수용성 키틴이 백서 창상치유에 미치는 영향

강장석,조용남,정상훈,유 결,임진수,권 호,조용우,고석원 大韓成形外科學會 2001 Archives of Plastic Surgery Vol.28 No.1

석청(Mad-honey) 복용 후 유발된 부정맥 1예

김용철,김남호,김승환,최준호,박은미,이상재,이은미,유남진,윤경호,오석규,정진원 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

석청에 포함된 grayanotoxin에 의해 독성 작용이 나올 수 있으며, 이러한 독성 작용은 일반적으로 24시간 이내 저절로 회복된다. 최근에 본 저자들은 석청 복용 후 발생한 심실빈맥을 경험하였기에 보고하는 바이다. 49세 남자가 호흡곤란으로 내원하였으며, 내원당시 분당 40회 정도의 동성 서맥이 관찰되었고, 수액을 투여하던 중 심실 빈맥이 발생하였다. 항부정맥제를 투여 후 정상 동율동으로 전환되었으며, 특별한 이상 없이 4일 후 퇴원하였다. Mad-honey intoxication caused by the consumption of honey producted from the nectar of rhododendrons. The grayanotoxins cause the intoxication. The toxic effects of mad-honey poisoning are rarely fatal and generally last for no more than 24 hours. We experienced one case, a 49 years-old man who presented with dyspnea after ingestion of mad-honey. He showed marked sinus bradycardia with < 40 beats per minute on admission. The cardiac rhythm was changed to ventricular tachycardia immediately. These features resolved completely in 24 hours with continuous infusion of amiodarone(600 mg per day) and fluids. We report the case of intoxication of mad-honey as a presentation of fatal cardiac arrhythmia.

합기도 수련생의 수련 지속 요인에 관한 연구

김의영,남승현,김석일,정용우,정천규 龍仁大學校 武道硏究所 1998 武道硏究所誌 Vol.9 No.1

This study investigated participants who have taken part in Hapkido continuously, in view of age, carrier in exercise, and gender and then analysed how these factors affect continuous participation in Hapkido. 1) The significant factors which enable the participants to continue Hapkido were revealed as health/physical fitness(71.67%), enjoyment / interrest (58.13%), self-protetio / guard(48.28%), phychological benefits(20.94%) 2) The factors of continuing Hapkido were different in ages, which showed significant differences in phychological benefits, skill fulfilment / challenge, accomplishment / position, charm, recreational activity. The response represented specifically in one or two areas in case of younger participants. The more aged, it showed relatively even distribution to the various responses due to the broaden span of thoughts. 3) The factors of continuing Hapkido were different in carrier, which showed significant differences in self-protection / grard, skill fulfillment / challenge, accomplishment/ position in different experiences in exercise. By the time of reaching first phase and second phase, it is thought to show the psychological effect of continuing exercise unconsciously in various areas. 4) The factors of continuing Hapkido were not different in gender, which implicated the fact that the overall attitude and thoughts on Hapkido of female participants and male participants are similar.

방광암조직 acid deoxyribonuclease의 작용기전에 관한 연구

김용석,박무남,고재경 한양대학교 의과대학 1993 한양의대 학술지 Vol.13 No.1

Deoxyribonuclease (DNase) activity was determined in the bladder cancer tissue and was compared with that of the control tissue. The acid DNase known to be associated with carcinogenesis was isolated and purified from the bladder cancer tissue, and the substrate specificity and mechanism of action of the enzyme were studied to investigate the role of the acid DNase in the process involved in carcinogenesis of the bladder cancer. Activities of DNase Ⅰ,Ⅲ and Ⅳ were unchanged, but activity of DNase Ⅱ (acid DNase) was greatly increased in the bladder cancer tissue by a DEAE-cellulose column chromatography and the peak from the enzyme was greater in the cancer than in the control. The partially purified acid DNase from the bladder cancer tissue was highly active toward ds DNA, but still active toward ss DNA (18% of activity with ds DNA). The enzyme did not exhibit species specificity toward the substrates studied. Analyses for the ds DNA digest by the acid DNase from the bladder cancer tissue showed that majority of the products was oligodeoxyribonucleotides with chain length of 5-25. This indicated that the acid DNase was an endonuclease in nature. The acid DNase purified from the bladder cancer tissue was inhibited by RNA and polyribonucleotides, the degree of inhibition being changed with base sequence of the polyribonucleotides studied. The present study indicated that 1) the acid DNase in the bladder cancer tissue was greatly increased, 2) the enzyme was endonuclease in nature and 3) the enzyme activity was inhibited by RNA and polyribonucleotides, suggesting that the acid DNase in the bladder cancer tissue might play an important role in the process involved in carcinogenesis of the bladder cancer and that the process could be modified by RNA or polyribonucleotides.

중국산 식욕 억제제 복용으로 유발된 암페타민 의존 의증 1례

김석현,남정현,박용천 漢陽大學校 精神健康硏究 1999 精神健康硏究 Vol.18 No.-

익수환아의 예후에 영향을 미치는 인자에 관한 연구

김용배,정대봉,조수형,조남수,박영봉,박상기,김춘호,양은석,문경래 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.3

Drowning is the second most common cause of accidental death of children in Korea. But the study of near-drowning is very rare in Korea. The purpose of our study is to determine the factors that may influence survival on the basis of submersion time, consciousness state upon admission to hospital, the kinds of water, laboratory findings and neurological outcomes. The survey was performed by a retrospective cohort study on 28 near-drowning victims of less than 15 years of age who were admitted to the emergency room in the Chosun University Hospital between May 1988 & May 1997. The results were as follows :1)Sex distribution was 22 males and 6 females. 2) Submersion time was <5 minutes in 9 cases, 5-9 minutes in 6 cases, 10-14 minutes in 5cases, 15-19 minutes in 3 cases, ≥20 minutes in 5cases. 3) Comatose patients upon arrival were 6/7 cases in the death group(86%) and 2/21 cases in the improved group(10%). They had unfavorable outcomes(P<0.05). 4) The first PH value was mean 7.02±0.12 in the death group and mean 7.31±0.13 in the improved group. There was a statistically significant difference between the death and the improved group(P<0.05) 5) The patients who gad increased blood glucose concentration were all 7 cases in the death group and 12/22 cases in the improved group(54%). The mean blood glucose concentration was mean 424.7235.6㎎/㎗ in the death group and mean 140.182.7㎎/㎗ in the improved group. There was a statistically significant difference between the death and the improved group(P<0.05). 6) The patients who had pulmonary edema upon arrival were all 7 cases in the death group and 1/21 cases in the improved group(46%). They had unfavorable outcomes(P<0.05). 7) The patients who had been submerged more than 15 minutes were all 7 cases in the death group and 6/21 cases in the improved group(5%). They had unfavorable outcomes(P<0.05). We conclude that pediatric victims of near-drowning can be assigned to high or low likelihoods of unfavorable our outcomes with the use of five variables ; comatose mentation upon arrival decreased initial blood pH, increased initial blood glucose concentration, pulmonary edema, and maximum submersion time estimated longer than fiften minutes. This prediction rule may be useful if it can be validated in another cohort.

양측성 관상동정맥루 1예

최용원,오석규,이재훈,이상재,권경희,최은경,김남호,정진원 圓光大學校 醫科學硏究所 2002 圓光醫科學 Vol.17 No.1

저자들은 호흡곤란, 흉부불쾌감, 심계항진 등을 주소로 내원한 환자에서 경흉부 및 경식도 심초음파 검사상 주폐동맥에서 이완기에 전행하는 지속적인 혈류의 흐름을 관찰하고, 관상동맥 조영술을 통해 좌전하행지 중간부위와 우관상동맥 근위부에서 각각 기시하여 공통경로를 이루면서 주폐동맥으로 유입되는 양측성 관상동정맥루를 보이는 드문 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. A coronary arteriovenous fistula is infrequently encountered vascular communication between a coronary artery and a cardiac chamber, a great artery or the vena cava. It is the most common congenital anomaly that can affect coronary perfusion. Bilateral involvement of coronary fistula constitutes an uncommon subgroup of coronary arteriovenous fistulas. A 69 year-old female patient presented with chest discomfort, palpitation, and dyspnea. In the echocardiography, doppler color flow imaging visualized abnormal flow signals with mosaic appearance in the main pulmonary artery during diastolic phase. Coronary angiography revealed arteriovenous fistula arising from the left anterior descending artery and the right coronary artery. Both coronary arteriovenous fistulas drained into the main pulmonary artery. We report a case of bilateral coronary arteriovenous fistula that was confirmed by echocariography and coronary angiography.

뇌졸중후 우울증

문석우,서정석,남범우,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

In recent years, depression is most commonly reported psychiatric condition after stroke, poststroke depression(PSD) has attracted world-wide interest. This review focuses on the major research themes that have emerged. Pooled data from studies, have wide variation in results is due to different criteria for patient selection, different evaluation methods, diagnostic criteria and poststroke intervals, conducted throughout the world have found prevalence rates for from 18% to 65%. The diagnosis of PSD is most appropriately based on a structured mental state exam and DSM-N criteria for depression due to stroke with major depressive-like episode or depressive features. Rarely, poststroke patients may also develop bipolar mood disorder. The treatment of PSD, single antidepressant showing efficacy and electroconvulsive theraphy(ECT) and behavioral therapies have also effective. The progression of recovery following stroke can be altered by treating depression, which has been shown to improve recovery in activities of daily living(ADL) and cognitive impairment and to decreased mortality. The mechanisms underlying the association of stroke and mood disorder are important areas for future investigation.

파괴인성치 K_IC의 온도의존성에 관한 연구

최용식,석창성,조남걸 成均館大學校 科學技術硏究所 1991 論文集 Vol.42 No.1

Fracture toughness is generally known to be affected by the temperature. Especially in the low temperature region the fracture toughness is tend to lessen drastically because of the cleavage fracture and this temperature is called D.B.T.T.(ductile brittle transition temperature). This D.B.T.T. is important for safety design and the structure can be considered safe when the operating temperature is above the D.B.T.T. Therefore, for the purpose of evaluating the structural safety, plane strain fracture toughness(K_IC) measurements on SM45C steel amd PMMA were performed in the temperature range of -120∼-10℃. Test results show D.B.T.T. is observed around -10℃ in SM45C steel while no D.B.T.T. was observed in PMMA.

초등학교 교육과정과 교과서에 농업·농촌의 기능 및 가치 반영 방안

서우석,강대구,정남용,김재호,이윤조 한국농업교육학회 2006 농업교육과 인적자원개발 Vol.38 No.4

이 연구는 농업ㆍ농촌의 기능과 가치를 재정립하고 이를 초등학교 교육과정 및 교과서에 반영시킬 수 있는 방안을 제시하는데 그 목적이 있었다. 이를 위하여 먼저 선행연구 고찰을 통하여 농업ㆍ농촌의 기능과 가치를 재개념화하고, 이를 토대로 내용 분석 틀을 개발하여 초등학교 교육과정 및 교과서를 분석 하고, 그 결과를 토대로 교육과정 및 교과서에 반영시키기 위한 방안을 제시하였다. 그 주요 결과는 다음과 같다. 첫째, 농업ㆍ농촌의 기능과 가치는 크게 자연환경적 기능(수자원 함양 기능, 환경정화 기능, 생태계 보전기능, 자연재해 방지 기능), 사회문화적 기능(전통문화 보전 기능, 정서의 순화 기능, 자연학습의장 제공 기능), 사회경제적 기능(농산물 공급 기능, 직업 기회 제공 기능, 국토의 균형발전 기능, 타 산업에의 기여 기능)으로 분류하였다. 둘째, 농업ㆍ농촌의 기능과 가치를 바탕으로 초등학교 교육과정 및 교과서를 분석한 결과, 전 학년에 걸쳐서 자연학습의 장 제공 기능과 전통문화 보전 기능이 높게 나타났고, 그 다음으로는 농산물 공급기능과 정서순화기능이 높게 나타났다. 반면에 수자원함양기능과 환경정화기능은 상대적으로 낮게 나타났다. 셋째, 내용분석을 토대로 교과의 성격을 고려하여 각 교과별로 농업ㆍ농촌의 기능과 가치를 반영시킬 수 있는 방안을 제시하였다. 마지막으로, 각 교과별로 농업ㆍ농촌의 기능과 가치 반영 방안을 체계적으로 이행하기 위한 행ㆍ재정적 지원 방안을 교육과정 개발 측면, 교과서 개발 측면, 교육과정 운영측면, 정책적 지원 측면으로 구분 하여 제시하였다. The purpose of the study is to suggest the strategies for incorporating the roles and values of agriculture & rural areas as a part of the national curriculum and elementary school textbooks. For this purpose, this study was conducted as follows; First, we reclassified the roles and values of agriculture & rural areas after critically reviewing literature: environmental conservation functions, socio-cultural functions and socio-economic functions. Second, based on the new classification, we develop a framework for analyzing the national curriculum and elementary school textbooks. The functions of rural areas as places for learning about nature and purifying emotion and the importance of agriculture in providing agricultural product were frequently presented but the functions of sustaining water resources and environmental purification were relatively less presented in the national curriculum and elementary school textbooks. Third, we suggested strategies for incorporating the roles and values of agriculture & rural areas in the national curriculum and elementary school textbook based on the analysis. Finally, we suggested necessary administrative and financial assistance to systematically and effectively implement the suggested strategies for developing a new curriculum and textbooks as well as implementing the curriculum.