각화극 세포종, 기저세포암과 편평상피암에서 p21과 p53의 표출 양상

윤성웅,조현득,양승하,김의한 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

Background: The function of the p53 protein was known to regulate cell proliferation by inhibiting cells in S phase, so DNA damaged cell proliferation was not occured by apoptosis. p21 is a cyclin dependent kinase inhibitor induced by wild type p53. p21 is thought to mediate the signal of p53 induced by DNA damaged agents and to arrest the cell cycle in G1 phase. p21 and p53 were expressed in many malignant tumors, and its role in oncogenesis, tumor progression and prognosis were important. The authors analyzed immunohistochemical expression of mutant p53 and p21 protein in keratocarcinoma, squamous carcinoma and basal cell carcinoma. Method: Eight cases of keratocarcinom, fifteen cases of squamous cell carcinoma and twenty cases of basal cell carcinoma were immunohistochemically stained with p21 and p53 monoclonal antibodies. Results: 1. The positive reaction of p21 protein and p53 protein in keratocarcinoma were samely observed In 7/8 cases(87%) and the positive reaction of p21 and p53 protein in squamous cell carcinoma were samely observed in all cases(100%) 2. The reaction pattern of p21 protein and p53 protein showed that positive reaction in both basal layer and keratinocytes concomitantly were more common observed than that in basal layer only. But the case of positive reaction in only keratinocytes was not observed. 3. In basal cell carcinoma, the positive reaction of p21 protein werw seen in 5/20 cases(25%) and that of p53 were positive reaction in 15/20 cases(75%). p21 protein also showed positive reaction in cases of p53 protein positive cases. 4.The reaction pattern in basal cell carcinoma showed more intense reaction in peripheral portion than central portion of tumor nests, which suggested that tumor cells in the peripheral portion was composed of less mature cells than that of contal portion. The mutant p53 protein had lost of capability of inducing p21 protein, So in cases of p53 protein wae negative, the p21 protein theoretically showed negative reaction. But the p21 protein positive cases were observed in p53 positive cases, which was suggested that the p21 protein was induced by the p53 independent pathway. The prognosis appeared to be good in cases of both p21 protein (+)and p53 protein(+) cases than that of p21(-) and p53(+).

테라 시질라타 슬립 연구

김승욱 경희대학교 디자인연구원 2004 예술· 디자인학연구 Vol.7 No.1

The terra sigillata slip coatings used by early Roman and Greek potters to produce their characteristic ware can be adapted for use by contemporary ceramists to provide a versatile finish for a variety of ceramic surfaces. In terms of composition, terra sigillata slips closely resemble standard clay slips prepared from a clay and clay body. This study is to develop a basic and colored terra sigillata slips from domestic clay and clay body for ceramic surface decoration.

락소를 위한 소지 및 유약에 관한 연구

김승욱 慶熙大學校 1997 論文集 Vol.26 No.-

The purpose of this study is to develop low-fire clay body and glaze for Raku technique. The results were summarized as follows. 1) Sanchang clay composition proved better at lowfire Raku technique. 2) Commercial leadless frit DY220, DY8016 are strong flux to promote even melting at temperatures below 1.000℃ 3) Best basic glaze receipe was frit DY220 70%, frti DY 8016 10%, Ball Clay 20% at 960℃ 4) Additions of 8% tin oxide will give a rich white opaque glaze with fritted transparent glaze and raku base glazes can be adulterated with oxides to give a wide range of colours.

자가 골수 기질세포이식을 이용한 대퇴골두의 무혈성 괴사 및 장관골 골낭종의 치료

이승구,권순용,정진화,정도현,이주형,최숭욱 대한정형외과학회 골.연부조직이식학회 2003 대한골.연부 조직이식학회지 Vol.3 No.2

과재하중 재하에 따른 역 T형 옹벽의 활동거동에 관한 수치해석

유남재,이명욱,박병수,이승주 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.B

This paper is experimental and numerical research about the sliding behavior of cantilever retaining walls resisting surcharge loads. In experimental research, centrifuge model tests at the 1g and 40g-level were performed by changing the location of model footing and its width. Bearing capacity of model footing and characteristics of load-settlement and load-lateral displacement of retaining wall were investigated. Test results of bearing capacity were compared with modified jarquio method, based on the limit equilibrium method with elasticity theory. For the numerical analysis, the commericially available program of FLAC was used by implementing the hyperbolic constitutive relationships to compare with test result about load-settlement and load-displacement of retaining wall, bearing capacity of strip footing.

Analyst Forecasts and Herding Behavior: Some Evidence from the Stock Market in Korea

( Seung Woog Kwag ) 경희대학교 사회과학연구원 2009 2009특집호 Vol.2009 No.-

This paper presents some empirical analysis of analyst herding and optimism phenomena in the Korea stock market. Employing 11640 samples, I find the evidence suggest that analyst optimism is widespread across the stock market in Korea. Systematic herding behavior of analysts is also observed as analysts forecast earnings farther out into the future. For the 1988~2003 period, the mean IR unanimously decreases as the forecast period increases from the one-year to the two-year period. As observed in the US, as the forecast horizon lengthens, the forecast accuracy deteriorates.

The P/B Ratio : Level Versus Change

( Seung Woog Kwag ) 한국재무관리학회 2013 財務管理硏究 Vol.30 No.3

This study sheds a new light on the role of the change in price-to-book ratio (PB) relative to the level of price-to-book (P/B) ratio in predicting stock performance. A simple portfolio return analysis shows that the PB is a more effective investment heuristic than the P/B ratio. The contemporaneous panel regression with fixed and random effects discloses that both the PB and the P/B ratio are positively and significantly related to stock returns. The proxy panel regression with fixed and random effects holds that the P/B effect becomes contrarian, while the PB effect remains positive.

Social Capital versus Income in Happiness Equation: A Global Perspective

Seung Woog Kwag 한국국제경영관리학회 2017 국제경영리뷰 Vol.21 No.4

행복은 대부분의 사람들이 궁극적으로 이루고자 하는 삶의 목적이다. 우리는 행복해지기 위해 일하고, 여행하고, 운동하고 공부하고 사랑한다. 우리가 하는 모든 것들은 행복을 성취하기 위한 소망 섞인 노력이라고 해도 과언이 아니다. 행복에 대한 전통적 접근법은 행복의 필요조건으로 소비, 소득, 물가, 그리고 GDP와 같은 경제적 요인의 적절한 수준을 강조하고 이들이 행복에 미치는 영향을 분석하는데 초점을 맞춘다. 그러나 상식적, 정서적 관점뿐만 아니라 학문적 측면에서 바라보아도 사람들 간의 사회관계망, 교육, 정신건강, 여가생활 같은 비경제적 요인이 행복에 미치는 영향을 간과할 수 없다. 본 연구는 행복의 경제적 요인과 비경제적 요인에 관한 선행연구를 체계적으로 분석, 대조하여 행복의 조건에 대한 균형 잡힌 시각을 제공한다. 특히 행복지수에서 그 중요성을 점점 높여 가는 사회관계망의 역할을 재조명하고자 한다. 이를 위해, 2013년도부터 2016년도에 이르는 OECD 자료를 활용한 실증분석의 결과, 사화관계망은 소득이나 물가와 같은 전통적, 경제적 요인과 더불어 행복을 유발하고 증가시키는 중요 요인임을 확인하였다. 삶의 질은 소득이나 소비증가 또는 보조금만으로 향상시킬 수 있는 경제적 과제가 아니다. 사회구성원간의 건전한 사회관계망을 확립하고 확장하는 것도 그에 못지않게 시급하다. Happiness is the final destination that most people aspire to reach. We work, travel, exercise, study, or love to be happy. It is no exaggeration to say that things we do are all hopeful ways to reach happiness. The national ranking of happiness often manifests in the emotions of people living in the ranked countries and influences their economic policies. The constitutions of industrialized countries honor the human right of pursuing happiness. Happiness seems the ultimate destination of human life. However, the traditional approach to happiness is quite limited to analyze economic factors such as consumption, income, inflation, and GDP, although we all feel and recognize that happiness cannot be defined only by a set of economic variables. A long list of recent studies on social capital broadens the scope of the happiness equation by showing that social network and relationships are the essential elements of happiness. The present study systematically reviews and contrasts the happiness studies from two different analytical perspectives: economic and social. The World Happiness Report, the Gallup-Healthways Global Well-Being Index, and the OECD better life data all provide empirical evidence that social capital contributes to increasing happiness in addition to economic factors. A happy individual is likely to be a person who has sufficient income to meet basic needs and a network of good social support. This finding also suggests that policy makers build a stronger social network system that integrates healthcare, welfare, and human rights. Human-like life is composed of not only wealth but also mindful human network. We conclude the study by suggesting necessary changes in welfare policies and proposing relevant future research.

Stock Price Predictability of Financial Ratios and Macroeconomic Variables

Seung Woog Kwag,Yong Seog Kim 대한산업공학회 2013 Industrial Engineeering & Management Systems Vol.12 No.4

The present study examines a set of financial ratios in predicting the up or down movements of stock prices in the context of a securities law, the Sarbanes-Oxley Act of 2002 (SOA), controlling for macroeconomic variables. Using the logistic regression with proxy betas to alleviate the incompatibility problem between the firm-specific financial ratios and macroeconomic indicators, we report evidence that financial ratios are meaningful predictors of stock price changes, which subdue the influence of macroeconomic indicators on stock returns, and more importantly that the SOA truly improves the stock price predictability of financial ratios for the markup sample. The empirical results further suggest that industry and time effects exist and that for the markdown sample the SOA actually deteriorates the predictive power of financial ratios.

Innovative Macroeconomic Value Determinants

( Seung Woog Kwag ),( Meng Qing Yin ),( Mi Jeong Choi ),( Sang Whi Lee ) 한국재무관리학회 2013 財務管理硏究 Vol.30 No.1

In this paper, we test a captivating proposition that the innovative (difference) and interactive terms of macroeconomic variables significantly improve our understanding of the stock return movements. We revisit a prominent issue on the association of the stock return with macroeconomic variables such as default risk premium, term structure of interest rates, growth in GDP and inflation and provide an innovative perspective on the obsolete issue. Using the S&P 500 Industrial Composite Index, we report that the innovative and interactive terms of the variables appear to be significant determinants of the stock return. Our findings suggest that other return models take the innovative and interaction effects into account.