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Rajive Gupta,Satinder K. Juneja,Monika Gupta,Satya Paul 대한화학회 2008 Bulletin of the Korean Chemical Society Vol.29 No.12
A solvent-free procedure is developed for the regeneration of carbonyl compounds from aldoximes or ketoximes by grinding at room temperature and from hydrazone, phenylhydrazone or semicarbazone derivatives under microwave irradiation using dioxane-dibromide/SiO2. Products are obtained in excellent yields and are in a state of high purity.
Fatma Gassara,Satinder Kaur Brar,R. D. Tyagi,Rojan P. John,M. Verma,J. R. Valero 한국생물공학회 2011 Biotechnology and Bioprocess Engineering Vol.16 No.2
Lignin and manganese peroxidase (LiP, MnP)and laccase production by Phanerocheate chrysosporium was optimized by response surface methodology for brewery waste and apple pomace. The effect of moisture,copper sulphate, and veratryl alcohol (VA) concentrations on enzyme production was studied. Moisture and VA had significant positive effect on MnP and LiP production and the viability of P. chrysosporium (p < 0.05) and copper sulphate produced a negative effect. However, moisture and copper sulphate had a significant positive (p < 0.05) effect on laccase production, but VA had an insignificant positive effect (p < 0.05). Higher values of MnP, LiP and viability of P. chrysosporium on apple pomace (1287.5 U MnP/gds (units/gram dry substrate), 305 U LiP/gds, and 10.38 Log 10 viability) and brewery waste (792 U MnP/gds and 9.83Log 10 viability) were obtained with 80% moisture, 3mmol/kg VA, and 0.5 mmol/kg copper. LiP production in brewery waste (7.87 U/gds) was maximal at 70% moisture,2 mmol/kg VA, and 1 mmol/kg copper. Higher production of laccase in apple pomace (789 U/gds) and brewery waste (841 U/gds) were obtained with 80% moisture, 3 mmol/kg VA, and 1.5 mmol/kg copper. Thus, moisture along with VA and copper sulphate was pertinent for the production of ligninolytic enzymes and increased cell viability.
( Gurpreet Singh Dhillon ),( Satinder Kaur Brar ),( Surinder Kaur ),( Jose R. Valero ),( Mausam Verma ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.12
Enzyme extracts of cellulase [filter paper cellulase (FPase) and carboxymethyl cellulase (CMCase)], chitinase, and chitosanase produced by Aspergillus niger NRRL-567 were evaluated. The interactive effects of initial moisture and different inducers for FP cellulase and CMCase production were optimized using response surface methodology. Higher enzyme activities [FPase 79.24± 4.22 IU/gram fermented substrate (gfs) and CMCase 124.04±7.78 IU/gfs] were achieved after 48 h fermentation in solid-state medium containing apple pomace supplemented with rice husk [1% (w/w)] under optimized conditions [pH 4.5, moisture 55% (v/w), and inducers veratryl alcohol (2 mM/kg), copper sulfate (1.5 mM/kg), and lactose 2% (w/w)] (p<0.05). Koji fermentation in trays was carried out and higher enzyme activities (FPase 96.67±4.18 IU/gfs and CMCase 146.50±11.92 IU/gfs) were achieved. The nonspecific chitinase and chitosanase activities of cellulase enzyme extract were analyzed using chitin and chitosan substrates with different physicochemical characteristics, such as degree of deacetylation, molecular weight, and viscosity. Higher chitinase and chitosanase activities of 70.28±3.34 IU/gfs and 60.18±3.82 to 64.20±4.12 IU/gfs, respectively, were achieved. Moreover, the enzyme was stable and retained 92-94% activity even after one month. Cellulase enzyme extract obtained from A. niger with chitinolytic and chitosanolytic activities could be potentially used for making low-molecular-weight chitin and chitosan oligomers, having promising applications in biomedicine, pharmaceuticals, food, and agricultural industries, and in biocontrol formulations.
Vanita Ahuja,Deepak Thapa,Anjuman Chander,Satinder Gombar,Ravi Gupta,Sandeep Gupta 대한통증학회 2020 The Korean Journal of Pain Vol.33 No.2
Background: The effect of dexmedetomidine as an adjuvant in the adductor canal block (ACB) and sciatic popliteal block (SPB) on the postoperative tramadol-sparing effect following spinal anesthesia has not been evaluated. Methods: In this randomized, placebo-controlled study, ninety patients undergo-ing below knee trauma surgery were randomized to either the control group, using ropivacaine in the ACB + SPB; the block Dex group, using dexmedetomidine + ropi-vacaine in the ACB + SPB; or the systemic Dex group, using ropivacaine in the ACB + SPB + intravenous dexmedetomidine. The primary outcome was a comparison of postoperative cumulative tramadol patient-controlled analgesia (PCA) consumption at 48 hours. Secondary outcomes included time to first PCA bolus, pain score, neu-rological assessment, sedation score, and adverse effects at 0, 5, 10, 15, and 60 minutes, as well as 4, 6, 12, 18, 24, 30, 36, 42, and 48 hours after the block.Results: The mean ± standard deviation of cumulative tramadol consumption at 48 hours was 64.83 ± 51.17 mg in the control group and 41.33 ± 38.57 mg in the block Dex group (P = 0.008), using Mann–Whitney U-test. Time to first tramadol PCA bolus was earlier in the control group versus the block Dex group (P = 0.04). Other secondary outcomes were comparable. Conclusions: Postoperative tramadol consumption was reduced at 48 hours in pa-tients receiving perineural or systemic dexmedetomidine with ACB and SPB in below knee trauma surgery.
Prakriti Kapoor,Vishal Mehta,Rahul Bansal,Satinder Rana,Jatinderpal Singh,Ajit Singh 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.7
This paper describe design of novel sensor for moisture measurement that can be used in agriculture, automotive industries. In the present scenario moisture is measured by calculating change in relative permittivity which in turn depends upon change in capacitance of polymer layer sandwiched between electrodes. In this paper a new design is presented in which IDC sensor is used instead of Grid electrodes to calculate change in capacitance. Further, Comparative analysis has been done between these two topologies; device modeling has been carried out using COMSOL Multi-physics suite with MEMS approach.
Mrinal Patel,Devendra K. Dubey,Satinder Paul Singh 한국고분자학회 2021 Macromolecular Research Vol.29 No.10
Bombyx mori silk fibroin (B. mori SF) is a prospective and promising biomaterial being investigated by the scientific research fraternity around the world for its biomedical applications such as tissue engineered grafts. This consideration of silk fibroin as biomaterial is possible given its suitable mechanical and biological properties. Mechanical properties and behavior of a biopolymer or biomaterial are greatly affected by the chemical environment surrounding it. To assess the suitability of B. mori SF for application as tissue scaffold and graft, it is vitally essential to understand the influence of saline environment (such as provided by extracellular fluids in the physiological conditions and during pre and post-treatments of the fiber or scaffold) on its mechanical behavior and molecular mechanics. Current study investigates the tensile mechanical behavior of B. mori SF under varying saline environments (0 to 4.5 M) using molecular dynamics (MD) simulations. Elastic modulus values of 7 to 20 GPa and peak stress values of 350 to 750 MPa are computed for the two models for 0 to 4.5 M saline environments. Examining the obtained results show that peptide salt interactions are primarily contributing to the enhanced mechanical response of B. mori SF nanostructure. In addition, formation of ionic bridges between the salt ions present in saline environment and peptide strands, facilitating the enhanced mechanical response, are also observed. Ultimately, it is envisioned that the molecular deformation mechanisms and mechanistic understanding extracted from current study can be informative towards future investigation of silk-based biomaterials.
Spatio-temporal analysis of the climate impact on rice yield in north-west India
P. K. Kingra,Raj Setia,Satinder Kaur,Simranjeet Singh,Som Pal Singh,S. S. Kukal,B. Pateriya 대한공간정보학회 2018 Spatial Information Research Vol.26 No.4
The effects of climate, fertilizers and irrigation on rice yield and spatial variations of growing season climatic variability were analyzed in the three regions (Northwest, Central and South-west) of Indian Punjab from 1974 to 2013. There was a linear increase in rice yield in Punjab (30 kg ha-1 year-1 in north-east, 29 kg ha-1 year-1 in central and 34 kg ha-1 year-1 in south-west region) over 40 years. The results of Mann-Kendall test and Sen’s slope estimator showed an increase in minimum temperature (0.03 C year-1 in North-east Punjab and, 0.04 C year-1 each in Central and South-west Punjab) but no significant trend in maximum temperature and rainfall during the rice growing season (June–September). Among different climatic and technological variables, 49% of the variance in rice yield was explained by minimum temperature. Irrigation explained 33% of the remaining 51% variance in rice yield. The larger effect of climatic variables than fertilizer and irrigation suggest that adoption of climate smart and water conservation technologies are required to reduce rice yield variability in the future and improving food security. Spatial variations in yield, rainfall and temperature across Punjab were substantial and these have important consequences for food security by indicating the need for regionspecific technologies.