KI-180과 KI-188 칼슘조성물이 어린쥐의 성장발육에 미치는 영향

박승만(Seung-Man Park),성기승(Ki-Seung Seong),이종석(Jong-Seok Lee),이옥환(Ok-Hwan Lee),한찬규(Chan-Kyu Han) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.3

본 연구에서는 KI-188 칼슘과 KI-180 조성물이 성장발육에 미치는 효과를 조사하였다. 시험기간중 KI-188 칼슘과 KI-180 식이군이 대조군 보다 성장률과 평균 식이섭취량은 증가하였다. 체장은 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 평균 3.55 mm 더 길었고, 등뼈길이는 KI-180 식이군이 대조군 보다 통계적인 차이는 없었지만 0.5 mm 더 길었다. 대퇴골 무게는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 무거웠으며, 대퇴골길이는 대조군에 비해 각각 평균 0.89, 1.09 mm 더 길었다. 혈당, 총콜레스테롤 및 중성지방 농도는 차이가 없었고, 칼슘농도는 KI-188 칼슘과 KI-180 식이군 보다 대조군이 유의하게 높았다. 백혈구와 혈소판수는 차이가 없었고, 적혈구, 혈색소 및 헤마토크릿치는 대조군이 KI-188 칼슘과 KI-180 식이군 보다 통계적으로 높았다. ALP활성은 KI-180 식이군이 대조군 보다 통계적으로 높았고, osteocalcin농도는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 유의하게 높았다. 혈청 testosterone 농도는 KI-188 칼슘과 KI-180 식이군과 대조군 간에 차이가 없었다. IGF-1과 IGFBP-3 농도는 KI-180 조성물이 대조군 보다 각각 20%, 11% 정도 유의하게 더 높았다. 이상의 결과를 검토할 때 KI-188 칼슘과 KI-180 조성물은 어린쥐의 성장과 골격의 발달을 촉진시키고, 성장호르몬의 분비능을 양적으로 유도하여 전반적인 성장발육에 유효한 작용이 있는 것으로 사료된다. Herbs have active components that promote the growth rate of both animals and human. The KI-180 and KI-188 calcium food formulae contain Acanthopanacis cortex, Bombysis corpus and hoelen, seaweed calcium, chlorella extract, spirulina, colostrum powder, and other natural and functional components. We evaluated the growth-promoting effects of these formulae by analyzing the weight, femur and backbone, alkaline phosphatase, osteocalcin, testosterone, insulin-like growth factor (IGF)-1, and IGF binding protein-3 (IGFBP-3) of growing rats. Growing rats administered with KI-180 and KI-188 calcium showed the increase of body weight, body length, and femur weight and length of growing rats. In addition, administration of KI-180 and KI-188 calcium increased the alkaline phosphatase activity, the levels of osteocalcin and the growth hormones IGF-1 and IGFBP-3 of growing rats. The impact of KI-180 and KI-188 calcium on the physical development of growing rats suggests that the incorporation of these food formulae in the diets of growing children may promote the physical development.

직장 카르시노이드 종양에서 Ki-67 발현의 예후적 중요성

홍수민 ( Su Min Hong ),김유선 ( You Sun Kim ),문정섭 ( Jung Seop Moon ),김진남 ( Jin Nam Kim ),오명기 ( Myoung Ki Oh ),권선옥 ( Sun Ok Kwon ),정성연 ( Seong Yeon Jeong ),홍성우 ( Seong Woo Hong ),강윤경 ( Yun Kyung Kang ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.2

Background/Aims: Rectal carcinoid tumors can be resected with endoscopy, and it is important to assess their prognostic factors. We evaluated the potential of Ki-67 expression as a prognostic factor in rectal carcinoid tumors. Methods: We retrospectively reviewed the medical records of 37 patients with rectal carcinoid tumors who got endoscopic resection from January 2001 to January 2011 at Inje University Seoul Paik Hospital. We analyzed their endoscopic and histologic findings, Ki-67 expression, clinical outcome, and prognosis. Results: The mean age (±SD) of the patients was 56.3±10.7 years, and the male : female ratio was 3.6:1. The mean tumor size was 0.5±0.4 cm, 33 patients showed grade 1 tumors (89.2%) and the average Ki-67 expression was 0.7±1.2%. Thirty five patients underwent endoscopic mucosal resection, and two required endoscopic submucosal dissection. Eight patients had positive margins after resection, but no cases of lymphovascular invasion were identified. The median follow-up duration was 21.4±25.4 months, and no recurrences were observed. Conclusions: In low grade rectal carcinoid tumors which are lack of central depression on colonoscopy, the expression of a molecular marker of malignant potential, Ki-67, was low. Therefore, endoscopic resection seemed to be a safe and effective treatment for these tumors.

怨歌의 硏究

金成基 한국고시가문학회 2003 한국시가문화연구 Vol.0 No.12

This is a study on < Won-ga >, a native song of our country. This song was written by Shin Chung. He wrote this song resenting King Hyo-seong who broke the vow. This song describes Shin who later became a monk and built a temple named Dan-sok-sa. The title of the story is Shin-chung-gwe-gwan and Won-ga belongs to it. The former part of this song is the background story of Won-ga and the latter part deals with Lee Soon. In other words, the song was written by Shin Chung and Dan-sok-sa was established by Lee Soon. King Gyeong-duk described in Sam-guk-sa-gi (historical record about three kingdom) was presented as an evidence. There is a suggestion that Shin-chung-gwe-gwan is not involved in only one person, Shin Chung. This study intended to illuminate the suggestion. And it dealt with the content of Won-ga, and the form and outline of the song.

개에서 발생한 수컷 가성 반음양 1례

이기찬,손정민,윤기영,최호정,박성준,이영원,정성목,신상태,조종기 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2006 動物醫科學硏究誌 Vol.14 No.-

In this report, we present a case of the male pseudohermaphrodite in a beagle dog. The animal was subjected for examination due to enlargement of clitoris that was shown as reddish finger-like structure protruding from the vulva. Visual examination of the internal genitalia revealed that the animal possessed both testes and uterus. Based on the findings of physical examination and exploratory laparotomy, it was tentatively diagnosed as male pseudohermaphrodite. Internal genitalia and enlarged clitoris were removed for the prevention of pyometra and Sertoli cell tumor.

개에서 발생한 기관 허탈의 진단과 관리

이새미,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A 11-year-old Yorkshire terrier anesthetized for computed tomography. The dog showed cyanosis and syncope during postanesthetic recovery, therefore drug administrated parenterally. Goose-honking was noticed after full recovery. As a result of survey radiography and fluoroscopy, grade 4 tracheal collapse was diagnosed. Prescription for the dog was oral administration of hydrocodone 0.22 mg/kg. theophylline 20 mg/kg, prednisone 0.5 mg/kg, amoxicillin 22 mg/kg and chlorpheniramine 2 mg/kg twice a day for 3 days. A 10-year-old Pomeranian was diagnosed as grade 2 traceal collapse at the local animal hospital 2 years before being referred to the veterinary teaching hospital of Chungnam National University. On physical examination, goose-honking, coughing and intermittent open-mouth breathing. Tracheal narrowing was observed on survey einradiography and fluoroscopy. Oral administration of theophylline 13 mg/kg, enrofloxacin 5 mg/kg, chlropheniramine 0.5 mg/kg twice a day was prescribed for 2 weeks.

개의 아토피 피부염에 대한 Leflunomide의 임상적 적용 1례

홍은지,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A Shih-tzu(8-year-old, castrated male) was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with the history of relapsing pruritus, recurrent dermatitis. On the physical examination, generalized erythema, otitis externa, alopecia and lichenification were observed. Using Favrot's criteria for diagnishing atopic dermatitis, 7 criteria were satisfied out of 8 criteria. After treatment for infection, intradermal skin test was performed(positive allergen : Df, Dp). And then immunotherapy was performed, but clinical signs were not getting better. Next treatment of glucocorticoid shown little improvement of clinical signs, and adverse effect(diarrhea) was shown after cyclosporine application. So application of leflunomide which is used for human atopic dermatitis treatment in some case was planned. After 6 months of application of leflunomide, clinical signs were decreased gradually.

개에서 발생한 이혈종의 임상적 관리

이우철,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A 14-year-old male pomeranian was present with swollen left ear. The swelling occurred from base to apex of pinna. Otitis externa persisted for two years. Hematological and serum biochemistry values were not remarkable. The surgery treatment was the most appropriate method among indwelling drain, surgical, and steroid treatment in the aural hematoma because the dog was very sensitive to touching pinna and the size of aural hematoma. Longitudinal incision was applied after general anesthesia. Cefovecin was injected to prevent secondary infection. The outcome of surgery was good. There was no evidence of recurrence for one year.

개에서 발생한 양파 섭취에 의한 하인즈 소체 용혈성 빈혈 증례

이미선,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A 10 month-old Yorkshire Terrier was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with the history of lethargy, bile pigment in urine and anorexia. Blood smear showed Heinz body, polychromatocytosis, schistocytosis, anisocytosis, which were the results from the oxidative injury. Hematology demonstrated a moderate anemia(PCV 22.4%, reference rage 35-55%), which was regeneration based on the degree of RPI (4.03, reference rage > 1). Serum biochemistry demonstrated mild elevation in total bilrubin, and mild decrease in total protein and albumin concentration. A diagnosis of Heinz body hemolytic anemia secondary to onion ingestion was made and treated with fluid therapy, oxygen and antioxidant drugs. The dog recovered without any complication.

일가족에 발생한 Microsporum canis 감염증

서무규,성열오,윤기상,하경임 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

Microsporum (M.)canis 감염은 애완용으로 기르는 고양이나 개가 주된 감염원이며 두부 백선, 안면백선 및 체부 백선 등의 피부질환을 일으킨다. 특히 M. canis 가족감염예는 M. canis 감염증중 비교적 드물다. 저자들은 전형적인 임상 및 균학적 양상을 보인 고양이로부터 감염된 M. canis 가족예를 경험하고 문헌고찰과 함께 보고한다. Microsporum canis Infections Occurring in a Family Departments of Dermatology & Clinical Pathology, College of Medicine, Dongguk University Moo Kyu Suh M.D., Yeol Oh Sung M.D., Ki Seong Yoon M.D., Gyoung Yim Ha M.D." We report a case of Microsporum (M.) canis infections occurring in a family. The mother, a son and a daughter had multiple, wen defined, round, scaly erythematous patches on the scalp & face, face & trunk, and face & chest respectively. Culture from skin lesion of patients and an infected kitten on Sabouraud dextrose agar showed M. canis. After 15 days to one month administration of itraconazole, the lesins healed leaving a slight hypopigmentation.

헤어리베치 신품종 조생종 콜드그린과 중만생종 청파의 생육특성 및 수량성

신정남(Chung Nam Shin),고기환(Ki Hwan Ko),김종탁(Jong Tak Kim),이종경(Joung Kyong Lee),서성(Sung Seo),성병렬(Byung Ryul Seong),최기준(Gi Jun Choi),김종덕(Jong Duk Kim),오명곤(Myung Gon Oh) 한국초지조사료학회 2007 한국초지조사료학회지 Vol.27 No.4

본 시험의 목적은 대구 경북에 자생하는 헤어리베치로 다수성 조생품종과 중만생품종을 개발하기 위하여 수행하였다. 경북 성주와 경남 사천에서 1998년부터 2006년까지 자료수집 및 순화, 생육이 왕성한 조생 및 중만생계통선발, 상호교잡의 단순순환선발법으로 조생종인 콜드그린과 중만생종인 청파를 육성하였다. 육성종자는 2004년부터 2006년까지 경북성주와 경남사천에서 생육특성과 수량을 평가하였다. 줄기의 털은 콜드그린과 청파는 있었으나, 헤이메이커프러스와 라티고는 없었다. 잎의 모양은 콜드그린은 엽폭이 넓은 장타원형이고, 청파, 헤이메이커프러스, 라티고는 좁은 장타원형이었다. 꽃색은 콜드그린은 자주색이고 청파는 보라색이었다. 내한성은 성주에서 콜드그린, 청파, 라티고가 헤이메이커프러스 보다 높았으며 사천에서는 차이가 적었다. 개화기는 콜드그린과 헤이메이커프러스가 조생종으로 유사했고 중만생종인 청파는 라티고 보다 다소 빨랐다. 성주에서 건물수량은 콜드그린이 다른 품종 보다 높았으며 청파와 헤이메이커프러스는 라티고 보다 높았다(P<0.05). 2005년 사천에서는 콜드그린과 헤이메이커프러스는 다른 품종보다 높았으며, 청파는 라티고 보다 높았다(P<0.05). 베치의 조단백질 함량은 높고 ADF의 함량은 낮았다. The objective of this research was to develop a high yielding, early and medium-late flowering new hairy vetch(Vicia villosa Roth) varieties derived from an accession in Korea. Most vigorous early and medium-late flowering hairy vetch lines were selected and crossed by open pollination and their seeds were bulked and plants were reselected at Seongju in the Keongbuk and at Sacheon in the Keongnam. A performance trial was conducted to evaluate agronomic characteristics, forage quality and dry matter(DM) yield of new hairy vetch early-maturing 'Cold green' and medium-late maturing variety 'Cheong pa' at Seongju and Sacheon. 'Cold green' and 'Cheong pa' are hair but 'Haymaker plus' and 'Latigo' are nearly hairless. 'Cold green' has purple flowers while 'Cheong pa' has violet. The cold tolerance of 'Cold green,' 'Cheong pa' and 'Latigo' was higher than 'Haymaker plus' at Seong-ju, Keongbuk province, in inland region but there were a little differences at Sacheon, Keongnam province in southern coast region. Fifty percent-flowering dates of 'Cold green' and 'Haymaker plus' had earlier than others and 'Cheong pa' was earlier than 'Latigo'. The DM yield of 'Cold green' was higher than that of others, but 'Cheong pa' and 'Haymaker plus' had higher than 'Latigo' at Seong-ju(P<0.05). In Sacheon, The DM yield of 'Cold green' and 'Haymaker plus' was higher than others and 'Cheong pa' had higher than 'Latigo'.