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Modeling of pressuremeter tests to characterize the sands
Oztoprak, Sadik,Sargin, Sinan,Uyar, Hidayet K.,Bozbey, Ilknur Techno-Press 2018 Geomechanics & engineering Vol.14 No.6
This paper proposes a numerical methodology for capturing the complete curve of a pressuremeter test including initial or disturbed parts and loops through a stiffness-based approach adopted in three dimensional finite difference code, FLAC3D. In order to enable this, a new hyperbolic model was used to replace the conventional linear elastic model prior to peak strength of Mohr-Coulomb soil model and update or degradation of shear modulus was considered. Presented modeling approach and implemented constitutive model are impressively successful. It leads to obtain the whole set of parameters for characterizing sands and seems promising for modeling the most of geotechnical structures.
Epileptic Seizure Due to Disulfiram Treatment
Habib Erensoy,Ahmet Emre Sargin 대한가정의학회 2019 Korean Journal of Family Medicine Vol.40 No.6
Disulfiram has been used for the treatment of alcohol dependence for nearly 65 years and is approved by the Food and Drug Administration. It causes negative reinforcement by accumulating toxic acetaldehyde due to irreversible inhibition of aldehyde dehydrogenase. Disulfiram has very few side effects when taken without alcohol. Epileptic seizure induction is a rare side effect in therapeutic doses, and its mechanism is unknown. We present a patient with a single epileptic seizure which was thought to be due to disulfiram used in the treatment of alcohol dependence. We did not find it ethical to administer disulfiram again because the patient discontinued alcohol use and was afraid of epileptic seizures.
Murat Kaya,Idris Sargin,Volkan Aylanc,Muhammed Nebi Tomruk,Seda Gevrek,Isil Karatoprak,Nazlican Colak,Yasar Gul Sak,Esra Bulut 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.38 No.-
Bovine serum albumin is the key protein in blood. Chitin is a widely used biocompatible polymer inbioengineering and it is mainly found as two allomorphs (a, b). In this study the interactions of a-chitin(from the insect Omophlus sp.) and b-chitin (from the cuttlebone of Sepia sp.) with BSA were studied. Chitin isolates were examined by SEM, XRD, BET, TGA and FTIR. b-Chitin exhibited a far higher affinity forBSA than a-chitin, indicating a-chitin can be used in applications where surface–protein interactionsshould be limited, and b-chitin can be used in chitin-based materials on which protein adsorption isdesired.
Murat Kaya,Lalehan Akyuz,Idris Sargin,Muhammad Mujtaba,Asier M. Salaberria,Jalel Labidi,Yavuz S. Cakmak,Behlul Koc,Talat Baran,Talip Ceter 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.47 No.-
Sporopollenin-chitosan blendfilms were produced for thefirst time. Sporopollenin is a robust structuralcomponent of plant pollens exhibiting excellent features such as nontoxicity, biodegradability,biocompatibility, high thermal stability, durability to strong acid and base solutions and homogeneityin size. To benefit from these advantages, sporopollenin samples obtained from Betula pendula (silverbirch) were incorporated into chitosanfilm at different concentration; 10, 20 and 40 mg in 100 mLchitosan gel (1%). Stereo microscopy, FT-IR and TG/DTG analyses showed that sporopollenin wassuccessfully incorporated into the chitosan matrix. Incorporation of sporopollenin in gradually increasingamount into chitosanfilms was found advantageous in (1) enhancement in chemical durability of thefilms, (2) increment of hydrophobicity, (3) boosting the mechanical properties, (4) improvement ofantifungal and (5) antioxidant activities. This study revealed that sporopollenin can be suggested as aneffective blend material for biodegradable edible chitosanfilm production.
( Ozgur Tanriverdi ),( Nezih Meydan ),( Sabri Barutca ),( Gurhan Kadikoylu ),( Gokhan Sargin ),( Canten Tataroglu ),( Nil Culhaci ) 대한피부과학회 2013 Annals of Dermatology Vol.25 No.1
Skin metastasis of primary gallbladder tumors is extremely rare with a reported incidence of 0.7∼9% and it usually involves the thorax, abdomen, the extremities, neck, head region, and scalp. Cutaneous metastasis may occur synchronously or metatochronously. In the present case, the patient had chronic lymphocytic leukemia, which was being treated with an alkylating agent (chlorambucil) when the patient developed skin metastasis from gallbladder adenocarcinoma during post- cholecystectomy follow-up. Given the fact that secondary malignancies occur in chronic lymphocytic leukemia; this clinical setting warrants attention. We aimed to discuss secondary malignancy in chronic lymphocytic leukemia patients and gallbladder adenocarcinoma with skin metastasis, based on a review of the literature and the presented case. (Ann Dermatol 25(1) 99∼103, 2013)