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金義慶,鄭秉憲,李聖淵,朱麟源 한국산림경제학회 2002 산림경제연구 Vol.10 No.2
본 연구는 밤, 잣, 대추에 대하여 이루어지고 있는 최소시장접근물량에 대한 수입관리제도의 문제점을 살펴보고 그 개선방안을 도출하는데 목적이 있다. 주요 결과를 보면 밤의 경우 1995년 이후 평균 10%정도의 낮은 수입이행률을 보이고 있으며, 잣의 경우 환율 급변에 의한 환차손으로 수입관리기관이 손해를 보거나 시장조절기능도 미약하다는 문제점을 가지고 있는 것으로 나타났다. 따라서, 수입관리방식은 잣의 경우 현재의 국영무역에서 수입권공매방식으로, 밤의 경우 현재의 수입권공매방식을 선착순배정방식이나 수입허가제방식으로 바꾸는 것이 바람직한 것으로 분석되었다. 또한, 수입시기를 국내산 성출하시기를 피하여 수입하는 것이 바람직하며, 수입냉동품, 세관검사 및 저가신고에 대한 적절한 수입관리대책도 필요한 것으로 나타났다. The objectives of this study are to analyze the problems of import administration system for minimum market access of chestnut, Korean pine nut and jujube, and suggest its improvement measures. Major findings are as follows : The fill rate of minimum market access for chestnut was very low of about 10% since 1995. The import administration agency of Korean pine nut suffered the loss from abrupt exchange rate change and had weak market control, Therefore it was suggested that Quota Auction System is better than current State Trading System for Korean pine nut, and First-Come First-Served System or Import License System is better than current Quota Auction System for chestnut. And it is desirable to import during the period beyond the main harvesting season for domestic products, and needed to construct the adequate aministration measures for forzed product import, customs examination and low price declaration.
( Seong-rin Lim ) 한국폐기물자원순환학회(구 한국폐기물학회) 2019 ISSE 초록집 Vol.2019 No.-
To commit to the global challenges of climate change and energy security, our society needs to use various renewable energy resources. Among them, a diverse range of combustible wastes are readily utilized because waste-to-energy technology is mature and has been well established. However, waste-to-energy has the potential to incur environmental and human health concerns related with toxic heavy metals in combustible wastes during ashes disposal and recycling as well as waste combustion Thus, this study suggests a practical methodology to screen toxic combustible wastes and to identify priority heavy metals to be targeted for pollution prevention. The methodology is based on the assessment of toxicity potentials (i.e., cancer, non-cancer, and eco-toxicity potentials) from heavy metals in combustible wastes on a per-energy basis. The toxicity potential is quantified by using the heavy metal contents and low heating value (LHV) of a combustible waste and the characterization factors accounting for the fate, exposure, and effect of heavy metals. This study can be used for energy facilities to practically screen less toxic fuels from locally available combustible wastes and to easily select post-treatment processes for the removal of priority heavy metals.
Lim, Seong-Rin,Park, Jong Moon Elsevier 2009 Journal of environmental management Vol.90 No.11
<P><B>Abstract</B></P><P>Life cycle impact assessment (LCIA) is performed to quantitatively evaluate all environmental impacts from products, systems, processes and services. However, LCIA does not always provide valuable information for choosing among alternatives with different specifications, functionalities and lifetimes. The objectives of this study are (1) to propose environmental indicators to evaluate environmental efficiency and value qualitatively and quantitatively on the basis of analogies to financial and economic indicators, and (2) to present the application of the indicators. Incremental evaluation using a reference is employed to obtain the environmental indicators. The environmental efficiency indicators are conceptually based on the ratios of reduced environmental burdens returned to environmental burdens required: environmental return on investment, environmental payback period and environmental internal rate of return. The environmental value indicator is the sum of all reduced and required environmental burdens: i.e., environmental net present value. All the environmental indicators can be used to compare and rank the environmental efficiencies or values of alternatives. The environmental efficiency indicators can be applied to a new environmental labeling. The concept of eco-efficiency labeling is developed by combining the environmental efficiency indicators with financial indicators. A case study is performed to illustrate the necessity and importance of the environmental indicators. These environmental indicators can help easily communicate LCIA results in the field of environmental management.</P>
The detecion of African swine fever virus via hair plucking: An alternative non-invasive approach
Chae-Rin Park(Chae-Rin Park),Tae-Young Suh(Tae-Young Suh),Da-Hye Yi(Da-Hye Yi),Soo-Kyoung Lee(Soo-Kyoung Lee),Seong-Keun Hong(Seong-Keun Hong),Ki-Hyun Cho(Ki-Hyun Cho),Jee-Yong Park(Jee-Yong Park),Yon 한국예방수의학회 2022 한국예방수의학회 학술대회자료집 Vol.2022 No.-
Park, Seong Ji,Lee, Seung Koo,Lim, Chae Rin,Park, Hye Won,Liu, Fang,Kim, Seong-Jin,Kim, Byung-Chul Academic Press 2018 Biochemical and biophysical research communication Vol. No.
<P><B>Abstract</B></P> <P>Heme oxygenase-1 (HO-1) has been implicated in tumor progression, but the underlying molecular mechanisms remain largely unknown. Transforming growth factor-β1 (TGF-β1) exhibits cytostatic and apoptotic effects in hepatocytes and several types of hepatocellular carcinoma (HCC) cell lines, and deregulation of its signaling pathway is linked to hepatic tumorigenesis. In the present study, we observed that HO-1 is expressed at higher levels in HCC tissues than in paired normal tissues. Moreover, TGF-β1-induced cell cycle arrest and up-regulation of cyclin-dependent kinase inhibitors in HCC cell lines were significantly attenuated by overexpression of HO-1 or treatment with tricarbonyldichlororuthenium(II) dimer ([Ru(CO)<SUB>3</SUB>Cl<SUB>2</SUB>]<SUB>2</SUB>, suggesting an inhibitory role of the HO-1/CO axis in TGF-β signaling to growth inhibition in HCC cell lines. Interestingly, we observed that [Ru(CO)<SUB>3</SUB>Cl<SUB>2</SUB>]<SUB>2</SUB> inhibits TGF-β1-induced Smad3-dependent reporter activity without affecting its C-terminus phosphorylation, complex formation with Smad4, and nuclear translocation. Additional experiments revealed that HO-1/CO axis selectively induces phosphorylation of Smad3 at Thr-179 residue in the linker region through activation of extracellular signal-activated kinase (ERK) 1/2. Transfection with a phospho-deficient Smad3 (T179A) mutant or treatment with FR180204, a specific inhibitor for ERK1/2, significantly reversed the inhibitory effects of HO-1 and [Ru(CO)<SUB>3</SUB>Cl<SUB>2</SUB>]<SUB>2</SUB> on cell cycle arrest induced by TGF-β1. These findings for the first time demonstrate that HO-1/CO axis confer resistance of HCC cells to TGF-β growth inhibitory signal by increasing Smad3 phosphorylation at Thr-179 via ERK1/2 pathway.</P> <P><B>Highlights</B></P> <P> <UL> <LI> HO-1/CO axis inhibits TGF-β1-induced growth inhibition in human HCC cell lines. </LI> <LI> HO-1/CO axis inhibits TGF-β1-induced Smad3 activation. </LI> <LI> HO-1/CO axis selectively induces Smad3 phosphorylation at Thr179. </LI> <LI> Smad3 Thr179 phosphorylation mediates the inhibition of TGF-β responses by HO-1. </LI> <LI> ERK1/2 mediates HO-1 or CO-induced Smad3 phosphorylation at Thr179. </LI> </UL> </P>
( Ae-rin Baek ),( Gil Myeong Seong ),( Song-i Lee ),( Won-young Kim ),( Yong Sub Na ),( Jin Hyoung Kim ),( Bo Young Lee ),( Moon Seong Baek ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.0
Purpose High-flow nasal cannula (HFNC) is a useful tool in patients with hypoxic respiratory failure. However, there is a concern for the association between HFNC and delayed intubation or increased mortality. This study aims to investigate that late failure of HFNC is associated with mortality in patients with coronavirus disease 2019 (COVID-19). Method A retrospective multicenter study was conducted at seven university-affiliated hospitals in Korea. We collected the data of hospitalized patients with COVID-19 between February 10, 2020, and February 28, 2021. Failure of HFNC was defined as the need for mechanical ventilation despite HFNC application. According to the time of intubation, HFNC failure was divided into early failure (within 48 hours) and late failure (after 48 hours). The primary outcome was in-hospital mortality. Result During the study period, 157 patients received HFNC, and 133 were eligible. Among them, 70 received mechanical ventilation. Median time from HFNC initiation to intubation of early failure group was 4.1 hours (interquartile range [IQR]: 1.1-13.5 hours), and those of late failure group was 70.9 hours (IQR: 54.4-145.4 hours). Although the ROX index within 24 hours of HFNC initiation had a low tendency in the early failure group than the late failure group, the ROX index before two hours of intubation was significantly lower in the late failure group (5.74 [IQR: 4.58-6.98] vs. 4.80 [IQR: 3.67-5.97], p=0.040, Fig 1). In the multivariable logistic regression analysis, higher CCI (OR 5.38 [95% CI: 1.18-24.56]), higher SOFA score (OR 5.04 [95% CI: 1.34- 18.90]), and late HFNC failure (OR 4.76 [95% CI: 1.12-20.24]) were independent risk factors for in-hospital mortality. Conclusion Late failure of HFNC may be associated with higher mortality in COVID-19 patients with acute respiratory failures.