http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Seung-Bun (검색결과 98 건)
- 무료
- 기관 내 무료
- 유료
-
전이성십이지장 내분비암으로 항암화학요법 시행 받고 완전 관해 1년 후 발생한 십이지장 선암 1예
( Bun Kim ),( Ji Hye Heo ),( Joo Won Jung ),( Moon Jae Chung ),( Jeong Youp Park ),( Seung Min Bang ),( Si Young Song ),( Seung Woo Park ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.1
위장관내분비암으로 치료 후 동일 부위에서 선암이 발생한 예는 극히 드물다. 저자들은 전이성 십이지장 내분비암으로 항암치료 받고 완전 관해 1년 후 같은 부위에서 선암이 발생하여 보고하는 바이다. 60세 남환은과거력상 30년 전 콩팥결핵으로 결핵 치료받았다. 한달 간의 전신 무력감과 흑색변으로 2009년 6월 외부병원 내원하여 시행한 검사상 십이지장암과 간전이 의심되어 본원으로 전원되었다. 내원 당시 혈압 130/80 mmHg, 맥박 92회, 체온 36.8도이었다. 일반혈액검사상 WBC 4,730/mm3, Hb12.4 g/dL, platelet 144,000/mm3, 혈청생화학검사상 Bun/Cr 17.7/1.16 mg/dL, AST/ALT 15/13IU/L이였다. 종양표지자는 CEA 0.73 ng/mL, CA 19-9 1.8U/mL이었다. 본원에서 시행한 상부위장관내시경상 십이지장의 상부하행각에 궤양융기형 덩어리가 발견되었다. 조직검사상 십이지장에서 poorly differentiated neuroendocrine carcinoma 진단되어 십이지장 내분비암 및 간전이로 2009년 11월까지 6차례 5-FU (1000 mg/m2, Day1~3)/Etoposide(100 mg/m2, Day1~3)/Cisplatin (70 mg/mg2, Day1) 항암치료 후 영상 및 상부내시경 검사상 완전관해 소견 보였으며 이후 정기적 추적관찰 중이었다. 2011년2월 시행한 상부위장관내시 경상 이전 십이지장 병변에 새롭게 생긴 용종으로 조직 검사 시행하여 선암 진단되었다. 영상 검사상 간 S6/7,S7 두군데에 전이 의심되어 intraop RFA 고려하고 2011년 2월 28일 수술 시행하였다. 십이지장 선암은 8번, 12번, 13번 림프절 확장 소견 보여 병합절제와 췌두부 절제술을 시행하였다. 수술 중 초음파로 간종괴는 찾을 수 없었으나 수술전 시행한 MRI상 간우정맥우연을 따라 종괴가 2개 관찰되어 간우후구역절 제술을 함께 시행하였다. 수술 후 병리 조직 검사상 간 조직은 염증 소견 보이고 십이지장은 선암 진단 되었다. 최종적으로 십이지장 선암은 pT1bN0M0으로 1기로 진단되어 추가 항암치료 없이 외래 경과 관찰 중이다. 저자들은 전이성 십이지장 내분비암으로 항암치료 받고 완전 관해 되었으나 1년 후 같은 부위에서 선암이 발생하여 수술 시행후 완전 절제 되어 보고하는 바이다.
-
Dimethyl-β-Cyclodextrin을 이용한 Omeprazole의 대체투여경로 개발
정미분,박승현,김하형,이광표 중앙대학교 약학연구소 1996 약학 논총 Vol.10 No.-
For the purpose of increaing the stability and bioavailability of omeprazole(OME), inclusion complexes of OME with demethyl-β-cycoldextrin(DMβCD) and hydroxypropyl-β-cyclodextrin(HPβCD) were prepared by freeze drying method. The interactions of OME with DMβCD and HPβCD in aqueous solutions and in solid states were investigated by solubility study. IR spectroscopy and DSC. The type of OME-DMβCD inclusion complex was found to be classified as Bs-type on phase solubility diagram, and the stoichiometric ratio of OME-DMβCD incousion complex was a 1:2 and stability constant was 359.46M^-1. The OME-HPβCD inclusion complex appeare to be AL type. The stoichiometric ratio was found to be 1:1, and stability constant was 34M^-1. Clear differences in a IR spectra and DSC curves were observed between the inclusion complex formation at pH 6.8. The mean dissolution time(MDT). which represents the degree of the rapidity of dissolution rate, was increased in the order of OME-DMβCD I.C(0.60) < OME-HPβCD I.C.(0.71) < OME-DMβCD P.M.(7.23) < OME-HPβCD P.M.(10.06). In order to compare simultaneously the intrinsic absorptivity of OME in the jejunum and nasal cavity of rats, the in situ nasal and jejunal perfusion method was employed as a new trial. The in situ recirculation study revealed that OME-CDs inclusion complexes rate proportionally increased the absorption of OME in nasal cavity(N) and the jejunum(J) of rats. The decreasing order of apparent OME permeability(Papp:cm/sec×10-5), corrected for surface area of absorption was as follows : 8.77±0.18(N, OME-DMβCD). > 5.97±0.17(N. OME-HPβCD) > 4.84±0.02(J. OME-DMβCD). 3.50±0.25(J. OME-HPβCD) at IPB pH 7.4. The present results suggest that OME-DMβCD inclusion complex may serve as a potential means for the nasal delivery of OME.
-
김기웅,홍승분 이화여자대학교 동작과학연구소 2004 이화체육논집 Vol.8 No.-
This study was designed to investigate the relative effectiveness of practice schedulings(massed vs. distributed practice) both on performance and learning of a continuous motor skill. Practice schedulings were manipulated by three groups in terms of the length of the inter-trial intervals(10, 20, 30 seconds). Massed practice was experimentally manipulated with 10s inter-trial intervals and distributed practice was with 20s and 30s inter-trial intervals. The subjects were consisted of 30 right-handed female ndergraduate students and were randomly assigned into three different groups. Subjects were instructed to pursue a target on disc with and-held stylus. The time on target(TOT) was measured as the dependent variable. The acquisition phase were consisted of 10 blocks of five trials. After twenty four hours, retention tests were conducted for a block of trials in the condition of the same speed of acquisition phase(40RPM). Two transfer tests were performed in the two different speed conditions. The first was conducted in slower speed(30 RPM) than in acquisition phase, and the second was conducted in faster speed(50 RPM). Analysis revealed that the main effects of group and block were statistically significant in acquisition phase. There was also statistically significant interaction effect between group and block. However, in retention and two transfer tests there were no statistically significant effects. The results showed that performance scores were consistently better for the distributed group(30s inter-trial intervals), though not statistically significant. In sum, the results indicated that the distributed practice was generally more effective in the learning and performance of continuous task as the pursuit rotor than the massed practice.
-
유양경,고성희,김귀분,정승희 성인간호학회 2004 성인간호학회지 Vol.16 No.1
Purpose: This study was done to identify the degree that perceived social support effects the self esteem of the elderly. Method: A structured questionnaire was administered to 203 elderly subjects from April 2003 to June 2003. The data were analyzed with an SPSS program for descriptive statistics, Pearson's correlation coefficients. t-test, ANOVA, and stepwise multiple regression. Result: The level of social support was moderate; family support received the highest score among sources of support. In types of support, appraisal support was the highest score and material was the lowest. The level of self esteem was also moderate. The score of social support showed a slightly high positive correlation with self esteem. In general characteristics, several variables were significantly related to self esteem. The most powerful predictor of self esteem was material support by family and the variance explained was 19.6%. A combination of material support by family, informational support by relatives, perceived economic status, perceived health status, and having a subject to depend on accounted for 39.8% of the variance in self esteem of the elderly. Conclusion: To increase the self esteem of the elderly, it is necessary to consolidate material support by family.
-
( Bun Kim ),( Moon Jae Chung ),( Se Woo Park ),( Jeong Youp Park ),( Seung Min Bang ),( Seung Woo Park ),( Si Young Song ),( Jae Bock Chung ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: An association between obesity and unfavorable outcomes for various types of malignancy has been established. Nevertheless, the impact of visceral obesity on outcomes in pancreatic cancer is still unknown and controversial. The aim of this study was to uncover an association between visceral obesity (VO) and pancreatic cancer outcomes. Methods: We retrospectively reviewed 499 patients in pancreatic cancer who were diagnosed and treated in the Severance Hospital from January 2006 to December 2011, and collected the data of the clinical features, pathologic fi nding, staging, tumor marker and history of surgery, radiation therapy or chemotherapy. In this study, progression free survival (PFS) and overall survival (OS) were used as factors of cancer prognosis to evaluate association with visceral fat (defi ned as an abdominal fat volume distribution using CT scan obtained from a slice with a disc reference (L3-L4); the percentage of visceral fat to total fat area (VF%) at initial diagnosis. Results: Compared to the low visceral obesity group (low-VO group, n=260), the high visceral obesity group (high-VO group, n=239) was mostly male (68.2% vs. 31.8%, p<0.001), and was more likely to have current smoking status (29.7% vs. 17.7%, p<0.001), current alcohol intake status (52.3% vs. 26.4%, p<0.001) and diabetes mellitus (54.4% vs. 31.9%, p=0.028). The PFS and OS were found to be signifi cantly shorter by the Kaplan-Meier method in the high-VO group than in the low-VO group (PFS: p=0.044, OS: p=0.013). In addition, the higher percentage of visceral fat was correlated with more lymph node metastasis and shorter OS (correlation coeffi cient: 0.165, p=0.011 and -0.107, p=0.017, respectively). Conclusions: In patients with pancreatic cancer, VO at the time of diagnosis is associated with negative outcomes, such as shorter PFS and OS.
-
-
-
-
자극의 속도와 이동거리가 농구 패스의 계획과 실행 및 정확성에 미치는 영향
홍승분 ( Seung Bun Hong ) 한국스포츠심리학회 2009 한국스포츠심리학회지 Vol.20 No.4
이 연구의 목적은 자극의 이동속도와 이동거리가 패서의 기술수준별로 정확한 패스 동작을 수행하는데 필요한 동작계획시간과 동작실행시간, 그리고 패스의 타이밍 정확성에 어떠한 영향을 미치는지 알아보는 데 있다. 이를 위해 초보자 15명과 숙련자 15명의 대상에게 불빛 자극의 이동속도(1.5m/s, 3.0m/s, 4.5m/s)와 이동거리(2m, 4m)가 다른 과제 상황에서 불빛 자극이 목표지점에 도달하는 시점과 일치되게 패스를 수행하도록 하였다. 실험과제는 각 조건 당 5회씩 총 30회가 무선으로 제시되었으며, 매 시행마다 추정반응시간, 동작시간, 그리고 타이밍의 정확성을 측정하였다. 그 결과, 초보자와 숙련자 모두 자극의 이동속도가 동일한 조건에서는 이동거리가 길어질수록 추정반응시간과 동작시간도 길어지는 것으로 나타났다. 단, 숙련자의 경우, 자극이 느린 속도로 이동할 때에는 자극이동거리 간 동작시간의 차이는 나타나지 않았다. 절대오차는 느린 속도로 이동한 경우를 제외하고는 중간조건과 빠른 조건 모두 자극의 이동거리가 길어질수록 타이밍 정확성은 높아졌다. 또한 초보자와 숙련자 모두 자극이동거리가 길수록 패스의 타이밍 정확성은 높은 것으로 나타났다. The study was to investigate the effects of ball receiver`s moving speed and moving time(in distance) on passer`s movement planning(measured as estimated RT), movement time, and ultimately on temporal accuracy(timing error) of passed ball. Fifteen novice players along with fifteen expert players were required to make a total of 30 passes in coincidence with an experimentally manipulated moving light signal in randomly presented six different conditions, i.e., in three differing light speed(1.5m/s; 3.0m/s; 4.5m/s) and in two differing moving time(operationally manipulated in moving distance: 2m or 4m). Analyses of data disclosed that moving stimulus velocity and stimulus duration had differential effects on eRT(estimated reaction time), MT(movement time), and ultimately on timing error as a function of skill level, respectively. Analyses of eRT and MT data using three-way ANOVA with repeated measures revealed eRT and MT were smaller when there was less time available as resulted from increasing stimulus velocity with reduced moving duration. Timing error was greater when stimulus velocity was faster and duration was shorter, but expert were more accurate than novices in the all stimulus conditions. These results were interpreted to mean that moving velocity and moving duration served as the major determinants of temporal accuracy of ball passing.
-
홍승분(Hong Seung-Bun),문화실(Moon Hwa-Sil) 한국체육과학회 2011 한국체육과학회지 Vol.20 No.2
The purpose of this study was to investigate the constructs of sport demotivation. To explore the constructs, four open-ended questions were presented to 144 collegiate athletes who are belong to 8 different sport teams. With the inductive and qualitative content analysis, 7 factors were emerged and named for the sport training demotivation; reduced physical condition, excessive training, psychological readiness deficiency, training program dissatisfaction, sport setting, interpersonal problems between teammates, and less skilled performance. And for the sport competition demotivation, 6 factors were classified; negative psychological condition, reduced physical condition, competition leading position, loss of control, less skilled performance, and interpersonal problems between teammates.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
