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      • Agreement of Iranian Breast Cancer Data and Relationships with Measuring Quality of Care in a 5-year Period (2006-2011)

        Keshtkaran, Ali,Sharifian, Roxana,Barzegari, Saeed,Talei, Abdolrasoul,Tahmasebi, Seddigheh Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

        Objectives: To investigate data agreement of cancer registries and medical records as well as the quality of care and assess their relationship in a 5-year period from 2006 to 2011. Methods: The present cross-sectional, descriptive-analytical study was conducted on 443 cases summarized through census and using a checklist. Data agreement of Nemazi hospital-based cancer registry and the breast cancer prevention center was analyzed according to their corresponding medical records through adjusted and unadjusted Kappa. The process of care quality was also computed and the relationship with data agreement was investigated through chi-square test. Results: Agreement of surgery, radiotherapy, and chemotherapy data between Nemazi hospital-based cancer registry and medical records was 62.9%, 78.5%, and 81%, respectively, while the figures were 93.2%, 87.9%, and 90.8%, respectively, between breast cancer prevention center and medical records. Moreover, quality of mastectomy, lumpectomy, radiotherapy, and chemotherapy services assessed in Nemazi hospital-based cancer registry was 12.6%, 21.2%, 35.2%, and 15.1% different from the corresponding medical records. On the other hand, 7.4%, 1.4%, 22.5%, and 9.6% differences were observed between the quality of the above-mentioned services assessed in the breast cancer prevention center and the corresponding medical records. A significant relationship was found between data agreement and quality assessment. Conclusion: Although the results showed good data agreement, more agreement regarding the cancer stage data elements and the type of the received treatment is required to better assess cancer care quality. Therefore, more structured medical records and stronger cancer registry systems are recommended.

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        In Vitro Comparison Study of Plasma Treated Bilayer PGS/PCL and PGS/PLA Scaffolds for Vascular Tissue Engineering

        Parisa Heydari,Shokoh Parham,Anousheh Zargar Kharazi,Shaghayegh Haghjooy Javanmard,Seddigheh Asgary 한국섬유공학회 2022 Fibers and polymers Vol.23 No.9

        Biomaterial selection is one of the important factors in tissue engineering vascular graft (TEVG) because of itshemocompatibility, mechanical properties, and biodegradability. In the present research, we prepared the bilayer electrospunscaffolds from poly glycerol sebacate (PGS)/poly caprolactone (PCL) and poly glycerol sebacate (PGS)/poly lactic acid(PLA), Then the surface of both groups was modified by using oxygen plasma. Physical, mechanical and hemocompatibilityevaluation of the bilayer PGS/PCL and PGS/PLA scaffold was performed to introduce a more suitable combination forTEVG applications. Results demonstrated that the plasma treatment process did not affect the surface morphology ofelectrospinning fibers but improved hydrophilicity, swelling ratio, and blood compatibility. It caused a faster degradation ratein treated groups. Mechanical tests of these scaffolds showed a proper mechanical strength for vascular tissue engineeringbefore and after plasma treatment, however, elongation of the PGS/PCL scaffolds was more suitable for vascular graftapplications. The hemocompatibility study showed improvement in platelet adhesion, hemolysis, and blood clotting timeafter plasma treatment in both groups also, there was no significant difference between the two scaffolds inhemocompatibility characteristics. It concluded that the treated bilayer PGS/PCL scaffold can be more suitable for vasculargraft application.

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