소아에서 발생한 골수이형성 증후군 2례

홍성진,윤석중,김성우,조형구,오명호,김기혁,이인성 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Myelodysplastic syndrome(MDS) is a group of acquired conditions characterized by progressive bone marrow failure associated with normocellular or hypercellular bone marrow that cannot be attributed to nutritional deficiency, chronic infection, or other chronic systemic illness, and cannot be reversed by the successful treatment of those conditions. Whereas the cases of secondary MDS occur at all ages, primary MDS is essentially a disease of elderly, though no age group is exempt and predomonant in men. The MDS is fundamentally clonal disorders at the level of the haemopoietic totipotent stem cell. Clinically, they are characterized by varing degrees of peripheral cytopenia(s) with morphological and functional abnormalities of blood elements. We have experienced two unrelated pediatric cases, who showed pancytopenia on admission and the characteristic marrow findings of MDS. The first case, a 12 months-old girl, showed increased reticulin with abnormal localization of immature precursor cells(ALIP) in her bone marrow, in addition to dysplastic features such as bi-and multi-nucleation of late normoblasts and internuclear bridging. She also showed 22% of blasts in her bone marrow cells thus classified in the category of RAEB-t after FAB classification. Also found were a chromosomal abnormality namely 46 XX t(14q21q), which was an unusual one. Her family brought her home and, 4 month later, she deceased. The second case, a 12 year-old boy, showed pancytopenia with Pseudo-Pelger-Huet anomaly in neutrophils but no blasts in the peripheral blood. Bone marrow of this case also showed the picture of dyserythropoiesis with binuclearity, internuclear bridging, nuclear fragments, multinuclearity of late normoblasts, in addition to megaloblastoid change in the normoblasts and increased mitosis in granulocytic series. No chromosomal abnormality was found. Classified as RA after FAB classification of MDS. Showed good response to conservative management for anemia for more than one year.

축산분뇨중의 암모니아성 질소 제거

진양오,최성우,김성우,김익성,신남철,박승조 동아대학교 환경문제연구소 1999 硏究報告 Vol.22 No.2

The purpose of thus study were to investigate the proper conditions of struvite formation in synthetic wastewater and then to apply these conditions to effluent of anaerobic digester of livestock wastewater The conditions of struvite formation had been studied by many researchers. But a little conditions were different among them. Especially, according to suspended solid variation in livestock wastewater was investigated by few researchers. In experiment of synthetic wastewater, the proper conditions of struvite formation were pH 105, l50rpm of mixing rate, 10 minutes of reaction time, and 20 minutes of precipitation time. At same time, the ammonia nitrogen removal rates were about 99.7%, 95.5%, and 96% of synthetic wastewater, raw wastewater, and effluent of anaerobic digester of livestock wastewater at molar ratio of 2(Mg):l(N)2(P) respectively. The larger factor of NH₄/SS constant was, the more effective the removal rate of ammonium nitrogen, SS was, but the less effective COD_(cr), and TOC was. By using XRD analysis, the most certain compound in precipitate of synthetic wastewater was struvite.

CMP 폐액의 고액분리에서 응집제의 영향에 관한 연구

홍성호,오석환 대한상하수도학회 2002 상하수도학회지 Vol.16 No.2

A coagulation was applied to separate the solid and liquid from waste CMP generated from the CMP process. Three different coagulants - PACl, MgCl_2 and Ca(OH)^2 was used to find the best coagulant and optimum condition of each coagulant for water and solid recovery. When the solid content was 0.lwt%, the adequate flocculation speed was 10 to 30 rpm for PACl. However, the flocculation speed was not critical for MgCl_2 and Ca(OH)_2 at any dosage. Minimum sedimentation time was 30 minutes to get less than 1NTU of turbidity, the sludge volume was 10 to 15% and 50 to 55% for 0.1wt% and 0.5wt% of waste CMP slurry, respectively. According to the experimental results such as turbidity, zeta potential and heavy metal concentration in the supernatant PACl was the best coagulant for water recovery.

Superconducting MgB2 Wire Drawing Considering Anisotropic Hardening Behavior and Hydrostatic Effect

Young‑Seok Oh,Ho Won Lee,Kook‑Chae Chung,Duck‑Young Hwang,Seong‑Hoon Kang,Jeong Whan Yoon 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.7

Numerical modeling was conducted to investigate the deformation behavior of powder mixture during multi-pass drawingprocesses for multi-filamentary MgB2wire. A modified Drucker-Prager Cap (DPC) model with an elliptical cap surface usingthe new material characterization method was developed to capture the anisotropic hardening behavior and hydrostatic effectof the powder mixture. A number of uniaxial die compaction, cold isostatic pressing, diametrical compression, and uniaxialcompression tests were conducted using different powder densities to characterize the modified DPC model. A commercialfinite element software ABAQUS with a user subroutine was used to simulate the drawing of the MgB2wire. The densityand area fraction of the powder mixture during the wire-drawing process were verified with experimental results. The differencein packing density at the inner and outer filaments of the MgB2wire was successfully captured by simulation. Inaddition, the effect of the initial packing density on the superconducting properties of MgB2wire was numerically studied. It is shown that the increase in the superconducting area, which results from a high initial packing density, should be moreeffective compared to the increase in the grain connectivity in enhancing the critical current properties for the MgB2wirewhen the final packing density is saturated after a number of drawing processes.

성남지역의 안악골 골절에 관한 임상적 연구

김일규,손성준,오성섭 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.4

This is a clinical and retrospective study who sustained a total of 306 maxillofacial bone fracture and who were treated in our department between 1990-1994. This results were obtained as follows : 1. The ratio of men to women was 3.2 : 1. 2. The age frequency was the highest in the third decade(35%). That of man was the highest in the third decade but that of women in the fourth decade. 3. In respect of incidence, the number of patients has not been increased year after year. There were the highest frequency in September and the lowest frequency in January. 4. The most frequent cause of facial bone fracture was fall down(40.2%), traffic accident(28.1%), fist blow(20.9%), industrial accident(6.2%) and others in order. 5. The most common location of facial bone fracture was mandible(69%), maxillar with zygoma and zygoma in order of frequency. 6. The age frequency of mandible was the third decade(36.5%), the fourth decade(23.2%) and the fourth decade(22.2%) and the fifth decade(15.6%) in order. 7. In respect of incidence of associated injuries, the ratio of absence to presence was 0.7 : 1. 8. In 306 patients of facial bone fracture, the frequency of associated injuries was laceration, extrimities, chest in order.

Algal bioassay 에 의한 조류생장 제한영양염류 결정

오희목(Hee Mock Oh),이석준(Seog June Lee),김성빈(Seong Bin Kim),박미경(Mi Kyung Park),윤병대(Byung Dae Yoon),김도한(Do Han Kim) 한국하천호수학회 1998 생태와 환경 Vol.31 No.2

Determination of Limiting Nutrient for Algal Growth by Algal Bioassay. Oh, Hee-Mock, Seog June Lee, Seong-Bin Kim, Mi- Kyung Park, Byung-Dae Yoon and Do-Han Kim (Environmental Microbiology Research Unit, Korea Research Institute of Bioscience and Biotechnology, Taejon 305-333, Korea and Water Resources Research Institute, Korea Water Resources Corporation, Taejon 305-390, Korea) Water quaiity and algal growth potential (AGP) using Microcystis aeruginosa were investigated from April to September 1997 in Daechung Reservoir. Secchi disk transparency was 1.1 m in August. Chlorophyll-a concentrations were higher than 10㎍/l at all samples. Total phosphorus concentration was in a range of 0.020∼0.027mg/l which is at the approximate value of 0.03 mg/l, the general critical level of eutrophication. These results indicate that Daechung Reservoir is in an eutrophic state except some temporary times and restricted sites. Phosphorus uptake rate of M. aeruginosa was higher in the water from the epilimnion than in the hypolimnion and also higher under light condition than under dark condition. Therefore, phosphorus uptake rate appears to depend on cellular phosphorous content and light condition, a meaning of endergonic process. Phosphorus was the most frequently limiting nutrient: phosphorus was limiting algal gowth in April and May, nitrogen, phosphorus and trace elements were the limiting factors for algae in August, and trace elements in September. If a fast growing alga, M, aeruginosa, is used as a test organism for assaying AGP, in vivo fluorescence instead of dry weight can be measured for algal biomass and incubation period can be reduced from traditional 14 days to 7 days.

OK-432(Picibanilⓡ)와 외과적 절제술을 이용한 선천성 림프관종의 치험례

김일규,이성호,오성섭,최진호,오남식,김왕식,임영일,양동환 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.3

Lymphangiomas are relatively rare benign tumors of the lymphatic system, characterized by congenital lymphatic malformation such as anastomosis or obstuction of the lymphatic channels. There are most frequently diagnosed in children younger than 3years. In contrast to that of the hemangioma, the sex distribution of the lymphangioma is nearly evenly divided. The head and neck lymphangioma represents about 70∼75% of all lymphangiomas, and they are difficult to manage. Spontaneous regression is rare, and rapid intermittent enlargement occurs secondary to infection or trauma. Enlargement may cause serious sequelae such as airway obstruction, feeding difficulties, and cosmetic problems. Treatments previously used for lymphangiomas include surgical excision and intralesional injection of sclerosants. Problems associated with surgical excision include the risk of cosmetically unacceptable scarring and the risk of damage to surrounding vital stricture and the high risk of incomplete excision. The sclerosants previously used have numerous other local and systemic side effects. This report describes a case that was successfully treated using OK-432 as a new sclerosant drug and secondary surgical excision for congential cavenous lymphangioma extensively enlarged to tongue, mouth floor and submandibular region.

헤어리베치 신품종 조생종 콜드그린과 중만생종 청파의 생육특성 및 수량성

신정남(Chung Nam Shin),고기환(Ki Hwan Ko),김종탁(Jong Tak Kim),이종경(Joung Kyong Lee),서성(Sung Seo),성병렬(Byung Ryul Seong),최기준(Gi Jun Choi),김종덕(Jong Duk Kim),오명곤(Myung Gon Oh) 한국초지조사료학회 2007 한국초지조사료학회지 Vol.27 No.4

본 시험의 목적은 대구 경북에 자생하는 헤어리베치로 다수성 조생품종과 중만생품종을 개발하기 위하여 수행하였다. 경북 성주와 경남 사천에서 1998년부터 2006년까지 자료수집 및 순화, 생육이 왕성한 조생 및 중만생계통선발, 상호교잡의 단순순환선발법으로 조생종인 콜드그린과 중만생종인 청파를 육성하였다. 육성종자는 2004년부터 2006년까지 경북성주와 경남사천에서 생육특성과 수량을 평가하였다. 줄기의 털은 콜드그린과 청파는 있었으나, 헤이메이커프러스와 라티고는 없었다. 잎의 모양은 콜드그린은 엽폭이 넓은 장타원형이고, 청파, 헤이메이커프러스, 라티고는 좁은 장타원형이었다. 꽃색은 콜드그린은 자주색이고 청파는 보라색이었다. 내한성은 성주에서 콜드그린, 청파, 라티고가 헤이메이커프러스 보다 높았으며 사천에서는 차이가 적었다. 개화기는 콜드그린과 헤이메이커프러스가 조생종으로 유사했고 중만생종인 청파는 라티고 보다 다소 빨랐다. 성주에서 건물수량은 콜드그린이 다른 품종 보다 높았으며 청파와 헤이메이커프러스는 라티고 보다 높았다(P<0.05). 2005년 사천에서는 콜드그린과 헤이메이커프러스는 다른 품종보다 높았으며, 청파는 라티고 보다 높았다(P<0.05). 베치의 조단백질 함량은 높고 ADF의 함량은 낮았다. The objective of this research was to develop a high yielding, early and medium-late flowering new hairy vetch(Vicia villosa Roth) varieties derived from an accession in Korea. Most vigorous early and medium-late flowering hairy vetch lines were selected and crossed by open pollination and their seeds were bulked and plants were reselected at Seongju in the Keongbuk and at Sacheon in the Keongnam. A performance trial was conducted to evaluate agronomic characteristics, forage quality and dry matter(DM) yield of new hairy vetch early-maturing 'Cold green' and medium-late maturing variety 'Cheong pa' at Seongju and Sacheon. 'Cold green' and 'Cheong pa' are hair but 'Haymaker plus' and 'Latigo' are nearly hairless. 'Cold green' has purple flowers while 'Cheong pa' has violet. The cold tolerance of 'Cold green,' 'Cheong pa' and 'Latigo' was higher than 'Haymaker plus' at Seong-ju, Keongbuk province, in inland region but there were a little differences at Sacheon, Keongnam province in southern coast region. Fifty percent-flowering dates of 'Cold green' and 'Haymaker plus' had earlier than others and 'Cheong pa' was earlier than 'Latigo'. The DM yield of 'Cold green' was higher than that of others, but 'Cheong pa' and 'Haymaker plus' had higher than 'Latigo' at Seong-ju(P<0.05). In Sacheon, The DM yield of 'Cold green' and 'Haymaker plus' was higher than others and 'Cheong pa' had higher than 'Latigo'.

公務員의 責任限界에 관한 考察 : 國家에 대한 理解와 價置判斷의 制限性 the Understanding about State and Limiting of Value Judgement

吳成浩 연세대학교 대학원 1989 원우론집 Vol.16 No.1

ABSTRACT This article is on the ethical responsibility of Public employee with which he confrons performing his duties with the understanding about state. At first, It is need to define the character of stare, the source of state power and slope of its resopnsibility, but very difficult. These are various according to writers or eras. Nevertheless, we can and some common points among them. The concept of state are specified as that of status society - the medieval feudal and the absolute monarchy society, that of pluralistic society and that of class society. First, state is the system of order. Every resource and goods are distributed and possessed in this order. The power of state is for maintaining this system. Second, the essence of this system and the location and the limit of state power are expressed as a law. Third, the ethics of public employee who executes state power is based on the order system expressed as a law. From the above character, we can find the scope of public employee's - in the pluralistic society-responsibility. Public employee is expected to be a public servant, a member of public organization a professional dealing with complex social problems. As a public servant, he has duties to pursuit public interest. Bur how can he know what public interest is? He can know it not by his own judgement, but through the obedience ot the will of goverment which is constituted by the people. And he has to obey the law which is established by the representative institution. of course, public employee's discretion is much limited but the scope of responsibility becomes clear. As a member public organization, public employee has to obey the command from higher position. Appleby explained that hierarchy is format structure and instrument of responsibility. Public employee can be responsible to the will of people when he performs his duties according to superior's legal command. As a professional public employee, he has duties using and informing the knowledge appropriately. And, when he uses his knowledge. some limits are posed to his value judgement from the perspective of whole secieyt.

국내 식물자원 추출물에 대한 항산화 활성 검색

오성준,백남인,김해영 경희대학교 생명자원과학연구원 1999 硏究論文集 Vol.20 No.-

We investigated the antioxidative activity to obtain novel antioxidants from plant resources in Korea. Three hundreds species of plants were collected and screened with DPPH (1.1-diphenyl-2-picryl hydrazyl) radical test. From this work. 10 species of plants showed a significant antioxidative activity.