerobic exercise at each exercise situation(before, immediately after, 65rnins after, and 120mins after exercise). The effects of aerobic exercise on blood alcohol level and the changes in blood alcohol concentration level according to aerobic exercise intensity were as follows : 1. The blood alcohol levels in non-exercise group, HRmax 50% exercise group, and HRmax 70% exercise group illustrated significant difference(p<.05), In post hoc test, there was significant difference between non-exercise group and HRmax 50% exercise group (p<.05). In addition, there was significant difference between non-exercise group and HRmax 70% exercise group(p<.05). However, the blood alcohol levels in HRmax 50% exercise group and HRmax 70% exercise group did not show significant difference(p>.05). 2. The levels of decreasing blood alcohol concentration in the exercise situation(before, immediately after, 60mins after, and 120mins after exercise) showed significant difference(p<.001). 3. The interactive effect between exercise group and exercise situation illustrated significant difference(p<.001). As mentioned above, aerobic exercise was effective to decrease blood alcohol level after alcohol ingestion but under the condition of the same exercise volume the change of blood alcohol levels according to exercise intensity did not show significant difference. In conclusion, the most effective and fastest way to decrease blood alcohol level was HRmax 50% aerobic exercise, that is low intensity, rest after the exercise, and slight physical activity.

슬관절 골관절염 환자에서 근육내 자극요법의 치료 효과

박영규,우종웅,안승렬,김정아,윤도경,박승회,조경환,홍명호 대한노인병학회 2001 대한노인병학회지 Vol.5 No.4

A Method for Improving Object Recognition Using Pattern Recognition Filtering

Seung-Gi Lee,Jin-Lyul Park,Young-Jin Kim,Seung-Hwan Choi 대한전자공학회 2017 대한전자공학회 학술대회 Vol.2017 No.1

In the field of computer vision, many algorithms for object recognition are being researched. Among them, feature-based SURF (Speeded Up Robust Features) algorithm is outstanding in terms of speed and accuracy compared to other algorithms. However, the SURF algorithm has the drawback of failing to recognize objects due to mismatching of corresponding points in detecting corresponding points. This thesis paper has actualized object-recognition system based on SURF and RANSAC (Random Sample Consensus) to enhance object recognition rate, suggesting pattern-recognition filtering. Also, through experiments, the results of object recognition rate was suggested.

Single muscle cell contractile mechanics of aging and T2DM skeletal muscle

( Seung-lyul Oh ) 한국체육학회 2016 국제스포츠과학 학술대회 Vol.2016 No.1

Purpose: The purpose of this study was to examine single cell contractile mechanics and in vivo functions in aging and T2DM skeletal muscle. Method: We recruited participants with eligibility inclusion criteria, and assigned fifteen younger adults (Y, 47.42±6.33), eleven older adults (A, 73.45±5.24), and ten older T2DM patients (AD, 74.75±5.68) to the study. Biopsy samples were taken from vastus lateralis muscle (VL). Chemically skinned single muscle fibers were performed at 15°C for cross sectional area (CSA), specific force (Po), and passive tension. Result: The AD group had significantly lower in CSA than the Y and A groups. However, there was not significant difference in specific force among the groups. The passive tension is significantly lower in the A group relative to the Y and AD groups. Although the Titin-based passive tension was similar to between Y and AD groups, the extracellular matrix (ECM)-based passive tension was significantly greater in the AD group than in the Y and A groups. Additionally, the Titin/ECM ratio was significantly lower in the AD group than in the Y and A groups. Conclusion: These results suggest that the aging with T2DM can increase the passive tension via increasing the extracellular matrix around the skeletal muscle fiber not the Titin protein. We must experiment to find the effects of exercise intervention in older adults with T2DM for prevention of the functional limitations. Also, single muscle cell analysis and in vivo function will be to investigate for confirmation of the association between the effect of in vitro mechanical property and in vivo function after exercise intervention.

Age- and sex-related differences in myosin heavy chain isoforms and muscle strength, function, and quality: a cross sectional study

( Seung-lyul Oh ),( Sang Hoon Yoon ),( Jae-young Lim ) 한국운동영양학회 2018 Physical Activity and Nutrition (Phys Act Nutr) Vol.22 No.2

[Purpose] Declining muscle strength and function are hallmarks of the aging process. This study aimed to determine sex-related differences in myosin heavy chain (MHC) isoforms and muscle mass, strength, and quality with aging. [Methods] This cross-sectional study recruited 53 healthy participants (32 men, 21 women) aged 20-85 years who were divided into four groups: young men (n=17, YM, 29.23±4.51), older men (n=15, OM, 71.87±3.42), young women (n=11, YW, 29.64±4.88), and older women (n=10, OW, 68.1±1.91). Body composition and muscle strength and quality were analyzed. Muscle specimens were obtained from the vastus lateralis in all participants to analyze the type of MHC isoforms. [Results] Men showed a greater age-related decline in skeletal muscle mass (18.6%, p<0.01), lean body mass (10.1%, p<0.05), grip strength (35.3%, p<0.001), isometric strength (29.6%, p<0.001), isotonic power (42.5%, p<0.001), isokinetic strength (up to 44.3%, p<0.001), and muscle quality (up to 24.8%, p<0.01). In contrast, women had significantly lower isometric strength (24.2%, p<0.05), isotonic power (36.5%, p<0.01), and upper-body muscle quality (24.7%, p<0.001) with aging. In addition, the proportion of MHC IIa was significantly lower in OM (p<0.05) and OW (p<0.05) than in YM and YW, respectively. However, the proportion of MHC I was significantly higher in OM (p<0.01) than in YM but was high in both YW and OW. MHC I and MHC IIa negatively and positively correlated, respectively, with muscle strength and function. [Conclusion] These results indicate the existence of sex-related differences in muscle mass, strength, and quality and MHC isoform composition with increasing age. The effects on muscle strength and function with aging were significant in men, but not in women. Higher and lower proportions of MHC I and MHC IIa fibers, respectively, were inversely associated with muscle strength and quality. In particular, Korean YW showed lower muscle strength and quality, and the proportion of MHC isoforms was similar to that in the muscles of OW.

Effect of Resistance Training on Skeletal Muscle Gene Expression in Rats

Seung-Lyul Oh(오승렬),Sang-Duk Oh(오상덕) 한국생명과학회 2013 생명과학회지 Vol.23 No.1

본 연구의 목적은 저항성 운동 후 골격근에서 저항성 관련 유전자를 규명하는 것이다. 연구 목적을 달성하기 위하여 총 32두의 Sprague-Dawley계 수컷 흰쥐를 분양 받은 후 4주차 통제군(4 wks CON, n=8), 8주차 통제군(8 wks CON, n=8), 4주차 운동군(4 wks REG, n=8), 8주차 운동군(8 wks REG, n=8)으로 집단을 분류하였다. 저항성 운동군은 꼬리에 무게를 달고 동물용 사다리(1-m vertical, 85 degree incline)를 오르는 저항성 사다리 운동을 1회 10번, 주당 3일, 4주와 8주간 점증적으로 실시하였으며, 골격근 조직은 저항성 운동 후 장무지굴근(flexor hallucis longus; FHL)을 적출하여 분석에 이용하였다. 적출한 골격근에서 total RNA를 분류한 후, 대규모 유전자 발현분석을 위하여 Illumina RatRef-12 Expression BeadChip을 이용한 Beadarray를 시행하였으며, Beadarray 결과를 확인하기 위해 qPCR (real-time quantitative PCR)를 실시하였다. 유의성 검증은 Beadstudio software를 이용하여 실시하였으며, Beadarray 데이터 중 Detection p-value to <0.01, M-value {M= log2 (condition)-log2 (reference)} to >1.0, DiffScore to >20인 유전자만을 통계적으로 의미 있는 유전자로 선택하였다. 4주차 저항성 운동 후 통제집단에 비해 2배 이상 유의하게 발현이 증가한 유전자는 30개였으며, 6개의 유전자가 감소하였다. 8주차 저항성 운동 후에는 5개의 유전자가 발현이 증가하였으며, 12개의 유전자가 유의하게 감소하였다. 연구결과 다음의 유전자를 포함한 저항성 운동과 근비대와 관련 후보 유전자를 도출하였다; 1) 세포 성장 조절(IGFBP1, PLA2G2A, OKL38); 2) 근육발생(CSRP3); 3) 조직 재생과 근육 발달(MUSTN1, MYBPH); and 4) 비대 모델(CYR61, ATF3, NR4A3); and 5) 당대사(G6PC, PCK1). 이러한 연구결과는 차후 저항성 운동과 관련된 다양한 생리학적 변인을 연구하는데 있어서 기초 자료를 제공할 것으로 생각된다. The aim was to examine resistance exercise-related genes after 8 weeks of resistance training. Thirty-two male Sprague-Dawley rats were divided into four groups: 4 weeks sedentary (4 wks CON, n=8), 8 weeks sedentary (8 wks CON, n=8), 4 weeks exercise training (4 wks REG, n=8), and 8 weeks exercise training (8 wks REG, n=8). The rats were trained to climb a 1-m vertical incline (85-degree), with weights secured to their tails. They climbed 10 times, 3 days per week, for 8 consecutive weeks. Skeletal muscle was taken from the flexor halucis longus after the exercise training. After separating the total RNA, large-scale gene expression was investigated by beadarray (Illumina RatRef-12 Expression BeadChip) analysis, and qPCR was used to inspect the beadarray data and to analyze the RNA quantitatively. The detection p-value for the genes was p<0.01, the M-value {M=log₂(condition)-log₂(reference)} was >1.0, and the DiffScore was >20. In total, the expression of 30 genes significantly increased 4 weeks after the exercise training, and the expression of six genes decreased. At 8 weeks, the expression of five genes significantly increased and that of 12 decreased. Several genes are potentially involved in resistance exercise and muscle hypertrophy, including 1) regulation of cell growth (IGFBP1, PLA2G2A, OKL38); 2) myogenesis (CSRP3); 3) tissue regeneration and muscle development (MUSTN1, MYBPH); 4) hypertrophy (CYR61, ATF3, NR4A3); and 5) glucose metabolism (G6PC, PCK1). These results may help to explain previously reported physiological changes of the skeletal muscle and suggest new avenues for further investigation.

Effects of acute and chronic resistance exercise training on IL-15 expression in rat skeletal muscle

( Seung Lyul Oh ),( Hee Jae Kim ),( Yong An Kim ),( Je Kyung Seong ),( Wook Song ) 한국스포츠정책과학원(구 한국스포츠개발원) 2013 International Journal of Applied Sports Sciences Vol.25 No.2

The aim of this study was to examine IL-15 expression after acute and chronic resistance training in rat skeletal muscle. Thirty-two male Sprague-Dawley rats were divided into sedentary control group (CON, n=8), acute resistance exercise group (ARE, n=16), and chronic resistance training group (CRT, n=8). The rats in CRT were trained to climb a ladder with weights secured to their tail 3 days/week for 8 weeks progressively, whereas acute exercised rats were climbed the ladder 10 times, and then sacrificed. IL-15 concentration in response to acute bout of resistance exercise was markedly increased (p<0.05) and peaked 1 hour after exercise compared to resting level, then returned to the resting level at 6 hours after resistance exercise in both soleus (SOL) and tibialis anterior (TA). After 8 weeks resistance training, significant higher concentration of IL-15 in SOL was found compared to the CON (p<0.05), while there was no significant change in IL-15 level in TA. These data are the first to demonstrate the changes in IL-15 level after the acute and chronic resistance exercise according to muscle fiber types.

Effects of conjugated linoleic acid/ n-3 and resistance training on muscle quality and expression of atrophy-related ubiquitin ligases in middle-aged mice with high-fat dietinduced obesity

( Seung-lyul Oh ),( Sang-rok Lee ),( Jeong-su Kim ) 한국운동영양학회 2017 Physical Activity and Nutrition (Phys Act Nutr) Vol.21 No.3

[Purpose] To investigate the effects of conjugated linoleic acid (CLA)/n-3 supplements and resistance exercise training (RT) for 20 weeks on muscle quality and genes related to protein synthesis/degradation in middle-aged mice with high-fat diet (HFD)-induced obesity. [Methods] Nine-month-old C57BL/6 male mice were randomly assigned to five groups: 1) normal diet (C), 2) high-fat diet (H), 3) H+RT (HRT), 4) H+CLA/n-3 (H-CN), and 5) H+RT+CLA/ n-3 (H-RTCN). HFD groups were given a diet containing 60% fat for 20 weeks, and exercised groups underwent progressive RT using weighted ladder climbing. The CLA/n-3 mixed diet contained 1% CLA and 1% n-3. Grip strength was assessed, and triceps were removed. RT-PCR was used to analyze transcript levels. [Results] Grip strength of the H group was significantly lower than that of the C group; however, those in the H-CN, H-RT, and H-RTN groups were significantly greater than that in the H group. However, the muscle quality was significantly greater only in the H-RT group compared with the H and H-CN groups. Akt expression decreased in the H-CN, H-RT, and H-RTCN groups compared with those in the C and H groups, whereas mammalian target of rapamycin expression increased in the H, H-CN, H-RT, and H-RTCN groups compared with that in the C group. However, atrogin1 was significantly downregulated in the H-RTCN group compared with that in the H and H-CN groups, and MuRF1 expression was also decreased in the H-RT and H-RTCN groups. Interestingly, atrogin1 and MuRF1 were downregulated in the H-RTCN group compared with that in the H-CN group. [Conclusion] HFD-mediated gene expression involved in protein degradation was attenuated following 20-week RT with CLA/n-3. Furthermore, RT with or without CLA/n-3 improved grip strength and muscle quality in middle-aged mice during HFD. Therefore, RT with CLA/n-3 during HFD may improve muscle strength and quality by suppressing protein degradation.

신생혈관녹내장에서 Molteno Implantation 시 안압의 변동을 조절하기 위한 Laser - Releasable Intracameral Ligature

유승렬(Seung Lyul Yu),이호용(Ho Yong Lee),엄기방(Ki Bang Uhm) 대한안과학회 1995 대한안과학회지 Vol.36 No.10

해상풍력발전기 자켓 지지구조물의 신뢰성 기반 최적설계

이승훈(Seung-Hoon Lee),이연승(Yeon-Seung Lee),이지현(Ji Hyun Lee),최병렬(Byung-Lyul Choi),최동훈(Dong-Hoon Choi) 대한기계학회 2014 대한기계학회 춘추학술대회 Vol.2014 No.4-2