우리나라 지역 직업성질환 감시체계의 현황과 전망

임종한,장성실,김성아,문재동,채창호,홍윤철,김수영,김진석,김영욱,한상환,이혜숙,원종욱,송동빈,하은희,강성규 대한산업의학회 2001 대한직업환경의학회지 Vol.13 No.2

기존의 특수건강진단과 작업환경측정을 통한 직업병 관리가 진폐증, 소음성난청 등의 소수 특정질환에 국한되고 실제 직업병 발생 규모 파악이나 신종 직업병의 발견에 한계를 보인다는 사실은 산업의학전문가들 사이에서도 공감을 이루고 있다. 미국과 영국 등에서의 직업성질환 감시체계에 대한 경험은 우리 나라의 직업성질환 감시체계 구축에도 새로운 자극제가 되면서, 1998년이후 인천, 대전, 여천, 구미, 부울경 지역에서 지역 직업성질환감시체계를 산업보건관리의 중요한 시스템으로 구축하려는 노력이 확산되고 있다. 새로이 구축되어지는 이들 지역 직업성질환 감시체계는 감시하고자 하는 대상질환, 활용 가능한 인적자원 및 자료원, 지역 의료체계의 특수성 등에 따라서 목적과 방법을 달리하면서 독특한 형태로 발전을 하고 있다. 각 지역단위 감시체계들이 그 상황에 맞게 독특한 목적과 전략들을 발전 시키면서도, 향후 발전할 국가적인 차원의 직업성질환 감시체계 구축을 위하여 직업성질환 감시의 기본 전략 등을 공유하는 등의 노력이 필요하다. 환례 정의 및 기본적인 등록 서식의 공유, 직업성질환 감시 자료원의 발굴, 공동의 정보 네트워크 및 직업성질환 감시 데이터베이스 구축 등 직업성질환 감시활동을 지원하기 위한 여러 기초 인프라 구축에 힘을 모아야 할 것이다. 우리 나라에서 직업성질환 감시체계를 성공적으로 구축하기 위해서는 수집된 자료의 질 관리를 위한 직업성질환 감시의 원칙 제정과 감시 전략의 공유 등이 필요하며, 전국적인 직업성질환 감시체계의 하부구조라고 할 수 있는 지역감시체계의 기초 토대 마련과 강화작업이 절실하게 필요하다.

Algal bioassay 에 의한 조류생장 제한영양염류 결정

오희목(Hee Mock Oh),이석준(Seog June Lee),김성빈(Seong Bin Kim),박미경(Mi Kyung Park),윤병대(Byung Dae Yoon),김도한(Do Han Kim) 한국하천호수학회 1998 생태와 환경 Vol.31 No.2

Determination of Limiting Nutrient for Algal Growth by Algal Bioassay. Oh, Hee-Mock, Seog June Lee, Seong-Bin Kim, Mi- Kyung Park, Byung-Dae Yoon and Do-Han Kim (Environmental Microbiology Research Unit, Korea Research Institute of Bioscience and Biotechnology, Taejon 305-333, Korea and Water Resources Research Institute, Korea Water Resources Corporation, Taejon 305-390, Korea) Water quaiity and algal growth potential (AGP) using Microcystis aeruginosa were investigated from April to September 1997 in Daechung Reservoir. Secchi disk transparency was 1.1 m in August. Chlorophyll-a concentrations were higher than 10㎍/l at all samples. Total phosphorus concentration was in a range of 0.020∼0.027mg/l which is at the approximate value of 0.03 mg/l, the general critical level of eutrophication. These results indicate that Daechung Reservoir is in an eutrophic state except some temporary times and restricted sites. Phosphorus uptake rate of M. aeruginosa was higher in the water from the epilimnion than in the hypolimnion and also higher under light condition than under dark condition. Therefore, phosphorus uptake rate appears to depend on cellular phosphorous content and light condition, a meaning of endergonic process. Phosphorus was the most frequently limiting nutrient: phosphorus was limiting algal gowth in April and May, nitrogen, phosphorus and trace elements were the limiting factors for algae in August, and trace elements in September. If a fast growing alga, M, aeruginosa, is used as a test organism for assaying AGP, in vivo fluorescence instead of dry weight can be measured for algal biomass and incubation period can be reduced from traditional 14 days to 7 days.

골수강내 경골 절골 지침자를 이용한 슬관절 전치환술

빈성일,최준원,남태석 대한슬관절학회 2003 대한슬관절학회지 Vol.15 No.1

목적 : 골수강내 경골 절골 지침자를 사용하여 시행하여 슬관절 전치환술에서 경골 절골각 및 하지 정열의 정확도를 알아보고자 하였다. 대상 및 방법 : 1998년 11월부터 2001년 8월까지 골수강내 경골 절골 지침자를 이용하여 시행한 슬관절 전치환술 343예 중 술후 1년 이내에 기립상 전하지 방사선 촬영을 시행한 160예를 대상으로 하였다. 술후 방사선 사진상 경골의 해부학적 축과 경골 삽입물이 이루는 각도 및 대퇴골의 해부학적 축과 경골의 해부학적 축이 이루는 각도를 계측하였다. 결과 : 경골의 해부학적 축과 경골 삽입물이 이루는 각도는 평균 89.5°, 범위는 84°~94°였고, 90°±2°에 133예(83.1%)가 해당되었고, 그 중 66예(41.3%)는 90°였다. 대퇴골의 해부학적 축과 경골의 해부학적 축이 이루는 각도는 평균 5.6°였고, 범위는 0°~11°였다. 결론 : 슬관절 전치환술에서 경골 절골의 지침자로, 골수강내 지침자를 정확한 술식대로 사용할 경우 만족할 만한 경골 절골각 및 하지 정열을 얻을 것으로 사료된다. Purpose: To evaluate the tibia osteotome angle and whole leg alignment in total knee replacement arthroplasty using intramedullary tibia guide. Methods & Materials : Amongst 343 cases of TKA using an intramedullary tibial cutting guide from November 1998 to August 2001, 160 cases who took a standing whole leg AP simple roentgenography within 1 year were selected. Post-operatively, the angle formed by the tibial anatomical axis anbd tibial component, along with the angle with the angle formed between the femoral anatomical axis and tibial anatomical axis and tibial anatomical axis were measured. Results : The average angle between the tibial anatomical axis and tibial component was 89.5°(84°~94°), 133 cases (83.1%) were within the range of 90°±2° and amongst these 66 cases(41.3%) were 90°. The average angle formed between the femoral anatomical axis and tibial anatomical axis was 5.6°(0°~11°). Conclusion : When used properly, and intramedullary tibial cutting guide in TKA result in satisfactory tibial osteotome angle and whole leg alignment in TKA.

페놀분해 효모 Candida tropicalis PW-51의 분리 및 분해특성

김성빈,김치경,김희식,이창호,신기선,권시석,윤병대,오희목 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.6

본 연구는 페놀과 포름알데히드를 포함하는 페놀계수지 산업폐수의 생물학적 처리에 이용할 목적으로 포름알데히드의 존재하에서 페놀분해능이 우수한 효모를 sludge로부터 분리하여, 형태적 및 생리 생화학적 특징을 조사하여 Candida tropicalis PW-51로 동정하였다. 회분식 배양에서 C. tropicalis PW-51의 페놀 분해한계는 2,000 mg/ℓ이며, 58시간내에 완전히 분해하였다. C. tropicalis PW-51은 초기접종량이 9×10 exp (6) cells/㎖, 배양온도는 30℃, pH는 7.0에서 페놀 분해효율이 높았으며, 500~2,000 mg/ℓ의 페놀농도에서 조사된 페놀에 대한 평균 분해율은 페놀 1,000 mg/ℓ에서 45.5 mg/ℓ/h 가장 높았다. C. tropicalis PW-51의 페놀분해시 catechol 1,2-dioxygenase의 활성이 크게증가하므로 ortho-path-way에 의해 페놀을 분해하는 것으로 판단되었다. 따라서, C. tropicalis PW-51는 페놀계 수지 산업폐수의 생물학적 처리에 효과적으로 이용될 수 있는 균주로 사료된다. For the biological treatment of phenolic resin wastewater containing phenol and formaldehyde, a phenol-degrading yeast was isolated from the papermill sludge, and then identified as Candida tropicalis PW-51 according to morphological, physiological and biochemical properties. The strain was able to degrade high phenol concentrations up to 2,000 mg/ℓ within 58 hours in batch cultures. Phenol-degrading efficiency by the strain was maximum at the culture conditions of a final concentration of 9×10 exp (6) cells/㎖ 30℃ and pH 7.0. The mean degradation rate of phenol was highest at 45.5 mg/ℓ/h in 1,000 mg/ℓ phenol from 500 mg/ℓ to 2,000 mg/ℓ phenol. Because the enzyme activity of catechol 1,2-dioxygenase increased in the course of degradation of phenol, it seems that this strain degrades phenol via the ortho-cleavage of benzene ring. The isolate C. tropicalis PW-51 could be effectively used for the biological treatment of phenolic resin wastewater.

液體噴流의 分裂길이에 관한 硏究

任成彬 忠州大學校 1998 한국교통대학교 논문집 Vol.33 No.1

The study of liquid jet disintegration process is one of fundamentals to the atomization and sprays and is important in the research of spray characteristics. This study has the aim at supplying fundamental data of liquid jet disintegration process. Three test nozzles used in this experiment have diameters of 4, 6, 8mm, respectively and their orifice length to diameter ratio is 50. The measurement of liquid jet breakup length was conducted with the method of image processing.

운동기간에 따른 혈중지단백대사 및 비만호르몬의 변화

홍성찬,함용기,김영빈,박병근,정동혁,이정윤,권성택 圓光大學校 附設 體力科學硏究所 2003 體力科學硏究 Vol.26 No.2

The purpose of this study is to elucidate the effects of regular swimming exercise on blood lipoprotein metabolism and leptin. In this study, swimming(HRmax 50-75%, 60min/day, 5day/week) was performed and 18 were participated for study during 16 weeks. They were divided into two groups, one group as experimental group(n=9) and the other as control group(n=9). A measured factors were TC, TG, HDL-C, LDL-C and leptin.. All data were expressed as mean± standard deviation by using spss package program(win 9.0), one way anova and independent t-test was used to analyze the difference of exercise duration(0week, 8week, 12week, 16week) between groups. For all statistics performed statistical significance was set at p<.05. After exercise intervention, TC, TG, HDL-C, LDL-C and leptin were found to have more significant effects in the experimental group than control group. This results indicated regular swimming exercise training is beneficial to prevent and treat cardiovascular disease and obesity.

의료용 조합자극기(HAPPY DREAM HM-206DB) 적용이 동결견 환자의 통증과 관절가동범위에 미치는 영향

홍성찬,김영빈,박병근,김유성,이성진,정동혁 원광대학교 체력과학연구소 2008 體力科學硏究 Vol.30 No.1

The purpose of this study is to find out the effectiveness of the HAPPY DREAM HM-206DB applied to the patients with Frozen Shoulder by measuring, assessing and analyzing the changes in pain and range of motion(ROM). Surveyed from Mar. 2007 to Dec. 2007 were 10 patients suffering from Frozen Shoulder. After HAPPY DREAM HM-206DB, the pain were measured and analyzed by means of MPQWL, VAS-I and VAS-U, while ROM was measured and analyzed by using Goniometer. The major findings from this study are as follows; 1. There was significant decrease in the MPQWL after HAPPY DREAM HM-206DB applied(p<.001). 2. There was significant decrease in the VAS-I(intensity of pain) after HAPPY DREAM HM-206DB applied(p<.001). 3. There was significant decrease in the VAS-U(unpleasantness of pain) after HAPPY DREAM HM-206DB applied(p<.001). 4. There appeared, however, significant increase in ROM(abduction, external and internal rotation) after HAPPY DREAM HM-206DB applied(p<.001). From the above outcomes, it was revealed that HAPPY DREAM HM-206DB application has proven to reduce the pains, exercising huge influence to increase ROM. It is, therefore, suggested to continue and expand the study on the cure of Frozen Shoulder and to motivate patients, rehabilitation specialists, and health management specialists etc. to consider HAPPY DREAM HM-206DB application as safest and most efficient pain remedy.

유산소성 운동이 혈중지질 및 체지방률에 미치는 영향

홍성찬,김영빈,윤영복,박병근,김유성 圓光大學校 附設 體力科學硏究所 2007 體力科學硏究 Vol.29 No.-

This study is aimed at investigating the effects of aerobic exercise of female college students on blood lipids and body fat percentage. Twelve female students were selected for this study and each 6 of them were alloted into the control group and experiment group. The experiment group underwent jogging for 12 weeks and its effects on blood lipids and body fat percentage were measured at the 4th, 8th and final week of the jogging program. The outcomes of the experiment could be summarized as follows: 1. As for HDL-C due to jogging, the experiment group showed an eminent increase with statistical significance(p<.05). 2. In case of LDL-C following jogging, there was a great amount of decrease in the experiment group after the exercise with statistical significance(p<.05). In sum, it is revealed from the present study that the prescribed magnitude and length of exercise can be of help for HDL-C and LDL-C that have been recognized as indicators for diseases of adult people.

Frozen Shoulder에 있어서 마사지의 치료적 접근

홍성찬,김영빈,박병근,정동혁,이정윤,이동헌 圓光大學校 附設 體力科學硏究所 2003 體力科學硏究 Vol.26 No.1

Painful stiffness of the shoulder is an ill-defined clinical entity that is difficult to assess and delicate to treat. The nomenclature used is broad and includes terms such as frozen shoulder, adhesive capsulitis, focal algodystrophy, stiff shoulder, contracted shoulder, and others. Apart from its idiopathic form, the disease can be initiated by trauma, infection, tumour, radiation, systemic and local metabolic disturbances. Pathoanatomically, the common denominator is an inflammatory vascular proliferation followed by thickening, scarring, and retraction of the joint capsule. The inflammatory process often starts at the rotator interval and may extend to the subacromial space. Clinical diagnosis is based on history and physical examination. Generally the onset of pain precedes the perception of a reduced range of motion by weeks or months. In early stages of the disease, the inflammatory type of pain dominates, i.e., the patient's main complaint ist pain at night. In the later stage, range of motion gradually decreases. Patients do not often complain about reduced motion, probably because of its slow onset. The purpose of this study is to find out the effectiveness of the massage applied to the patients with Frozen Shoulder by measuring, assessing and analyzing the changes in intensity and unpleasantness of pain and range of motion(ROM) before and after massage. Surveyed from Jan. 2001 to December 2002 were 104 patients suffering from Frozen Shoulder. In the therapeutic massage program, such methods as Effleurage, Petrissage and Deep transverse friction were selected as they are among traditional massage treatments frequently used for joints with pain and restricted ROM. Effleurage and Petrissage were applied for 20 minutes in total before and after Deep Transverse Friction. After massage program, the intensity and unpleasantness of pain were measured and analyzed by means of VAS(visual analogue scale)-I and VAS-U, while ROM was measured and analyzed by using Goniometer. The major findings from this study are as follows; 1. The surveyed patients range from 28 to 75 in age, with highest numbers of 44(42.31%) registered in the fifties and next ones of 24(23.08%) in the forties. Divided by sex, 59 are women and 45 are men totalling 104 with average age of 51.4. 2. There was significant decrease in the intensity of pain and unpleasantness of pain after massage(p<.05). 3. There appeared, however, significant increase in ROM after massage(p<.05). 4. From the analysis into chronological changes in ROM before and after massage with ANOVA, it became evident that the longer the period of treatment was, the higher the ROM increases drastically, while significant difference was shown in Abduction and in External and Internal Rotation(p<.05). Summed up, it can be generally concluded that massage is an effective treatment to rid the patients with Frozen Shoulder of pains safely and promptly. This study was conducted to determine more accurate impact of massage. From the above outcomes, it was revealed that massage has proven to reduce the pains, exercising huge influence to increase ROM. It is, therefore, suggested to continue and expand the study on the cure of Frozen Shoulder and to motivate patients, orthopedists, physiatrists, physiotherapists, and sports massagists etc. to consider massage as safest and most efficient pain remedy.

흡연에 의한 급성 호산구성 폐렴 2예

박종빈,김학렬,주현준,유태양,신성남,신정현,송정섭,황기은,김소영,양세훈,정은택 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

최근 흡연을 시작한 젊은 성언에서 급성 호산구성 폐렴의 발생에 대한 증례가 보고되고 있다. 급성 호산구성 폐렴은 대개 발열을 동반하기 때문에 초기에는 감염성 폐렴으로 잘못 진단, 치료되는 경우가 많다. 아직 정확한 병태 생리 및 조직학적 소견은 밝혀져 있지 않지만 병력 청취 및 임상 양상, 방사선 소견의 관찰을 통해 급성 호산구성 폐렴을 의심하고, 진단을 위해 기관지 폐포 세척액 검사를 시행한다면 좀 더 쉽게 진단 내릴 수 있을 것이다. 본 저자들은 최근 처음 시작한 흡연에 의해 발생한 급성 호산구성 폐렴을 진단하고, 스테로이드를 투여하여 성공적으로 치료한 환자 2예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Acute eosinophilic pneumonia(AEP) is characterized by acute febrile respiratory illness associated with diffuse pulmonary infiltration and pulmonary eosinophilia. The specific etiology for acute eosinophilic pneumonia is elusive. By some investigators, cigarette smoking is suggested as a causative substance which can cause AEP. In recent, the authors experienced two cases of AEP following cigarette smoking. Both cases had characteristic features including age around 20 years, new onset smoking before occurance of AEP, diffuse infiltration on chest radiography, pulmonary eosinophilia based on bronchoalveolar lavage and acute improvement after steroid therapy. These clinical features are resemble with previous smoking induced AEP case reports. Base on these clinical features, cigarette smoking associated AEP could be diagnosed more easily.