http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Javier Vázquez-Bourgon,Ignacio Mata,Roberto Roiz-Santiáñez,Rosa Ayesa-Arriola,Paula Suárez Pinilla,Diana Tordesillas-Gutiérrez,José Luis Vázquez-Barquero,Benedicto Crespo-Facorro 대한신경정신의학회 2014 PSYCHIATRY INVESTIGATION Vol.11 No.2
Objective DISC1 gene is one of the main candidate genes for schizophrenia since it has been associated to the illness in several populations. Moreover, variations in several DISC1 polymorphisms, and in particular Ser704Cys SNP, have been associated in schizophrenic patients to structural and functional modifications in two brain areas (pre-frontal cortex and hippocampus) that play a central role in the genesis of psychotic symptoms. This study tested the association between Ser704Cys DISC1 polymorphism and the clinical onset of psychosis. Methods Two hundred and thirteen Caucasian drug-naïve patients experiencing a first episode of non-affective psychosis were genotyped for rs821616 (Ser704Cys) SNP of the DISC1 gene. The clinical severity of the illness was assessed using SAPS and SANS scales. Other clinical and socio-demographic variables were recorded to rule out possible confounding effects. Results Patients homozygous for the Ser allele of the Ser704Cys DISC1 SNP had significantly (p<0.05) higher rates at the positive symptoms dimension (SAPS-SANS scales) and hallucinations item, compared to Cys carriers. Conclusion DISC1 gene variations may modulate the clinical severity of the psychosis at the onset of the disorder.
Santi Devi Upadhaya,Woo Jeong Seok,Shanmugam Suresh kumar,Rudolf H. van der Veen,In Ho Kim 한국축산학회 2023 한국축산학회지 Vol.65 No.3
The aim of the present study was to evaluate the effects of dietary supplementation of Ca-Mg complex on the longevity and reproductive performance of sows. In total, seventy-two gilts ([Yorkshire × Landrace] × Duroc, average body weight 181 kg) were randomly allocated to 1 of 3 treatments during 4 successive parity in a 4 × 3 factorial arrangement. Treatments consisted of CON (basal diet), CM1 (basal diet -MgO - 0.3% limestone + 0.4% Ca-Mg complex), and CM2 (basal diet - MgO - 0.7% limestone + 0.4% Ca-Mg complex). A higher (p < 0.05) number of totals born and live piglets, and sows increased feed intake during gestation and lactation, increased backfat thickness, and increased estrus interval were observed (p < 0.05) during their third and fourth parity than during their first and second parity. Ca-Mg complex supplementation improved (p < 0.05) the number of total piglets during the first and second parity as well as live-born piglets during the first to third parity, reduction (p < 0.05) in backfat thickness during the third and fourth parity, a higher (p < 0.05) initial and final number of suckling piglets as well as higher weaning weight compared with sows fed CON diet during the first, second, and third parity. The average daily gain (ADG) was higher (p < 0.05) in piglets born to CM1 and CM2 sows regardless of parity. The treatment diets fed to sows lowered (p < 0.05) the duration of first to last piglet birth and placenta expulsion time compared with CON sows. A significant interactive effect (p = 0.042) between parities and treatment diets was observed for the first to last piglet birth. Thus, Ca-Mg complex supplementation by partially replacing limestone in the basal diet enhanced sow performance, specifically during their third and fourth parity, thereby improving sow longevity.
Phenolic Compounds in Antimicrobial Therapy
Santi M. Mandal,Renata O. Dias,Octavio L. Franco 한국식품영양과학회 2017 Journal of medicinal food Vol.20 No.10
Long-term treatment with several conventional antibiotics can cause harmful side effects that can be alleviated by antioxidant therapy. Phenolic compounds (PCs) are the best source of antioxidants, and to identify the most suitable polyphenols for use as a supportive supplement during antibiotic therapy, this study screened a series of PCs to establish their antibacterial potential, including their biofilm and β-lactamase inhibition activity. Several PCs were tested for antibacterial activity against Staphylococcus epidermidis and Pseudomonas aeruginosa. Among them, tannic acid, epigallocatechin gallate, rutin, and eugenol showed the highest antibacterial activity. Epigallocatechin gallate, tannic acid, quercetin, and epicatechin inhibited a significant level of β-lactamase activity. Tannic acid and epigallocatechin gallate presented the highest β-lactamase inhibition potential in both in vitro and in silico analysis. In the present work, these two PCs were the most active agents, presenting both antibacterial activity and β-lactamase and biofilm inhibition ability.
Santi Marina Rodrigues,Lins Rodrigo Barros Esteves,Sahadi Beatriz Ometto,Denucci Giovanna Corrêa,Soffner Gabriela,Martins Luís Roberto Marcondes 대한치과보존학회 2022 Restorative Dentistry & Endodontics Vol.47 No.3
Objectives This study aimed to evaluate the influence of inorganic composition and filler particle morphology on the mechanical properties of different self-adhesive resin cements (SARCs). Materials and Methods Three SARCs including RelyX Unicem-2 (RUN), Maxcem Elite (MAX), and Calibra Universal (CAL) were tested. Rectangular bar-shaped specimens were prepared for flexural strength (FS) and flexural modulus (FM) and determined by a 3-point bending test. The Knoop microhardness (KHN) and top/bottom microhardness ratio (%KHN) were conducted on the top and bottom faces of disc-shaped samples. Sorption (Wsp) and solubility (Wsl) were evaluated after 24 hours of water immersion. Filler morphology was analyzed by scanning electron microscopy and X-ray energy dispersive spectroscopy (EDS). FS, FM, %KHN, Wsp, Wsl, and EDS results were submitted to 1-way analysis of variance and Tukey’s post-hoc test, and KHN also to paired t-test (α = 0.05). Results SARC-CAL presented the highest FS value, and SARC-RUN presented the highest FM. SARC-MAX and RUN showed the lowest Wsp and Wsl values. KHN values decreased from top to bottom and the SARCs did not differ statistically. Also, all resin cements presented carbon, aluminum, and silica in their composition. SARC-MAX and RUN showed irregular and splintered particles while CAL presented small and regular size particles. Conclusions A higher mechanical strength can be achieved by a reduced spread in grit size and the filler morphology can influence the KHN, as well as photoinitiators in the composition. Wsp and Wsl can be correlated with ions diffusion of inorganic particles.
Earthquake activities in the Philippines Islands and the adjacent areas
Santi Pailoplee,Natchana Boonchaluay 한국지질과학협의회 2016 Geosciences Journal Vol.20 No.6
This study focused on the seismic activities in the Philippines Islands and the adjacent areas where the inter- and intra-plate seismic sources are prevalent. To access this, the frequency-magnitude distribution model was employed with the completeness seismicity data. Then, the possible maximum magnitude, return period and probability of earthquake occurrence, including the prospective areas of upcoming earthquakes, were evaluated. The results indicated that eastern Taiwan is among the most seismic-prone areas. The most probable largest magnitude of earthquakes was estimated to be up to 8.0 Mw in a time period of 50 years, giving return periods of <1, 2–4, 5–20 and 20–40 years for earthquakes with a Mw of 5.0, 6.0, 7.0 and 8.0, respectively. Meanwhile, in the areas of Davao and eastern Manado, where the group of Halmahera, Philippines and Sangihe Double Subduction Zones are delineated (HSZ, PSZ and SSZ, respectively), maximum earthquakes of 6.8–7.1 Mw are possible in a 5–10 year period. For the northern Minahassa and eastern Sulu Trenches (MST and SLT), which were defined as medium hazard areas, the return periods were calculated at ~100–200 years for an earthquake magnitude of 7.0–8.0 Mw. According to the limits of the recorded earthquake events, the Palawan, Sulu Archipelago and Sulu Trenches (PWT, SAT and SLT, respectively) are classified as aseismic source zones. For earthquake forecasting, six locations along the Manila Trench (MLT), HSZ, PSZ and SAT are proposed as the areas that have a high probability of generating a major earthquake in the near future. Geographically, the most prospective areas are located near major cities, such as Taipei, Manila, Davao and Manado. Thus, there is a compelling need to develop effective mitigation strategies for both tsunami and earthquake hazards.
Santi Theresia,Kamarga Lina,De Samakto Baringin,Jo Juandy 대한감염학회 2022 Infection and Chemotherapy Vol.54 No.4
It remains unknown whether the Indonesian healthcare workers (HCWs) who had received two doses of CoronaVac vaccine and one dose of mRNA-1273 booster could be protected during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron wave. In total, 125 infection-naïve and 10 previously infected HCWs were recruited. The mRNA-1273 booster substantially increased titer of anti-SARS-CoV-2 spike protein receptor-binding domain antibodies. However, the monitoring revealed that 34 out of 125 infection-naïve (27.2%) and 3 out of 10 previously infected HCWs (30.0%) were infected during the Omicron wave. All infected HCWs were either asymptomatic or having mild coronavirus disease 2019 (COVID-19) and subsequently fully recovered, supporting the heterologous prime-boost strategy against COVID-19.
Communication Pattern of Indonesian Parents-Children and Its Role in Buying Decision
Santi Budiman,Tony Wijaya People&Global Business Association 2016 Global Business and Finance Review Vol.21 No.1
This research has purpose to test the influence of communication pattern of parents and children, that is concept and social orientation toward the children role as the influencer in buying decision making in Indonesia. Sample in this research is dyadic sample that involves parents and children. The sampling was done with purposive sampling method. One hundred and twenty respondents had been successfully collected in this research. Data was collected using questionnaire. Data analysis used regression analysis. This research result shows that the communication pattern of parents that is social-oriented does not significantly influence the children role as the influencer in buying decision. Parents communication pattern that is concept-oriented influences positively the children role as the influencer in buying decision.
Probabilistic analysis of the seismic activity and hazard in northern Thailand
Santi Pailoplee,Punya Charusiri 한국지질과학협의회 2015 Geosciences Journal Vol.19 No.4
The seismic activity and hazard level in northern Thailand, including at the Mae Moh Coal Mine (MMCM), were clarified. For the probability of exceedance (POE), Chiang Mai, Lamphun, and Lampang provinces have a 70–90% and 20–40% POE of a MW-5.0 and MW-6.0 earthquake, respectively, in the next 50 y. In the case of a MW-7.0 earthquake, the POE is less than 10% in the whole study area. Regarding the probabilistic seismic hazard analysis, the ground shaking maps indicated that the southeastern part of the MMCM and northwestern part of Phayao provinces were high hazard areas, with an earthquake ground shaking of around 0.28–0.32g and 0.18–0.24g for a POE of 2% and 10%, respectively, in the next 50 y. In addition, the probability maps revealed that these high hazard areas showed a 60–80% and 30–40% POE of a modified Mercalli intensity (MMI) level III and IV, respectively, in the next 50 y. The low hazard areas of Chiang Mai and Uttaradit provinces had a ground shaking level for a 2% and 10% POE in the next 50 y of around 0.16 and 0.08, respectively, with a POE of a MMI level III or IV of less than 20% each.
Santi Devi Upadhaya,Ha Guyn Sung,Chan Hee Lee,이세영,Sun Woo Kim,Kyung Jin Cho,하종규 대한수의학회 2009 Journal of Veterinary Science Vol.10 No.1
The aflatoxin B1 degrading abilities of two different ruminants were compared in this study. One set of experiments evaluated the aflatoxin B1 degradation ability of different rumen fluid donors (steers vs. goats) as well as the rumen fluid filtration method (cheese cloth filtered vs. 0.45 μm Millipore) in a 2 × 2 factorial arrangement. Additional studies examined aflatoxin B1 degradation by collecting rumen fluid at different times (0, 3, 6, 9 and 12 h) after feeding. Cannulated Holstein steers (740 ± 10 kg bw) and Korean native goats (26 ± 3 kg bw) were fed a 60% timothy and 40% commercial diet with free access to water. Rumen fluid from Korean native goats demonstrated higher (p < 0.01) aflatoxin B1 degradability than Holstein steers. However, filtration method had no significant influence on degradability. In addition, aflatoxin degradation did not depend upon rumen fluid collection time after feeding, as no significant differences were observed. Finally, a comparison of two types of diet high in roughage found aflatoxin degradability in goats was higher with timothy hay opposed to rice straw, although individual variation existed. Thus, our findings showed the aflatoxin degradability is comparatively higher in goats compared to steers.