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Acute Effects of Dried Apple Consumption on Metabolic and Cognitive Responses in Healthy Individuals
Kara Sansone,Mark Kern,홍미영,Changqi Liu,Shirin Hooshmand 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.11
The objective of this study was to assess the potential of dried apple to regulate acute blood glucose, insulin, satiety, and total plasma antioxidant levels, and to explore the effect of dried apple on cognitive responses. Twenty-one healthy, normal-weight subjects completed the study which used a randomized crossover design with repeated measures. After a fast of 10 h, a standardized serving size of either dried apple or muffins was consumed. Blood glucose, insulin, and antioxidant concentrations were measured at 0, 15, 30, 45, 60, 90, and 120 min postprandial, and satiety was assessed every 15 min for 2 h. Cognitive tests were administered before and 2 h after consumption of the test food. The dried apple had significantly higher phenolic content and antioxidant activities than the muffin (P ≤ .05). Consumption of the dried apples produced significantly lower glucose concentrations at 30- (P ≤ .01; 95% CI [2.93–16.64]), 45- (P ≤ .02; 95% CI [2.41–17.88]), 60- (P ≤ .02; 95% CI [2.10–14.56]), and 120-min (P ≤ .01; 95% CI [8.16–16.80]) time points, and significantly lower (P ≤ .03; 95% CI [0.60–8.70]) insulin concentrations at a 15-min time point than the muffins but offered little consistent differences in antioxidant status, satiety, and cognitive function. These findings suggested that the intake of dried apples could reduce postprandial blood glucose and potentially increase the effectiveness of insulin responses in healthy individuals but offered little consistent differences in antioxidant status, satiety, and cognitive function.
Federica Cozza,Andrea Lizio,Lucia Catherine Greco,Stefania Bona,Giordana Donvito,Elena Carraro,Silvia Tavazzi,Nicola Ticozzi,Barbara Poletti,Valeria Ada Sansone,Christian Lunetta 대한신경과학회 2021 Journal of Clinical Neurology Vol.17 No.1
Background and Purpose The study aimed to obtain optometric findings of amyotrophic lateral sclerosis (ALS) patients in different stages of the disease, and to determine the relation between ocular data and ALS-related features; that is, functional and cognitive impairment and staging. Methods The optometric protocol included tests of the ocular motility [broad-H test and Northeastern State University College of Optometry (NSUCO) test], near point of convergence (NPC), error refraction, best-corrected visual acuity, and binocular visual alignment, and an ocular symptoms questionnaire. The functional measures included the Amyotrophic Lateral Sclerosis Functional Rating Scale–revised (ALSFRS-r) and Milano-Torino staging (Mi- ToS), and cognitive impairment was assessed using the Edinburgh Cognitive and Behavioural ALS Screen (ECAS). Demographic and clinical features were also collected, including whether the patients used an eye-tracking communication device (ETCD). Results Two-hundred consecutive ALS patients (median age of 64 years, 118 males and 82 females) in different stages of disease were recruited. Nearly 70% of patients reported at least one ocular symptom, and the use of an ETCD was found to be significantly related to the presence of most symptoms. Moreover, the severely symptomatic group was characterized by significantly lower ALSFRS-r total and subscale scores, and higher MiToS. Abnormal NPC values were significantly related to lower ALSFRS-r total and bulbar-subscale scores. Patients with acceptable NSUCO test values exhibited significantly higher ECAS scores. Conclusions The presence of ocular alteration in patients in different stages of ALS supports the idea that this is a multisystem disorder and emphasizes the importance of optometric evaluations in multidisciplinary assessments to address ocular impairment early in the disease process
Stainless Steel Porous Substrates Produced by Tape Casting
Elisa Mercadelli,Angela Gondolini,Paola Pinasco,Alessandra Sanson 대한금속·재료학회 2017 METALS AND MATERIALS International Vol.23 No.1
In this work the technological issues related to the production of tape cast large-area porous stainless steel supports for Solid Oxide Fuel Cells (SOFC) applications were carefully investigated. The slurry formulation was optimized in terms of amount and nature of the organic components needed: rice starch and polymethyl metacrylate were found to be, respectively, the most suitable pore former and binder because easily eliminated during the thermal treatment in reducing atmosphere. The compatibility of the binder system chosen with the most widely used solvents for screen printing inks was also evaluated. Finally the influence of the sintering temperature and of the refractory supports to be used during the thermal treatments onto the production of porous stainless steel supports was discussed. The whole process optimization allows to produce flat, crack-free metallic substrate 900-1000 μm thick, dimensions up to 5×5 cm and with a tailored porosity of 40% suitable for SOFCs application.
Shin, Dong Wook,Kim, So Young,Cho, Juhee,Sanson-Fisher, Robert W,Guallar, Eliseo,Chai, Gyu Young,Kim, Hak-Soon,Park, Bo Ram,Park, Eun-Cheol,Park, Jong-Hyock Grune Stratton ; American Society of Clinical Onco 2011 Journal of clinical oncology Vol.29 No.33
<P>Identification of supportive care needs in patients with cancer is essential for planning appropriate interventions. We aimed to determine patient-physician concordance in perceived supportive care needs in cancer care and to explore the predictors and potential consequences of patient-physician concordance.</P>