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Cho, Kyung-Sam,Kim, Si-Young,Park, Jai-Kyung,Choi, Seung-Hoon,Chung, Se-Young,Yoon, Hwi-Joong 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1
Kyung Sam Cho¹Si Young Kim¹, Jai Kyung Park²,Seung Hoon Choi³,Se Young Chung⁴, Hwi Joong Yoon¹¹College of Medicine, ²East-West Medical Research Institute, ³College of Oriental Medicine, ⁴College of Pharmacology, Kyung Hee University,Seoul, Korea. The Anti-cancer Effect of Oriental Medicine Chung-Ri-Ja-Gam-Tang in the Mouse with Metastatic Lung Cancer. Proceedings of International Symposium on East-West Medicine, Seoul. 231-243, 1999.-The oriental medicine Chung-Ri-Ja-Gam-Tang is an herbal medicine which has been used for pulmonary diseases and known as having immune stimulatory effects. It has been known effective in lung cancer. So we studied the effects and the mechanisms of this herbal medicine it the mouse with metastatic lung cancer. The metastatic lung cancer of the mouse was produced with melnoma cell line(B16BL/6).5×10□/mouse tumor cells were injected intravenously to the CDF1 mouse via tail vein. The mice were divided 4 groups. The first group was treated with 50mg/kg extract of Chung-Ri-Ja-Gam-Tang per oral for 10 days after cancer cell injection, second group treated with saline after cancer cell injection, the third group with medicine without cancer cell, and the last group with saline only. After 10 days treatments some of the mice were scarificed and the lung and spleen was removed. The survival duration, weight change, the number of metastatic cancer nodule of the lung, the NK cell activity, the capacity of cytokines(INF-γ,INF-α,IL-2) production and the proliferation activities of mouse lymphocytes were measured. The surival times of the group 1 mice were longer and the weight loss was less than the group 2 significantly. The number of the metastatic nodule of the lung were decresed in the group 1 than the group 2. The production of INF-γ,was increase in group 2 than group 3 and 4, IL-2 production was increased in group 1 than group 2,3,4 significantly. There was no difference in TNF- α production and proliferation activity of lymphocyte in each group. The NK cell activity was significantly increased in group 1 than group 2,3,4. We conclude that the Chung-Ri-Ja-Gam-Tang has the effect of increasing the NK cell activity of the CDF1 mouse with metastatic lung cancer(B16BL/6). And it is suggested that the increased production of the IL-2 is the mechanisms of enhanced NK cell activity.
음향방출 파형 파라미터 필터링 기법을 이용한 실시간 음원 분류
조승현(Seung Hyun Cho),박재하(Jae Ha Park),안봉영(Bongyoung Ahn) 한국비파괴검사학회 2011 한국비파괴검사학회지 Vol.31 No.2
음향방출기법은 대형 구조물의 구조건전성감시(SHM)를 위한 매우 효율적인 방법이지만, 롤러코스터 지지구조물처럼 승용물의 운행으로 인한 매우 큰 잡음이 일상적으로 존재하는 경우에는 균열 진전 신호만을 분류하여 실시간 감시를 수행하기가 쉽지 않다. 이와 같은 문제의 해결을 위해 본 연구에서는 실시간으로 음원의 분류가 가능한 파형 파라미터 필터링 기법을 제안하였다. 파형 파라미터 필터링 기법은 음향방출 신호의 파형 파라미터를 이용하여 음향방출 히트를 사전에 필터링함으로써 실시간으로 감시하고자 하는 대상 음원만을 분류해내는데 매우 유리한 점이 있다. 다양한 음원에 대해 음향방출 파형 파라미터를 측정 및 분석하여 제안한 기법의 타당성을 살펴보았다. 또한, 파형 파라미터 필터가 내장된 음향 방출 시스템을 구축하고 이를 실제 롤러코스터 지지구조물에 적용하여 실시간 균열진전 감시를 위한 가능성을 타진하였다. The acoustic emission(AE) technique is a well established method to carry out structural health monitoring(SHM) of large structures. However, the real-time monitoring of the crack growth in the roller coaster support structures is not easy since the vehicle operation produces very large noise as well as crack growth. In this investigation, we present the waveform parameter filtering method to classify acoustic sources in real-time. This method filtrates only the AE hits by the target acoustic source as passing hits in a specific parameter band. According to various acoustic sources, the waveform parameters were measured and analyzed to verify the present filtering method. Also, the AE system employing the waveform parameter filter was manufactured and applied to the roller coaster support structure in an actual amusement park.
당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구
한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4
Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.
Distribution of the Fairy Pitta (Pitta nympha) in the South Korea: A focus on protected areas
Gil-Pyo Hong(홍길표),Jae-Hoon Kim(김재훈),Seul-Gi Seo(서슬기),So-Yeon Cho(조소연),Bo-Yeon Hwang(황보연),Jong-Hyun Park(박종현),Seung-Yeon Lee(이승연),Ga-Young Kim(김가영),Wan-Hee Nam(남완희),Ha-Cheol Sung(성하철) 한국조류학회 2021 한국조류학회지 Vol.28 No.2
국내 팔색조(Pitta nympha) 분포 현황을 알아보고자 전국 국립공원 등 보호지역 중심으로 총 19개 지역을 조사하였고, 전문가 네트워크를 통해 자료를 보강하였다. 전국 19개 지역을 조사한 결과 북한산, 지리산 등 내륙지역 7개 국립공원에서는 팔색조가 확인되지 않았고, 경남 거제, 남해, 해남, 장흥 고흥 등 남해안과 인접한 12개 지역에서 팔색조 서식이 확인되었다. 또한 전문가 네트워크를 통해 수집한 팔색조 출현 위치 정보 82건을 분석한 결과, 전국 8개 광역지자체 모두 팔색조 서식이 확인되었고, 내륙지역(26.8%)보다 해안지역(73.2%)에서 더 많이 출현하였다. 연구 결과를 종합해보면, 우리나라의 팔색조는 주로 제주도와 남해안 지역을 중심으로 많이 분포하며, 그 보다 적은 개체수가 내륙 지역에 넓게 분포하고 있는 것으로 나타났다. The present study investigated the current distribution of Fairy Pitta (Pitta nympha) in South Korea. A total of 19 study areas, including protected areas such as national and provincial parks in South Korea were surveyed, and additional data obtained from an expert network. According to the results, Fairy Pitta was absent in seven inland national parks, including Mt. Bukhan and Chiri parks. Fairy Pitta inhabited 12 areas near the southern coast of South Korea, including Geoje, Namhae, Haenam, Jangheung, Goheung, and Gyeongnam Province. The analysis results of 82 datasets obtained from experts with regard to the locations where Fairy Pitta have been spotted showed that the bird inhabits all the eight metropolitan regions in South Korea, and is more frequently spotted in coastal areas (73.2%) than in inland areas (26.8%). The findings demonstrate that Fairy Pitta is mainly distributed in Jeju Island and the southern coast of South Korea, and is distributed in inland areas at relatively lower numbers.
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
평금형 압출용 금형의 NC 가공 S/W 개발에 관한 연구
조승래,이춘만,박태원 國立 昌原大學校 産業技術硏究所 1998 産技硏論文集 Vol.12 No.-
Square dies are widely used for hot extrusion processes with high production rate. Especially, such dies have some advantages in manufacture of aluminum products having arbitrary shapes of cross section, because aluminum alloys can be manufactured without lubrication at a relatively low temperature. The recent development of extrusion technology has brought high precision products with thin thickness. However, the design and manufacture of square dies mainly relies on experience of industrial engineers, it often takes much lead time due to the trial-and-errors of the engineers. To overcome such difficulty, this study develops a method of automatic generation of NC codes for the manufacture of extrusion square dies. This method utilizes both CAD data of a product and database associated with die design parameters, and finally generates NC codes for an aluminum product having an arbitrary shape of cross sections. Specifically, three types of NC codes are generated for : (1) Wire-cut EDM cutting of square dies, (2) Wire-cut EDM cutting of electrodes for die land, and (3) machining of the electrodes. To demonstrate the effectiveness of the method, it is applied to a practical example. The result shows that the method can reduce the lead time for the design and manufacture of square dies as well as eliminating engineers own experience.
趙勝鎬,安世雄,朴鐘沅 弘益大學校 科學技術硏究所 1996 科學技術硏究論文集 Vol.7 No.1
In this paper theoretical analyses are performed on the load sensing system of excavator and databases are constructed for the valve opening areas, pump horce power control and for load sensing regulator. For hydraulic components modularized modelings are carried out, which is expected to be utilized for software development of fluid power system. Through simulation an information of any point in fluid power circuit can be obtained.