Computer Based an Analysis of Heart Rate Variability Signal in Prognosis of Diabetic Autonomic Neuropathy

SARIKA TALE,T.R.SONTAKKE 한국멀티미디어학회 2011 한국멀티미디어학회 국제학술대회 Vol.2011 No.-

The analysis of heart rate variability (HRV) signal is an important tool for studying the autonomic nervous system, as it allows the evaluation of the balance between the sympathetic and parasympathetic influences on heart rhythm. Time-frequency analysis of HRV makes it easier to evaluate how this balance varies with time. Among the various forms of autonomic disorders, Diabetic Cardiovascular Autonomic Neuropathy (DCAN) is a dreadful complication of diabetes therefore the use of HRV analysis in timely detection of diabetic autonomic neuropathy become of almost significance. This work presents a Electrocardiogram (ECG) signal preprocessing algorithm using Wavelet transform, a Pan-Tompkins algorithm for reliable QRS complex detection and to derive HRV signal from raw ECG signal. A tool for time domain analysis, Frequency domain analysis (Fast Fourier Transform (FFT), Auto-Regressive Model ing) of HRV signal developed in Matlab, Following the guidelines suggested by the Task force of the European Society of Cardiology. ECG data of 10 Diabetes Mellitus (DM) and 10 normal control volunteers were recorded and autonomic nervous system activities are quantified using the developed system. The analysis results shows a lower variation in time-frequency domain parameters of the Diabetics Mellitus (DM) patient group compared to normal subjects and p value <0.01.

Synthesis and Characterization of Some Quinazoline Derivatives as Potential Antimicrobial Agents under Microwave Irradiation

Sarika Mehta,Neelam Swarnkar,Madhuri Vyas,Jitendra Vardia,Pinki B. Punjabi,Suresh C. Ameta* 대한화학회 2007 Bulletin of the Korean Chemical Society Vol.28 No.12

Under the framework of green chemistry, an efficient and extremely fast procedure for the synthesis of 5a-h through four-step procedure starting from 2-arylidenetetralin-1-one 1a-d under microwave irradiation is described. A considerable increase in the reaction rate has been observed with better yield. The structures of the synthesized compounds have been characterized on the basis of their elemental analysis and spectral data. Synthesized compounds 5a-h was evaluated for their antimicrobial activity. Some of the compounds exhibited appreciable activity.

Recent Advances for Fabricating Smart Electromagnetic Interference Shielding Textile: A Comprehensive Review

Sarika Verma,Manish Dhangar,Sriparna Paul,Kamna Chaturvedi,Mohammed Akram Khan,Avanish Kumar Srivastava 대한금속·재료학회 2022 ELECTRONIC MATERIALS LETTERS Vol.18 No.4

A sharp elevation in the generation of electromagnetic interference (EMI) is observed, directly proportional to the increasein digital and electronic appliances. With the high growing population and enhancement in the number of electrical devicesused in personal, industrial and medical sites, the issues arising due to EMI are also at their peak. EM wave interference isknown to cause malfunctioning of the nearby electronic devices, destroying the signals and affecting human health, causingnausea, headaches, neural deformities etc. To avoid the harmful effect of these interferences, the personnel in its vicinity needa shielding material, protecting them from the ill effects of the electromagnetic waves. In this review article, EMI shieldingtextiles are being focused upon. Cotton, spandex, PET, PAN, silk fabric, etc., are modified through various methods andtechniques like drop-casting, layer-by-layer electrostatic self-assembly, click chemistry, and inkjet printing to perform thefunction of shielding of EM waves. These smart, flexible, hydrophobic and light weighing fabrics can be revolutionary indiminishing the deteriorating effects of EM waves in the human body. Surface modified having high electrical conductivitiesand EMI SE of up to and beyond 90 dB in various frequency ranges have been reported, providing promising and alternativepersonal protective equipment for electromagnetic interference shielding.

No Association of Hypoxia Inducible Factor-1α Gene Polymorphisms with Breast Cancer in North-West Indians

Sharma, Sarika,Kapahi, Ruhi,Sambyal, Vasudha,Guleria, Kamlesh,Manjari, Mridu,Sudan, Meena,Uppal, Manjit Singh,Singh, Neeti Rajan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

Background: Hypoxia inducible factor-1 alpha (HIF-$1{\alpha}$) is the key regulator of cellular responses to hypoxia and plays a central role in tumour growth. Presence of Single nucleotide polymorphisms (SNPs) in the critical regulatory domains of HIF-$1{\alpha}$ may result in the overexpression of the protein and subsequent changes in the expression of the downstream target genes. The aim of study was to investigate the association of three SNPs (g.C111A, g.C1772T and g.G1790A) of HIF-$1{\alpha}$ with the risk of breast cancer in North Indian sporadic breast cancer patients. Materials and Methods: A total of 400 subjects, including 200 healthy controls and 200 patients with breast cancer were recruited in this study. Genotypes were determined using polymerase chain reaction - restriction fragment length polymorphism (PCR-RFLP) method. Results: The CC and CA genotype frequency of HIF-$1{\alpha}$ g.C111A polymorphism was 100 vs 99% and 0 vs 1% in breast cancer patients and healthy controls respectively. The frequencies of CC, CT and TT genotype of g.C1772T polymorphism were 76 vs 74.5%, 19 vs 21% and 5 vs 4.5% in breast cancer patients and control individuals respectively. There was no significant difference in genotype and allele frequencies of HIF-$1{\alpha}$ g.C1772T polymorphism between cases and control individuals (p>0.05). For g.G1790A genotypes, all patients and controls had only GG genotype. Conclusions: The three HIF-$1{\alpha}$ polymorphisms (g.C111A, g.C1772T and g.G1790A) are not associated with breast cancer risk in North-West Indian patients.

TP53 Polymorphisms in Sporadic North Indian Breast Cancer Patients

Sharma, Sarika,Sambyal, Vasudha,Guleria, Kamlesh,Manjari, Mridu,Sudan, Meena,Uppal, Manjit Singh,Singh, Neeti Rajan,Bansal, Darpan,Gupta, Arun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16

Background: The purpose of this study was to evaluate the potential association of five (p.P47S, p.R72P, PIN3 Ins16bp, p.R213R and r.13494g>a) polymorphisms of TP53 with the risk of developing breast cancer in North Indian Punjabi population. Methods: We screened DNA samples of 200 sporadic breast cancer patients (197 females and 3 males) and 200 unrelated healthy, gender and age matched individuals for the polymorphisms. Results: For the p.P47S polymorphism, we observed the PP genotype in 99.5% of the patients and PS genotype in only 1 patient. All the controls had the wild type PP genotype. The frequency of RR, RP and PP genotype of p.R72P was 23.5% vs 33.5%, 51.5% vs 45.5% and 25% vs 21% in patients and controls respectively. Heterozygous (RP) genotype was increased in breast cancer patients as compared to controls (51.5 vs 45.5%) and showed 1.61 fold significantly increased risk for breast cancer (OR=1.61, 95% CI, 1.01-2.58, p=0.04). In breast cancer patients the frequencies of A1A1, A1A2 and A2A2 genotypes of PIN3 Ins16bp polymorphism were 67%, 26% and 7% respectively whereas in controls the genotype frequencies were 68.5%, 27.5% and 4% respectively, with no significant difference. For p.R213R (c.639A>G), all individuals had homozygous wild type genotype. The frequencies of GG, GA and AA genotypes of TP53 r.13494g>a polymorphism were 62 vs 67.5%, 33 vs 28% and 5 vs 4.5% in patients and controls respectively, again without significant difference. We observed that RP-A1A1 genotype combination of p.R72P and PIN3 Ins16bp and RP-GG combination of p.R72P and r.13494g>a polymorphism showed significant risk of breast cancer (OR=1.65, 95%CI: 0.98-2.78, p=0.05; OR=1.72, 95%CI: 1.01-2.92, p=0.04). Conclusion: The results of present study indicated that among the five TP53 polymorphisms investigated, the p.R72P polymorphism, and the RP-A1A1 and RP-GG genotype combination contribute to breast cancer susceptibility in North Indians.

Synthesis and Characterization of Some Quinazoline Derivatives as Potential Antimicrobial Agents under Microwave Irradiation

Mehta, Sarika,Swarnkar, Neelam,Vyas, Madhuri,Vardia, Jitendra,Punjabi, Pinki B.,Ameta, Suresh C. Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.12

Under the framework of green chemistry, an efficient and extremely fast procedure for the synthesis of 5a-h through four-step procedure starting from 2-arylidenetetralin-1-one 1a-d under microwave irradiation is described. A considerable increase in the reaction rate has been observed with better yield. The structures of the synthesized compounds have been characterized on the basis of their elemental analysis and spectral data. Synthesized compounds 5a-h was evaluated for their antimicrobial activity. Some of the compounds exhibited appreciable activity.

Rotor Material Selection for High-Speed Double Cage Solid Rotor Induction Motor

Kalra Sarika 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.4

This paper presents the effect of various materials on the performance of a 3-phase, 180 kW, 170 Hz, high-speed double cage solid rotor induction motor using ANSYS MAXWELL 2-D software. The double cage rotor has been simulated with different materials for the upper cage and lower cage. It has been observed that in the double cage rotor, both lower cage and upper cage of aluminum is a better choice because it furnishes the large starting torque, lower torque ripple and more value of average torque in comparison to case when lower cage is of copper material and upper cage is of aluminum. The effect of different types of rotor core materials and end ring materials on motor performance has also been analyzed and the material, M19_24G, has been found an improved choice compared to other rotor core materials owing to production of higher average torque with lower value of torque ripple. For end ring material, BeCu, has been discovered the better choice because it renders the highest starting torque and better power factor without compromising the mechanical strength of the motor.

Oral Health of Stone Mine Workers of Jodhpur City, Rajasthan, India

Jitender Solanki,Sarika Gupta,Sachin Chand 한국산업안전보건공단 산업안전보건연구원 2014 Safety and health at work Vol.5 No.3

Background: Occupational injuries cause major health problems, which the developed, developing, andunderdeveloped nations worldwide are facing today. The present study aimed to assess dental caries,periodontal health of stone mine workers, and the relationship between wasting diseases and the yearsof working experience. Methods: The study population comprised 510 men, selected based on the stratified cluster samplingprocedure. Clinical oral examinations were carried out, and periodontal disease, dental caries, andwasting diseases were recorded. Results: Workers were in the age group of 17e56 years; the prevalence of dental caries in the workerswas found to be 74%, with a mean decayed, missing, filled teeth index of 2.89. A periodontal pocket ofmore than 6 mm was observed in 6% of the workers. Conclusion: The oral health of mine workers is in a poor state; steps should be taken so as to providebasic medical and dental care facilities.

Optimization of Reaction Conditions for High Yield Synthesis of Carbon Nanotube Bundles by Low-Temperature Solvothermal Process and Study of their H2 Storage Capacity

G. Krishnamurthy,Sarika Agarwal 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.10

Synthesis of Carbon Nanotube bundles has been achieved by simple and economical solvothermal procedure at very low temperature of 180 °C. The product yield obtained was about 70-75%. The optimization of reaction conditions for an efficient synthesis of CNTs has been presented. The CNTs are obtained by reduction of hexachlorobenzene in the presence of Na/Ni in cyclohexane. The X-ray diffraction, Fourier transform infrared and Raman spectral studies have inferred us the graphene structure of the products. The CNTs formed as the bundles were viewed on scanning electron microscope, transmission electron microscope and high-resolution transmission electron microscope. These are the multiwalled CNTs with outer diameter of 5-10 nm, the inner diameter 2-4 nm and cross sectional diameter up to 5 nm. Brunauer-Emmett-Teller (BET) based N2 gas adsorption studies have been made to obtain BET surface area and H2 storage capacity. Effect of the experimental variables such as reaction temperature, amount of catalyst and the amount of carbon source were investigated. It is found that they affect significantly on the product nature and yield.

Evaluation of Strong Microwave Absorption Property of PVB-PEDOT:PSS-Ti3C2Tx MXene Nanocomposite With Materials Data-Driven Discovery

M. Praveen Kumar,Sarika Raga,S. Chetana,K. Avinash,Arjun Dey,Dinesh Rangappa 한국전기전자재료학회 2023 Transactions on Electrical and Electronic Material Vol.24 No.3

2D nanomaterial, especially 2D metal carbides or MXene loaded polymer nanocomposite is highly valued electromagnetic material. In this work, Ti3C2TX MXene loaded polyvinyl butyral (PVB)-Poly(3,4-ethylenedioxythiophene)-poly(styrene sulfonate) (PEDOT:PSS)-Ti3C2TX MXene nanocomposite is explored for microwave absorption in the frequency range of X-Band and Ku-Band (8.2–18 GHz). The reflection loss (RL) of the optimized PEDOT:PSS content PVB-PEDOT:PSS was found to improve significantly in presence of the Ti3C2TX MXene viz., 5%, 10%, 20% and 40%. Ti3C2TX MXene loaded solution processed PVB-PEDOT:PSS-Ti3C2TX MXene indicates RL is strongly effected by Ti3C2TX MXene loading. To optimize Ti3C2TX MXene content in PVB-PEDOT:PSS-Ti3C2TX MXene nanocomposite for best RL with minimum thickness, the materials data-driven discovery was used for which experimental data sets were used as input parameters. Through the materials data-driven discovery, the minimum RL value -63 dB was predicted at 2.6 mm for 18 wt% Ti3C2TX MXene loaded PVB-PEDOT:PSS-Ti3C2TX MXene nanocomposite which was not examine before. The predicted RL data for the optimized PVB-PEDOT:PSS-Ti3C2TX MXene nanocomposite (18 wt% MXene content) was compared with the experimental data.