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Stroke and Bleeding Risk in Atrial Fibrillation
Keitaro Senoo,Deirdre Lane,Gregory YH Lip 대한심장학회 2014 Korean Circulation Journal Vol.44 No.5
Non-valvular atrial fibrillation (AF) is the most common cardiac arrhythmia in the clinical setting. AF increases both the risk and severityof strokes, and is associated with substantial morbidity and mortality. Despite the clear net clinical benefit of oral anticoagulants (OACs)in patients with AF at risk for stroke, major bleeding events, especially intracranial bleeds, may be devastating. In the last decade, four newOACs have been approved for stroke prevention in patients with AF and are at least as effective as warfarin with better bleeding profiles. These new agents have changed and simplified our approach to stroke prevention because the threshold for initiation of OACs is lowered. An important clinical practice shift is the initial identification of “low-risk” patients who do not need antithrombotic therapy, with low-riskcomprising CHA2DS2-VASc {Congestive heart failure, Hypertension, Age ≥75 years (double), Diabetes mellitus, previous Stroke/transientischemic attack/thromboembolism (double), Vascular disease, Age 65–74 years, and female gender (score of 0 for males and 1 for female)}. Subsequent to this step, effective stroke prevention consisting of OACs can be offered to patients with one or more stroke risk factors. Apart from stroke risk, another consideration is bleeding risk assessment, with a focus on the use of the validated HAS-BLED {Hypertension,Abnormal renal/liver function, Stroke, Bleeding history, Labile international normalized ratio (INR), Elderly (age >65 years), drugs or alcoholconcomitantly} score. A high HAS-BLED score can flag patients potentially at risk for bleeding, and alert clinicians to the need for carefulreview and follow up, and the need to consider potentially correctable bleeding risk factors that include uncontrolled hypertension,labile INRs, concomitant aspirin use, and alcohol excess.
Baseball Robots Based on Sensory-Motor Integration
Taku Senoo,Idaku Ishii 제어로봇시스템학회 2021 제어로봇시스템학회 국제학술대회 논문집 Vol.2021 No.10
In this paper, we provide an overview of the baseball robots we have developed. The system is composed of a high-speed hand-arm, a high-speed bipedal mechanism, and high-speed vision. By integrating these components, the system can perform feedback-based reactive motion in real time, unlike commonly used systems based on prediction and learning, to achieve high-speed movement. Using the characteristics, the system is able to perform baseball-relevant actions that require dynamic and high-speed body movements, including running, hitting, and fielding.