소아에서 발생한 골수이형성 증후군 2례

홍성진,윤석중,김성우,조형구,오명호,김기혁,이인성 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Myelodysplastic syndrome(MDS) is a group of acquired conditions characterized by progressive bone marrow failure associated with normocellular or hypercellular bone marrow that cannot be attributed to nutritional deficiency, chronic infection, or other chronic systemic illness, and cannot be reversed by the successful treatment of those conditions. Whereas the cases of secondary MDS occur at all ages, primary MDS is essentially a disease of elderly, though no age group is exempt and predomonant in men. The MDS is fundamentally clonal disorders at the level of the haemopoietic totipotent stem cell. Clinically, they are characterized by varing degrees of peripheral cytopenia(s) with morphological and functional abnormalities of blood elements. We have experienced two unrelated pediatric cases, who showed pancytopenia on admission and the characteristic marrow findings of MDS. The first case, a 12 months-old girl, showed increased reticulin with abnormal localization of immature precursor cells(ALIP) in her bone marrow, in addition to dysplastic features such as bi-and multi-nucleation of late normoblasts and internuclear bridging. She also showed 22% of blasts in her bone marrow cells thus classified in the category of RAEB-t after FAB classification. Also found were a chromosomal abnormality namely 46 XX t(14q21q), which was an unusual one. Her family brought her home and, 4 month later, she deceased. The second case, a 12 year-old boy, showed pancytopenia with Pseudo-Pelger-Huet anomaly in neutrophils but no blasts in the peripheral blood. Bone marrow of this case also showed the picture of dyserythropoiesis with binuclearity, internuclear bridging, nuclear fragments, multinuclearity of late normoblasts, in addition to megaloblastoid change in the normoblasts and increased mitosis in granulocytic series. No chromosomal abnormality was found. Classified as RA after FAB classification of MDS. Showed good response to conservative management for anemia for more than one year.

Effective Combination of Agrobacterium tumefaciens Strains and Ti Plasmids for the Construction of Plant Vector System

Kim, Mi Suk,Park, Jeong Ku,Eum, Jin Seong,Sim, Woong Seop 한국식물학회 1996 Journal of Plant Biology Vol.39 No.3

The purpose of this study is to obtain the most efficient combination of Agrobacterium tumefaciens strains and Ti plasmids for the construction of dicotyledonous plant vector system. Ti plasmid-curing A. tumefaciens A136 and KU12C3 were transformed with four kinds of Ti plasmids, pTiBo542, pTiA6, pTiKU12 and pTiAch5, respectively. The stems of 28 species of dicotyledonous plants were then inoculated with these transformants and examined for crown gall formation. The different combination of A. tumefaciens strains and Ti plasmids showed quite a difference in terms of the crown gall formation. Agrobacterium strains A136 and KU12C3 have a same plant host range in case that both strains barbour the same kind of Ti plasmid, pTiBo542 or pTiAch5. However, the above-mentioned both strains have quite different host range in the event of containing the same Ti plasmid, pTiKU12 or pTiA6. In case that KU12C3 contains pTiA6 or pTiKU12, this strain has a wider plant host range than A136. The plant host range of pTiBo542 is the widest, followed by pTiA6, pTiKU12 and pTiAch5. Twelve plants among 28 tested plants are not transformed by any virulent Agrobacterium strains used in this study. In conclusion, A. tumefaciens KU12C3 and A136 harboring pTiBo542 showed the widest host range for transforming dicotyledonous plants. Also, it was acertained that the host range of Ti plasmids is affected by chromosomal level.

가창학습시 계명창과 가사창의 상호 우선학습의 장단점에 대한 고찰 : Centered on the 6th Grade Students

김성복,양순구 晋州敎育大學校 初等敎育硏究所 1993 初等敎育硏究 Vol.3 No.-

햄릿 공연을 위한 무대의상 디자인 (Ⅰ) : 관객을 통한 인물이미지 분석 The Analysis of Actor Image by Spectator

김순구,황성원 한국의류산업학회 2004 한국의류산업학회지 Vol.6 No.1

This study is done to assist in the limit of stage dress design research considering the sense of the times and the sympathy of spectators for actual stage. For the base research, to visualize the image which the spectators are feeling from Shakespeare's Hamlet, the evaluators had to analyze the whole image and color tone of the figures. First of all, 2 clothing for Hamlet, Gertrude and Ophelia had to be designed, and following conclusion has drawn. Hamlet A corresponds with passive looks which is a combination of loneliness, sadness and the unstable mental state of not adapting to and hiding from the reality. Hamlet B has more of matured looks which make Hamlet more free and comfortable from life and death as he overcame a crisis of death. Gertrude A corresponds with the image of coming right out of the funeral of late king. Gertrude B shows more of her sadness as she hears of her son Hamlet's despair and resentment and her maternal return degradation which is a special situations emphasizing her unstable and dizzy image. Ophelia A shows her usual and normal looks of a livelihood and femininity. She congratulates the wedding and coronation, and falls in love with Ham-let which shows a lot of her girlish image. Ophelia B shows dismantled rationality and violated virginity which is a very complex and unstable state showing a completely different image. Based on the above research. It was proposed their clothing through the next study of the characters, and personally make them for 2003 Yeonheedan Street Group's performance Hamlet.

Lutembacher 증후군 환자 증례 보고

김성범,서정주,곽철훈,김상민,이보라,민선경,황은구,김용인,조욱현,최석구 인제대학교 2008 仁濟醫學 Vol.29 No.-

Lutembacher's syndrome is rare combination of mitral stenosis (MS) and atrial septal defect (ASD). The hemodynamic interplay between the MS and ASD leads to wide variation of clinical presentation. Here we describe a 43-year-old female with Lutembacher's syndrome and tricuspid regurgitation with pulmonary hypertension, who underwent direct closure of ASD and tricuspid valvuloplasty successfully. We also reviewed other literatures in an effort to increase awareness of this condition.

율무 종자의 크기 및 溫度에 따른 幼苗의 生長 特性

윤성탁,김봉구 단국대학교 1998 論文集 Vol.32 No.-

This study was conducted to investigate seedling characteristics of Job's tears according to the seed size and different germination temperatures in order to find out the method to improve the seedling vigor and uniform establishment of Job's tears(Coix lachryma-jobi L.) in the field. The results obtained were summerized as follows. 1. In the 100 grain weight of seeds of two varieties. Yunchoon 9 ho was 14.2g, which was 2.4g more higher than that of Yulmoo 1 ho. 2. In the percentage of emergence of two varieties. Yunchoon 9 ho was 81.4% that was 7.4% more higher than that of Yulmoo 1 ho and small seed size was 6% more higher than large seed between seed sizes. 3. In the percentages of germination under different temperatures, 25℃ plot was 39.7%, which was lowest and 30℃ and 35℃ plots showed the same percentage of 96.7%. Accordingly it is judged that from 30℃ to 35℃ is advisable to ensure uniform emergence. 4. Days from seeding to emergence was not shown different between two varieties, but it was shown significantly different among seed size and temperature treated. Days from seeding to emergence of large seed size was 6.7 days which is 0.6 day shorter than that of 7.1 days of small seed. Among temperatures treated, 25℃, 30℃ and 35℃ were respectively and it was observed that 35℃ plot showed the shortest in days from seeding to emergence. 5. Dry weight of plant at 20 days after seeding among seed sizes and temperatures was shown statistically difference. Large seed was 38.0㎎ that is 8㎎ higher than 30㎎ of small seed. Dry weight due to the germinating temperatures of 25℃, 30℃ and 35℃, 35℃ plot showed 42.3㎎, which is highest compared with other two temperatures of 30.5㎎, and 29.0㎎ respectively. 6. Chemical composition of seeds in the content of moisture, ash and crude fat were not significantly different, but content of crude protein was significantly different.

라텍스개질 콘크리트의 열팽창 특성 분석

최성용,이주형,임홍범,윤경구 강원대학교 산업기술연구소 2003 産業技術硏究 Vol.23 No.A

The properties of mechanics and durability of LMC have been performed actively. However. little studies on analysis and properties of thermal expansion has been on the temperature variation. Especially. the low of bonding strength and tensile cracking are caused by difference of thermal expansion between LMC and the substrate concrete Therefore, this study focused on effect of thermal expansion behavior and properties of LMC according to temperature variation. To identify the property of thermal expansion of LMC. tests of modulus of thermal expansion were carried out at 28 days after casting specimen. subjected to temperature variation between 10℃ and 60℃ The results of this study showed the modulus of elastic of LMC was similar to that of ordinary portland concrete(OPC) It means that stresses caused by difference of modulus of elastic did not occur on interface between LMC and existing concrete The modulus of thermal expansion of LMC had a little smaller than that of OPC The modulus of thermal expansion of polymer modified concrete is generally larger than OPC. but the result of this test IS disagree with the fact. which may be due to the humidity evaporation difference and aggregate properties

콘크리트 포장의 플라이애쉬 재활용 방안연구

정영화,최성용,윤경구,용석응,김태경 강원대학교 석재복합신소재제품연구센터 1998 석재연 논문집 Vol.3 No.-

한국 대부분의 고속도로는 콘크리트로 포장되고 있으며, 플라이애쉬를 포장용 콘크리트에서 재활용하면 콘크리트의 성능을 향상시킴과 동시에 경제적 이익과 환경보호에 큰 기여를 할 것이다. 본 연구에서는 플라이애쉬를 포장 콘크리트에 재활용하고자, 플라이애쉬 치환율, 물-시멘트비, 굵은골재 최대치수를 주요실험 변수로 하여 이들이 플라이애쉬를 혼입한 포장용 콘크리트의 역학적 특성에 미치는 영향을 살피기 위해서 실험하여 통계처리 분석하였다. 이러한 분석결과를 바탕으로 포장 콘크리트의 적정배합을 제시하였으며 결과는 다음과 같다. 플라이애쉬를 혼입한 포장콘크리트의 휨강도에 영향을 미치는 인자는 플라이애쉬 치환율이 가장 큰 것으로 나타났으며, 다음으로 굵은골재 최대치수와 물-시멘트비 순으로 영향을 미친다. 또한, 플라이애쉬 치환율과 굵은골재 최대치수의 상관관계가 가장 큰 것을 알 수 있었다. 목표압축강도를 목표 휨강도의 6배로 선택하여 적정구간을 결정하였으나, 적정배합구간이 목표압축강도에 의해서 결정되었다. 이는 플라이애쉬의 작은 수화물이 공극을 효과적으로 채움으로써 휨강도의 증진에 크게 기여하기 때문으로 판단된다. 고속도로 포장에 적용할 수 있는 32mm의 굵은골재 최대치수와 45%의 물-시멘트비를 사용하는 목표 휨강도 45kg/㎠의 적정배합에서는 5.0%까지 플라이애쉬를 치환 가능하고, 50kg/㎠의 적정배합에서는 2.5%까지 치환 가능하다. 공항 포장에 적용할 수 있는 40mm의 굵은골재 최대치수와 37%의 물-시멘트비를 사용하는 목표 휨강도 45kg/㎠의 적정배합에서는 4.5%까지 플라이애쉬를 치환 가능하고, 50kg/㎠의 적정배합에서는 2.0%까지 치환 가능하다. The most of highway in Korea have been paved by concrete since last ten years. The recycling of fly ash in pavement concrete may result in economics, the improvement of concrete quality and the reservation of environment. This paper focused on the series of experiment and statistics analysis with experimental variables such as fly ash substitute ratio, water-cement ratio and maximum size of coarse aggregate in order to investigate the feasibility of recycling of fly ash in pavement concrete, to see the strength characteristics and t propose the optimum mix design based on previous results. The results of experiments and analysis were follows; The fly ash substitute ratio affected most seriously to the flexural strength of concrete among main variables, followed by maximum size of coarse aggregate and water-cement ratio. The interaction between fly ash substitute ratio and coarse aggregate size was the biggest. The optimum mix design was determined by target compressive, which was selected as 6 times of flexural strength. This indicated that the small hydrate of fly ash in concrete filled in effectively and resulted in the enhancement of flexural strength. the optimum mix design for highway pavement concrete with 32mm of maximum size of coarse aggregate and 45% of W/C can incorporate up to 5.0% and 2.5% of fly-ash at 45 kg/cm² and 50 kg/cm² of target flexural strength, respectively. The optimum mix design for airport pavement concrete with 40mm of maximum size of coarse aggregate and 37% of W/C can incorporate up to 4.5% and 2.0% of fly ash at 45 kg/cm² and 50 kg/cm² of target flexural strength, respectively.

소아에서 나타난 비구개관낭의 치험례

모정희,정현구,조태식,김효석,박성규,이난영 조선대학교 구강생물학연구소 2002 口腔生物學硏究 Vol.26 No.2

The nasopalatine duct cyst is the most common non-odontogenic cyst in the oral area and is thought to be originated from the epithelial remnants of the nasopalatine duct. The nasopalatine duct cyst have been mentioned to be an overall incidence of 1.7-11.9% of all jaw cyst. More males than females are affected by that. It could occur all around the age, and especially in their 40th and 60th it happens the most and in childhood it is very rare. Proper treatment for nasopalatine duct cyst is enucleation. In the case of very large cysts, it is likely to be a risk of naso-oral or antral-oral fistulas or of devitalization of teeth, marsupialization is indicated. The purpose of case report is that a nasopalatine duct cyst in is very rare in childhood. A 9-year-old boy was referred to the chosun university pedodontics clinic that this child who has anterior palatal swelling is in routine check. The size of the cyst was so big that the marsupialization was committed and obturator was put. This patient is on the continuous observation. we treated the nasopalatine duct cyst with obturator.

X-cut LiNbO_3 광도파로 제작 및 패턴 특성

정운조,김성,박계춘 국립7개대학공동논문집간행위원회 2001 공업기술연구 Vol.1 No.-

The optical near field patterns, propagation loss and mode sizes of x-cut Ti:LiNbO_3 optical waveguide which was fabricated by Ti-diffusion varying with Ti strip thickness in wet oxygen atmosphere were investigated and tested at optical wavelength 1550㎚. As Ti thickness increased from 760A˚, the insertion loss of waveguide was decreased. But at Ti thickness 1500A˚, mode sizes are widely broadened. The Ti thickness of below 1100A˚ and above 1500A˚ showed negative effects to propagation loss and fiber coupling. The best Ti thickness for fabricating low propagation loss and good fiber coupling was inferred to be between 1100A˚-1500A˚ in our conditions. And for Ti thickness 1150A˚, its propagation loss, horizontal/vertical mode sizes were measured 1.61㏈/㎝, 11.9/8.9㎛ for TM, 0.22㏈/㎝, 12.0/9.1㎛ for TE respectively.