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朴相采,宋昊哲,金東熙,徐榮培,朴陽春,金聖勳 대한본초학회 2000 大韓本草學會誌 Vol.15 No.1
To evaluate the antitumm activity and immune rsponse of Bujunghoedo!aaCtnng(BJHDn, studies were done experimentally. The rsulLF were OMaineed as fallow: 1. BJHDT e m c b erhibitcd a wmk eytotoxieity against SKOV-3, and SK-MELJ cell lines, while it showed a good effectivaes against BlE-FIO up to 80% of control at concenmion of over 0.25mg/ml 2. BJHDT emcG signifimtly showed an inhibitor, effect on DNA topowmewz I from calf thpw at 500 mglmf. 3. BJHDT eXhaetS showed antiadhesive rates against A549, 30% at 0.5 dm!, 80% at 1 mplm!. 4. BJHDT exmcb inhibited CAM angiogenesis up to 40%. 6. BIHDT extracb prolonged life span of ICR mice bearing S-180 sarcoma cells up to 127.1%. 7. In FACS analysis, the population of helper T cell and tended to increase. 8. Pmliferatbn rate of splenoeyte WBS inneased at 0.5mglml or more in a dase dependent fashim as compared with Control. These resulb suggested that BIHDT exham might k usefully applied for treatment of cancer and also it was necessary m do more studies about its mechanisms.
鄭泰秀,鄭聖云 成均館大學校 科學技術硏究所 1986 論文集 Vol.37 No.2
In the separation by liquid surfactant membrane of benzene-n-hexane mixture both components of which have similar physical properties, studied were the effects on the separation factor of the stirring speed for emulsification, stirring, speed of the emulsion and the solvent, surfactant and glycerol concentration. The main findings are as follows; 1. The separation factor increased with increasing stirring speed in mixing the emulsion with the solvent. At the stirring speed of about 230 rpm, the separation factor was maximum, and then the separation factor decreased as the stirring speed increased. 2. The separation factor increased almost linearly with stirring speed in emulsification, which was due to the increased total surface area and increased stability of droplets. 3. The separation was most effective when the stirring speed for emulsification was 900 rpm and the stirring speed in mixing the emulsion with the solvent was 150 rpm. 4. The separation of benzene reached a maximum value at the surfactant concentration of 0.2 weight per cent and contact time of 10 minutes. 5. The permeability of benzene was most effective at the concentration of 50 weight percent. 6. To achieve effective separation, it is important to choose proper mixing speed depending on the glycerol concentration.
Effect of Duck-meat Intake on Adult Disease Risk Factors in Adult Human Males
Sung Ho Kang,Oun Hyun Kim,Chang Jin Lee,Ho Sung Jung,Young Tae Lim,Hyuk Song,Si Heung Sung 한국축산식품학회 2010 한국축산식품학회지 Vol.30 No.6
This study was conducted to evaluate the effects of duck-meat consumption on adult disease risk factors, including body compositions, hematological variables, and serum metabolic and lipid profiles in adult human males. To obtain results, 20 adult males aged 20 to 25 were subjected to a diet of 600 g/day of duck-meat for 4 wk, after which body composition, hematological variables, and serum metabolic and lipid profiles were investigated to determine if there was a relationship between duck-meat consumption and adult disease risk factors. The results revealed that high amounts of duck-meat intake did not negatively alter body indices such as body weight, fat mass, body mass index (BMI), % body fat or waste-to-hip ratio (WHR). Furthermore, there were statistically insignificant changes in the number of blood cells, although this number did increase significantly following intake of duck-meat. Moreover, general decreases in serum metabolic parameters were observed, but none of these changes were significant with the exception of the concentration of blood urea nitrogen (BUN). The serum concentrations of LDL-cholesterol also showed a statistically significant decrease by 5.86%. Therefore, this study suggests that the ingestion of duck-meat not only significantly increased the RBC count but also decreased BUN and LDL-cholesterol concentrations in adult males.
Sung-Won Kim,Seng-Oun Sung,Kil Sung Chae,Hwa-Seung Park,Sang-Hoon Lee 대한뇌혈관외과학회 2015 Journal of Cerebrovascular and Endovascular Neuros Vol.17 No.3
Objective: The purpose of this study was to compare clinical findings and outcomes of Enterprise and Solitaire stent-assisted coiling (SAC). Materials and Methods: Between January 2012 and March 2014, 86 patients (mean age, 60.3 years) harboring 89 aneurysms were treated with Enterprise (n = 57) or Solitaire (n = 32) SAC. The patients' demographics, angiographic results, and clinical outcomes were reviewed retrospectively. Results: There were no cases of stent navigation, deployment failure, arterial dissection, or intraoperative aneurysmal rupture. Angiographic follow-up imaging was available for 86 (96.6%) aneurysms (Enterprise group, n = 55; Solitaire group, n = 31). Immediate postoperative and follow-up angiographic results showed no flow or only minimal flow into the neck in 83% (Enterprise group, 77.2%; Solitaire group, 93.8%) and 95.3% (Enterprise group, 92.7%; Solitaire group, 100%) of SAC-treated aneurysms, respectively. Both stent groups showed good immediate postoperative and follow-up clinical outcomes. Excepting 2 cases, all patients achieved modified Rankin Scale scores of 0. Coil loop or tail protrusion into the parent artery was observed in 17 (29.8%) and 7 (21.9%) cases in the Enterprise and Solitaire groups, respectively. No statistically significant difference in terms of angiographic results or clinical outcomes was observed between the groups. Conclusion: Excellent and comparable clinical and angiographic outcomes for wide-neck intracranial aneurysms were achieved using both stents. Because of its higher radial strength and better vessel wall apposition, we cautiously propose that the Solitaire stent may be more effective for SAC of aneurysms harboring a large or severe tortuous parent artery.
Antioxidant Activity of Porcine Skin Gelatin Hydrolyzed by Pepsin and Pancreatin
Oun Ki Chang,Go Eun Ha,Seok Geun Jeong,Kuk Hwan Seol,Mi Hwa Oh,Dong Wook Kim,Ae Ra Jang,Sae Hun Kim,Beom Young Park,Jun Sang Ham 한국축산식품학회 2013 한국축산식품학회지 Vol.33 No.4
Gelatin is a collagen-containing thermohydrolytic substance commonly incorporated in cosmetic and pharmaceutical products. This study investigated the antioxidant activity of gelatin by using different reagents, such as 2,2-azinobis-(3-ethylbenzothiazoline- 6-sulfonic acid) (ABTS), 2,2-di (4-tert-octylphenyl)-1-picrylhydrazyl (DPPH), and oxygen radical absorbance capacity-fluorescein (ORAC-FL) in a porcine gelatin hydrolysate obtained using gastrointestinal enzymes. Electrophoretic analysis of the gelatin hydrolysis products showed extensive degradation by pepsin and pancreatin, resulting in an increase in the peptide concentration (12.1 mg/mL). Antioxidant activity, as measured by ABTS, exhibited the highest values after 48-h incubation with pancreatin treatment after pepsin digestion. Similar effects were observed at 48 h incubation, that is, 61.5% for the DPPH assay and 69.3% for the ABTS assay. However, the gallic acid equivalent (GE) at 48 h was 87.8 μM, whereas 14.5 μM GE was obtained using the ABTS and DPPH assays, indicating about sixfold increase. In the ORACFL assay, antioxidant activity corresponding to 45.7 μM of trolox equivalent was found in the gelatin hydrolysate after 24 h hydrolysis with pancreatin treatment after pepsin digestion, whereas this activity decreased at 48 h. These antioxidant assay results showed that digestion of gelatin by gastrointestinal enzymes prevents oxidative damage.