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      • KCI등재후보

        기관내관 소독방법 개선에 따른 간호업무 시간단축 및 비용 절감 효과

        이행선,김해리나,김은숙,김보람,성선숙 한국의료QA학회 2008 한국의료질향상학회지 Vol.14 No.1

        Background: The purposeof innercannula is to protect the upperair wayand permitair to pass freely, in addition, to provideendotrachealsuction, artificial respiration and to maintain adequate oxygensaturation. The tubeneeds to be sterilizedformaintenanceand cleannessof air wayand forprevention of bronchospasm. However, it has been reportedthat there is no guideline forsterilization and manyhospitalsconducttheirown sterilization methods, forexample, oncea day(13's generalhospital), three timesa day(TheCatholic University of Korea STMary's hospital) or evenno cleansing. Consequently, the QI team of our hospitalsuggested the SOP(standard operatingprocedure) of sterilization and evaluate cost and timeeffect in nursing. Method: 1) Benchmarking of 13's neurosurgery departmentof generalhospital in Seoul 2) Investigation of test recordsof sputumculture from patientswith intubation for tracheotomy 3) Checkof resultsof 02 Sat. monitoring to confirm of maintainingopenedair way Result : 1) Improvement of process: decrease of excess sterilization of inner cannula (from 3 timesa day to oncea day) 2) Costeffects: saving over10 million wonper oneyear 3) Providing better nursing: time effects (30 mina day) permit to conductmorenursing activities Conclusion: Itcan get Costand timeeffectsin nursing withimproved sterilization methodof innercannula It needs to do researchon improvement of the monthly exchangeprotocol of outercannula and providesupportingdata forthe properexchangeschedule. The resultof additionalmicroorganism detection frompatients withnewprocessneeds to be evaluated furthermore.

      • KCI등재후보

        띄어쓰기에 관한 몇 가지 문제

        이선웅 국어국문학회 2003 국어국문학 Vol.- No.134

        The primary aim of this paper is shomng various examples of word-spacing that have not been noticed carefully. As Han-geul is Mitten in syllable basically, the problems of word-spacing is out of question in pragmatic standpoint. Therefore, to solve the pragmatic problems of word-spacing we should widen pennitted limits concerning orthographical rules. In this paper, in addition to pointing out shortcomings in orthographical rules on word-spacing I argue that 'N+N', 'V-eo(어) V‘ constructions and 'the preceding nouns + the dependent nouns' should be able to be Mitten in one group. About the construction of 'N+V, I argue that the semantic independency of N should be regarded as a criterion for judging whether a form in question is a word or not and that we should study functional verbs more deeply in order to make the problem of word-spacing easy.

      • KCI등재

        학습장애가 있는 아동과 없는 아동의 귀인성향과 학교생활적응

        김이선,김윤옥 한국특수아동학회 2003 특수아동교육연구 Vol.5 No.1

        본 연구는 학습장애아동과 일반아동의 귀인성향과 학교 생활 적응도를 비교하고 그 상관관계를 밝히기 위한 연구이다. 연구방법은 질문지를 통한 조사방법을 택하였으며, 귀인성향 검사지, 학교 생활적응 검사지를 대전광역시 및 충청남도에 소재한 특수학급이 있는 초등학교에 배포하여 4, 5, 6학년 학습장애아동 및 일반아동 206명을 대상으로 하여 조사를 실시하였다. 연구의 결과, 학습자애아동과 일반아동의 귀인성향은 상이였다. 학습장애아동은 외적 귀인성향이 강한 반면, 일반아동을 내적 귀인성향이 강하였다. 그리고 학습장애아동이 일반아동보다 학교생활 적응 점수가 낮게 나타났고 학습장애 아동과 일반아동 각각의 귀인성향과 학교 생활 적응은 정적 상관을 나타내었다. 그러나 학습장애 아동과 일반아동의 귀인성향과 학교 생활 적응의 상관의 차이는 유의미하게 나타나지 않았다. The purpose of this study was to compare the attribution tendency and school life adjustment between students with and without learning disabilities (LD). The methods of the study inventory included an attribution tendency and survey of school life adjustment. This study employed 206 LD and normal students of the fourth, fifth and sixth graders from elementary schools is Daejeon and Chung-nam province. The results of this research are as follows. First, the LD group presented external attribution patterns and normal students showed internal attribution patterns. Second, the LD group had low score of the school life adjustment than their counterpart did. Third, students' attribution tendency appeared high correlation with school life adjustment. Forth, it is not significant the difference of a correlation between LD and normal students on attribution tendency and school life adjustment. The authors also discussed that it is necessary to study the difference between the grade and gender toward attribution tendency.

      • KCI등재

        동시형광 분광광도법에 의한 대기 시료 중의 다환방향족 탄화수소(PAHs)의 분석

        유광식,정선이,정지영 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.1

        Determination of some PAHs in ambient air at Ulsan have been carried out by collection of the components into n-hexane followed by synchronous spectrofluorimetric technique. 10 PAHs, such as acenaphthene (Ace), anthracene (Anth), benz[a]anthracene (BaA), benzo[b]fluoranthene (BbFt), benzo[k]fluoranthene (BkFt) benzo [a]pyrene (BaP), chrysene (Chry), phenanthrene (Phen), fluoranthene (Ft), perlyrene (Per), and pyrene (Pyr) in air samples were able to determine separately by synchronous spectrofluorimetry. Calibration curves for those components were linear for the concentration range of 0.2∼166 ppb PAHs with the correlation factor of 0.9985∼0.9999. The predominant contribution was phenanthrene which was included 36.9∼85.1% to the overall level of the 10 PAHs in some areas, Also benzo[a]pyrene which was known to carcinogenicity was detected from 6.4 to 55.8 ng/㎥, benzo[a]anthracene of some areas was contained from 21.9∼153 ng/㎥,

      • DNA-Transfection을 위한 양이온성 리포좀에 포함되는 Phytosphingosine 유도체의 개발

        남궁성건,박선이 서울여자대학교 자연과학연구소 2001 자연과학연구논문집 Vol.13 No.-

        본 연구에서 합성한 TMPㆍI를 함유하는 양이온성 리포좀(TMPㆍI : DOPE = 1 : 1(무게비))으로 in vitro 계에서 유전자 전달 실험을 수행한 결과, L/D 비가 증가할수록 유전자 전달 정도가향상되었고 TMPㆍI는 리포좀 종류에 따라 유전자 전달 정도의 차이를 나타냈는데 SUV 보다 MLV일 때 그 효율이 1 5배 더 증가하였다. DOPE/phytoS(1 : 1 무게비)로 구성된 대조 리포좀의 유전자 전달 효율은 L/D 비가 20에서도3% 정도에 불과한데 비하여 phytos의 아민기에트리메틸레이션한 TMPㆍI를 함유하는 양이온성 리포좀은 11%로 유전자 전달 효율을 3 ~4배 정도 증가시킴을 확인할 수 있었다. 또한 기초적인 생물학적 테스트를 통하여 TMPㆍI를 포함하는 양이온성 리포좀은 TMS를 포함하는 리포좀보다 훨씬 뛰어난 암 전이 억제 효파 및 성장 억제 기능도 나타냄을 알 수 있었다. N,N,N-Trimethylphytosphingosinium iodide (TMPㆍI), a derivative of phytosphingosine(PhytoS), contained in cationic liposome was used to examine its DNA transfection efficiency in BHK cell line in vitro. The result in DNA transfection assay showed that DOPE/TMP liposome was more effective than the control group, DOPE/PhytoS. Unlike conventional liposomes, the liposome comprising TMPㆍI exhibited a high DNA transfection efficiency and it will be very useful tool in developing the delivery system of gene with antitumor activity.

      • KCI등재

        半夏瀉心湯이 CCl4 로 유도된 간중독 흰쥐에 미치는 영향

        朱旺錫,朴賢俊,尹炳局,鄭成伊,朴宣東 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2

        The purpose of this study is to observe the effect of Banhasasimtang on serum reaction in CCI₄ treated rats. In this study the experimental rats divided five group(Normal, Control, Sample A, Sample B and Sample C group) Under the same condition Normal group was fed basal diet and water, Control group was injected carbon tetrachloride(CCI₄ 0.5㎖/㎏) and basal diet for 2 weeks, Sample A group was injected carbon tetrachloride(CCI₄0.5㎖/㎏) and fed the Bahasasimtang extract(10㎖/㎏) for 2 weeks, Sample A group was injected carbon tetrachloride(CCI₄ 0.5㎖/㎏) and fed the Banhasasimtang extract(10㎖/㎏) for 2 weeks, Sample B group was fed the Banhasasimtang extract(10㎖/㎏) for 2 weeks and injected carbon tetrachloride(CCI₄ 0.5㎖/㎏), Sample C group was fed the Banhasasimtang extract(10㎖/㎏) for 2 weeks. The change of GOT, GPT, γ-GPT, ALP, LDH activity and Bilirubin level in blood serum. The obtained results are summarized as follows : 1. In the change of GOT GPT contents, as compared with control group, sample group was significantly decreased. 2. In the change of γ-GPT contents, as compared wth control group, sample group was significantly decreased. 3. In the change of ALP contents, as compared with control group, sample group was significantly decreased. 4. In the change of LDP contents, as compared with control group, sample group was significantly decreased. 5. In the change of Bilirubin contents, as compared with control group, sample group was significantly decreased.

      • KCI등재

        黃連湯이 CCl4로 유도된 간중독 흰쥐에 미치는 영향

        高元島,朴賢俊,尹炳局,鄭成伊,朴宣東 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2

        The purpose of this study is to observe the effects of Hwanglyuntang on serum reactions of CCI₄ treated rats. In this study the experimental rats were divided five groups(Normal, Control, Sample A, Sample B and Sample C). Under the same condition Normal group was fed basal diet and water, the Control group was injected with carbon tetrachloride(CCI₄, 0.5㎖/㎏) and fed a basal diet for 2 weeks, the Sample A group was injected with carbon tetrachloride(CCI₄, 0.5㎖/㎏) and fed the Hwanglyuntang extract(10㎖/㎏) for 2 weeks, the Sample B group was fed the Hwanglyuntang extract(10㎖/㎏) for 2 weeks and injected with carbon tetrachloride(CCI₄, 0.5㎖/㎏), the Sample C group was fed on the Hwanglyuntang extract(10㎖/㎏) for 2 weeks. The change in GOT, GPT, γ-GPT, ALP, LDH activity and Bilirubin level in blood serum were preasured. The obtained results are summarized as follows : It was found that GOT, GPT, γ-GPT, ALP LDH activity and Bilirubin levels in the blood serum of the sample groups, as compared with control group, sample group was significantly decreased.

      • SCOPUSKCI등재

        Quality Characteristics and Quantification of Acetaldehyde and Methanol in Apple Wine Fermentation by Various Pre-Treatments of Mash

        Seon Yi Won,Jae Soon Seo,Han Sub Kwak,Youngseung Lee,Misook Kim,Hyoung-Seok Shim,Yoonhwa Jeong 한국식품영양과학회 2015 Preventive Nutrition and Food Science Vol.20 No.4

        The objective of this study was to compare the effects of adding lactic acid and pectinase, and chaptalization for the quality of apple wine and the production of hazardous compounds (methanol and acetaldehyde). The pH of all of the samples was below 4; therefore, mash seemed to be fermented without any issue. Total acidity was the highest in sample A due to lactic acid addition. Pre-treated groups (samples B, C, and D) showed higher total acidities than that of the control (P<0.05). Pre-treatments might influence the production of organic acids in apple wines. The control and pectinase added sample (sample B) had the lowest alcohol contents. Adding lactic acid produced more alcohol, and chaptalized samples produced more alcohol due to the addition of sugar. Adding pectinase with and without chaptalization was not effective for producing more alcohol. The control sample had significantly higher acetaldehyde content (2.39 mg/L) than the other samples (1.00∼2.07 mg/L); therefore, pre-treatments for apple wine fermentation produced a lower amount of acetaldehyde. Among the pre-treated samples, samples C and D showed the lowest acetaldehyde content of 1.00 mg/L and 1.16 mg/L, respectively. On the other hand, a significantly higher amount of methanol was generated for sample A (1.03 mg/L) and sample D (1.22 mg/L) than that of the control (0.82 mg/L) (P<0.05). Adding lactic acid or chaptalization was effective in reducing methanol and acetaldehyde in apple wines.

      • SCISCIESCOPUS

        Triassic mafic and intermediate magmatism associated with continental collision between the North and South China Cratons in the Korean Peninsula

        Yi, Sang-Bong,Oh, Chang Whan,Lee, Seung-Yeol,Choi, Seon-Gyu,Kim, Taesung,Yi, Keewook Elsevier 2016 Lithos Vol.246 No.-

        <P><B>Abstract</B></P> <P>Triassic coeval mafic and intermediate magmatism occurred in the area suggested to be the southern margin of the North China Craton (NCC) in the Gyeonggi Massif (GM) of the Korean Peninsula. This study investigates aspects of the mafic and intermediate magmatism using SHRIMP zircon ages and whole-rock chemical and isotopic Sr–Nd data. The mafic and intermediate rocks intruded into a basement paragneiss in three areas (Yangpyeong, Odesan and Yangyang) within the GM at ca. 230Ma. The paragneiss was metamorphosed in both the Paleoproterozoic and Triassic. Gabbros (hornblende gabbro and pyroxene–mica gabbro) from the study areas exhibit strong light REE (LREE) enrichment relative to chondrite (La<SUB>N</SUB>/Yb<SUB>N</SUB> =11.1–30.6) and a high LILE/HFSE pattern, Ta–Nb–P–Ti troughs and positive Ba–K–Pb–Sr spikes on the N-MORB-normalized multi-element variation diagram. These features are typical characteristics of arc-related gabbros. The gabbros also show strongly enriched initial isotopic compositions (<SUP>87</SUP>Sr/<SUP>86</SUP>Sr<SUB>(i)</SUB> =0.7100–0.7137; ε<SUB>Nd</SUB>(t)=−13.1 to −19.7). The coeval intermediate intrusive rocks also exhibit whole-rock chemical and isotopic features (<SUP>87</SUP>Sr/<SUP>86</SUP>Sr<SUB>(i)</SUB> =0.7099–0.7143; ε<SUB>Nd</SUB>(t)=−10.8 to −18.6) similar to those of the gabbros. The mafic and intermediate intrusive rocks plot in the within-plate and/or post-collisional fields on tectonic discrimination diagrams. These data indicate that the mafic and intermediate magmatism in the study areas occurred during the Triassic post-collisional relaxation period via partial melting of sub-continental lithospheric mantle (SCLM) that was enriched in a subduction environment prior to (or during) the Permo-Triassic continental collision between the NCC and the South China Craton (SCC). The highly enriched mantle signatures revealed by the gabbros from the study areas are matched to the enriched features identified in Cretaceous mafic igneous rocks (ca. 130Ma) on the southern margin of the NCC. Thus, this study suggests that the lithospheric mantle beneath the Yangpyeong, Odesan and Yangyang areas are comparable to the SCLM of the NCC southern margin. The highly enriched nature of mafic and intermediate rocks from the study areas indicates that their source is the SCLM that was metasomatized by Permian to early Triassic subduction–continental collision processes.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Mafic and intermediate magmatism may have occurred during post-collisional setting. </LI> <LI> The magma source of these rocks appears to be the enriched sub-continental lithospheric mantle (SCLM). </LI> <LI> This lithospheric mantle is comparable to the SCLM of the southern margin of the North China Craton. </LI> </UL> </P>

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